| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | rhodopsin|Retinitis pigmentosa is an inherited progressive disease which is a major cause of blindness in western communities. It can be inherited as an autosomal dominant, autosomal recessive, or X-linked recessive disorder. In the autosomal dominant form,which comprises about 25% of total cases, approximately 30% of families have mutations in the gene encoding the rod photoreceptor-specific protein rhodopsin. This is the transmembrane protein which, when photoexcited, initiates the visual transduction cascade. Defects in this gene are also one of the causes of congenital stationary night blindness. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6010) |
| External Link | https://ncbi.nlm.nih.gov/gene/6010 |
| Similar Terms | |
| Downloads & Tools |
498 genes differentially expressed following the RHO gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CA2 | carbonic anhydrase II | 0.0157841 |
| XIC | X chromosome inactivation center | 0.012886 |
| PCNA | proliferating cell nuclear antigen | 0.0125572 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | 0.0120425 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.0118832 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | 0.0116818 |
| HIST1H2BD | histone cluster 1, H2bd | 0.0113919 |
| PLIN2 | perilipin 2 | 0.0112007 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0111141 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.0109119 |
| GOLM1 | golgi membrane protein 1 | 0.0108329 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0108272 |
| CTSA | cathepsin A | 0.0107975 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.0107029 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | 0.010679 |
| PDE8A | phosphodiesterase 8A | 0.0105987 |
| DUSP5 | dual specificity phosphatase 5 | 0.010539 |
| TPBG | trophoblast glycoprotein | 0.0104189 |
| EZR | ezrin | 0.010297 |
| TFF1 | trefoil factor 1 | 0.0102555 |
| MMP3 | matrix metallopeptidase 3 | 0.0102059 |
| HEPH | hephaestin | 0.0101508 |
| CA12 | carbonic anhydrase XII | 0.0101239 |
| SLC25A46 | solute carrier family 25, member 46 | 0.0100687 |
| HIST1H2AC | histone cluster 1, H2ac | 0.0100419 |
| REG1A | regenerating islet-derived 1 alpha | 0.00990779 |
| CREM | cAMP responsive element modulator | 0.00989668 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa | 0.00980283 |
| EGR1 | early growth response 1 | 0.0097915 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.00964569 |
| HSPB8 | heat shock 22kDa protein 8 | 0.00957384 |
| GALC | galactosylceramidase | 0.00952451 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.00950269 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.00947917 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.00937007 |
| HIST1H2BK | histone cluster 1, H2bk | 0.00921296 |
| GATA6 | GATA binding protein 6 | 0.00897797 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00892872 |
| CTBP2 | C-terminal binding protein 2 | 0.00889291 |
| TTC39A | tetratricopeptide repeat domain 39A | 0.00886738 |
| SOCS1 | suppressor of cytokine signaling 1 | 0.00885407 |
| ADM | adrenomedullin | 0.00883394 |
| WFDC1 | WAP four-disulfide core domain 1 | 0.00882428 |
| STX3 | syntaxin 3 | 0.00867158 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0085899 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | 0.0085249 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.00851192 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.00842523 |
| FKBP4 | FK506 binding protein 4, 59kDa | 0.00838858 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.00838363 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00828891 |
| RASIP1 | Ras interacting protein 1 | 0.00828042 |
| RHOB | ras homolog family member B | 0.00827259 |
| EVI2A | ecotropic viral integration site 2A | 0.00824691 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.00822427 |
| TXNDC9 | thioredoxin domain containing 9 | 0.00818782 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | 0.00818421 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.00817545 |
| ADIRF | adipogenesis regulatory factor | 0.00815909 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | 0.00814144 |
| HIST1H2BH | histone cluster 1, H2bh | 0.00810731 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.00804962 |
| FA2H | fatty acid 2-hydroxylase | 0.00803003 |
| IRF9 | interferon regulatory factor 9 | 0.00792517 |
| ADCY9 | adenylate cyclase 9 | 0.00788654 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0078808 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.00780907 |
| GAB2 | GRB2-associated binding protein 2 | 0.0077634 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.00763327 |
| UPP1 | uridine phosphorylase 1 | 0.00762653 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.00761822 |
| SMAD3 | SMAD family member 3 | 0.00759466 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | 0.00757203 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.00756864 |
| CTSL | cathepsin L | 0.00755648 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | 0.00753398 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | 0.00753099 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.00753097 |
| RHOF | ras homolog family member F (in filopodia) | 0.00751038 |
| HIST1H2AE | histone cluster 1, H2ae | 0.00748321 |
| COL11A1 | collagen, type XI, alpha 1 | 0.00745736 |
| TBX3 | T-box 3 | 0.00742178 |
| FAM13B | family with sequence similarity 13, member B | 0.0073951 |
| TOB1 | transducer of ERBB2, 1 | 0.00738632 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | 0.00737718 |
| GPR137B | G protein-coupled receptor 137B | 0.00736417 |
| TUFT1 | tuftelin 1 | 0.00736049 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.00732193 |
| SDC4 | syndecan 4 | 0.00727855 |
| STC1 | stanniocalcin 1 | 0.00727105 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 | 0.00722694 |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 | 0.007186 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 0.00715932 |
| CYTIP | cytohesin 1 interacting protein | 0.00715508 |
| KCTD5 | potassium channel tetramerization domain containing 5 | 0.00714709 |
| LITAF | lipopolysaccharide-induced TNF factor | 0.00712336 |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A | 0.00711147 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.00710788 |
| MYRF | myelin regulatory factor | 0.00709691 |
| MAP7 | microtubule-associated protein 7 | 0.00708571 |
| RAB9A | RAB9A, member RAS oncogene family | 0.00707676 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 0.00701228 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.00694931 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.00694632 |
| CCNG2 | cyclin G2 | 0.00692526 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.00689822 |
| TRIB3 | tribbles pseudokinase 3 | 0.00687327 |
| RRAGC | Ras-related GTP binding C | 0.0068479 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.00678571 |
| POF1B | premature ovarian failure, 1B | 0.00678552 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00677925 |
| IL1R2 | interleukin 1 receptor, type II | 0.0067777 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.0067746 |
| MGLL | monoglyceride lipase | 0.00676619 |
| MRPL18 | mitochondrial ribosomal protein L18 | 0.00674533 |
| LOXL2 | lysyl oxidase-like 2 | 0.00672687 |
| TFF3 | trefoil factor 3 (intestinal) | 0.00671736 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.00671136 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.00670585 |
| CHN1 | chimerin 1 | 0.00669141 |
| ASS1 | argininosuccinate synthase 1 | 0.00668971 |
| DUSP1 | dual specificity phosphatase 1 | 0.00667201 |
| RGS13 | regulator of G-protein signaling 13 | 0.00664646 |
| COL15A1 | collagen, type XV, alpha 1 | 0.00664144 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.00661019 |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | 0.00660974 |
| H1-2 | H1.2 linker histone, cluster member | 0.00660391 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.0065869 |
| STC2 | stanniocalcin 2 | 0.00658677 |
| SQSTM1 | sequestosome 1 | 0.00657971 |
| GLA | galactosidase, alpha | 0.00657386 |
| MPO | myeloperoxidase | 0.00655129 |
| MPDZ | multiple PDZ domain protein | 0.00654129 |
| BICC1 | BicC family RNA binding protein 1 | 0.00651445 |
| SPAG9 | sperm associated antigen 9 | 0.00648383 |
| PDE2A | phosphodiesterase 2A, cGMP-stimulated | 0.00646866 |
| OGA | O-GlcNAcase | 0.00644559 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.00643604 |
| IL6 | interleukin 6 | 0.00643125 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | 0.00640205 |
| FNDC3A | fibronectin type III domain containing 3A | 0.00640093 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.006397 |
| IL7R | interleukin 7 receptor | 0.00638031 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.00636148 |
| RTN2 | reticulon 2 | 0.00633257 |
| RAB8A | RAB8A, member RAS oncogene family | 0.00632942 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.00631017 |
| ZG16 | zymogen granule protein 16 | 0.00630409 |
| SS18 | synovial sarcoma translocation, chromosome 18 | 0.00630099 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | 0.00629116 |
| PHIP | pleckstrin homology domain interacting protein | 0.00628791 |
| CEP170 | centrosomal protein 170kDa | 0.00628308 |
| PCDH17 | protocadherin 17 | 0.00626353 |
| PPP4R3A | protein phosphatase 4 regulatory subunit 3A | 0.00625597 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.00625431 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.00624563 |
| TPD52L1 | tumor protein D52-like 1 | 0.00621499 |
| HK2 | hexokinase 2 | 0.00621316 |
| MFSD1 | major facilitator superfamily domain containing 1 | 0.00620796 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.00620774 |
| TMEM127 | transmembrane protein 127 | 0.0061991 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.00619841 |
| SLC16A6 | solute carrier family 16, member 6 | 0.00618361 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.00617839 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | 0.00617434 |
| CLC | Charcot-Leyden crystal galectin | 0.00616956 |
| PFKP | phosphofructokinase, platelet | 0.0061565 |
| PTEN | phosphatase and tensin homolog | 0.00613645 |
| WIPF1 | WAS/WASL interacting protein family, member 1 | 0.00613496 |
| HMOX1 | heme oxygenase 1 | 0.00612205 |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 | 0.0061175 |
| ATG2A | autophagy related 2A | 0.00611072 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.00609451 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.00609272 |
| ACKR3 | atypical chemokine receptor 3 | 0.00607817 |
| GOLGA8A | golgin A8 family, member A | 0.00607218 |
| PAX5 | paired box 5 | 0.00606982 |
| WLS | wntless Wnt ligand secretion mediator | 0.00605266 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | 0.00605102 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 | 0.00603151 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | 0.0060208 |
| WASHC4 | WASH complex subunit 4 | 0.00600924 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 | 0.00600719 |
| VNN1 | vanin 1 | 0.00598674 |
| PFDN4 | prefoldin subunit 4 | 0.00597606 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | 0.00595082 |
| GNS | glucosamine (N-acetyl)-6-sulfatase | 0.00594469 |
| DUOX2 | dual oxidase 2 | 0.00593891 |
| CD22 | CD22 molecule | 0.00593827 |
| PHACTR2 | phosphatase and actin regulator 2 | 0.00593603 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa | 0.00593093 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.00592963 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.00592628 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | 0.00592201 |
| MCL1 | myeloid cell leukemia 1 | 0.00591313 |
| CCL4 | chemokine (C-C motif) ligand 4 | 0.00589954 |
| FOSL2 | FOS-like antigen 2 | 0.00589186 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | 0.00587181 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.00586924 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00586391 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.00586362 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | 0.00586031 |
| PILRB | paired immunoglobin-like type 2 receptor beta | 0.00582934 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.00582835 |
| NDNF | neuron-derived neurotrophic factor | 0.00582407 |
| TMEM131 | transmembrane protein 131 | 0.00582261 |
| TOX3 | TOX high mobility group box family member 3 | 0.00580075 |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 | 0.00579109 |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 | 0.00577632 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0057279 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.00572744 |
| G0S2 | G0/G1 switch 2 | 0.00572533 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.00572424 |
| AFF1 | AF4/FMR2 family, member 1 | 0.00572189 |
| CCDC68 | coiled-coil domain containing 68 | 0.00570754 |
| RIN2 | Ras and Rab interactor 2 | 0.00570545 |
| C21ORF91 | chromosome 21 open reading frame 91 | 0.00569244 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 0.00568215 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.00567959 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.00566351 |
| CCP110 | centriolar coiled coil protein 110kDa | 0.00566294 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.00565628 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.00564527 |
| NOTCH2 | notch 2 | 0.00564445 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.00564235 |
| SNX13 | sorting nexin 13 | 0.00563826 |
| TARP | TCR gamma alternate reading frame protein | 0.0056307 |
| FGF2 | fibroblast growth factor 2 (basic) | 0.00562394 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.00562268 |
| VEGFC | vascular endothelial growth factor C | 0.00562186 |
| XBP1 | X-box binding protein 1 | 0.00561665 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.00560878 |
| MID1IP1 | MID1 interacting protein 1 | 0.00560831 |
| ELANE | elastase, neutrophil expressed | 0.00560257 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 | 0.00558851 |
| HOXB6 | homeobox B6 | 0.00557985 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0055777 |
| MMD | monocyte to macrophage differentiation-associated | 0.00556244 |
| SCARB2 | scavenger receptor class B, member 2 | 0.00556225 |
| FOXF1 | forkhead box F1 | 0.00555989 |
| CCNA2 | cyclin A2 | 0.00555555 |
| CLCA4 | chloride channel accessory 4 | 0.00554964 |
| PIP4K2C | phosphatidylinositol-5-phosphate 4-kinase, type II, gamma | 0.00554578 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0055452 |
| CFD | complement factor D (adipsin) | 0.00553367 |
| RIT1 | Ras-like without CAAX 1 | 0.00553024 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 | 0.00552817 |
| SLC35D1 | solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 | 0.00551445 |
| STK10 | serine/threonine kinase 10 | 0.00551385 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GNAS | GNAS complex locus | -0.0219983 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0178174 |
| NRN1 | neuritin 1 | -0.0157059 |
| C3 | complement component 3 | -0.0135601 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.0135198 |
| MMP7 | matrix metallopeptidase 7 | -0.0132264 |
| MGP | matrix Gla protein | -0.0128019 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.0126838 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.0126432 |
| CP | ceruloplasmin (ferroxidase) | -0.0121353 |
| LTF | lactotransferrin | -0.0119549 |
| FGG | fibrinogen gamma chain | -0.0119293 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.011426 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.0113518 |
| FOXG1 | forkhead box G1 | -0.0111883 |
| NPY | neuropeptide Y | -0.0110944 |
| SOX11 | SRY (sex determining region Y)-box 11 | -0.0110719 |
| MYBPC1 | myosin binding protein C, slow type | -0.0107038 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.0106102 |
| RGCC | regulator of cell cycle | -0.0105902 |
| MUC16 | mucin 16, cell surface associated | -0.0105644 |
| MAGED1 | melanoma antigen family D1 | -0.0103602 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0102729 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0101563 |
| MSLN | mesothelin | -0.0101008 |
| TNNC1 | troponin C type 1 (slow) | -0.00987929 |
| FABP7 | fatty acid binding protein 7, brain | -0.0098778 |
| KRT5 | keratin 5, type II | -0.00973901 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00956431 |
| PADI2 | peptidyl arginine deiminase, type II | -0.00940496 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00919908 |
| FMO2 | flavin containing monooxygenase 2 (non-functional) | -0.00918941 |
| A2M | alpha-2-macroglobulin | -0.00913626 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.00911482 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | -0.00910355 |
| S100A2 | S100 calcium binding protein A2 | -0.00900209 |
| ALB | albumin | -0.008836 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.00873922 |
| MLF1 | myeloid leukemia factor 1 | -0.00856194 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | -0.0085271 |
| CD14 | CD14 molecule | -0.00851491 |
| C1RL | complement component 1, r subcomponent-like | -0.00850672 |
| YBX3 | Y box binding protein 3 | -0.00846047 |
| VSIG4 | V-set and immunoglobulin domain containing 4 | -0.008459 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | -0.00845216 |
| TUBA1A | tubulin, alpha 1a | -0.00845111 |
| SRPX | sushi-repeat containing protein, X-linked | -0.00841008 |
| BAD | BCL2-associated agonist of cell death | -0.00830319 |
| BIRC5 | baculoviral IAP repeat containing 5 | -0.00826687 |
| EMX2 | empty spiracles homeobox 2 | -0.00816089 |
| ACP6 | acid phosphatase 6, lysophosphatidic | -0.00815894 |
| PUF60 | poly-U binding splicing factor 60KDa | -0.00814249 |
| ADD3 | adducin 3 (gamma) | -0.00803433 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | -0.00802945 |
| PRMT1 | protein arginine methyltransferase 1 | -0.00800556 |
| KRT19 | keratin 19, type I | -0.00795594 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.00789474 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -0.00787856 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | -0.00787754 |
| THYN1 | thymocyte nuclear protein 1 | -0.00787035 |
| HAMP | hepcidin antimicrobial peptide | -0.00784982 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 | -0.00783841 |
| KRT7 | keratin 7, type II | -0.00782121 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | -0.00781281 |
| SIRT3 | sirtuin 3 | -0.00775608 |
| S100A8 | S100 calcium binding protein A8 | -0.0077323 |
| MOXD1 | monooxygenase, DBH-like 1 | -0.00766542 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.00763617 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.00756345 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -0.00756011 |
| CD59 | CD59 molecule, complement regulatory protein | -0.00754419 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.00751845 |
| MEOX2 | mesenchyme homeobox 2 | -0.00749477 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.00738083 |
| PRKCA | protein kinase C, alpha | -0.00737851 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.00733719 |
| RXYLT1 | ribitol xylosyltransferase 1 | -0.0073217 |
| BCHE | butyrylcholinesterase | -0.00730635 |
| COPS7A | COP9 signalosome subunit 7A | -0.00728723 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | -0.007285 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | -0.00726289 |
| MRPL12 | mitochondrial ribosomal protein L12 | -0.0072408 |
| H1-10 | H1.10 linker histone | -0.00722416 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.00717217 |
| NDRG2 | NDRG family member 2 | -0.00714275 |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha | -0.00713381 |
| EPAS1 | endothelial PAS domain protein 1 | -0.007132 |
| MYH10 | myosin, heavy chain 10, non-muscle | -0.00709998 |
| UBE2S | ubiquitin-conjugating enzyme E2S | -0.00707947 |
| GIMAP6 | GTPase, IMAP family member 6 | -0.00706316 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.00705639 |
| ASPN | asporin | -0.00698838 |
| ABHD2 | abhydrolase domain containing 2 | -0.00696806 |
| SELENOW | selenoprotein W | -0.00696412 |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 | -0.00695182 |
| SIVA1 | SIVA1, apoptosis-inducing factor | -0.00694227 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.00691689 |
| MIA | melanoma inhibitory activity | -0.00689969 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.0068793 |
| PALMD | palmdelphin | -0.00684545 |
| PWP1 | PWP1 homolog (S. cerevisiae) | -0.00684299 |
| C10ORF10 | chromosome 10 open reading frame 10 | -0.00684234 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.0068244 |
| E2F2 | E2F transcription factor 2 | -0.0068231 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 | -0.00681803 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 | -0.00677714 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.00674789 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -0.00674395 |
| PDLIM3 | PDZ and LIM domain 3 | -0.00673566 |
| APOD | apolipoprotein D | -0.00673395 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | -0.00671786 |
| AHCY | adenosylhomocysteinase | -0.0066829 |
| MPZL2 | myelin protein zero-like 2 | -0.00664199 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | -0.00662767 |
| BIN1 | bridging integrator 1 | -0.00662745 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | -0.00659272 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | -0.00658813 |
| COCH | cochlin | -0.00656086 |
| FOLR1 | folate receptor 1 (adult) | -0.00653221 |
| PTN | pleiotrophin | -0.00653037 |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 | -0.00646656 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | -0.00645089 |
| FAM3C | family with sequence similarity 3, member C | -0.00643737 |
| ADORA2B | adenosine A2b receptor | -0.00643532 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | -0.00642629 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.00641265 |
| CD320 | CD320 molecule | -0.00637493 |
| SLCO2B1 | solute carrier organic anion transporter family, member 2B1 | -0.00634596 |
| TMEM160 | transmembrane protein 160 | -0.00634018 |
| CPB2 | carboxypeptidase B2 (plasma) | -0.00633525 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.00631702 |
| LTA4H | leukotriene A4 hydrolase | -0.00631667 |
| DMAC2L | distal membrane arm assembly component 2 like | -0.00630951 |
| HMGB3 | high mobility group box 3 | -0.00630556 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | -0.00629656 |
| ODAM | odontogenic, ameloblast asssociated | -0.00629526 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 | -0.00628546 |
| APOA1 | apolipoprotein A-I | -0.00628326 |
| TNNI2 | troponin I type 2 (skeletal, fast) | -0.00627794 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -0.00626383 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.00626084 |
| PITX3 | paired-like homeodomain 3 | -0.00625944 |
| AQP4 | aquaporin 4 | -0.00625344 |
| PLK1 | polo-like kinase 1 | -0.00622072 |
| WDR61 | WD repeat domain 61 | -0.00620851 |
| AKAP7 | A kinase (PRKA) anchor protein 7 | -0.00620281 |
| RPIA | ribose 5-phosphate isomerase A | -0.00620003 |
| ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 | -0.00619534 |
| AKR1A1 | aldo-keto reductase family 1, member A1 (aldehyde reductase) | -0.00617812 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | -0.00617144 |
| TM6SF1 | transmembrane 6 superfamily member 1 | -0.00613875 |
| AK4 | adenylate kinase 4 | -0.00609838 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0060853 |
| GYPC | glycophorin C (Gerbich blood group) | -0.00608466 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.0060822 |
| DOK5 | docking protein 5 | -0.0060795 |
| HOPX | HOP homeobox | -0.0060761 |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 | -0.0060676 |
| SFTPD | surfactant protein D | -0.00605632 |
| DCXR | dicarbonyl/L-xylulose reductase | -0.00602867 |
| KRT6A | keratin 6A, type II | -0.00602294 |
| RAB25 | RAB25, member RAS oncogene family | -0.0060082 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | -0.00600251 |
| EHBP1 | EH domain binding protein 1 | -0.00599491 |
| HP | haptoglobin | -0.0059834 |
| HPF1 | histone PARylation factor 1 | -0.00597438 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | -0.00596995 |
| MFAP5 | microfibrillar associated protein 5 | -0.00593303 |
| ASRGL1 | asparaginase like 1 | -0.00592318 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | -0.00592253 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.00589294 |
| LAPTM5 | lysosomal protein transmembrane 5 | -0.00588335 |
| APOB | apolipoprotein B | -0.00588314 |
| CHI3L2 | chitinase 3-like 2 | -0.00587964 |
| CDC20 | cell division cycle 20 | -0.00587534 |
| USP13 | ubiquitin specific peptidase 13 (isopeptidase T-3) | -0.00587447 |
| TPM3 | tropomyosin 3 | -0.00587269 |
| CPVL | carboxypeptidase, vitellogenic-like | -0.00586244 |
| APOH | apolipoprotein H (beta-2-glycoprotein I) | -0.00583498 |
| SCRG1 | stimulator of chondrogenesis 1 | -0.0058175 |
| RTN1 | reticulon 1 | -0.00581723 |
| CYB561 | cytochrome b561 | -0.00581317 |
| GAS1 | growth arrest-specific 1 | -0.00580983 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | -0.00580429 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.00580012 |
| APOA2 | apolipoprotein A-II | -0.00579449 |
| GPX1 | glutathione peroxidase 1 | -0.00577963 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.00576792 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | -0.00575111 |
| FGB | fibrinogen beta chain | -0.00573023 |
| LGALS9 | lectin, galactoside-binding, soluble, 9 | -0.00572101 |
| SFTPB | surfactant protein B | -0.00570018 |
| MSX1 | msh homeobox 1 | -0.0056966 |
| FLI1 | Fli-1 proto-oncogene, ETS transcription factor | -0.00569036 |
| MB | myoglobin | -0.00567472 |
| AFP | alpha-fetoprotein | -0.00566621 |
| TMEM231 | transmembrane protein 231 | -0.00566582 |
| DPYD | dihydropyrimidine dehydrogenase | -0.00566355 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.00565386 |
| KLHL41 | kelch-like family member 41 | -0.0056534 |
| TIPRL | TOR signaling pathway regulator | -0.0056428 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00563566 |
| NCKAP1L | NCK-associated protein 1-like | -0.00562469 |
| RRAS | related RAS viral (r-ras) oncogene homolog | -0.0056238 |
| H1-0 | H1.0 linker histone | -0.00561785 |
| MME | membrane metallo-endopeptidase | -0.00561003 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | -0.00560436 |
| FNTA | farnesyltransferase, CAAX box, alpha | -0.00559243 |
| SMPX | small muscle protein, X-linked | -0.00557781 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | -0.00556739 |
| DDHD2 | DDHD domain containing 2 | -0.00556532 |
| HLA-B | major histocompatibility complex, class I, B | -0.00556099 |
| NPRL2 | nitrogen permease regulator-like 2 (S. cerevisiae) | -0.00554628 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.00553179 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | -0.00551867 |
| CRYL1 | crystallin, lambda 1 | -0.00551799 |
| SNX17 | sorting nexin 17 | -0.00550718 |
| LGMN | legumain | -0.00549604 |
| SH3BGR | SH3 domain binding glutamate-rich protein | -0.00549525 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -0.00548082 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | -0.00546501 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | -0.00545545 |
| FAM216A | family with sequence similarity 216, member A | -0.0054463 |
| KLHDC3 | kelch domain containing 3 | -0.00544345 |
| C1R | complement component 1, r subcomponent | -0.00544014 |
| GSTA4 | glutathione S-transferase alpha 4 | -0.00543806 |
| APPL1 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 | -0.00543529 |
| TPX2 | TPX2, microtubule-associated | -0.00543391 |
| SYNE3 | spectrin repeat containing, nuclear envelope family member 3 | -0.00543026 |
| APOC2 | apolipoprotein C-II | -0.00542896 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -0.00542847 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.00542332 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.00542328 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | -0.00542286 |
| SQLE | squalene epoxidase | -0.00539693 |
| PMP2 | peripheral myelin protein 2 | -0.00539261 |
| KRT14 | keratin 14, type I | -0.00539067 |
| MYO5C | myosin VC | -0.00539055 |
| PNMA2 | paraneoplastic Ma antigen 2 | -0.00538577 |
| OXTR | oxytocin receptor | -0.00536804 |
| PRR7 | proline rich 7 (synaptic) | -0.00536691 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 | -0.00534633 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 | -0.00534572 |
| CA3 | carbonic anhydrase III | -0.00533619 |
| NDUFA9 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa | -0.005325 |
| RAB22A | RAB22A, member RAS oncogene family | -0.00531857 |
| MRPL23 | mitochondrial ribosomal protein L23 | -0.0053165 |
| CLEC7A | C-type lectin domain family 7, member A | -0.00531379 |
| IL27RA | interleukin 27 receptor, alpha | -0.00531123 |