RHOQ Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description ras homolog family member Q|This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The encoded protein is an important signalling protein for sarcomere assembly and has been shown to play a significant role in the exocytosis of the solute carrier family 2, facilitated glucose transporter member 4 and other proteins, possibly acting as the signal that turns on the membrane fusion machinery. Three related pseudogene have been identified on chromosomes 2 and 14. [provided by RefSeq, Aug 2011] (NCBI Entrez Gene Database, 23433)
External Link http://www.ncbi.nlm.nih.gov/gene/23433
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155 interacting proteins for RHOQ from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
A2M alpha-2-macroglobulin
ABR active BCR-related
ACTA1 actin, alpha 1, skeletal muscle
ACTA2 actin, alpha 2, smooth muscle, aorta
ACTB actin, beta
ACTBL2 actin, beta-like 2
ACTC1 actin, alpha, cardiac muscle 1
ACTG1 actin gamma 1
ACTG2 actin, gamma 2, smooth muscle, enteric
ACTR2 ARP2 actin-related protein 2 homolog (yeast)
AKAP13 A kinase (PRKA) anchor protein 13
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARHGAP1 Rho GTPase activating protein 1
ARHGAP11A Rho GTPase activating protein 11A
ARHGAP11B Rho GTPase activating protein 11B
ARHGAP12 Rho GTPase activating protein 12
ARHGAP15 Rho GTPase activating protein 15
ARHGAP17 Rho GTPase activating protein 17
ARHGAP18 Rho GTPase activating protein 18
ARHGAP19 Rho GTPase activating protein 19
ARHGAP20 Rho GTPase activating protein 20
ARHGAP22 Rho GTPase activating protein 22
ARHGAP23 Rho GTPase activating protein 23
ARHGAP24 Rho GTPase activating protein 24
ARHGAP25 Rho GTPase activating protein 25
ARHGAP26 Rho GTPase activating protein 26
ARHGAP28 Rho GTPase activating protein 28
ARHGAP29 Rho GTPase activating protein 29
ARHGAP30 Rho GTPase activating protein 30
ARHGAP31 Rho GTPase activating protein 31
ARHGAP33 Rho GTPase activating protein 33
ARHGAP35 Rho GTPase activating protein 35
ARHGAP36 Rho GTPase activating protein 36
ARHGAP39 Rho GTPase activating protein 39
ARHGAP4 Rho GTPase activating protein 4
ARHGAP40 Rho GTPase activating protein 40
ARHGAP44 Rho GTPase activating protein 44
ARHGAP5 Rho GTPase activating protein 5
ARHGAP6 Rho GTPase activating protein 6
ARHGAP8 Rho GTPase activating protein 8
ARHGAP9 Rho GTPase activating protein 9
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9
BCR breakpoint cluster region
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDC42BPG CDC42 binding protein kinase gamma (DMPK-like)
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CHN1 chimerin 1
CHN2 chimerin 2
COPB1 coatomer protein complex, subunit beta 1
COPG1 coatomer protein complex, subunit gamma 1
CRK v-crk avian sarcoma virus CT10 oncogene homolog
DEPDC1B DEP domain containing 1B
DEPDC7 DEP domain containing 7
DLC1 DLC1 Rho GTPase activating protein
DLG4 discs, large homolog 4 (Drosophila)
DOCK8 dedicator of cytokinesis 8
ECT2 epithelial cell transforming 2
ELAVL1 ELAV like RNA binding protein 1
EXOC1 exocyst complex component 1
EXOC2 exocyst complex component 2
EXOC3 exocyst complex component 3
EXOC4 exocyst complex component 4
EXOC5 exocyst complex component 5
EXOC6 exocyst complex component 6
EXOC7 exocyst complex component 7
EXOC8 exocyst complex component 8
F2RL2 coagulation factor II (thrombin) receptor-like 2
FAM13A family with sequence similarity 13, member A
FAM13B family with sequence similarity 13, member B
FGD1 FYVE, RhoGEF and PH domain containing 1
FGD2 FYVE, RhoGEF and PH domain containing 2
FGD3 FYVE, RhoGEF and PH domain containing 3
FGD4 FYVE, RhoGEF and PH domain containing 4
GMIP GEM interacting protein
GOPC golgi-associated PDZ and coiled-coil motif containing
GRIK1 glutamate receptor, ionotropic, kainate 1
GRIK2 glutamate receptor, ionotropic, kainate 2
GRIK3 glutamate receptor, ionotropic, kainate 3
GRIK4 glutamate receptor, ionotropic, kainate 4
GRIK5 glutamate receptor, ionotropic, kainate 5
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
HAP1 huntingtin-associated protein 1
HMHA1 histocompatibility (minor) HA-1
HTT huntingtin
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
ITSN1 intersectin 1 (SH3 domain protein)
KALRN kalirin, RhoGEF kinase
MCF2 MCF.2 cell line derived transforming sequence
MCF2L MCF.2 cell line derived transforming sequence-like
MYO1C myosin IC
MYO9B myosin IXB
NET1 neuroepithelial cell transforming 1
NGEF neuronal guanine nucleotide exchange factor
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OCRL oculocerebrorenal syndrome of Lowe
OPHN1 oligophrenin 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PARD6A par-6 family cell polarity regulator alpha
PARD6B par-6 family cell polarity regulator beta
PFN1 profilin 1
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLEKHG2 pleckstrin homology domain containing, family G (with RhoGef domain) member 2
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5
PRKCI protein kinase C, iota
PRKCZ protein kinase C, zeta
RACGAP1 Rac GTPase activating protein 1
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RALBP1 ralA binding protein 1
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
RASGRF2 Ras protein-specific guanine nucleotide-releasing factor 2
SH2B2 SH2B adaptor protein 2
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SORBS1 sorbin and SH3 domain containing 1
SOS1 son of sevenless homolog 1 (Drosophila)
SOS2 son of sevenless homolog 2 (Drosophila)
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
STARD13 StAR-related lipid transfer (START) domain containing 13
STARD8 StAR-related lipid transfer (START) domain containing 8
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
SYDE2 synapse defective 1, Rho GTPase, homolog 2 (C. elegans)
TAGAP T-cell activation RhoGTPase activating protein
TIAM1 T-cell lymphoma invasion and metastasis 1
TIAM2 T-cell lymphoma invasion and metastasis 2
TRIO trio Rho guanine nucleotide exchange factor
TRIP10 thyroid hormone receptor interactor 10
UBC ubiquitin C
VAV1 vav 1 guanine nucleotide exchange factor
VAV2 vav 2 guanine nucleotide exchange factor
VAV3 vav 3 guanine nucleotide exchange factor
WAS Wiskott-Aldrich syndrome
WASL Wiskott-Aldrich syndrome-like