RHD Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description Rh blood group, D antigen|The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene, which encodes the RhD protein, and a second gene that encodes both the RhC and RhE antigens on a single polypeptide. The two genes, and a third unrelated gene, are found in a cluster on chromosome 1. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6007)
External Link https://ncbi.nlm.nih.gov/gene/6007
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Genes

499 genes differentially expressed following the RHD gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
PTK2 protein tyrosine kinase 2 0.0221856
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.0210963
MECOM MDS1 and EVI1 complex locus 0.0151697
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.0141379
DACH1 dachshund family transcription factor 1 0.0134193
LAMP5 lysosomal-associated membrane protein family, member 5 0.0132205
ASCL1 achaete-scute family bHLH transcription factor 1 0.0114174
CXCL14 chemokine (C-X-C motif) ligand 14 0.0109819
BEX1 brain expressed, X-linked 1 0.0108973
PSIP1 PC4 and SFRS1 interacting protein 1 0.0105657
ZDHHC6 zinc finger, DHHC-type containing 6 0.010418
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 0.0103786
CIT citron rho-interacting serine/threonine kinase 0.0102838
AUTS2 autism susceptibility candidate 2 0.0101603
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 0.0100926
RGS5 regulator of G-protein signaling 5 0.0100366
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 0.00987328
ITM2C integral membrane protein 2C 0.00978249
HMGB2 high mobility group box 2 0.00970437
DDHD2 DDHD domain containing 2 0.00958399
PCSK1 proprotein convertase subtilisin/kexin type 1 0.00949059
IL17RB interleukin 17 receptor B 0.00948968
ACSL5 acyl-CoA synthetase long-chain family member 5 0.00948901
MYO5C myosin VC 0.00934601
CD99 CD99 molecule 0.00932229
KLHL23 kelch-like family member 23 0.0093092
MYH11 myosin, heavy chain 11, smooth muscle 0.00923523
SDC2 syndecan 2 0.00922527
DHFR dihydrofolate reductase 0.00912109
SEPTIN10 septin 10 0.00908396
RAD21 RAD21 homolog (S. pombe) 0.00902847
PBK PDZ binding kinase 0.00898087
ENC1 ectodermal-neural cortex 1 (with BTB domain) 0.00896495
AGR2 anterior gradient 2 0.00892512
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 0.00889484
HMGB1 high mobility group box 1 0.00887967
EPCAM epithelial cell adhesion molecule 0.00886236
SRSF1 serine/arginine-rich splicing factor 1 0.00884653
MAP2K6 mitogen-activated protein kinase kinase 6 0.00884565
FASN fatty acid synthase 0.00877461
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 0.00873102
SNAP25 synaptosomal-associated protein, 25kDa 0.00871583
CPE carboxypeptidase E 0.00870023
MBL2 mannose-binding lectin (protein C) 2, soluble 0.00869162
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.00848816
GINS2 GINS complex subunit 2 (Psf2 homolog) 0.00848531
GPM6A glycoprotein M6A 0.00845836
INSM1 insulinoma-associated 1 0.00841563
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 0.00839132
PLK1 polo-like kinase 1 0.00836461
SYBU syntabulin (syntaxin-interacting) 0.00830661
PLAT plasminogen activator, tissue 0.00830143
HMGB3 high mobility group box 3 0.00830019
SPINK1 serine peptidase inhibitor, Kazal type 1 0.00829917
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.00829605
NAE1 NEDD8 activating enzyme E1 subunit 1 0.00827234
TARDBP TAR DNA binding protein 0.00812692
SNX7 sorting nexin 7 0.00812674
FABP1 fatty acid binding protein 1, liver 0.0080693
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.00805689
ATAD2 ATPase family, AAA domain containing 2 0.00798851
PLN phospholamban 0.00798541
SPON1 spondin 1, extracellular matrix protein 0.00798045
SPC25 SPC25, NDC80 kinetochore complex component 0.00791286
SRP9 signal recognition particle 9kDa 0.0078841
CLCA1 chloride channel accessory 1 0.00787122
OLFM1 olfactomedin 1 0.00784968
SQLE squalene epoxidase 0.00784123
CALD1 caldesmon 1 0.00782102
NR2F1 nuclear receptor subfamily 2, group F, member 1 0.0078017
MAP7 microtubule-associated protein 7 0.00780025
EMP2 epithelial membrane protein 2 0.0077859
COL1A2 collagen, type I, alpha 2 0.00774838
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0077397
PEG3 paternally expressed 3 0.00767345
DUT deoxyuridine triphosphatase 0.00767231
GPM6B glycoprotein M6B 0.00766887
INSIG1 insulin induced gene 1 0.00763172
ARPP19 cAMP-regulated phosphoprotein, 19kDa 0.0076092
MGP matrix Gla protein 0.00760236
THAP12 THAP domain containing 12 0.00757177
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 0.00757065
NFASC neurofascin 0.00754346
SPATS2L spermatogenesis associated, serine-rich 2-like 0.00751584
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.00750189
ANOS1 anosmin 1 0.00745189
SPIN1 spindlin 1 0.00744022
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.0073853
ADAM28 ADAM metallopeptidase domain 28 0.00734821
TFF3 trefoil factor 3 (intestinal) 0.0072814
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 0.0072717
AEBP1 AE binding protein 1 0.00726662
EXPH5 exophilin 5 0.00724826
SPA17 sperm autoantigenic protein 17 0.00724825
AP1S2 adaptor-related protein complex 1, sigma 2 subunit 0.00724824
RAD51AP1 RAD51 associated protein 1 0.00720933
OIP5 Opa interacting protein 5 0.00720795
TMEM176A transmembrane protein 176A 0.00714362
GLO1 glyoxalase I 0.00713427
S100B S100 calcium binding protein B 0.00713284
METTL5 methyltransferase like 5 0.00712367
FZD5 frizzled class receptor 5 0.00711879
DCK deoxycytidine kinase 0.00711644
CALML4 calmodulin-like 4 0.0071023
KIF14 kinesin family member 14 0.00708735
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.00706335
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E 0.00705954
CCNA2 cyclin A2 0.00705435
CBX1 chromobox homolog 1 0.00703251
CRY1 cryptochrome circadian clock 1 0.00700093
IPO5 importin 5 0.00699112
ASRGL1 asparaginase like 1 0.00699023
GPR88 G protein-coupled receptor 88 0.00693892
COLEC12 collectin sub-family member 12 0.00692541
MATN2 matrilin 2 0.00691669
SDHAF3 succinate dehydrogenase complex assembly factor 3 0.00691523
TFDP1 transcription factor Dp-1 0.00690786
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 0.00688405
PTGIS prostaglandin I2 (prostacyclin) synthase 0.00684967
DLK1 delta-like 1 homolog (Drosophila) 0.00684673
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 0.00683969
DEK DEK proto-oncogene 0.00680221
GPC3 glypican 3 0.00679889
DPYSL3 dihydropyrimidinase-like 3 0.00679063
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 0.00679034
BARD1 BRCA1 associated RING domain 1 0.00677126
KIF20A kinesin family member 20A 0.00675598
NUSAP1 nucleolar and spindle associated protein 1 0.00674983
ASF1B anti-silencing function 1B histone chaperone 0.00672885
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B 0.0067287
CDC45 cell division cycle 45 0.00672105
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 0.00671453
ADGRF5 adhesion G protein-coupled receptor F5 0.00671284
RBBP4 retinoblastoma binding protein 4 0.00668338
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.00664012
ACAT2 acetyl-CoA acetyltransferase 2 0.00663592
MEN1 multiple endocrine neoplasia I 0.00662081
TJP2 tight junction protein 2 0.0066208
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 0.00661965
FOXF1 forkhead box F1 0.00661479
SYNJ2BP synaptojanin 2 binding protein 0.00659527
METTL7A methyltransferase like 7A 0.00659349
EXOC5 exocyst complex component 5 0.00653401
TMEM204 transmembrane protein 204 0.00652343
MRPL13 mitochondrial ribosomal protein L13 0.00651367
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 0.00651344
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.00651146
SERINC5 serine incorporator 5 0.00648804
TSPAN7 tetraspanin 7 0.00648313
SCGN secretagogin, EF-hand calcium binding protein 0.00647753
SRSF7 serine/arginine-rich splicing factor 7 0.00647578
SV2C synaptic vesicle glycoprotein 2C 0.00647088
ACTA2 actin, alpha 2, smooth muscle, aorta 0.00646986
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 0.00646403
PKP2 plakophilin 2 0.00645532
MERTK MER proto-oncogene, tyrosine kinase 0.00644934
UBE2N ubiquitin-conjugating enzyme E2N 0.00643304
SNCAIP synuclein, alpha interacting protein 0.00642889
CHGA chromogranin A 0.00641913
DBF4 DBF4 zinc finger 0.00641682
FAM198B family with sequence similarity 198, member B 0.00641044
RPS4Y1 ribosomal protein S4, Y-linked 1 0.00639992
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) 0.00639815
FBXO5 F-box protein 5 0.00639106
ASPN asporin 0.00638031
PNN pinin, desmosome associated protein 0.0063704
TPPP3 tubulin polymerization-promoting protein family member 3 0.00636134
GSTO1 glutathione S-transferase omega 1 0.00634528
SLC26A2 solute carrier family 26 (anion exchanger), member 2 0.00633177
FRZB frizzled-related protein 0.00631226
LUC7L3 LUC7-like 3 (S. cerevisiae) 0.00630139
PODXL podocalyxin-like 0.00629872
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.00629435
YEATS4 YEATS domain containing 4 0.00628647
SRSF6 serine/arginine-rich splicing factor 6 0.00628359
TRPS1 trichorhinophalangeal syndrome I 0.00627877
TRMT5 tRNA methyltransferase 5 0.00625806
PDLIM3 PDZ and LIM domain 3 0.0062578
CCL14 chemokine (C-C motif) ligand 14 0.00624313
IFITM1 interferon induced transmembrane protein 1 0.00623991
EIF3E eukaryotic translation initiation factor 3, subunit E 0.00623479
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.00623284
VIL1 villin 1 0.00623247
PTGES3 prostaglandin E synthase 3 (cytosolic) 0.00622653
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.00619369
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2 0.00618897
SYT1 synaptotagmin I 0.00617929
COL2A1 collagen, type II, alpha 1 0.00617567
RCN2 reticulocalbin 2, EF-hand calcium binding domain 0.00617113
PTCH1 patched 1 0.00616656
TMEM176B transmembrane protein 176B 0.0061659
SCD5 stearoyl-CoA desaturase 5 0.00615934
CLEC2B C-type lectin domain family 2, member B 0.00612202
NDP Norrie disease (pseudoglioma) 0.00604326
NR2F6 nuclear receptor subfamily 2, group F, member 6 0.00603772
FAR2 fatty acyl CoA reductase 2 0.00602296
SPAG5 sperm associated antigen 5 0.00601851
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.00601214
CEP43 centrosomal protein 43 0.00600598
BZW1 basic leucine zipper and W2 domains 1 0.00600224
CARMIL1 capping protein regulator and myosin 1 linker 1 0.00597523
RGS10 regulator of G-protein signaling 10 0.00597451
FTO fat mass and obesity associated 0.005961
CYC1 cytochrome c-1 0.00596006
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.00593348
NSD2 nuclear receptor binding SET domain protein 2 0.00592456
CAPRIN1 cell cycle associated protein 1 0.00592006
HNRNPR heterogeneous nuclear ribonucleoprotein R 0.00591942
PCP4 Purkinje cell protein 4 0.00591638
HOXB6 homeobox B6 0.0059098
PLP1 proteolipid protein 1 0.00590167
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.00589771
DOCK4 dedicator of cytokinesis 4 0.00588495
RBBP7 retinoblastoma binding protein 7 0.00587961
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 0.00587501
ADGRA3 adhesion G protein-coupled receptor A3 0.00587414
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.00586835
GIMAP6 GTPase, IMAP family member 6 0.00586581
PIMREG PICALM interacting mitotic regulator 0.00586569
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.00586251
NEIL3 nei endonuclease VIII-like 3 (E. coli) 0.00586231
CRLF1 cytokine receptor-like factor 1 0.00586165
SH3BP4 SH3-domain binding protein 4 0.00584464
TDP2 tyrosyl-DNA phosphodiesterase 2 0.00583766
CHGB chromogranin B 0.00583751
AP5M1 adaptor-related protein complex 5, mu 1 subunit 0.0058309
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.00583037
SLIT2 slit homolog 2 (Drosophila) 0.00582956
FAM120A family with sequence similarity 120A 0.00582785
DPYSL2 dihydropyrimidinase-like 2 0.00581911
LDLRAD4 low density lipoprotein receptor class A domain containing 4 0.0058151
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 0.0058129
ZC3HAV1 zinc finger CCCH-type, antiviral 1 0.00581032
COMMD10 COMM domain containing 10 0.00580837
HMGN5 high mobility group nucleosome binding domain 5 0.00580484
CCR1 chemokine (C-C motif) receptor 1 0.00579667
MPPED2 metallophosphoesterase domain containing 2 0.00579641
RUFY3 RUN and FYVE domain containing 3 0.00579369
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.00576824
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A 0.00576146
PSAT1 phosphoserine aminotransferase 1 0.0057562
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 0.00575051
MTUS1 microtubule associated tumor suppressor 1 0.00574803
TXNIP thioredoxin interacting protein 0.00574687
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.00573825
CPB1 carboxypeptidase B1 (tissue) 0.00573764
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 0.00573633
TPSAB1 tryptase alpha/beta 1 0.00573284
PLXNA2 plexin A2 0.00573001
MCF2L MCF.2 cell line derived transforming sequence-like 0.00572051

decreased expression

Symbol Name Standardized Value
GLOD4 glyoxalase domain containing 4 -0.0226395
S100A9 S100 calcium binding protein A9 -0.0184739
S100A8 S100 calcium binding protein A8 -0.0181074
CRYAB crystallin, alpha B -0.0177276
KYNU kynureninase -0.0157499
JMJD6 jumonji domain containing 6 -0.0151948
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.0149418
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.0145366
KRT14 keratin 14, type I -0.0143507
KRT7 keratin 7, type II -0.0142089
MT1X metallothionein 1X -0.0139799
FOSL2 FOS-like antigen 2 -0.0134874
DEFB1 defensin, beta 1 -0.0134429
S100A12 S100 calcium binding protein A12 -0.013187
ALCAM activated leukocyte cell adhesion molecule -0.0127661
TPD52L1 tumor protein D52-like 1 -0.0127086
KRT15 keratin 15, type I -0.01263
TACSTD2 tumor-associated calcium signal transducer 2 -0.0123861
MT1G metallothionein 1G -0.0122195
DUSP5 dual specificity phosphatase 5 -0.0121814
CSTA cystatin A (stefin A) -0.0120301
PDZK1IP1 PDZK1 interacting protein 1 -0.0119752
SLPI secretory leukocyte peptidase inhibitor -0.0119555
RND3 Rho family GTPase 3 -0.0113889
AREG amphiregulin -0.0113741
CLCA2 chloride channel accessory 2 -0.0111672
ATF3 activating transcription factor 3 -0.0110924
MT1HL1 metallothionein 1H-like 1 -0.0110713
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 -0.0109211
TRIM16 tripartite motif containing 16 -0.0108186
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.0107258
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 -0.0107247
S100A7 S100 calcium binding protein A7 -0.0106735
KRT17 keratin 17, type I -0.0106092
LTF lactotransferrin -0.0105118
TFPI2 tissue factor pathway inhibitor 2 -0.0104504
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 -0.010413
LBH limb bud and heart development -0.010246
KRT5 keratin 5, type II -0.0102139
ZNF185 zinc finger protein 185 (LIM domain) -0.0101833
MT1H metallothionein 1H -0.01014
CD40 CD40 molecule, TNF receptor superfamily member 5 -0.0100492
SGK1 serum/glucocorticoid regulated kinase 1 -0.0100082
MT2A metallothionein 2A -0.00996956
P3H2 prolyl 3-hydroxylase 2 -0.00994602
SIK1 salt-inducible kinase 1 -0.00991332
LCN2 lipocalin 2 -0.00988761
HBD hemoglobin, delta -0.0098772
RRAGD Ras-related GTP binding D -0.00985235
ANXA1 annexin A1 -0.00982948
IFI27 interferon, alpha-inducible protein 27 -0.0098156
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 -0.00977642
PLK2 polo-like kinase 2 -0.00975691
MT1F metallothionein 1F -0.00970265
AQP3 aquaporin 3 (Gill blood group) -0.00966425
GPX3 glutathione peroxidase 3 -0.00965727
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.00949663
CXCL13 chemokine (C-X-C motif) ligand 13 -0.00939352
IL1RN interleukin 1 receptor antagonist -0.00938061
NIBAN1 niban apoptosis regulator 1 -0.00934798
IER5 immediate early response 5 -0.00931279
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0092815
TUFT1 tuftelin 1 -0.00925023
IRS2 insulin receptor substrate 2 -0.00921953
ZMAT3 zinc finger, matrin-type 3 -0.00921155
CRISP3 cysteine-rich secretory protein 3 -0.00920768
PLBD1 phospholipase B domain containing 1 -0.00919197
MIR22HG MIR22 host gene -0.00916099
PPP1R15A protein phosphatase 1, regulatory subunit 15A -0.00913985
MMP7 matrix metallopeptidase 7 -0.00911247
GADD45A growth arrest and DNA-damage-inducible, alpha -0.00904798
NEU1 sialidase 1 (lysosomal sialidase) -0.00901318
HMOX1 heme oxygenase 1 -0.00900253
KRT6A keratin 6A, type II -0.00893621
ATG101 autophagy related 101 -0.00891971
GPNMB glycoprotein (transmembrane) nmb -0.00890036
PTP4A1 protein tyrosine phosphatase type IVA, member 1 -0.00883498
CXCL8 chemokine (C-X-C motif) ligand 8 -0.00865903
GPR137B G protein-coupled receptor 137B -0.00863339
CTSG cathepsin G -0.00860085
BIK BCL2-interacting killer (apoptosis-inducing) -0.00853872
ELANE elastase, neutrophil expressed -0.00852316
KRT16 keratin 16, type I -0.0084397
FXYD3 FXYD domain containing ion transport regulator 3 -0.00843957
LY75 lymphocyte antigen 75 -0.00841283
CA2 carbonic anhydrase II -0.00829365
HSPA1A heat shock 70kDa protein 1A -0.00827346
STC2 stanniocalcin 2 -0.00821867
SCPEP1 serine carboxypeptidase 1 -0.00818563
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 -0.0081507
MAGEA3 melanoma antigen family A3 -0.00813757
ACADVL acyl-CoA dehydrogenase, very long chain -0.00812437
EPHA2 EPH receptor A2 -0.00809442
CCL5 chemokine (C-C motif) ligand 5 -0.00808703
PDGFC platelet derived growth factor C -0.00805614
TARP TCR gamma alternate reading frame protein -0.0080314
TNIP1 TNFAIP3 interacting protein 1 -0.00801131
GSTP1 glutathione S-transferase pi 1 -0.00797294
KLK11 kallikrein-related peptidase 11 -0.00796647
KLF11 Kruppel-like factor 11 -0.00796179
CCN3 cellular communication network factor 3 -0.00795675
KRT13 keratin 13, type I -0.00792262
BIRC3 baculoviral IAP repeat containing 3 -0.00790899
PKP1 plakophilin 1 -0.00787123
KRT6B keratin 6B, type II -0.00784488
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.00781201
RRAGC Ras-related GTP binding C -0.00781053
APOL1 apolipoprotein L, 1 -0.00780381
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) -0.00777038
TMEM45A transmembrane protein 45A -0.00775555
CXCL6 chemokine (C-X-C motif) ligand 6 -0.00775388
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 -0.00775198
ZC3H12A zinc finger CCCH-type containing 12A -0.00774078
GABARAPL1 GABA(A) receptor-associated protein like 1 -0.00770904
PLXNB2 plexin B2 -0.00769379
PSAP prosaposin -0.00765553
PDE8B phosphodiesterase 8B -0.00763879
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.00762802
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain -0.00762717
VEGFC vascular endothelial growth factor C -0.0076047
MVP major vault protein -0.00760045
JCHAIN joining chain of multimeric IgA and IgM -0.00758768
BICC1 BicC family RNA binding protein 1 -0.00758728
CST7 cystatin F (leukocystatin) -0.00756563
RHCG Rh family, C glycoprotein -0.00753546
MITF microphthalmia-associated transcription factor -0.00748842
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -0.00748731
SPRR1B small proline-rich protein 1B -0.0074694
TRIP6 thyroid hormone receptor interactor 6 -0.0074461
GRN granulin -0.00743907
BLVRB biliverdin reductase B -0.00743365
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 -0.007429
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 -0.0074273
TNNC1 troponin C type 1 (slow) -0.00741507
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) -0.00737741
RBM47 RNA binding motif protein 47 -0.0073738
ABHD4 abhydrolase domain containing 4 -0.00737242
ACP3 acid phosphatase 3 -0.00732195
KRT23 keratin 23, type I -0.00730309
CXCL5 chemokine (C-X-C motif) ligand 5 -0.00727684
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 -0.00726313
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 -0.00723776
HSPB8 heat shock 22kDa protein 8 -0.00722831
G6PD glucose-6-phosphate dehydrogenase -0.00719804
TUBA4A tubulin, alpha 4a -0.00718383
RHOD ras homolog family member D -0.00714624
PFKP phosphofructokinase, platelet -0.00713764
CAV2 caveolin 2 -0.00711315
CLIC3 chloride intracellular channel 3 -0.00710627
SDC4 syndecan 4 -0.00710504
DEFA4 defensin, alpha 4, corticostatin -0.0070975
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -0.00708855
SPRR3 small proline-rich protein 3 -0.00705512
PPIF peptidylprolyl isomerase F -0.00705069
MT1M metallothionein 1M -0.00704765
CTSD cathepsin D -0.00704563
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene -0.00704411
RHOF ras homolog family member F (in filopodia) -0.00703436
KLK10 kallikrein-related peptidase 10 -0.00702272
TGFA transforming growth factor, alpha -0.00701841
LYPD3 LY6/PLAUR domain containing 3 -0.00700436
FTH1 ferritin, heavy polypeptide 1 -0.00698287
PLAUR plasminogen activator, urokinase receptor -0.00698051
MGLL monoglyceride lipase -0.00696959
ARMCX6 armadillo repeat containing, X-linked 6 -0.00695622
PI3 peptidase inhibitor 3, skin-derived -0.00694382
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -0.00694128
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) -0.00693718
KRT8 keratin 8, type II -0.0069344
ELOVL1 ELOVL fatty acid elongase 1 -0.00692349
GJA1 gap junction protein, alpha 1, 43kDa -0.00688584
CDH13 cadherin 13 -0.00685761
UROD uroporphyrinogen decarboxylase -0.0068435
VCL vinculin -0.00684253
BTF3P11 basic transcription factor 3 pseudogene 11 -0.00684008
MRM3 mitochondrial rRNA methyltransferase 3 -0.00683984
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 -0.00680881
CA12 carbonic anhydrase XII -0.00680421
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.00678622
ENAH enabled homolog (Drosophila) -0.00678514
WDR13 WD repeat domain 13 -0.00673699
CDA cytidine deaminase -0.00673465
C5AR1 complement component 5a receptor 1 -0.00673445
CLTB clathrin, light chain B -0.00672422
LAMB3 laminin, beta 3 -0.00672067
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) -0.00671576
KIAA0355 KIAA0355 -0.00671093
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.0067053
BEX4 brain expressed, X-linked 4 -0.0067027
NXN nucleoredoxin -0.00669809
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.00669352
MME membrane metallo-endopeptidase -0.00668027
CRCT1 cysteine-rich C-terminal 1 -0.00666538
ZBED2 zinc finger, BED-type containing 2 -0.00666512
IL15 interleukin 15 -0.00666498
MT1E metallothionein 1E -0.00662526
SPRR1A small proline-rich protein 1A -0.0066129
IGLL1 immunoglobulin lambda-like polypeptide 1 -0.00658711
YPEL5 yippee-like 5 (Drosophila) -0.00658414
TRIM29 tripartite motif containing 29 -0.00657529
VNN1 vanin 1 -0.00655636
TMED3 transmembrane emp24 protein transport domain containing 3 -0.0065535
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 -0.00654993
ZYX zyxin -0.00654634
NLRP2 NLR family, pyrin domain containing 2 -0.00651628
RUNX3 runt-related transcription factor 3 -0.00650971
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13 -0.00650588
TSPO translocator protein (18kDa) -0.00650341
EIF5A eukaryotic translation initiation factor 5A -0.00649795
G0S2 G0/G1 switch 2 -0.00649319
ZSWIM8 zinc finger, SWIM-type containing 8 -0.00648388
CEBPB CCAAT/enhancer binding protein (C/EBP), beta -0.00647699
S100A11 S100 calcium binding protein A11 -0.00646724
PPP1R3C protein phosphatase 1, regulatory subunit 3C -0.00645796
NAGK N-acetylglucosamine kinase -0.00645735
CXCL10 chemokine (C-X-C motif) ligand 10 -0.00645609
ADM adrenomedullin -0.00645089
SPRR2B small proline-rich protein 2B -0.00643558
SCEL sciellin -0.00643524
MBOAT2 membrane bound O-acyltransferase domain containing 2 -0.00642803
PTHLH parathyroid hormone-like hormone -0.00641262
RIPK2 receptor-interacting serine-threonine kinase 2 -0.00641129
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 -0.00640095
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) -0.00638655
ZNF281 zinc finger protein 281 -0.00636204
MAGEA4 melanoma antigen family A4 -0.00636
ENO3 enolase 3 (beta, muscle) -0.00635909
PRSS21 protease, serine, 21 (testisin) -0.00635519
ADGRE5 adhesion G protein-coupled receptor E5 -0.00635319
NPC2 Niemann-Pick disease, type C2 -0.00635278
FOSB FBJ murine osteosarcoma viral oncogene homolog B -0.0063445
MFSD1 major facilitator superfamily domain containing 1 -0.00634094
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -0.0063259
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 -0.00632154
UBE2L6 ubiquitin-conjugating enzyme E2L 6 -0.00631949
EMC3 ER membrane protein complex subunit 3 -0.00631749
LY6D lymphocyte antigen 6 complex, locus D -0.00628293
SMG7 SMG7 nonsense mediated mRNA decay factor -0.00627302
CTSA cathepsin A -0.00624213
CRK v-crk avian sarcoma virus CT10 oncogene homolog -0.0062303
NT5E 5'-nucleotidase, ecto (CD73) -0.00622
FOLR1 folate receptor 1 (adult) -0.00621747
TMEM147 transmembrane protein 147 -0.0062141
DSG3 desmoglein 3 -0.00618074
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 -0.00617889
CD38 CD38 molecule -0.00617838
CKM creatine kinase, muscle -0.00615342
PTGER4 prostaglandin E receptor 4 (subtype EP4) -0.00615223
ECM1 extracellular matrix protein 1 -0.00614813