RHO Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description rhodopsin|Retinitis pigmentosa is an inherited progressive disease which is a major cause of blindness in western communities. It can be inherited as an autosomal dominant, autosomal recessive, or X-linked recessive disorder. In the autosomal dominant form,which comprises about 25% of total cases, approximately 30% of families have mutations in the gene encoding the rod photoreceptor-specific protein rhodopsin. This is the transmembrane protein which, when photoexcited, initiates the visual transduction cascade. Defects in this gene are also one of the causes of congenital stationary night blindness. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6010)
External Link https://ncbi.nlm.nih.gov/gene/6010
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Genes

498 genes differentially expressed following the RHO gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
CA2 carbonic anhydrase II 0.0157841
XIC X chromosome inactivation center 0.012886
PCNA proliferating cell nuclear antigen 0.0125572
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 0.0120425
GREM1 gremlin 1, DAN family BMP antagonist 0.0118832
DMTF1 cyclin D binding myb-like transcription factor 1 0.0116818
HIST1H2BD histone cluster 1, H2bd 0.0113919
PLIN2 perilipin 2 0.0112007
HSPA1A heat shock 70kDa protein 1A 0.0111141
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.0109119
GOLM1 golgi membrane protein 1 0.0108329
SLC38A1 solute carrier family 38, member 1 0.0108272
CTSA cathepsin A 0.0107975
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.0107029
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 0.010679
PDE8A phosphodiesterase 8A 0.0105987
DUSP5 dual specificity phosphatase 5 0.010539
TPBG trophoblast glycoprotein 0.0104189
EZR ezrin 0.010297
TFF1 trefoil factor 1 0.0102555
MMP3 matrix metallopeptidase 3 0.0102059
HEPH hephaestin 0.0101508
CA12 carbonic anhydrase XII 0.0101239
SLC25A46 solute carrier family 25, member 46 0.0100687
HIST1H2AC histone cluster 1, H2ac 0.0100419
REG1A regenerating islet-derived 1 alpha 0.00990779
CREM cAMP responsive element modulator 0.00989668
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 0.00980283
EGR1 early growth response 1 0.0097915
CD40 CD40 molecule, TNF receptor superfamily member 5 0.00964569
HSPB8 heat shock 22kDa protein 8 0.00957384
GALC galactosylceramidase 0.00952451
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.00950269
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.00947917
ZEB2 zinc finger E-box binding homeobox 2 0.00937007
HIST1H2BK histone cluster 1, H2bk 0.00921296
GATA6 GATA binding protein 6 0.00897797
AKAP12 A kinase (PRKA) anchor protein 12 0.00892872
CTBP2 C-terminal binding protein 2 0.00889291
TTC39A tetratricopeptide repeat domain 39A 0.00886738
SOCS1 suppressor of cytokine signaling 1 0.00885407
ADM adrenomedullin 0.00883394
WFDC1 WAP four-disulfide core domain 1 0.00882428
STX3 syntaxin 3 0.00867158
SLC38A2 solute carrier family 38, member 2 0.0085899
SLC30A1 solute carrier family 30 (zinc transporter), member 1 0.0085249
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.00851192
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.00842523
FKBP4 FK506 binding protein 4, 59kDa 0.00838858
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 0.00838363
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.00828891
RASIP1 Ras interacting protein 1 0.00828042
RHOB ras homolog family member B 0.00827259
EVI2A ecotropic viral integration site 2A 0.00824691
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.00822427
TXNDC9 thioredoxin domain containing 9 0.00818782
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 0.00818421
BASP1 brain abundant, membrane attached signal protein 1 0.00817545
ADIRF adipogenesis regulatory factor 0.00815909
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 0.00814144
HIST1H2BH histone cluster 1, H2bh 0.00810731
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.00804962
FA2H fatty acid 2-hydroxylase 0.00803003
IRF9 interferon regulatory factor 9 0.00792517
ADCY9 adenylate cyclase 9 0.00788654
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked 0.0078808
FTH1 ferritin, heavy polypeptide 1 0.00780907
GAB2 GRB2-associated binding protein 2 0.0077634
DDIT3 DNA-damage-inducible transcript 3 0.00763327
UPP1 uridine phosphorylase 1 0.00762653
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.00761822
SMAD3 SMAD family member 3 0.00759466
HSPA6 heat shock 70kDa protein 6 (HSP70B') 0.00757203
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.00756864
CTSL cathepsin L 0.00755648
SCUBE2 signal peptide, CUB domain, EGF-like 2 0.00753398
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 0.00753099
PTP4A1 protein tyrosine phosphatase type IVA, member 1 0.00753097
RHOF ras homolog family member F (in filopodia) 0.00751038
HIST1H2AE histone cluster 1, H2ae 0.00748321
COL11A1 collagen, type XI, alpha 1 0.00745736
TBX3 T-box 3 0.00742178
FAM13B family with sequence similarity 13, member B 0.0073951
TOB1 transducer of ERBB2, 1 0.00738632
SCGB2A2 secretoglobin, family 2A, member 2 0.00737718
GPR137B G protein-coupled receptor 137B 0.00736417
TUFT1 tuftelin 1 0.00736049
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.00732193
SDC4 syndecan 4 0.00727855
STC1 stanniocalcin 1 0.00727105
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 0.00722694
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 0.007186
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 0.00715932
CYTIP cytohesin 1 interacting protein 0.00715508
KCTD5 potassium channel tetramerization domain containing 5 0.00714709
LITAF lipopolysaccharide-induced TNF factor 0.00712336
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A 0.00711147
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 0.00710788
MYRF myelin regulatory factor 0.00709691
MAP7 microtubule-associated protein 7 0.00708571
RAB9A RAB9A, member RAS oncogene family 0.00707676
QSOX1 quiescin Q6 sulfhydryl oxidase 1 0.00701228
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.00694931
GADD45A growth arrest and DNA-damage-inducible, alpha 0.00694632
CCNG2 cyclin G2 0.00692526
TNIP1 TNFAIP3 interacting protein 1 0.00689822
TRIB3 tribbles pseudokinase 3 0.00687327
RRAGC Ras-related GTP binding C 0.0068479
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 0.00678571
POF1B premature ovarian failure, 1B 0.00678552
IFI27 interferon, alpha-inducible protein 27 0.00677925
IL1R2 interleukin 1 receptor, type II 0.0067777
FGFR2 fibroblast growth factor receptor 2 0.0067746
MGLL monoglyceride lipase 0.00676619
MRPL18 mitochondrial ribosomal protein L18 0.00674533
LOXL2 lysyl oxidase-like 2 0.00672687
TFF3 trefoil factor 3 (intestinal) 0.00671736
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.00671136
SLCO4A1 solute carrier organic anion transporter family, member 4A1 0.00670585
CHN1 chimerin 1 0.00669141
ASS1 argininosuccinate synthase 1 0.00668971
DUSP1 dual specificity phosphatase 1 0.00667201
RGS13 regulator of G-protein signaling 13 0.00664646
COL15A1 collagen, type XV, alpha 1 0.00664144
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.00661019
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.00660974
H1-2 H1.2 linker histone, cluster member 0.00660391
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.0065869
STC2 stanniocalcin 2 0.00658677
SQSTM1 sequestosome 1 0.00657971
GLA galactosidase, alpha 0.00657386
MPO myeloperoxidase 0.00655129
MPDZ multiple PDZ domain protein 0.00654129
BICC1 BicC family RNA binding protein 1 0.00651445
SPAG9 sperm associated antigen 9 0.00648383
PDE2A phosphodiesterase 2A, cGMP-stimulated 0.00646866
OGA O-GlcNAcase 0.00644559
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.00643604
IL6 interleukin 6 0.00643125
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 0.00640205
FNDC3A fibronectin type III domain containing 3A 0.00640093
HSPH1 heat shock 105kDa/110kDa protein 1 0.006397
IL7R interleukin 7 receptor 0.00638031
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 0.00636148
RTN2 reticulon 2 0.00633257
RAB8A RAB8A, member RAS oncogene family 0.00632942
SGK1 serum/glucocorticoid regulated kinase 1 0.00631017
ZG16 zymogen granule protein 16 0.00630409
SS18 synovial sarcoma translocation, chromosome 18 0.00630099
GNG11 guanine nucleotide binding protein (G protein), gamma 11 0.00629116
PHIP pleckstrin homology domain interacting protein 0.00628791
CEP170 centrosomal protein 170kDa 0.00628308
PCDH17 protocadherin 17 0.00626353
PPP4R3A protein phosphatase 4 regulatory subunit 3A 0.00625597
SLC39A8 solute carrier family 39 (zinc transporter), member 8 0.00625431
ASNS asparagine synthetase (glutamine-hydrolyzing) 0.00624563
TPD52L1 tumor protein D52-like 1 0.00621499
HK2 hexokinase 2 0.00621316
MFSD1 major facilitator superfamily domain containing 1 0.00620796
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.00620774
TMEM127 transmembrane protein 127 0.0061991
WSB1 WD repeat and SOCS box containing 1 0.00619841
SLC16A6 solute carrier family 16, member 6 0.00618361
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 0.00617839
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 0.00617434
CLC Charcot-Leyden crystal galectin 0.00616956
PFKP phosphofructokinase, platelet 0.0061565
PTEN phosphatase and tensin homolog 0.00613645
WIPF1 WAS/WASL interacting protein family, member 1 0.00613496
HMOX1 heme oxygenase 1 0.00612205
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 0.0061175
ATG2A autophagy related 2A 0.00611072
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.00609451
PDK4 pyruvate dehydrogenase kinase, isozyme 4 0.00609272
ACKR3 atypical chemokine receptor 3 0.00607817
GOLGA8A golgin A8 family, member A 0.00607218
PAX5 paired box 5 0.00606982
WLS wntless Wnt ligand secretion mediator 0.00605266
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 0.00605102
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 0.00603151
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) 0.0060208
WASHC4 WASH complex subunit 4 0.00600924
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 0.00600719
VNN1 vanin 1 0.00598674
PFDN4 prefoldin subunit 4 0.00597606
TIGAR TP53 induced glycolysis regulatory phosphatase 0.00595082
GNS glucosamine (N-acetyl)-6-sulfatase 0.00594469
DUOX2 dual oxidase 2 0.00593891
CD22 CD22 molecule 0.00593827
PHACTR2 phosphatase and actin regulator 2 0.00593603
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa 0.00593093
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 0.00592963
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 0.00592628
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 0.00592201
MCL1 myeloid cell leukemia 1 0.00591313
CCL4 chemokine (C-C motif) ligand 4 0.00589954
FOSL2 FOS-like antigen 2 0.00589186
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.00587181
APOLD1 apolipoprotein L domain containing 1 0.00586924
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.00586391
KANK1 KN motif and ankyrin repeat domains 1 0.00586362
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 0.00586031
PILRB paired immunoglobin-like type 2 receptor beta 0.00582934
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.00582835
NDNF neuron-derived neurotrophic factor 0.00582407
TMEM131 transmembrane protein 131 0.00582261
TOX3 TOX high mobility group box family member 3 0.00580075
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1 0.00579109
RABEP2 rabaptin, RAB GTPase binding effector protein 2 0.00577632
GAREM1 GRB2 associated regulator of MAPK1 subtype 1 0.0057279
BCAR3 breast cancer anti-estrogen resistance 3 0.00572744
G0S2 G0/G1 switch 2 0.00572533
NR4A2 nuclear receptor subfamily 4, group A, member 2 0.00572424
AFF1 AF4/FMR2 family, member 1 0.00572189
CCDC68 coiled-coil domain containing 68 0.00570754
RIN2 Ras and Rab interactor 2 0.00570545
C21ORF91 chromosome 21 open reading frame 91 0.00569244
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.00568215
UBE2B ubiquitin-conjugating enzyme E2B 0.00567959
KDM6A lysine (K)-specific demethylase 6A 0.00566351
CCP110 centriolar coiled coil protein 110kDa 0.00566294
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.00565628
CXCL5 chemokine (C-X-C motif) ligand 5 0.00564527
NOTCH2 notch 2 0.00564445
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 0.00564235
SNX13 sorting nexin 13 0.00563826
TARP TCR gamma alternate reading frame protein 0.0056307
FGF2 fibroblast growth factor 2 (basic) 0.00562394
NT5C2 5'-nucleotidase, cytosolic II 0.00562268
VEGFC vascular endothelial growth factor C 0.00562186
XBP1 X-box binding protein 1 0.00561665
BTG1 B-cell translocation gene 1, anti-proliferative 0.00560878
MID1IP1 MID1 interacting protein 1 0.00560831
ELANE elastase, neutrophil expressed 0.00560257
SLC31A2 solute carrier family 31 (copper transporter), member 2 0.00558851
HOXB6 homeobox B6 0.00557985
ANKRD12 ankyrin repeat domain 12 0.0055777
MMD monocyte to macrophage differentiation-associated 0.00556244
SCARB2 scavenger receptor class B, member 2 0.00556225
FOXF1 forkhead box F1 0.00555989
CCNA2 cyclin A2 0.00555555
CLCA4 chloride channel accessory 4 0.00554964
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma 0.00554578
TENT5A terminal nucleotidyltransferase 5A 0.0055452
CFD complement factor D (adipsin) 0.00553367
RIT1 Ras-like without CAAX 1 0.00553024
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1 0.00552817
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 0.00551445
STK10 serine/threonine kinase 10 0.00551385

decreased expression

Symbol Name Standardized Value
GNAS GNAS complex locus -0.0219983
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.0178174
NRN1 neuritin 1 -0.0157059
C3 complement component 3 -0.0135601
SEPP1 selenoprotein P, plasma, 1 -0.0135198
MMP7 matrix metallopeptidase 7 -0.0132264
MGP matrix Gla protein -0.0128019
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.0126838
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -0.0126432
CP ceruloplasmin (ferroxidase) -0.0121353
LTF lactotransferrin -0.0119549
FGG fibrinogen gamma chain -0.0119293
SNCA synuclein, alpha (non A4 component of amyloid precursor) -0.011426
KDM5D lysine (K)-specific demethylase 5D -0.0113518
FOXG1 forkhead box G1 -0.0111883
NPY neuropeptide Y -0.0110944
SOX11 SRY (sex determining region Y)-box 11 -0.0110719
MYBPC1 myosin binding protein C, slow type -0.0107038
SLPI secretory leukocyte peptidase inhibitor -0.0106102
RGCC regulator of cell cycle -0.0105902
MUC16 mucin 16, cell surface associated -0.0105644
MAGED1 melanoma antigen family D1 -0.0103602
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.0102729
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.0101563
MSLN mesothelin -0.0101008
TNNC1 troponin C type 1 (slow) -0.00987929
FABP7 fatty acid binding protein 7, brain -0.0098778
KRT5 keratin 5, type II -0.00973901
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.00956431
PADI2 peptidyl arginine deiminase, type II -0.00940496
DLK1 delta-like 1 homolog (Drosophila) -0.00919908
FMO2 flavin containing monooxygenase 2 (non-functional) -0.00918941
A2M alpha-2-macroglobulin -0.00913626
TIMP3 TIMP metallopeptidase inhibitor 3 -0.00911482
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) -0.00910355
S100A2 S100 calcium binding protein A2 -0.00900209
ALB albumin -0.008836
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -0.00873922
MLF1 myeloid leukemia factor 1 -0.00856194
LAPTM4B lysosomal protein transmembrane 4 beta -0.0085271
CD14 CD14 molecule -0.00851491
C1RL complement component 1, r subcomponent-like -0.00850672
YBX3 Y box binding protein 3 -0.00846047
VSIG4 V-set and immunoglobulin domain containing 4 -0.008459
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -0.00845216
TUBA1A tubulin, alpha 1a -0.00845111
SRPX sushi-repeat containing protein, X-linked -0.00841008
BAD BCL2-associated agonist of cell death -0.00830319
BIRC5 baculoviral IAP repeat containing 5 -0.00826687
EMX2 empty spiracles homeobox 2 -0.00816089
ACP6 acid phosphatase 6, lysophosphatidic -0.00815894
PUF60 poly-U binding splicing factor 60KDa -0.00814249
ADD3 adducin 3 (gamma) -0.00803433
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 -0.00802945
PRMT1 protein arginine methyltransferase 1 -0.00800556
KRT19 keratin 19, type I -0.00795594
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.00789474
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein -0.00787856
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) -0.00787754
THYN1 thymocyte nuclear protein 1 -0.00787035
HAMP hepcidin antimicrobial peptide -0.00784982
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 -0.00783841
KRT7 keratin 7, type II -0.00782121
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 -0.00781281
SIRT3 sirtuin 3 -0.00775608
S100A8 S100 calcium binding protein A8 -0.0077323
MOXD1 monooxygenase, DBH-like 1 -0.00766542
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -0.00763617
LAMC1 laminin, gamma 1 (formerly LAMB2) -0.00756345
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -0.00756011
CD59 CD59 molecule, complement regulatory protein -0.00754419
ARID4A AT rich interactive domain 4A (RBP1-like) -0.00751845
MEOX2 mesenchyme homeobox 2 -0.00749477
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -0.00738083
PRKCA protein kinase C, alpha -0.00737851
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00733719
RXYLT1 ribitol xylosyltransferase 1 -0.0073217
BCHE butyrylcholinesterase -0.00730635
COPS7A COP9 signalosome subunit 7A -0.00728723
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -0.007285
LDLRAD4 low density lipoprotein receptor class A domain containing 4 -0.00726289
MRPL12 mitochondrial ribosomal protein L12 -0.0072408
H1-10 H1.10 linker histone -0.00722416
ST14 suppression of tumorigenicity 14 (colon carcinoma) -0.00717217
NDRG2 NDRG family member 2 -0.00714275
FCGRT Fc fragment of IgG, receptor, transporter, alpha -0.00713381
EPAS1 endothelial PAS domain protein 1 -0.007132
MYH10 myosin, heavy chain 10, non-muscle -0.00709998
UBE2S ubiquitin-conjugating enzyme E2S -0.00707947
GIMAP6 GTPase, IMAP family member 6 -0.00706316
AKR1C2 aldo-keto reductase family 1, member C2 -0.00705639
ASPN asporin -0.00698838
ABHD2 abhydrolase domain containing 2 -0.00696806
SELENOW selenoprotein W -0.00696412
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 -0.00695182
SIVA1 SIVA1, apoptosis-inducing factor -0.00694227
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide -0.00691689
MIA melanoma inhibitory activity -0.00689969
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 -0.0068793
PALMD palmdelphin -0.00684545
PWP1 PWP1 homolog (S. cerevisiae) -0.00684299
C10ORF10 chromosome 10 open reading frame 10 -0.00684234
PRUNE2 prune homolog 2 (Drosophila) -0.0068244
E2F2 E2F transcription factor 2 -0.0068231
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 -0.00681803
RIPK4 receptor-interacting serine-threonine kinase 4 -0.00677714
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 -0.00674789
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -0.00674395
PDLIM3 PDZ and LIM domain 3 -0.00673566
APOD apolipoprotein D -0.00673395
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 -0.00671786
AHCY adenosylhomocysteinase -0.0066829
MPZL2 myelin protein zero-like 2 -0.00664199
USP9Y ubiquitin specific peptidase 9, Y-linked -0.00662767
BIN1 bridging integrator 1 -0.00662745
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A -0.00659272
ACTA2 actin, alpha 2, smooth muscle, aorta -0.00658813
COCH cochlin -0.00656086
FOLR1 folate receptor 1 (adult) -0.00653221
PTN pleiotrophin -0.00653037
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 -0.00646656
ACSL5 acyl-CoA synthetase long-chain family member 5 -0.00645089
FAM3C family with sequence similarity 3, member C -0.00643737
ADORA2B adenosine A2b receptor -0.00643532
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 -0.00642629
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) -0.00641265
CD320 CD320 molecule -0.00637493
SLCO2B1 solute carrier organic anion transporter family, member 2B1 -0.00634596
TMEM160 transmembrane protein 160 -0.00634018
CPB2 carboxypeptidase B2 (plasma) -0.00633525
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 -0.00631702
LTA4H leukotriene A4 hydrolase -0.00631667
DMAC2L distal membrane arm assembly component 2 like -0.00630951
HMGB3 high mobility group box 3 -0.00630556
EYA2 EYA transcriptional coactivator and phosphatase 2 -0.00629656
ODAM odontogenic, ameloblast asssociated -0.00629526
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 -0.00628546
APOA1 apolipoprotein A-I -0.00628326
TNNI2 troponin I type 2 (skeletal, fast) -0.00627794
NT5DC2 5'-nucleotidase domain containing 2 -0.00626383
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 -0.00626084
PITX3 paired-like homeodomain 3 -0.00625944
AQP4 aquaporin 4 -0.00625344
PLK1 polo-like kinase 1 -0.00622072
WDR61 WD repeat domain 61 -0.00620851
AKAP7 A kinase (PRKA) anchor protein 7 -0.00620281
RPIA ribose 5-phosphate isomerase A -0.00620003
ATP6V0E2 ATPase, H+ transporting V0 subunit e2 -0.00619534
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) -0.00617812
MAP2K6 mitogen-activated protein kinase kinase 6 -0.00617144
TM6SF1 transmembrane 6 superfamily member 1 -0.00613875
AK4 adenylate kinase 4 -0.00609838
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -0.0060853
GYPC glycophorin C (Gerbich blood group) -0.00608466
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -0.0060822
DOK5 docking protein 5 -0.0060795
HOPX HOP homeobox -0.0060761
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 -0.0060676
SFTPD surfactant protein D -0.00605632
DCXR dicarbonyl/L-xylulose reductase -0.00602867
KRT6A keratin 6A, type II -0.00602294
RAB25 RAB25, member RAS oncogene family -0.0060082
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 -0.00600251
EHBP1 EH domain binding protein 1 -0.00599491
HP haptoglobin -0.0059834
HPF1 histone PARylation factor 1 -0.00597438
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A -0.00596995
MFAP5 microfibrillar associated protein 5 -0.00593303
ASRGL1 asparaginase like 1 -0.00592318
ADGRG2 adhesion G protein-coupled receptor G2 -0.00592253
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -0.00589294
LAPTM5 lysosomal protein transmembrane 5 -0.00588335
APOB apolipoprotein B -0.00588314
CHI3L2 chitinase 3-like 2 -0.00587964
CDC20 cell division cycle 20 -0.00587534
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) -0.00587447
TPM3 tropomyosin 3 -0.00587269
CPVL carboxypeptidase, vitellogenic-like -0.00586244
APOH apolipoprotein H (beta-2-glycoprotein I) -0.00583498
SCRG1 stimulator of chondrogenesis 1 -0.0058175
RTN1 reticulon 1 -0.00581723
CYB561 cytochrome b561 -0.00581317
GAS1 growth arrest-specific 1 -0.00580983
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa -0.00580429
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 -0.00580012
APOA2 apolipoprotein A-II -0.00579449
GPX1 glutathione peroxidase 1 -0.00577963
EIF3E eukaryotic translation initiation factor 3, subunit E -0.00576792
SCNN1A sodium channel, non voltage gated 1 alpha subunit -0.00575111
FGB fibrinogen beta chain -0.00573023
LGALS9 lectin, galactoside-binding, soluble, 9 -0.00572101
SFTPB surfactant protein B -0.00570018
MSX1 msh homeobox 1 -0.0056966
FLI1 Fli-1 proto-oncogene, ETS transcription factor -0.00569036
MB myoglobin -0.00567472
AFP alpha-fetoprotein -0.00566621
TMEM231 transmembrane protein 231 -0.00566582
DPYD dihydropyrimidine dehydrogenase -0.00566355
PTGIS prostaglandin I2 (prostacyclin) synthase -0.00565386
KLHL41 kelch-like family member 41 -0.0056534
TIPRL TOR signaling pathway regulator -0.0056428
TACSTD2 tumor-associated calcium signal transducer 2 -0.00563566
NCKAP1L NCK-associated protein 1-like -0.00562469
RRAS related RAS viral (r-ras) oncogene homolog -0.0056238
H1-0 H1.0 linker histone -0.00561785
MME membrane metallo-endopeptidase -0.00561003
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -0.00560436
FNTA farnesyltransferase, CAAX box, alpha -0.00559243
SMPX small muscle protein, X-linked -0.00557781
PXMP2 peroxisomal membrane protein 2, 22kDa -0.00556739
DDHD2 DDHD domain containing 2 -0.00556532
HLA-B major histocompatibility complex, class I, B -0.00556099
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae) -0.00554628
PMEPA1 prostate transmembrane protein, androgen induced 1 -0.00553179
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like -0.00551867
CRYL1 crystallin, lambda 1 -0.00551799
SNX17 sorting nexin 17 -0.00550718
LGMN legumain -0.00549604
SH3BGR SH3 domain binding glutamate-rich protein -0.00549525
DHRS7 dehydrogenase/reductase (SDR family) member 7 -0.00548082
MYL2 myosin, light chain 2, regulatory, cardiac, slow -0.00546501
VTCN1 V-set domain containing T cell activation inhibitor 1 -0.00545545
FAM216A family with sequence similarity 216, member A -0.0054463
KLHDC3 kelch domain containing 3 -0.00544345
C1R complement component 1, r subcomponent -0.00544014
GSTA4 glutathione S-transferase alpha 4 -0.00543806
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 -0.00543529
TPX2 TPX2, microtubule-associated -0.00543391
SYNE3 spectrin repeat containing, nuclear envelope family member 3 -0.00543026
APOC2 apolipoprotein C-II -0.00542896
CX3CR1 chemokine (C-X3-C motif) receptor 1 -0.00542847
SUB1 SUB1 homolog (S. cerevisiae) -0.00542332
LCP1 lymphocyte cytosolic protein 1 (L-plastin) -0.00542328
ACTG2 actin, gamma 2, smooth muscle, enteric -0.00542286
SQLE squalene epoxidase -0.00539693
PMP2 peripheral myelin protein 2 -0.00539261
KRT14 keratin 14, type I -0.00539067
MYO5C myosin VC -0.00539055
PNMA2 paraneoplastic Ma antigen 2 -0.00538577
OXTR oxytocin receptor -0.00536804
PRR7 proline rich 7 (synaptic) -0.00536691
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 -0.00534633
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 -0.00534572
CA3 carbonic anhydrase III -0.00533619
NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa -0.005325
RAB22A RAB22A, member RAS oncogene family -0.00531857
MRPL23 mitochondrial ribosomal protein L23 -0.0053165
CLEC7A C-type lectin domain family 7, member A -0.00531379
IL27RA interleukin 27 receptor, alpha -0.00531123