RHOG Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description ras homolog family member G|This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The encoded protein facilitates translocation of a functional guanine nucleotide exchange factor (GEF) complex from the cytoplasm to the plasma membrane where ras-related C3 botulinum toxin substrate 1 is activated to promote lamellipodium formation and cell migration. Two related pseudogene have been identified on chromosomes 20 and X. [provided by RefSeq, Aug 2011] (NCBI Entrez Gene Database, 391)
Similar Terms
Downloads & Tools

Genes

361 genes differentially expressed following the RHOG gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
SMIM23 small integral membrane protein 23 2.98692
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 2.98692
SMIM22 small integral membrane protein 22 2.98692
PTGER4 prostaglandin E receptor 4 (subtype EP4) 2.98692
IFITM5 interferon induced transmembrane protein 5 2.98692
OTUD6A OTU deubiquitinase 6A 2.98692
PSG3 pregnancy specific beta-1-glycoprotein 3 2.98692
MORC1 MORC family CW-type zinc finger 1 2.98692
OR2T8 olfactory receptor, family 2, subfamily T, member 8 2.98692
KLRF1 killer cell lectin-like receptor subfamily F, member 1 2.98692
ISLR2 immunoglobulin superfamily containing leucine-rich repeat 2 2.98692
LTK leukocyte receptor tyrosine kinase 2.98692
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 2.98692
CRH corticotropin releasing hormone 2.98692
NPFF neuropeptide FF-amide peptide precursor 2.98692
SPATA31G1 SPATA31 subfamily G member 1 2.98692
LCN1 lipocalin 1 2.98692
KLHL41 kelch-like family member 41 2.98692
C22ORF31 chromosome 22 open reading frame 31 2.98692
LRRC72 leucine rich repeat containing 72 2.98692
VSX1 visual system homeobox 1 2.98692
OTP orthopedia homeobox 2.98692
MAP3K7CL MAP3K7 C-terminal like 2.98692
SEPTIN12 septin 12 2.98692
NCF1 neutrophil cytosolic factor 1 2.83925
CEMP1 cementum protein 1 2.83925
OR51A7 olfactory receptor, family 51, subfamily A, member 7 2.83925
GLYAT glycine-N-acyltransferase 2.83925
KNG1 kininogen 1 2.83925
ZNF467 zinc finger protein 467 2.83925
PCDHB7 protocadherin beta 7 2.83925
DNASE1L2 deoxyribonuclease I-like 2 2.83925
SCG2 secretogranin II 2.83925
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 2.83925
SERPINA11 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11 2.83925
CRISP1 cysteine-rich secretory protein 1 2.83925
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 2.83925
GCC1 GRIP and coiled-coil domain containing 1 2.83925
ACVRL1 activin A receptor type II-like 1 2.83925
TMEM89 transmembrane protein 89 2.83925
GNG13 guanine nucleotide binding protein (G protein), gamma 13 2.83925
MUC22 mucin 22 2.83925
ACY3 aminoacylase 3 2.83925
FAM181B family with sequence similarity 181, member B 2.83925
TDRD9 tudor domain containing 9 2.83925
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 2.83925
ESX1 ESX homeobox 1 2.83925
OR10A2 olfactory receptor, family 10, subfamily A, member 2 2.83925
FOXR1 forkhead box R1 2.83925
GRP gastrin-releasing peptide 2.83925
DMRTC1B DMRT-like family C1B 2.83925
OLIG3 oligodendrocyte transcription factor 3 2.83925
TLX2 T-cell leukemia homeobox 2 2.83925
GYPB glycophorin B (MNS blood group) 2.83925
KCNU1 potassium channel, subfamily U, member 1 2.83925
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 2.83925
DENND11 DENN domain containing 11 2.83925
H3-5 H3.5 histone 2.83925
CES4A carboxylesterase 4A 2.83925
GBP1 guanylate binding protein 1, interferon-inducible 2.83925
AVPR1A arginine vasopressin receptor 1A 2.83925
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 2.83925
RD3 retinal degeneration 3 2.83925
TMIGD1 transmembrane and immunoglobulin domain containing 1 2.83925
CCN5 cellular communication network factor 5 2.83925
MSANTD5 Myb/SANT DNA binding domain containing 5 2.83925
ACKR5 atypical chemokine receptor 5 2.83925
SPATA31F3 SPATA31 subfamily F member 3 2.83925
CIMIP2C ciliary microtubule inner protein 2C 2.83925
TBC1D3I TBC1 domain family member 3I 2.83925
FAM240A family with sequence similarity 240 member A 2.83925
SMIM35 small integral membrane protein 35 2.83925
H2BW1 H2B.W histone 1 2.83925
PCARE photoreceptor cilium actin regulator 2.83925
IQCF3 IQ motif containing F3 2.83925
SELL selectin L 2.83925
MAL mal, T-cell differentiation protein 2.83925
PTGDR2 prostaglandin D2 receptor 2 2.83925
WDR38 WD repeat domain 38 2.83925
PTPRM protein tyrosine phosphatase, receptor type, M 2.83925
PRKAG3 protein kinase, AMP-activated, gamma 3 non-catalytic subunit 2.83925
DPF3 D4, zinc and double PHD fingers, family 3 2.83925
FAM187B family with sequence similarity 187, member B 2.83925
PLEKHG7 pleckstrin homology domain containing, family G (with RhoGef domain) member 7 2.83925
MEOX1 mesenchyme homeobox 1 2.83925
SLPI secretory leukocyte peptidase inhibitor 2.83925
ATP4B ATPase, H+/K+ exchanging, beta polypeptide 2.83925
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic 2.83925
CSAG1 chondrosarcoma associated gene 1 2.83925
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 2.83925
SPDYC speedy/RINGO cell cycle regulator family member C 2.83925
OR2L2 olfactory receptor, family 2, subfamily L, member 2 2.83925
CFAP45 cilia and flagella associated protein 45 2.83925
TBX3 T-box 3 2.83925
COXFA4L2 cytochrome c oxidase hypoxia associated subunit FA4L2 2.83925
PGR progesterone receptor 2.83925
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32 2.83925
CD5L CD5 molecule-like 2.83925
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1 2.83925
DEFB135 defensin, beta 135 2.83925
RGS13 regulator of G-protein signaling 13 2.83925
RIPK3 receptor-interacting serine-threonine kinase 3 2.83925
LRRC46 leucine rich repeat containing 46 2.83925
OR7G2 olfactory receptor, family 7, subfamily G, member 2 2.83925
ZNF474 zinc finger protein 474 2.83925
IL12B interleukin 12B 2.83925
SLFN12L schlafen family member 12-like 2.83925
KIF4B kinesin family member 4B 2.83925
DEFB119 defensin, beta 119 2.83925
REG1A regenerating islet-derived 1 alpha 2.83925
TRIM55 tripartite motif containing 55 2.83925
ODF4 outer dense fiber of sperm tails 4 2.83925
CD28 CD28 molecule 2.83925
DLX6 distal-less homeobox 6 2.83925
DMRTB1 DMRT-like family B with proline-rich C-terminal, 1 2.83925
BCL2A1 BCL2-related protein A1 2.83925
GFRAL GDNF family receptor alpha like 2.83925
ZC3H12D zinc finger CCCH-type containing 12D 2.83925
CTXN2 cortexin 2 2.83925
C8A complement component 8, alpha polypeptide 2.83925
UTS2R urotensin 2 receptor 2.83925
SST somatostatin 2.83925
TEX12 testis expressed 12 2.83925
ORM1 orosomucoid 1 2.83925
C8ORF89 chromosome 8 open reading frame 89 2.83925
VWA3B von Willebrand factor A domain containing 3B 2.83925
PLGLB2 plasminogen-like B2 2.83925
TMPRSS13 transmembrane protease, serine 13 2.83925
MYOZ2 myozenin 2 2.83925
OR6J1 olfactory receptor, family 6, subfamily J, member 1 (gene/pseudogene) 2.83925
OR52N4 olfactory receptor, family 52, subfamily N, member 4 (gene/pseudogene) 2.83925
WFDC11 WAP four-disulfide core domain 11 2.83925
ZNF648 zinc finger protein 648 2.83925
TMEM132C transmembrane protein 132C 2.83925
GALP galanin-like peptide 2.83925
LPCAT3 lysophosphatidylcholine acyltransferase 3 2.83925
TSSK1B testis-specific serine kinase 1B 2.83925
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 2.83925
RBP4 retinol binding protein 4, plasma 2.83925
RNASE7 ribonuclease, RNase A family, 7 2.83925
GRAPL GRB2-related adaptor protein-like 2.83925
CASQ2 calsequestrin 2 (cardiac muscle) 2.83925
FGF10 fibroblast growth factor 10 2.83925
LYZL1 lysozyme-like 1 2.83925
OR52N5 olfactory receptor, family 52, subfamily N, member 5 2.83925
CD8B2 CD8b2 molecule 2.81386
TEX19 testis expressed 19 2.80052
MAGEF1 melanoma antigen family F1 2.79448
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 2.78008
KIF12 kinesin family member 12 2.78008
COL17A1 collagen, type XVII, alpha 1 2.76218
PCSK4 proprotein convertase subtilisin/kexin type 4 2.75016
RNASET2 ribonuclease T2 2.68327
FMNL3 formin-like 3 2.68327
NELFB negative elongation factor complex member B 2.67579
GDAP1 ganglioside induced differentiation associated protein 1 2.6611
USP12 ubiquitin specific peptidase 12 2.61295
FPGS folylpolyglutamate synthase 2.58915
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 2.54123
BCL2L1 BCL2-like 1 2.53481
EPHB2 EPH receptor B2 2.5112
DTNB dystrobrevin, beta 2.50293
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 2.46555
ZNF417 zinc finger protein 417 2.46382
VAV2 vav 2 guanine nucleotide exchange factor 2.44135
FBP1 fructose-1,6-bisphosphatase 1 2.43685
ZNF91 zinc finger protein 91 2.41641
CIB1 calcium and integrin binding 1 (calmyrin) 2.4097
ADARB2 adenosine deaminase, RNA-specific, B2 (non-functional) 2.40543
RIT2 Ras-like without CAAX 2 2.38432
ZNF688 zinc finger protein 688 2.37921
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1 2.35387
NADK NAD kinase 2.34701
GPRC5C G protein-coupled receptor, class C, group 5, member C 2.32801
UBL3 ubiquitin-like 3 2.32023
UBC ubiquitin C 2.31484
FAM234B family with sequence similarity 234 member B 2.30759
ZNF768 zinc finger protein 768 2.295
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 2.29115
HAO2 hydroxyacid oxidase 2 (long chain) 2.28571
YBEY ybeY metallopeptidase (putative) 2.28571
PCDH18 protocadherin 18 2.28059
CD2BP2 CD2 (cytoplasmic tail) binding protein 2 2.28036
MYNN myoneurin 2.28036
CSAG3 CSAG family, member 3 2.26196
SGO2 shugoshin 2 2.25982
PGA5 pepsinogen 5, group I (pepsinogen A) 2.25659
RBM43 RNA binding motif protein 43 2.24142
DENND6B DENN/MADD domain containing 6B 2.22768
KHDC1 KH homology domain containing 1 2.2239
FSIP1 fibrous sheath interacting protein 1 2.20423
MTMR11 myotubularin related protein 11 2.19326
KAT6A K(lysine) acetyltransferase 6A 2.19326
CPNE3 copine III 2.16953
MAU2 MAU2 sister chromatid cohesion factor 2.15957
NMNAT1 nicotinamide nucleotide adenylyltransferase 1 2.14968
PDXK pyridoxal (pyridoxine, vitamin B6) kinase 2.14615
STRAP serine/threonine kinase receptor associated protein 2.1458
NUDT14 nudix (nucleoside diphosphate linked moiety X)-type motif 14 2.13973
CTSC cathepsin C 2.13359
SPARCL1 SPARC-like 1 (hevin) 2.12916
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha 2.12337
CEP135 centrosomal protein 135kDa 2.12337
NLE1 notchless homolog 1 (Drosophila) 2.09375
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 2.06989
ZNF468 zinc finger protein 468 2.06116
HFM1 HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae) 2.05914
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 2.05894
CNTNAP3 contactin associated protein-like 3 2.05887
NADSYN1 NAD synthetase 1 2.05342
CNTNAP5 contactin associated protein-like 5 2.05342
POGLUT1 protein O-glucosyltransferase 1 2.02838
TMEM39A transmembrane protein 39A 2.02674
STX16 syntaxin 16 2.02395
TLNRD1 talin rod domain containing 1 2.01846
ADCK1 aarF domain containing kinase 1 2.01276
PLP1 proteolipid protein 1 2.01276
RASA2 RAS p21 protein activator 2 2.01276
PNPLA5 patatin-like phospholipase domain containing 5 2.01276
SANBR SANT and BTB domain regulator of CSR 2.01276
CHD9NB CHD9 neighbor 2.00848

decreased expression

Symbol Name Standardized Value
SMIM41 small integral membrane protein 41 -2.98692
MSMP microseminoprotein, prostate associated -2.98692
SHC4 SHC (Src homology 2 domain containing) family, member 4 -2.98692
ADAM7 ADAM metallopeptidase domain 7 -2.98692
SKAP2 src kinase associated phosphoprotein 2 -2.83925
TRIM74 tripartite motif containing 74 -2.83925
C1ORF146 chromosome 1 open reading frame 146 -2.83925
KHDC3L KH domain containing 3-like, subcortical maternal complex member -2.83925
TSPAN8 tetraspanin 8 -2.83925
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 -2.83925
RNF31 ring finger protein 31 -2.83925
GLT6D1 glycosyltransferase 6 domain containing 1 -2.83925
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) -2.83925
NPAS3 neuronal PAS domain protein 3 -2.83925
ALDH18A1 aldehyde dehydrogenase 18 family, member A1 -2.83925
ANKRD33 ankyrin repeat domain 33 -2.83925
MORN2 MORN repeat containing 2 -2.83925
TMEM176B transmembrane protein 176B -2.83925
PDF peptide deformylase (mitochondrial) -2.83925
ADRB1 adrenoceptor beta 1 -2.83925
FAM228A family with sequence similarity 228, member A -2.83925
OSTN osteocrin -2.83925
DYNAP dynactin associated protein -2.83925
TIMD4 T-cell immunoglobulin and mucin domain containing 4 -2.83925
GREP1 glycine rich extracellular protein 1 -2.83925
ACTL8 actin-like 8 -2.83925
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 -2.83925
SIX6 SIX homeobox 6 -2.83925
HLF hepatic leukemia factor -2.83925
INHBC inhibin, beta C -2.83925
ALDH4A1 aldehyde dehydrogenase 4 family, member A1 -2.83925
KCNK4 potassium channel, two pore domain subfamily K, member 4 -2.83925
CSTA cystatin A (stefin A) -2.83925
OXGR1 oxoglutarate (alpha-ketoglutarate) receptor 1 -2.83925
THBD thrombomodulin -2.83925
ESPNL espin-like -2.83925
FTL ferritin, light polypeptide -2.83925
TBX1 T-box 1 -2.83925
NTN4 netrin 4 -2.83925
KIAA0040 KIAA0040 -2.82372
IDNK idnK, gluconokinase homolog (E. coli) -2.81844
TMEM259 transmembrane protein 259 -2.78223
EGFL8 EGF-like-domain, multiple 8 -2.74816
RPS25 ribosomal protein S25 -2.74519
WWP1 WW domain containing E3 ubiquitin protein ligase 1 -2.73343
CCND2 cyclin D2 -2.73147
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B -2.68757
TUT4 terminal uridylyl transferase 4 -2.68327
RPS19 ribosomal protein S19 -2.68327
AFP alpha-fetoprotein -2.6611
BUB1B-PAK6 BUB1B-PAK6 readthrough -2.62179
WDR6 WD repeat domain 6 -2.59366
TYRO3 TYRO3 protein tyrosine kinase -2.58226
LARP4 La ribonucleoprotein domain family, member 4 -2.5537
ZWINT ZW10 interacting kinetochore protein -2.52527
GJD3 gap junction protein, delta 3, 31.9kDa -2.51683
PFDN1 prefoldin subunit 1 -2.47952
ZPBP zona pellucida binding protein -2.44404
LPCAT4 lysophosphatidylcholine acyltransferase 4 -2.44188
NUTM1 NUT midline carcinoma, family member 1 -2.44135
SLC30A9 solute carrier family 30 (zinc transporter), member 9 -2.42595
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor -2.40016
MUC4 mucin 4, cell surface associated -2.36937
OPTC opticin -2.34186
ZDHHC18 zinc finger, DHHC-type containing 18 -2.34186
TFE3 transcription factor binding to IGHM enhancer 3 -2.32801
FHIP2B FHF complex subunit HOOK interacting protein 2B -2.3241
GAB2 GRB2-associated binding protein 2 -2.3241
TRPV3 transient receptor potential cation channel, subfamily V, member 3 -2.32023
TMCC1 transmembrane and coiled-coil domain family 1 -2.32023
RHOG ras homolog family member G -2.29356
CDC27 cell division cycle 27 -2.28571
FCHO2 FCH domain only 2 -2.28571
STMN3 stathmin-like 3 -2.27575
NOTCH2NLA notch 2 N-terminal like A -2.27206
COX7C cytochrome c oxidase subunit VIIc -2.24652
ASCL3 achaete-scute family bHLH transcription factor 3 -2.24226
PLCD3 phospholipase C, delta 3 -2.24142
FSD1L fibronectin type III and SPRY domain containing 1-like -2.23933
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 -2.232
CNTLN centlein, centrosomal protein -2.22768
RAF1 Raf-1 proto-oncogene, serine/threonine kinase -2.22504
RPL41 ribosomal protein L41 -2.22504
LCA5L Leber congenital amaurosis 5-like -2.2207
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast) -2.20423
ANAPC4 anaphase promoting complex subunit 4 -2.19326
BTNL8 butyrophilin-like 8 -2.19326
AMBP alpha-1-microglobulin/bikunin precursor -2.19326
DGCR6 DiGeorge syndrome critical region gene 6 -2.19326
PSPN persephin -2.19326
TAS1R1 taste receptor, type 1, member 1 -2.19326
PRELID2 PRELI domain containing 2 -2.18863
ERFE erythroferrone -2.18283
ZNF718 zinc finger protein 718 -2.18122
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 -2.17604
ATCAY ataxia, cerebellar, Cayman type -2.17463
COPS9 COP9 signalosome subunit 9 -2.16953
NUCLEOLIN nucleolin multifunctional protein -2.16953
CRYGS crystallin, gamma S -2.16918
HGS hepatocyte growth factor-regulated tyrosine kinase substrate -2.15433
EDA2R ectodysplasin A2 receptor -2.14974
FRMD1 FERM domain containing 1 -2.14677
TYMS thymidylate synthetase -2.13776
AK4 adenylate kinase 4 -2.13691
MTA2 metastasis associated 1 family, member 2 -2.1358
GAA glucosidase, alpha; acid -2.13352
FERMT3 fermitin family member 3 -2.1333
PLPPR2 phospholipid phosphatase related 2 -2.13072
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 -2.12916
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 -2.12804
MECR mitochondrial trans-2-enoyl-CoA reductase -2.12337
ZNF398 zinc finger protein 398 -2.12337
TRIM68 tripartite motif containing 68 -2.12314
TCFL5 transcription factor-like 5 (basic helix-loop-helix) -2.10869
NBPF1 neuroblastoma breakpoint family, member 1 -2.10659
RPL39 ribosomal protein L39 -2.09375
ZNF518B zinc finger protein 518B -2.06846
COL1A1 collagen, type I, alpha 1 -2.05342
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa -2.05277
TNPO2 transportin 2 -2.04715
BRICD5 BRICHOS domain containing 5 -2.04715
PIGM phosphatidylinositol glycan anchor biosynthesis, class M -2.03967
B3GAT3 beta-1,3-glucuronyltransferase 3 -2.03919
ZBTB33 zinc finger and BTB domain containing 33 -2.03716
MSH3 mutS homolog 3 -2.02838
EEF1AKMT3 EEF1A lysine methyltransferase 3 -2.0241
ARL15 ADP-ribosylation factor-like 15 -2.01725
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -2.01467
CDK2AP1 cyclin-dependent kinase 2 associated protein 1 -2.01467
PLCD4 phospholipase C, delta 4 -2.01276
ART4 ADP-ribosyltransferase 4 (Dombrock blood group) -2.01276
CTC1 CTS telomere maintenance complex component 1 -2.01276
INHBE inhibin, beta E -2.01276
PROB1 proline-rich basic protein 1 -2.01276
DPY19L4 dpy-19-like 4 (C. elegans) -2.01276
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1 -2.01276
ALG3 ALG3, alpha-1,3- mannosyltransferase -2.01276
RNF214 ring finger protein 214 -2.01149
LIN28A lin-28 homolog A (C. elegans) -2.00848
EVI5 ecotropic viral integration site 5 -2.00848