RHOD Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description ras homolog family member D|Ras homolog, or Rho, proteins interact with protein kinases and may serve as targets for activated GTPase. They play a critical role in muscle differentiation. The protein encoded by this gene binds GTP and is a member of the small GTPase superfamily. It is involved in endosome dynamics and reorganization of the actin cytoskeleton, and it may coordinate membrane transport with the function of the cytoskeleton. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014] (NCBI Entrez Gene Database, 29984)
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Genes

321 genes differentially expressed following the RHOD gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
NPIPB9 nuclear pore complex interacting protein family, member B9 2.93812
NTN5 netrin 5 2.93812
PCDHA1 protocadherin alpha 1 2.93812
CFAP61 cilia and flagella associated protein 61 2.93812
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 2.93812
CA9 carbonic anhydrase IX 2.93812
F11 coagulation factor XI 2.93812
SCN10A sodium channel, voltage gated, type X alpha subunit 2.93812
VWA5B2 von Willebrand factor A domain containing 5B2 2.93812
CXCL16 chemokine (C-X-C motif) ligand 16 2.93812
NAV1 neuron navigator 1 2.93812
FAM209A family with sequence similarity 209, member A 2.93812
NPPC natriuretic peptide C 2.93812
RASL10A RAS-like, family 10, member A 2.93812
MRLN myoregulin 2.93812
PCDHGA3 protocadherin gamma subfamily A, 3 2.93812
ARHGAP20 Rho GTPase activating protein 20 2.93812
ZNF365 zinc finger protein 365 2.93812
ERVV-2 endogenous retrovirus group V, member 2 2.93812
CFHR3 complement factor H-related 3 2.93812
COX8C cytochrome c oxidase subunit VIIIC 2.93812
KLB klotho beta 2.93812
PPP1R3G protein phosphatase 1, regulatory subunit 3G 2.93812
OR1C1 olfactory receptor, family 1, subfamily C, member 1 2.93812
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 2.93812
DPEP2 dipeptidase 2 2.78096
MEI4 meiosis-specific 4 homolog (S. cerevisiae) 2.78096
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa 2.78096
MAP3K7CL MAP3K7 C-terminal like 2.78096
DNAJC5G DnaJ (Hsp40) homolog, subfamily C, member 5 gamma 2.78096
LRRD1 leucine-rich repeats and death domain containing 1 2.78096
EGFLAM EGF-like, fibronectin type III and laminin G domains 2.78096
HRH1 histamine receptor H1 2.78096
INHBB inhibin, beta B 2.78096
SIX2 SIX homeobox 2 2.78096
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A 2.78096
ACVRL1 activin A receptor type II-like 1 2.78096
F2 coagulation factor II (thrombin) 2.78096
HBZ hemoglobin, zeta 2.78096
KRT72 keratin 72, type II 2.78096
ACOT12 acyl-CoA thioesterase 12 2.78096
MYBPC3 myosin binding protein C, cardiac 2.78096
THSD1 thrombospondin, type I, domain containing 1 2.78096
NMUR2 neuromedin U receptor 2 2.78096
HES2 hes family bHLH transcription factor 2 2.78096
GPAT2 glycerol-3-phosphate acyltransferase 2, mitochondrial 2.78096
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3 2.78096
TACC3 transforming, acidic coiled-coil containing protein 3 2.78096
NPPB natriuretic peptide B 2.78096
CELF3 CUGBP, Elav-like family member 3 2.78096
RNF133 ring finger protein 133 2.78096
TCHH trichohyalin 2.78096
GSTM4 glutathione S-transferase mu 4 2.78096
SKOR2 SKI family transcriptional corepressor 2 2.78096
UBE2U ubiquitin-conjugating enzyme E2U (putative) 2.78096
NRROS negative regulator of reactive oxygen species 2.78096
RAPSN receptor-associated protein of the synapse 2.78096
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5 2.78096
CYP4A22 cytochrome P450, family 4, subfamily A, polypeptide 22 2.78096
SPMAP2L sperm microtubule associated protein 2 like 2.78096
MIOX myo-inositol oxygenase 2.78096
FCMR Fc fragment of IgM receptor 2.78096
SPATA25 spermatogenesis associated 25 2.78096
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 2.78096
UBE2QL1 ubiquitin-conjugating enzyme E2Q family-like 1 2.78096
ARL8A ADP-ribosylation factor-like 8A 2.78096
ACE2 angiotensin I converting enzyme 2 2.78096
TOX3 TOX high mobility group box family member 3 2.78096
CYLC2 cylicin, basic protein of sperm head cytoskeleton 2 2.78096
C1QTNF9B C1q and tumor necrosis factor related protein 9B 2.78096
CIMIP2B ciliary microtubule inner protein 2B 2.78096
H3C14 H3 clustered histone 14 2.78096
SERTM2 serine rich and transmembrane domain containing 2 2.78096
TEX13C TEX13 family member C 2.78096
TCIM transcriptional and immune response regulator 2.78096
TMEM271 transmembrane protein 271 2.78096
CFAP65 cilia and flagella associated protein 65 2.78096
SFTPA1 surfactant protein A1 2.78096
USH1G Usher syndrome 1G (autosomal recessive) 2.78096
LRRC70 leucine rich repeat containing 70 2.78096
PLEK2 pleckstrin 2 2.78096
PANX3 pannexin 3 2.78096
IRF5 interferon regulatory factor 5 2.78096
FOXD1 forkhead box D1 2.78096
RS1 retinoschisin 1 2.78096
CPNE6 copine VI (neuronal) 2.78096
RAET1G retinoic acid early transcript 1G 2.78096
ACR acrosin 2.78096
GPR4 G protein-coupled receptor 4 2.78096
CHRD chordin 2.78096
DAO D-amino-acid oxidase 2.78096
SAA1 serum amyloid A1 2.78096
CCR4 chemokine (C-C motif) receptor 4 2.78096
CCR3 chemokine (C-C motif) receptor 3 2.78096
KLRF1 killer cell lectin-like receptor subfamily F, member 1 2.78096
MYH13 myosin, heavy chain 13, skeletal muscle 2.78096
TPTE transmembrane phosphatase with tensin homology 2.78096
PPIL3 peptidylprolyl isomerase (cyclophilin)-like 3 2.78096
OR2AT4 olfactory receptor, family 2, subfamily AT, member 4 2.78096
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound 2.78096
ZNF765 zinc finger protein 765 2.78096
FZD7 frizzled class receptor 7 2.78096
OTC ornithine carbamoyltransferase 2.78096
PIH1D2 PIH1 domain containing 2 2.78096
CRYBB3 crystallin, beta B3 2.78096
CLRN3 clarin 3 2.78096
CTAGE1 cutaneous T-cell lymphoma-associated antigen 1 2.78096
NANOGNB NANOG neighbor homeobox 2.78096
KLF2 Kruppel-like factor 2 2.78096
WFDC6 WAP four-disulfide core domain 6 2.78096
SLC6A17 solute carrier family 6 (neutral amino acid transporter), member 17 2.78096
LCT lactase 2.78096
SUPT20HL1 suppressor of Ty 20 homolog (S. cerevisiae)-like 1 2.78096
ZSCAN4 zinc finger and SCAN domain containing 4 2.78096
DHRS7C dehydrogenase/reductase (SDR family) member 7C 2.78096
HSPB9 heat shock protein, alpha-crystallin-related, B9 2.78096
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion 2.78096
ESAM endothelial cell adhesion molecule 2.78096
MORC1 MORC family CW-type zinc finger 1 2.78096
CABP1 calcium binding protein 1 2.78096
NACAD NAC alpha domain containing 2.78096
CCDC152 coiled-coil domain containing 152 2.78096
GFI1B growth factor independent 1B transcription repressor 2.78096
WNT7A wingless-type MMTV integration site family, member 7A 2.78096
BCO1 beta-carotene oxygenase 1 2.78096
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 2.78096
PSG9 pregnancy specific beta-1-glycoprotein 9 2.78096
DCT dopachrome tautomerase 2.78096
HMGB4 high mobility group box 4 2.78096
DEFB135 defensin, beta 135 2.78096
REG1A regenerating islet-derived 1 alpha 2.78096
WNT10A wingless-type MMTV integration site family, member 10A 2.78096
CNR2 cannabinoid receptor 2 (macrophage) 2.78096
TTC23 tetratricopeptide repeat domain 23 2.78096
CFP complement factor properdin 2.78096
SLC38A3 solute carrier family 38, member 3 2.78096
TSPYL6 TSPY-like 6 2.78096
ZC3H12D zinc finger CCCH-type containing 12D 2.78096
IL1A interleukin 1, alpha 2.78096
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 2.78096
HRCT1 histidine rich carboxyl terminus 1 2.78096
SIAH3 siah E3 ubiquitin protein ligase family member 3 2.78096
PLA1A phospholipase A1 member A 2.78096
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 2.78096
ASTL astacin-like metallo-endopeptidase (M12 family) 2.78096
UTS2B urotensin 2B 2.78096
OCM oncomodulin 2.78096
SLC36A3 solute carrier family 36, member 3 2.78096
FGF17 fibroblast growth factor 17 2.78096
FITM1 fat storage-inducing transmembrane protein 1 2.78096
ALLC allantoicase 2.78096
C10ORF90 chromosome 10 open reading frame 90 2.78096
ARGFX arginine-fifty homeobox 2.78096
LRRC31 leucine rich repeat containing 31 2.78096
OR56B1 olfactory receptor, family 56, subfamily B, member 1 2.78096
CIB4 calcium and integrin binding family member 4 2.78096
CGA glycoprotein hormones, alpha polypeptide 2.78096
ITPKA inositol-trisphosphate 3-kinase A 2.78096
TGM3 transglutaminase 3 2.78096
SLC38A11 solute carrier family 38, member 11 2.78096
ANGPTL5 angiopoietin-like 5 2.78096
DDX53 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 2.78096
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 2.78096
ABCA10 ATP-binding cassette, sub-family A (ABC1), member 10 2.78096
SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) 2.78096
GHRH growth hormone releasing hormone 2.78096
NLRP3 NLR family, pyrin domain containing 3 2.78096
TRPM8 transient receptor potential cation channel, subfamily M, member 8 2.78096
OR14A2 olfactory receptor, family 14, subfamily A, member 2 2.78096
AMER3 APC membrane recruitment protein 3 2.78096
TRPM2 transient receptor potential cation channel, subfamily M, member 2 2.78096
GPR12 G protein-coupled receptor 12 2.77895
RBM3 RNA binding motif (RNP1, RRM) protein 3 2.77096
NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa 2.77096
USP15 ubiquitin specific peptidase 15 2.73968
BET1 Bet1 golgi vesicular membrane trafficking protein 2.73324
WIPI1 WD repeat domain, phosphoinositide interacting 1 2.70688
LEF1 lymphoid enhancer-binding factor 1 2.68621
COL11A2 collagen, type XI, alpha 2 2.68621
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit 2.67548
RBAK RB-associated KRAB zinc finger 2.64882
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2) 2.61869
IQSEC2 IQ motif and Sec7 domain 2 2.61869
TRAF5 TNF receptor-associated factor 5 2.61793
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein 2.46488
IGSF22 immunoglobulin superfamily, member 22 2.46488
C21ORF91 chromosome 21 open reading frame 91 2.45648
RUVBL1 RuvB-like AAA ATPase 1 2.4524
UBL3 ubiquitin-like 3 2.4524
TSPAN14 tetraspanin 14 2.45163
C1RL complement component 1, r subcomponent-like 2.44723
PGLS 6-phosphogluconolactonase 2.44509
CARMIL1 capping protein regulator and myosin 1 linker 1 2.43885
TLK2 tousled-like kinase 2 2.42456
EEIG2 EEIG family member 2 2.3871
BAG2 BCL2-associated athanogene 2 2.33784
SMS spermine synthase 2.33668
MUC16 mucin 16, cell surface associated 2.33569
HTR3E 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic 2.33569
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 2.32129
SPTSSB serine palmitoyltransferase, small subunit B 2.30887
MID1 midline 1 2.27875
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1 2.27875
COL4A4 collagen, type IV, alpha 4 2.27864
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 2.25129
RAB36 RAB36, member RAS oncogene family 2.25129
GUCY2F guanylate cyclase 2F, retinal 2.25129
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 2.21749
BCL3 B-cell CLL/lymphoma 3 2.20812
PIPOX pipecolic acid oxidase 2.19027
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) 2.17593
TFAP2E transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon) 2.123
GGNBP2 gametogenetin binding protein 2 2.12119
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 2.10678
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) 2.07638
ZNF468 zinc finger protein 468 2.07446
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 2.06698
LRRC17 leucine rich repeat containing 17 2.05521
ATAD3C ATPase family, AAA domain containing 3C 2.05521
RSPO4 R-spondin 4 2.0498
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) 2.01791
C17ORF58 chromosome 17 open reading frame 58 2.00596

decreased expression

Symbol Name Standardized Value
XIRP2 xin actin binding repeat containing 2 -2.93812
FYB2 FYN binding protein 2 -2.93812
ADAM20 ADAM metallopeptidase domain 20 -2.93812
DRD4 dopamine receptor D4 -2.93812
GTF2A1L general transcription factor IIA, 1-like -2.93812
C1QL3 complement component 1, q subcomponent-like 3 -2.93812
SLC25A34 solute carrier family 25, member 34 -2.93812
IRF7 interferon regulatory factor 7 -2.93812
GDA guanine deaminase -2.93812
PCDHB6 protocadherin beta 6 -2.78096
NAE1 NEDD8 activating enzyme E1 subunit 1 -2.78096
WWC1 WW and C2 domain containing 1 -2.78096
PARVA parvin, alpha -2.78096
TICAM1 toll-like receptor adaptor molecule 1 -2.78096
SCN4B sodium channel, voltage gated, type IV beta subunit -2.78096
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 -2.78096
MADCAM1 mucosal vascular addressin cell adhesion molecule 1 -2.78096
SNAI2 snail family zinc finger 2 -2.78096
UMAD1 UBAP1-MVB12-associated (UMA) domain containing 1 -2.78096
SACK1A scaffolding CK1 anchoring protein A -2.78096
SPATA22 spermatogenesis associated 22 -2.78096
TRPV5 transient receptor potential cation channel, subfamily V, member 5 -2.78096
TRPV3 transient receptor potential cation channel, subfamily V, member 3 -2.78096
CA1 carbonic anhydrase I -2.78096
ENTHD1 ENTH domain containing 1 -2.78096
MEIOSIN meiosis initiator -2.78096
ACBD5 acyl-CoA binding domain containing 5 -2.78096
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 -2.78096
GFRA3 GDNF family receptor alpha 3 -2.78096
SLC36A2 solute carrier family 36 (proton/amino acid symporter), member 2 -2.78096
GREP1 glycine rich extracellular protein 1 -2.78096
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 -2.78096
SEC14L3 SEC14-like 3 (S. cerevisiae) -2.78096
CDHR5 cadherin-related family member 5 -2.78096
TSPAN16 tetraspanin 16 -2.78096
SMIM45 small integral membrane protein 45 -2.78096
HECA headcase homolog (Drosophila) -2.74685
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 -2.66877
KANSL3 KAT8 regulatory NSL complex subunit 3 -2.63971
NPIPA2 nuclear pore complex interacting protein family, member A2 -2.63525
LOC728743 zinc finger protein pseudogene -2.61869
IGSF5 immunoglobulin superfamily, member 5 -2.61869
GPM6B glycoprotein M6B -2.60699
APOLD1 apolipoprotein L domain containing 1 -2.58018
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 -2.54908
H2AZ2 H2A.Z variant histone 2 -2.54284
DUSP1 dual specificity phosphatase 1 -2.51958
ZNF717 zinc finger protein 717 -2.50305
ENKD1 enkurin domain containing 1 -2.49313
SPON1 spondin 1, extracellular matrix protein -2.45279
PTPRB protein tyrosine phosphatase, receptor type, B -2.4524
SNRK SNF related kinase -2.44703
ZFP3 ZFP3 zinc finger protein -2.42456
BMAL2 basic helix-loop-helix ARNT like 2 -2.39738
ZNF512B zinc finger protein 512B -2.3887
ADGRG2 adhesion G protein-coupled receptor G2 -2.38827
ACSF2 acyl-CoA synthetase family member 2 -2.38628
FSAF1 40S small subunit processome assembly factor 1 -2.38604
PRRT1 proline-rich transmembrane protein 1 -2.38463
MBNL3 muscleblind-like splicing regulator 3 -2.37148
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B -2.36873
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2 -2.36096
CNTN3 contactin 3 (plasmacytoma associated) -2.34331
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 -2.32017
TCEANC2 transcription elongation factor A (SII) N-terminal and central domain containing 2 -2.30641
CBX3 chromobox homolog 3 -2.29123
PIAS2 protein inhibitor of activated STAT, 2 -2.2888
ANKRD63 ankyrin repeat domain 63 -2.27875
ZNF830 zinc finger protein 830 -2.2778
NTAN1 N-terminal asparagine amidase -2.26927
RPL8 ribosomal protein L8 -2.25229
MAZ MYC-associated zinc finger protein (purine-binding transcription factor) -2.22645
MDK midkine (neurite growth-promoting factor 2) -2.21044
ATP8B4 ATPase, class I, type 8B, member 4 -2.19103
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) -2.14894
ZBTB46 zinc finger and BTB domain containing 46 -2.12705
ILF3 interleukin enhancer binding factor 3, 90kDa -2.12457
ASB2 ankyrin repeat and SOCS box containing 2 -2.12404
HIC2 hypermethylated in cancer 2 -2.12404
ZBTB7C zinc finger and BTB domain containing 7C -2.11355
TBPL1 TBP-like 1 -2.10014
SAR1A secretion associated, Ras related GTPase 1A -2.08902
RPRD2 regulation of nuclear pre-mRNA domain containing 2 -2.08776
TULP3 tubby like protein 3 -2.07056
RABEP2 rabaptin, RAB GTPase binding effector protein 2 -2.06881
C14ORF93 chromosome 14 open reading frame 93 -2.06881
RBM41 RNA binding motif protein 41 -2.06881
TMEM123 transmembrane protein 123 -2.05726
MRPS17 mitochondrial ribosomal protein S17 -2.05521
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 -2.0498
EPC2 enhancer of polycomb homolog 2 (Drosophila) -2.04124
SAMD8 sterile alpha motif domain containing 8 -2.04124
GXYLT2 glucoside xylosyltransferase 2 -2.04124
NAGK N-acetylglucosamine kinase -2.0386
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -2.03246
FGF13 fibroblast growth factor 13 -2.02605
IL17RD interleukin 17 receptor D -2.01024
EXD1 exonuclease 3'-5' domain containing 1 -2.01024
SPMIP4 sperm microtubule inner protein 4 -2.01024