RHOA GTPase cycle Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-8980692
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Genes

149 proteins participating in the RHOA GTPase cycle pathway from the Reactome Pathways 2024 dataset.

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3
ABR active BCR-related
ACBD5 acyl-CoA binding domain containing 5
ACTC1 actin, alpha, cardiac muscle 1
AKAP13 A kinase (PRKA) anchor protein 13
ANLN anillin, actin binding protein
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARHGAP1 Rho GTPase activating protein 1
ARHGAP10 Rho GTPase activating protein 10
ARHGAP11A Rho GTPase activating protein 11A
ARHGAP11B Rho GTPase activating protein 11B
ARHGAP18 Rho GTPase activating protein 18
ARHGAP19 Rho GTPase activating protein 19
ARHGAP20 Rho GTPase activating protein 20
ARHGAP21 Rho GTPase activating protein 21
ARHGAP22 Rho GTPase activating protein 22
ARHGAP23 Rho GTPase activating protein 23
ARHGAP24 Rho GTPase activating protein 24
ARHGAP26 Rho GTPase activating protein 26
ARHGAP28 Rho GTPase activating protein 28
ARHGAP29 Rho GTPase activating protein 29
ARHGAP30 Rho GTPase activating protein 30
ARHGAP31 Rho GTPase activating protein 31
ARHGAP32 Rho GTPase activating protein 32
ARHGAP35 Rho GTPase activating protein 35
ARHGAP39 Rho GTPase activating protein 39
ARHGAP4 Rho GTPase activating protein 4
ARHGAP40 Rho GTPase activating protein 40
ARHGAP42 Rho GTPase activating protein 42
ARHGAP44 Rho GTPase activating protein 44
ARHGAP45 Rho GTPase activating protein 45
ARHGAP5 Rho GTPase activating protein 5
ARHGAP6 Rho GTPase activating protein 6
ARHGAP8 Rho GTPase activating protein 8
ARHGAP9 Rho GTPase activating protein 9
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18
ARHGEF19 Rho guanine nucleotide exchange factor (GEF) 19
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARHGEF25 Rho guanine nucleotide exchange factor (GEF) 25
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1
BCAP31 B-cell receptor-associated protein 31
BCR breakpoint cluster region
C1QBP complement component 1, q subcomponent binding protein
CAV1 caveolin 1, caveolae protein, 22kDa
CAVIN1 caveolae associated protein 1
CCDC115 coiled-coil domain containing 115
CIT citron rho-interacting serine/threonine kinase
DAAM1 dishevelled associated activator of morphogenesis 1
DDRGK1 DDRGK domain containing 1
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DEPDC1B DEP domain containing 1B
DIAPH1 diaphanous-related formin 1
DIAPH3 diaphanous-related formin 3
DLC1 DLC1 Rho GTPase activating protein
DOCK2 dedicator of cytokinesis 2
ECT2 epithelial cell transforming 2
EMC3 ER membrane protein complex subunit 3
ERBIN erbb2 interacting protein
FAF2 Fas associated factor family member 2
FAM13A family with sequence similarity 13, member A
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
FLOT1 flotillin 1
FLOT2 flotillin 2
FMNL3 formin-like 3
GMIP GEM interacting protein
HMOX2 heme oxygenase 2
IQGAP1 IQ motif containing GTPase activating protein 1
IQGAP3 IQ motif containing GTPase activating protein 3
JUP junction plakoglobin
KALRN kalirin, RhoGEF kinase
KTN1 kinectin 1 (kinesin receptor)
LBR lamin B receptor
LMAN1 lectin, mannose-binding, 1
MACO1 macoilin 1
MCAM melanoma cell adhesion molecule
MCF2 MCF.2 cell line derived transforming sequence
MCF2L MCF.2 cell line derived transforming sequence-like
MYO9A myosin IXA
MYO9B myosin IXB
NET1 neuroepithelial cell transforming 1
NGEF neuronal guanine nucleotide exchange factor
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OPHN1 oligophrenin 1
PCDH7 protocadherin 7
PGRMC2 progesterone receptor membrane component 2
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PKN1 protein kinase N1
PKN2 protein kinase N2
PKN3 protein kinase N3
PLD1 phospholipase D1, phosphatidylcholine-specific
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PLEKHG4 pleckstrin homology domain containing, family G (with RhoGef domain) member 4
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
RACGAP1 Rac GTPase activating protein 1
RASGRF2 Ras protein-specific guanine nucleotide-releasing factor 2
RHOA ras homolog family member A
RHPN1 rhophilin, Rho GTPase binding protein 1
RHPN2 rhophilin, Rho GTPase binding protein 2
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RTKN rhotekin
SCFD1 sec1 family domain containing 1
SLK STE20-like kinase
SNAP23 synaptosomal-associated protein, 23kDa
SOWAHC sosondowah ankyrin repeat domain family member C
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1
STARD13 StAR-related lipid transfer (START) domain containing 13
STARD8 StAR-related lipid transfer (START) domain containing 8
STBD1 starch binding domain 1
STK10 serine/threonine kinase 10
STOM stomatin
STX5 syntaxin 5
TAGAP T-cell activation RhoGTPase activating protein
TEX2 testis expressed 2
TFRC transferrin receptor
TIAM1 T-cell lymphoma invasion and metastasis 1
TJP2 tight junction protein 2
TMEM87A transmembrane protein 87A
TMPO thymopoietin
TRIO trio Rho guanine nucleotide exchange factor
VAMP3 vesicle-associated membrane protein 3
VANGL1 VANGL planar cell polarity protein 1
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C
VAV1 vav 1 guanine nucleotide exchange factor
VAV2 vav 2 guanine nucleotide exchange factor
VAV3 vav 3 guanine nucleotide exchange factor
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)