RHOBTB3 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description Rho-related BTB domain containing 3|RHOBTB3 is a member of the evolutionarily conserved RHOBTB subfamily of Rho GTPases. For background information on RHOBTBs, see RHOBTB1 (MIM 607351).[supplied by OMIM, Apr 2004] (NCBI Entrez Gene Database, 22836)
External Link https://ncbi.nlm.nih.gov/gene/22836
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Genes

499 genes differentially expressed following the RHOBTB3 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
LAMP5 lysosomal-associated membrane protein family, member 5 0.0131036
MGP matrix Gla protein 0.0130269
ESR1 estrogen receptor 1 0.0128574
PLK1 polo-like kinase 1 0.0124822
DACH1 dachshund family transcription factor 1 0.0119552
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 0.0109601
ZDHHC6 zinc finger, DHHC-type containing 6 0.010945
RGS5 regulator of G-protein signaling 5 0.0105471
C7 complement component 7 0.0104386
METTL7A methyltransferase like 7A 0.0101817
HELLS helicase, lymphoid-specific 0.0101091
TMSB15A thymosin beta 15a 0.0099582
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.00983687
PDLIM3 PDZ and LIM domain 3 0.00970128
AURKB aurora kinase B 0.00936388
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.00932403
SPC25 SPC25, NDC80 kinetochore complex component 0.00927836
SLIT2 slit homolog 2 (Drosophila) 0.00910916
NR2F6 nuclear receptor subfamily 2, group F, member 6 0.00904139
NR2F1 nuclear receptor subfamily 2, group F, member 1 0.0090084
FASN fatty acid synthase 0.00899683
PEG3 paternally expressed 3 0.00888635
ADGRF5 adhesion G protein-coupled receptor F5 0.00885085
KIF14 kinesin family member 14 0.00879047
ARHGAP29 Rho GTPase activating protein 29 0.00878361
UBE2S ubiquitin-conjugating enzyme E2S 0.00862035
BGN biglycan 0.00861284
DEGS1 delta(4)-desaturase, sphingolipid 1 0.00860863
GTSE1 G-2 and S-phase expressed 1 0.00855629
TM9SF3 transmembrane 9 superfamily member 3 0.00854071
FRZB frizzled-related protein 0.00849298
CHEK2 checkpoint kinase 2 0.00833764
NVL nuclear VCP-like 0.00832515
TSPAN12 tetraspanin 12 0.00831053
CPT1A carnitine palmitoyltransferase 1A (liver) 0.00818606
IGFBP5 insulin-like growth factor binding protein 5 0.00810008
MYO5C myosin VC 0.00802998
IGF1 insulin-like growth factor 1 (somatomedin C) 0.00797612
PIMREG PICALM interacting mitotic regulator 0.00797098
NDC80 NDC80 kinetochore complex component 0.00796016
OIP5 Opa interacting protein 5 0.00791823
COMP cartilage oligomeric matrix protein 0.00791313
KIF11 kinesin family member 11 0.00782934
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 0.00777639
CDC45 cell division cycle 45 0.00777575
PTGIS prostaglandin I2 (prostacyclin) synthase 0.0077094
PAH phenylalanine hydroxylase 0.00770718
INSIG1 insulin induced gene 1 0.00769671
FOXF1 forkhead box F1 0.00769243
RBBP8 retinoblastoma binding protein 8 0.00768012
SLC38A1 solute carrier family 38, member 1 0.00757734
SDC2 syndecan 2 0.00757352
TOP2A topoisomerase (DNA) II alpha 170kDa 0.00754358
PBK PDZ binding kinase 0.00754008
HMGB3 high mobility group box 3 0.00751506
CDCA3 cell division cycle associated 3 0.00749913
CALD1 caldesmon 1 0.00749212
TMEM176B transmembrane protein 176B 0.00748851
CCN2 cellular communication network factor 2 0.00748251
GINS1 GINS complex subunit 1 (Psf1 homolog) 0.00746088
AEBP1 AE binding protein 1 0.00745586
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 0.00739501
RAPSN receptor-associated protein of the synapse 0.00738034
CEP55 centrosomal protein 55kDa 0.0073558
SPARCL1 SPARC-like 1 (hevin) 0.00734724
HMGB2 high mobility group box 2 0.0073095
NEK2 NIMA-related kinase 2 0.00730477
BPHL biphenyl hydrolase-like (serine hydrolase) 0.00728716
CBX3 chromobox homolog 3 0.00727661
TMPO thymopoietin 0.00727337
MATN2 matrilin 2 0.00727283
CTBP2 C-terminal binding protein 2 0.00726458
CRLF1 cytokine receptor-like factor 1 0.007261
DPYSL2 dihydropyrimidinase-like 2 0.0072395
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.00721706
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.00720497
GPSM2 G-protein signaling modulator 2 0.00714281
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 0.00706008
IGFBP1 insulin-like growth factor binding protein 1 0.00698835
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 0.00697966
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.00697564
TUBA1A tubulin, alpha 1a 0.00696266
PLN phospholamban 0.00694673
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 0.00690533
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A 0.00687661
RUFY3 RUN and FYVE domain containing 3 0.00680216
TMEM204 transmembrane protein 204 0.0067922
SEPTIN10 septin 10 0.00676926
RPA3 replication protein A3, 14kDa 0.00674285
LIMCH1 LIM and calponin homology domains 1 0.00673711
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.00672191
SPAG5 sperm associated antigen 5 0.00671436
CRABP2 cellular retinoic acid binding protein 2 0.00670157
FXYD6 FXYD domain containing ion transport regulator 6 0.00667231
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 0.0066669
SQLE squalene epoxidase 0.00666257
BUB3 BUB3 mitotic checkpoint protein 0.00662665
ALB albumin 0.00660521
RAD51AP1 RAD51 associated protein 1 0.006593
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) 0.00658343
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E 0.00656479
NUSAP1 nucleolar and spindle associated protein 1 0.00655303
EFHD1 EF-hand domain family, member D1 0.00653324
LYZ lysozyme 0.00652914
EPCAM epithelial cell adhesion molecule 0.0065044
ARID4A AT rich interactive domain 4A (RBP1-like) 0.00648634
ISYNA1 inositol-3-phosphate synthase 1 0.00648327
ENOPH1 enolase-phosphatase 1 0.00647877
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 0.00647582
GATA6 GATA binding protein 6 0.00646917
KIF20A kinesin family member 20A 0.00646295
FBXO21 F-box protein 21 0.00645677
TIMP3 TIMP metallopeptidase inhibitor 3 0.00645485
F2R coagulation factor II (thrombin) receptor 0.00645052
MMP2 matrix metallopeptidase 2 0.00643553
BCHE butyrylcholinesterase 0.00642467
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.00641229
KIFC1 kinesin family member C1 0.00638209
SEC23A Sec23 homolog A (S. cerevisiae) 0.0063793
SLC2A4RG SLC2A4 regulator 0.0063722
PALLD palladin, cytoskeletal associated protein 0.0063713
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 0.00637121
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 0.00634968
KLHL23 kelch-like family member 23 0.00634606
ABHD2 abhydrolase domain containing 2 0.00633669
KRT19 keratin 19, type I 0.00631266
HMGN5 high mobility group nucleosome binding domain 5 0.00629779
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.00629446
TCF21 transcription factor 21 0.00627143
ARMT1 acidic residue methyltransferase 1 0.00625458
SHTN1 shootin 1 0.00624255
KLHDC3 kelch domain containing 3 0.00623682
PGAM1 phosphoglycerate mutase 1 (brain) 0.0062296
NRGN neurogranin (protein kinase C substrate, RC3) 0.00621528
SIRT3 sirtuin 3 0.00621341
C20ORF27 chromosome 20 open reading frame 27 0.00621218
COL10A1 collagen, type X, alpha 1 0.0061764
ASPN asporin 0.00617248
DHFR dihydrofolate reductase 0.00617076
CFH complement factor H 0.0061669
COL3A1 collagen, type III, alpha 1 0.00615843
NSD2 nuclear receptor binding SET domain protein 2 0.00615223
ISOC1 isochorismatase domain containing 1 0.00615143
BARD1 BRCA1 associated RING domain 1 0.0061497
CENPF centromere protein F, 350/400kDa 0.00613365
BIRC5 baculoviral IAP repeat containing 5 0.00612915
ASRGL1 asparaginase like 1 0.00612013
TMEM106C transmembrane protein 106C 0.00610741
LPCAT1 lysophosphatidylcholine acyltransferase 1 0.00609837
NTAN1 N-terminal asparagine amidase 0.00609549
HIP1 huntingtin interacting protein 1 0.00608999
HOXB6 homeobox B6 0.00608737
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 0.00608737
MBL2 mannose-binding lectin (protein C) 2, soluble 0.0060795
PMM2 phosphomannomutase 2 0.00607769
CFI complement factor I 0.00606524
DCXR dicarbonyl/L-xylulose reductase 0.00605524
SRP9 signal recognition particle 9kDa 0.00605484
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 0.00604062
COLEC11 collectin sub-family member 11 0.00603686
MTERF3 mitochondrial transcription termination factor 3 0.0060343
CDC20 cell division cycle 20 0.0060227
RCN2 reticulocalbin 2, EF-hand calcium binding domain 0.0060198
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 0.00600411
AMBP alpha-1-microglobulin/bikunin precursor 0.00599244
DDHD2 DDHD domain containing 2 0.00598962
CCNA2 cyclin A2 0.00598482
BAD BCL2-associated agonist of cell death 0.00597456
RAMP1 receptor (G protein-coupled) activity modifying protein 1 0.00597169
TMEM14A transmembrane protein 14A 0.00596653
RAD21 RAD21 homolog (S. pombe) 0.00594087
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.00592776
EPHB2 EPH receptor B2 0.00592413
TNNT1 troponin T type 1 (skeletal, slow) 0.00591733
HEY2 hes-related family bHLH transcription factor with YRPW motif 2 0.00591471
ZNF423 zinc finger protein 423 0.0058924
MPHOSPH9 M-phase phosphoprotein 9 0.0058873
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.00588454
CDC7 cell division cycle 7 0.00588187
CXCL14 chemokine (C-X-C motif) ligand 14 0.00587914
NEIL3 nei endonuclease VIII-like 3 (E. coli) 0.00587406
GINS2 GINS complex subunit 2 (Psf2 homolog) 0.00586222
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 0.00585092
CBR3 carbonyl reductase 3 0.00583667
SPON2 spondin 2, extracellular matrix protein 0.00583285
CDC25C cell division cycle 25C 0.00582104
FBXO5 F-box protein 5 0.00581467
NPTX2 neuronal pentraxin II 0.00581062
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.00580382
LBR lamin B receptor 0.00579534
PRRC2A proline-rich coiled-coil 2A 0.0057952
PLAT plasminogen activator, tissue 0.00578558
CDC42 cell division cycle 42 0.00577511
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 0.00576529
TARDBP TAR DNA binding protein 0.00575787
GRB14 growth factor receptor-bound protein 14 0.00574221
NELL1 NEL-like 1 (chicken) 0.00574047
SFRP4 secreted frizzled-related protein 4 0.00573995
CD93 CD93 molecule 0.00573846
HPR haptoglobin-related protein 0.00573383
RAB20 RAB20, member RAS oncogene family 0.0057227
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 0.00571677
ESM1 endothelial cell-specific molecule 1 0.00570792
SRSF6 serine/arginine-rich splicing factor 6 0.00570252
CPB2 carboxypeptidase B2 (plasma) 0.00570231
VEGFA vascular endothelial growth factor A 0.00570117
PLPP3 phospholipid phosphatase 3 0.00569328
MKKS McKusick-Kaufman syndrome 0.00568629
LRRC17 leucine rich repeat containing 17 0.00567344
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 0.00566986
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.00566823
EVA1B eva-1 homolog B (C. elegans) 0.00566501
PARPBP PARP1 binding protein 0.00566489
GAS2 growth arrest-specific 2 0.00565174
TACC3 transforming, acidic coiled-coil containing protein 3 0.00564553
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.00563315
CIT citron rho-interacting serine/threonine kinase 0.00563099
NID1 nidogen 1 0.00561085
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 0.00560272
PRDX3 peroxiredoxin 3 0.00560175
DEK DEK proto-oncogene 0.00559262
REC8 REC8 meiotic recombination protein 0.00558554
FOXM1 forkhead box M1 0.00556338
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.00555428
HOXC6 homeobox C6 0.00554711
CDK1 cyclin-dependent kinase 1 0.00553696
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 0.00553465
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 0.0055279
ACAT2 acetyl-CoA acetyltransferase 2 0.00552726
ASF1B anti-silencing function 1B histone chaperone 0.00552706
FABP1 fatty acid binding protein 1, liver 0.00551682
VWA1 von Willebrand factor A domain containing 1 0.00551613
RMI1 RecQ mediated genome instability 1 0.00550651
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 0.00549463
MEIS2 Meis homeobox 2 0.00548081
RNASEH2A ribonuclease H2, subunit A 0.00548036
HMGB1 high mobility group box 1 0.00548009
HNMT histamine N-methyltransferase 0.00546998
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 0.0054674
ELOVL6 ELOVL fatty acid elongase 6 0.00546015
EXPH5 exophilin 5 0.00545867
TSEN34 TSEN34 tRNA splicing endonuclease subunit 0.00545157
ENPEP glutamyl aminopeptidase (aminopeptidase A) 0.00544801
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain 0.00544753
ADIRF adipogenesis regulatory factor 0.00543422
SHLD2 shieldin complex subunit 2 0.005432
COL6A2 collagen, type VI, alpha 2 0.00542987
SAC3D1 SAC3 domain containing 1 0.00542573
BZW1 basic leucine zipper and W2 domains 1 0.00542404
NUP37 nucleoporin 37kDa 0.00542339

decreased expression

Symbol Name Standardized Value
LTF lactotransferrin -0.0196163
S100A9 S100 calcium binding protein A9 -0.0191955
S100A8 S100 calcium binding protein A8 -0.0170276
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0166044
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) -0.0159229
KRT17 keratin 17, type I -0.014233
KRT6A keratin 6A, type II -0.0141175
SYNGR3 synaptogyrin 3 -0.0137797
TRIM29 tripartite motif containing 29 -0.0135289
KRT5 keratin 5, type II -0.0133549
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.0131434
CXCL8 chemokine (C-X-C motif) ligand 8 -0.0129819
SLPI secretory leukocyte peptidase inhibitor -0.0129135
FXYD3 FXYD domain containing ion transport regulator 3 -0.0129034
PI3 peptidase inhibitor 3, skin-derived -0.0128594
KRT14 keratin 14, type I -0.0127091
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -0.0124669
CSTA cystatin A (stefin A) -0.0120686
NIBAN1 niban apoptosis regulator 1 -0.0119534
PRAME preferentially expressed antigen in melanoma -0.0118676
FABP5 fatty acid binding protein 5 (psoriasis-associated) -0.0116701
SPRR1B small proline-rich protein 1B -0.0113732
FOSL2 FOS-like antigen 2 -0.0112961
RALB v-ral simian leukemia viral oncogene homolog B -0.0112589
IRS2 insulin receptor substrate 2 -0.0110628
CRYAB crystallin, alpha B -0.010996
ATF3 activating transcription factor 3 -0.0109027
S100A7 S100 calcium binding protein A7 -0.0108106
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.0106171
KRT15 keratin 15, type I -0.0105391
AQP3 aquaporin 3 (Gill blood group) -0.010419
MAGEA3 melanoma antigen family A3 -0.0102929
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.0102653
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.0102517
TENT5A terminal nucleotidyltransferase 5A -0.0101154
KYNU kynureninase -0.00998023
CST7 cystatin F (leukocystatin) -0.009796
ANXA1 annexin A1 -0.00975137
ISG20 interferon stimulated exonuclease gene 20kDa -0.00967097
CD59 CD59 molecule, complement regulatory protein -0.00961673
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.00958185
KRT6B keratin 6B, type II -0.0094631
BAMBI BMP and activin membrane-bound inhibitor -0.00937583
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.00923714
SAT1 spermidine/spermine N1-acetyltransferase 1 -0.00918458
IFI27 interferon, alpha-inducible protein 27 -0.00911592
RUNX3 runt-related transcription factor 3 -0.00903011
BASP1 brain abundant, membrane attached signal protein 1 -0.00901918
TARP TCR gamma alternate reading frame protein -0.00884861
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 -0.00881807
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 -0.00874524
IL1RN interleukin 1 receptor antagonist -0.00870672
EGR1 early growth response 1 -0.00869342
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 -0.00866872
IFI44L interferon-induced protein 44-like -0.00865556
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 -0.00860846
LBH limb bud and heart development -0.00853752
HMOX1 heme oxygenase 1 -0.00845958
FABP4 fatty acid binding protein 4, adipocyte -0.00844528
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha -0.00842062
PKP1 plakophilin 1 -0.00841636
SPTBN1 spectrin, beta, non-erythrocytic 1 -0.00817148
KRT7 keratin 7, type II -0.00812594
COCH cochlin -0.00812022
REEP5 receptor accessory protein 5 -0.0079772
CRISP3 cysteine-rich secretory protein 3 -0.00797591
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -0.00796847
ANO10 anoctamin 10 -0.00795018
MYBPC1 myosin binding protein C, slow type -0.00790088
TRIP6 thyroid hormone receptor interactor 6 -0.00787017
IL32 interleukin 32 -0.00782945
PITX3 paired-like homeodomain 3 -0.00780405
CLTB clathrin, light chain B -0.00779643
IL2RG interleukin 2 receptor, gamma -0.00776137
S100A12 S100 calcium binding protein A12 -0.00774825
GM2A GM2 ganglioside activator -0.00767901
HBD hemoglobin, delta -0.00761577
SPRR3 small proline-rich protein 3 -0.00755477
KRT13 keratin 13, type I -0.00755439
TFPI2 tissue factor pathway inhibitor 2 -0.00754189
IFITM1 interferon induced transmembrane protein 1 -0.00751701
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.00751083
GPNMB glycoprotein (transmembrane) nmb -0.00748224
SPRR1A small proline-rich protein 1A -0.00745837
SPRR2B small proline-rich protein 2B -0.00745391
MYO1C myosin IC -0.00741911
MMP8 matrix metallopeptidase 8 -0.00741786
RCAN1 regulator of calcineurin 1 -0.00740823
AQP1 aquaporin 1 (Colton blood group) -0.00740502
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -0.00739664
CA2 carbonic anhydrase II -0.00738249
CXCL5 chemokine (C-X-C motif) ligand 5 -0.00736513
PIP prolactin-induced protein -0.00732224
GJA1 gap junction protein, alpha 1, 43kDa -0.00729849
S100P S100 calcium binding protein P -0.00729647
TRIM22 tripartite motif containing 22 -0.0072842
PFKP phosphofructokinase, platelet -0.00726774
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 -0.00725976
TUFT1 tuftelin 1 -0.00723965
PDZK1IP1 PDZK1 interacting protein 1 -0.00722995
ANXA3 annexin A3 -0.00722904
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa -0.0072248
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) -0.0072197
BCL2A1 BCL2-related protein A1 -0.00721241
RPL36 ribosomal protein L36 -0.00720957
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type -0.00718951
GSTP1 glutathione S-transferase pi 1 -0.00714601
RRAGD Ras-related GTP binding D -0.00713305
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 -0.00713287
FKBP11 FK506 binding protein 11, 19 kDa -0.00712399
SP110 SP110 nuclear body protein -0.00710347
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 -0.00709935
UBE2L6 ubiquitin-conjugating enzyme E2L 6 -0.00708664
GABARAPL1 GABA(A) receptor-associated protein like 1 -0.00707663
TM4SF1 transmembrane 4 L six family member 1 -0.00707455
DDIT3 DNA-damage-inducible transcript 3 -0.00705997
LAMP3 lysosomal-associated membrane protein 3 -0.00705743
JUNB jun B proto-oncogene -0.00702545
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.00700227
CD38 CD38 molecule -0.00700094
AHNAK2 AHNAK nucleoprotein 2 -0.00696988
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa -0.00695088
PRF1 perforin 1 (pore forming protein) -0.00694298
HIST1H2BD histone cluster 1, H2bd -0.00690958
PADI2 peptidyl arginine deiminase, type II -0.00690274
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 -0.00690156
MX1 MX dynamin-like GTPase 1 -0.00689118
RND3 Rho family GTPase 3 -0.00688929
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -0.00687826
GPM6B glycoprotein M6B -0.00685858
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -0.006847
RPS27L ribosomal protein S27-like -0.00681815
APOD apolipoprotein D -0.00678658
CPA3 carboxypeptidase A3 (mast cell) -0.0067808
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 -0.00676306
IRF1 interferon regulatory factor 1 -0.00674834
TMEM140 transmembrane protein 140 -0.00672078
TRIM16 tripartite motif containing 16 -0.00671682
TP63 tumor protein p63 -0.00669833
PARP12 poly (ADP-ribose) polymerase family, member 12 -0.00668303
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta -0.00667189
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) -0.00666493
MFAP3L microfibrillar-associated protein 3-like -0.00665663
LY75 lymphocyte antigen 75 -0.00665466
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 -0.00660874
CEBPB CCAAT/enhancer binding protein (C/EBP), beta -0.00659092
FOXD1 forkhead box D1 -0.00658817
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 -0.00656457
HK2 hexokinase 2 -0.00655119
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -0.00653359
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) -0.0065316
PPL periplakin -0.00651688
MT1X metallothionein 1X -0.00651604
PLAUR plasminogen activator, urokinase receptor -0.00647994
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -0.00647678
CAPN3 calpain 3, (p94) -0.0064441
CNOT4 CCR4-NOT transcription complex, subunit 4 -0.00643982
TPD52L1 tumor protein D52-like 1 -0.00642992
PRDX6 peroxiredoxin 6 -0.00642493
CREB3L1 cAMP responsive element binding protein 3-like 1 -0.00642398
JMJD6 jumonji domain containing 6 -0.00641983
BMP7 bone morphogenetic protein 7 -0.00640826
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -0.00639657
SLC35F2 solute carrier family 35, member F2 -0.00638941
TARBP1 TAR (HIV-1) RNA binding protein 1 -0.00638049
TMEM59 transmembrane protein 59 -0.006375
MAL mal, T-cell differentiation protein -0.00636501
OPTN optineurin -0.00635
CLCA4 chloride channel accessory 4 -0.0063414
RIPK2 receptor-interacting serine-threonine kinase 2 -0.00633633
SIK1 salt-inducible kinase 1 -0.00633264
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 -0.0063173
RAB6B RAB6B, member RAS oncogene family -0.00630855
FEM1C fem-1 homolog c (C. elegans) -0.00630118
GADD45A growth arrest and DNA-damage-inducible, alpha -0.00630007
VGLL4 vestigial-like family member 4 -0.00629797
PREPL prolyl endopeptidase-like -0.00628279
IER5 immediate early response 5 -0.00627619
ALOX5AP arachidonate 5-lipoxygenase-activating protein -0.00626714
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II -0.00626506
ITK IL2-inducible T-cell kinase -0.00626332
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 -0.00626197
SFN stratifin -0.00624953
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 -0.00623182
NUPR1 nuclear protein, transcriptional regulator, 1 -0.00623156
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 -0.00622305
SLC39A14 solute carrier family 39 (zinc transporter), member 14 -0.00622177
PARD3 par-3 family cell polarity regulator -0.00620481
GPI glucose-6-phosphate isomerase -0.0061539
BIRC3 baculoviral IAP repeat containing 3 -0.00614872
ELL2 elongation factor, RNA polymerase II, 2 -0.00614798
PLAGL1 pleiomorphic adenoma gene-like 1 -0.00614719
LGALS13 lectin, galactoside-binding, soluble, 13 -0.00613623
GPC4 glypican 4 -0.00612764
ADM adrenomedullin -0.00610415
HDDC2 HD domain containing 2 -0.00609436
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) -0.00608979
DEFA4 defensin, alpha 4, corticostatin -0.0060866
MSRB2 methionine sulfoxide reductase B2 -0.0060651
NAMPT nicotinamide phosphoribosyltransferase -0.00606229
MPO myeloperoxidase -0.00605142
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A -0.00602718
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 -0.00602037
KLK11 kallikrein-related peptidase 11 -0.00601714
LAMC2 laminin, gamma 2 -0.00601157
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) -0.00600854
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.00600516
RPS17 ribosomal protein S17 -0.00599323
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha -0.00598892
ZC3H12A zinc finger CCCH-type containing 12A -0.00598398
CLCA2 chloride channel accessory 2 -0.00597322
LYPD3 LY6/PLAUR domain containing 3 -0.00597303
PGAP3 post-GPI attachment to proteins 3 -0.00596763
STK38L serine/threonine kinase 38 like -0.00594194
S100A2 S100 calcium binding protein A2 -0.00593072
ABHD5 abhydrolase domain containing 5 -0.00592675
OXTR oxytocin receptor -0.00591946
TGFA transforming growth factor, alpha -0.00591874
STATH statherin -0.00591703
FOLR1 folate receptor 1 (adult) -0.00591699
KRT16 keratin 16, type I -0.00591402
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -0.00590765
TFF1 trefoil factor 1 -0.00589262
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.00589124
GRAMD2B GRAM domain containing 2B -0.00588871
DEPTOR DEP domain containing MTOR-interacting protein -0.00588125
SH3GLB1 SH3-domain GRB2-like endophilin B1 -0.00586588
ZNHIT6 zinc finger, HIT-type containing 6 -0.00584677
CTSS cathepsin S -0.00583902
PRSS23 protease, serine, 23 -0.00582922
PPP1R15A protein phosphatase 1, regulatory subunit 15A -0.00582671
AREG amphiregulin -0.0058159
LARP6 La ribonucleoprotein domain family, member 6 -0.00581257
CTSG cathepsin G -0.00580519
ZIC1 Zic family member 1 -0.00580401
STOM stomatin -0.00580099
TACSTD2 tumor-associated calcium signal transducer 2 -0.00578509
TSLIG3A tRNA splicing ligase complex subunit 3A -0.00576757
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 -0.00576085
SNCA synuclein, alpha (non A4 component of amyloid precursor) -0.0057421
SOD2 superoxide dismutase 2, mitochondrial -0.00573349
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 -0.00572194
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 -0.00571687
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 -0.00571045
DSC2 desmocollin 2 -0.005691
TRIM38 tripartite motif containing 38 -0.00567536
PERP PERP, TP53 apoptosis effector -0.00566979
ISG15 ISG15 ubiquitin-like modifier -0.00565786
ATP5PD ATP synthase peripheral stalk subunit d -0.00564777