RHOT1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description ras homolog family member T1| (NCBI Entrez Gene Database, 55288)
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Genes

328 genes differentially expressed following the RHOT1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
CLIP4 CAP-GLY domain containing linker protein family, member 4 2.97539
NXPH4 neurexophilin 4 2.97539
BTC betacellulin 2.97539
PON1 paraoxonase 1 2.97539
ADTRP androgen-dependent TFPI-regulating protein 2.97539
TMEM100 transmembrane protein 100 2.97539
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5 2.97539
SLC16A8 solute carrier family 16 (monocarboxylate transporter), member 8 2.97539
ASPA aspartoacylase 2.97539
C19ORF67 chromosome 19 open reading frame 67 2.97539
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy 2.97539
CD200R1L CD200 receptor 1-like 2.97539
NXPE2 neurexophilin and PC-esterase domain family, member 2 2.97539
PTGDR2 prostaglandin D2 receptor 2 2.97539
CAPN11 calpain 11 2.97539
KLHL35 kelch-like family member 35 2.97539
CFHR3 complement factor H-related 3 2.97539
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 2.97539
CCDC88A coiled-coil domain containing 88A 2.97539
SERPINA11 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11 2.97539
IGFL2 IGF-like family member 2 2.97539
GPR22 G protein-coupled receptor 22 2.97539
SPINT3 serine peptidase inhibitor, Kunitz type, 3 2.97539
TRIM77 tripartite motif containing 77 2.97539
MYL5 myosin, light chain 5, regulatory 2.97539
PNLDC1 poly(A)-specific ribonuclease (PARN)-like domain containing 1 2.97539
ZNF804B zinc finger protein 804B 2.97539
CYP4A22 cytochrome P450, family 4, subfamily A, polypeptide 22 2.97539
TLDC2 TBC/LysM-associated domain containing 2 2.97539
NPB neuropeptide B 2.97539
DHRS2 dehydrogenase/reductase (SDR family) member 2 2.97539
NPR3 natriuretic peptide receptor 3 2.97539
OR6B1 olfactory receptor, family 6, subfamily B, member 1 2.97539
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) 2.97539
HMX2 H6 family homeobox 2 2.97539
UBE2S ubiquitin-conjugating enzyme E2S 2.97539
UBA7 ubiquitin-like modifier activating enzyme 7 2.97539
SMIM5 small integral membrane protein 5 2.97539
RLN1 relaxin 1 2.97539
FOXJ1 forkhead box J1 2.97539
TAS2R13 taste receptor, type 2, member 13 2.97539
AVP arginine vasopressin 2.97539
MPO myeloperoxidase 2.97539
CPLX4 complexin 4 2.97539
APOA5 apolipoprotein A-V 2.97539
LOC124906892 uncharacterized LOC124906892 2.97539
CFAP299 cilia and flagella associated protein 299 2.97539
TMEM225B transmembrane protein 225B 2.97539
ERFE erythroferrone 2.97539
CFAP141 cilia and flagella associated protein 141 2.97539
CFAP157 cilia and flagella associated protein 157 2.97539
SPATA46 spermatogenesis associated 46 2.97539
ANGPTL8 angiopoietin like 8 2.97539
H1-6 H1.6 linker histone, cluster member 2.97539
PHF24 PHD finger protein 24 2.97539
CPHXL cytoplasmic polyadenylated homeobox like 2.97539
PEAK3 PEAK family member 3 2.97539
SAXO3 stabilizer of axonemal microtubules 3 2.97539
CATSPERT catsper channel auxiliary subunit tau 2.97539
CIMAP2 ciliary microtubule associated protein 2 2.97539
LOC114841035 uncharacterized LOC114841035 2.97539
HSFX4 heat shock transcription factor family, X-linked member 4 2.97539
FAM240C family with sequence similarity 240 member C 2.97539
LOC124902436 talanin 2.97539
RHEX regulator of hemoglobinization and erythroid cell expansion 2.97539
CENPVL1 centromere protein V like 1 2.97539
RAG2 recombination activating gene 2 2.97539
ST6GALNAC1 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 2.97539
ALX1 ALX homeobox 1 2.97539
CCR8 chemokine (C-C motif) receptor 8 2.97539
CCR3 chemokine (C-C motif) receptor 3 2.97539
EXOC3L1 exocyst complex component 3-like 1 2.97539
TMEM179 transmembrane protein 179 2.97539
FAM186A family with sequence similarity 186, member A 2.97539
PRRT1 proline-rich transmembrane protein 1 2.97539
RNF113B ring finger protein 113B 2.97539
TPTE transmembrane phosphatase with tensin homology 2.97539
BHLHA9 basic helix-loop-helix family, member a9 2.97539
ARHGAP15 Rho GTPase activating protein 15 2.97539
MCMDC2 minichromosome maintenance domain containing 2 2.97539
SPI1 Spi-1 proto-oncogene 2.97539
SPRR2A small proline-rich protein 2A 2.97539
RAB36 RAB36, member RAS oncogene family 2.97539
LY6H lymphocyte antigen 6 complex, locus H 2.97539
IMPG1 interphotoreceptor matrix proteoglycan 1 2.97539
ARMCX5-GPRASP2 ARMCX5-GPRASP2 readthrough 2.97539
GATA3 GATA binding protein 3 2.97539
CLEC6A C-type lectin domain family 6, member A 2.97539
ROPN1 rhophilin associated tail protein 1 2.97539
CBLN2 cerebellin 2 precursor 2.97539
RANBP3L RAN binding protein 3-like 2.97539
LRRK2 leucine-rich repeat kinase 2 2.97539
C20ORF144 chromosome 20 open reading frame 144 2.97539
KRT5 keratin 5, type II 2.97539
LRRC43 leucine rich repeat containing 43 2.97539
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 2.97539
PLA2G4B phospholipase A2, group IVB (cytosolic) 2.97539
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion 2.97539
CD177 CD177 molecule 2.97539
IL9R interleukin 9 receptor 2.97539
LY96 lymphocyte antigen 96 2.97539
NTSR2 neurotensin receptor 2 2.97539
PTGDS prostaglandin D2 synthase 21kDa (brain) 2.97539
TG thyroglobulin 2.97539
C5AR2 complement component 5a receptor 2 2.97539
AMN amnion associated transmembrane protein 2.97539
NIM1K NIM1 serine/threonine protein kinase 2.97539
EDN1 endothelin 1 2.97539
PLA1A phospholipase A1 member A 2.97539
CD53 CD53 molecule 2.97539
NIPAL4 NIPA-like domain containing 4 2.97539
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1 2.97539
OAZ3 ornithine decarboxylase antizyme 3 2.97539
ADAM7 ADAM metallopeptidase domain 7 2.97539
NOX1 NADPH oxidase 1 2.97539
CRHR1 corticotropin releasing hormone receptor 1 2.97539
AQP6 aquaporin 6, kidney specific 2.97539
ALOXE3 arachidonate lipoxygenase 3 2.97539
TEKT2 tektin 2 (testicular) 2.97539
POF1B premature ovarian failure, 1B 2.97539
CST7 cystatin F (leukocystatin) 2.97539
IFI44 interferon-induced protein 44 2.97539
CSTA cystatin A (stefin A) 2.97539
RGSL1 regulator of G-protein signaling like 1 2.97539
CROCC2 ciliary rootlet coiled-coil, rootletin family member 2 2.97539
ROM1 retinal outer segment membrane protein 1 2.97539
ZC3H11B zinc finger CCCH-type containing 11B pseudogene 2.97539
PPP1R3C protein phosphatase 1, regulatory subunit 3C 2.97539
TM4SF4 transmembrane 4 L six family member 4 2.97539
DRC7 dynein regulatory complex subunit 7 2.97539
LOXHD1 lipoxygenase homology domains 1 2.97539
TRAF3IP3 TRAF3 interacting protein 3 2.97539
C1ORF105 chromosome 1 open reading frame 105 2.97539
PCDH20 protocadherin 20 2.97539
WNT4 wingless-type MMTV integration site family, member 4 2.97539
CLNK cytokine-dependent hematopoietic cell linker 2.97539
CXORF58 chromosome X open reading frame 58 2.97539
LPA lipoprotein, Lp(a) 2.97539
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 2.97539
RIIAD1 regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1 2.97539
ZPLD1 zona pellucida-like domain containing 1 2.97539
TAS2R46 taste receptor, type 2, member 46 2.97539
SIGLEC15 sialic acid binding Ig-like lectin 15 2.97539
APOL6 apolipoprotein L, 6 2.97539
NT5DC4 5'-nucleotidase domain containing 4 2.97539
CLEC9A C-type lectin domain family 9, member A 2.97539
ANKRD55 ankyrin repeat domain 55 2.97539
PTCRA pre T-cell antigen receptor alpha 2.97539
FITM1 fat storage-inducing transmembrane protein 1 2.97539
CCNO cyclin O 2.97539
RIBC1 RIB43A domain with coiled-coils 1 2.97539
PRSS38 protease, serine, 38 2.97539
KCNH3 potassium channel, voltage gated eag related subfamily H, member 3 2.97539
HAND2 heart and neural crest derivatives expressed 2 2.97539
TRIM7 tripartite motif containing 7 2.97539
GPAT3 glycerol-3-phosphate acyltransferase 3 2.95921
BLOC1S3 biogenesis of lysosomal organelles complex-1, subunit 3 2.87921
LIME1 Lck interacting transmembrane adaptor 1 2.87921
RAMP2 receptor (G protein-coupled) activity modifying protein 2 2.83911
RHBDD2 rhomboid domain containing 2 2.71991
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 2.71991
CCDC81 coiled-coil domain containing 81 2.71779
TMEM80 transmembrane protein 80 2.69619
RPS26 ribosomal protein S26 2.69619
MTMR12 myotubularin related protein 12 2.69619
XPA xeroderma pigmentosum, complementation group A 2.61092
MVK mevalonate kinase 2.52899
DHFR2 dihydrofolate reductase 2 2.52813
AP3B1 adaptor-related protein complex 3, beta 1 subunit 2.46316
RFTN1 raftlin, lipid raft linker 1 2.44215
SLCO1A2 solute carrier organic anion transporter family, member 1A2 2.43847
ZNF595 zinc finger protein 595 2.42674
BSDC1 BSD domain containing 1 2.39409
CD81 CD81 molecule 2.38171
USP39 ubiquitin specific peptidase 39 2.3678
NOTCH2NLC notch 2 N-terminal like C 2.35633
PCDHGB1 protocadherin gamma subfamily B, 1 2.33793
ADAMTS10 ADAM metallopeptidase with thrombospondin type 1 motif, 10 2.32957
MRPL38 mitochondrial ribosomal protein L38 2.29182
ELAPOR2 endosome-lysosome associated apoptosis and autophagy regulator family member 2 2.2752
STS steroid sulfatase (microsomal), isozyme S 2.25153
NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa 2.24132
KIF20B kinesin family member 20B 2.23969
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 2.22747
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 2.22449
DIPK2A divergent protein kinase domain 2A 2.16687
SLC35B2 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2 2.15729
BBS2 Bardet-Biedl syndrome 2 2.15367
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 2.15335
TMSB10 thymosin beta 10 2.13384
HOMEZ homeobox and leucine zipper encoding 2.12595
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa 2.11511
ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif, 8 2.10821
KLHL8 kelch-like family member 8 2.09978
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 2.09864
ART3 ADP-ribosyltransferase 3 2.09189
SYT11 synaptotagmin XI 2.09189
KCTD4 potassium channel tetramerization domain containing 4 2.09189
GABRG1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 2.09189
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 2.09189
SZT2 seizure threshold 2 homolog (mouse) 2.09189
C1ORF167 chromosome 1 open reading frame 167 2.09189
PLP2 proteolipid protein 2 (colonic epithelium-enriched) 2.09189
ZBTB16 zinc finger and BTB domain containing 16 2.09189
ITLN2 intelectin 2 2.09189
ASB2 ankyrin repeat and SOCS box containing 2 2.09189
NHLH1 nescient helix loop helix 1 2.09189
PRCC papillary renal cell carcinoma (translocation-associated) 2.07421
APOL2 apolipoprotein L, 2 2.06787
RREB1 ras responsive element binding protein 1 2.06431
HELLS helicase, lymphoid-specific 2.02801
SIMC1 SUMO-interacting motifs containing 1 2.01901
METTL24 methyltransferase like 24 2.01665

decreased expression

Symbol Name Standardized Value
ARNT aryl hydrocarbon receptor nuclear translocator -2.97539
ANO9 anoctamin 9 -2.97539
DOK3 docking protein 3 -2.97539
LOC124902694 uncharacterized LOC124902694 -2.97539
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon -2.97539
PON3 paraoxonase 3 -2.97539
CCDC163 CCDC163 homolog -2.97539
DESI1 desumoylating isopeptidase 1 -2.97539
PLPP7 phospholipid phosphatase 7 (inactive) -2.97539
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 -2.97539
WNT5B wingless-type MMTV integration site family, member 5B -2.97539
DNAI2 dynein, axonemal, intermediate chain 2 -2.97539
FHDC1 FH2 domain containing 1 -2.76895
ZMAT3 zinc finger, matrin-type 3 -2.71231
CYP2F1 cytochrome P450, family 2, subfamily F, polypeptide 1 -2.69619
CCDC158 coiled-coil domain containing 158 -2.69619
CLUL1 clusterin-like 1 (retinal) -2.69619
ETV3L ets variant 3-like -2.69619
NBPF3 neuroblastoma breakpoint family, member 3 -2.69619
CFAP65 cilia and flagella associated protein 65 -2.69619
TMIGD2 transmembrane and immunoglobulin domain containing 2 -2.69619
F2 coagulation factor II (thrombin) -2.69619
WFDC1 WAP four-disulfide core domain 1 -2.69619
PRDM1 PR domain containing 1, with ZNF domain -2.69619
ATAD3C ATPase family, AAA domain containing 3C -2.69619
C2CD2L C2CD2-like -2.69619
ADM5 adrenomedullin 5 (putative) -2.69619
UPK1B uroplakin 1B -2.69619
CDC20B cell division cycle 20B -2.69619
ANKRD65 ankyrin repeat domain 65 -2.69619
GREP1 glycine rich extracellular protein 1 -2.69619
TLR5 toll-like receptor 5 -2.69619
RELN reelin -2.69619
MLIP muscular LMNA-interacting protein -2.69619
IL31RA interleukin 31 receptor A -2.69619
CTSO cathepsin O -2.69619
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2 -2.69619
PKP1 plakophilin 1 -2.69619
FOXN4 forkhead box N4 -2.69619
UPB1 ureidopropionase, beta -2.69619
GPR83 G protein-coupled receptor 83 -2.69619
AIFM3 apoptosis-inducing factor, mitochondrion-associated, 3 -2.69619
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa -2.69336
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit -2.667
ARHGAP30 Rho GTPase activating protein 30 -2.65173
ELOF1 elongation factor 1 homolog (S. cerevisiae) -2.6425
DMD dystrophin -2.62658
IFT38 intraflagellar transport 38 -2.62636
RIPOR3 RIPOR family member 3 -2.59588
MSR1 macrophage scavenger receptor 1 -2.58024
TRIM58 tripartite motif containing 58 -2.58024
SIGLEC10 sialic acid binding Ig-like lectin 10 -2.58024
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B -2.58024
RNFT1 ring finger protein, transmembrane 1 -2.50455
TGFBI transforming growth factor, beta-induced, 68kDa -2.50019
ZNF24 zinc finger protein 24 -2.47666
AKAP5 A kinase (PRKA) anchor protein 5 -2.46221
WDR49 WD repeat domain 49 -2.45821
RRP7A ribosomal RNA processing 7 homolog A (S. cerevisiae) -2.45557
NEK2 NIMA-related kinase 2 -2.43905
SVIP small VCP/p97-interacting protein -2.41408
ALDH1B1 aldehyde dehydrogenase 1 family, member B1 -2.3678
DOCK9 dedicator of cytokinesis 9 -2.35633
GDAP1 ganglioside induced differentiation associated protein 1 -2.32957
MTHFSD methenyltetrahydrofolate synthetase domain containing -2.31905
AKT2 v-akt murine thymoma viral oncogene homolog 2 -2.31905
PFDN4 prefoldin subunit 4 -2.31746
CCDC186 coiled-coil domain containing 186 -2.31746
FBXW4 F-box and WD repeat domain containing 4 -2.30495
FBXW11 F-box and WD repeat domain containing 11 -2.29182
KIFC2 kinesin family member C2 -2.29043
VEGFC vascular endothelial growth factor C -2.29043
ECH1 enoyl CoA hydratase 1, peroxisomal -2.28632
ACP5 acid phosphatase 5, tartrate resistant -2.28184
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 -2.27554
MCF2L2 MCF.2 cell line derived transforming sequence-like 2 -2.24147
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) -2.23969
HEYL hes-related family bHLH transcription factor with YRPW motif-like -2.23969
INPP5A inositol polyphosphate-5-phosphatase, 40kDa -2.23969
SLC35B4 solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4 -2.21356
TM2D3 TM2 domain containing 3 -2.21157
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 -2.21157
H2BC14 H2B clustered histone 14 -2.2085
CELF4 CUGBP, Elav-like family member 4 -2.14363
PTCH2 patched 2 -2.13384
MTMR10 myotubularin related protein 10 -2.13384
GABPA GA binding protein transcription factor, alpha subunit 60kDa -2.11707
ZNF526 zinc finger protein 526 -2.11707
DUS4L dihydrouridine synthase 4-like (S. cerevisiae) -2.10821
PLCD3 phospholipase C, delta 3 -2.108
NPIPB13 nuclear pore complex interacting protein family, member B13 -2.10192
DYNLT2 dynein light chain Tctex-type 2 -2.10187
GPR158 G protein-coupled receptor 158 -2.09539
OXNAD1 oxidoreductase NAD-binding domain containing 1 -2.09189
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) -2.09189
CFAP410 cilia and flagella associated protein 410 -2.09189
RHOT1 ras homolog family member T1 -2.09189
PNPLA7 patatin-like phospholipase domain containing 7 -2.08824
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal) -2.08824
PLXNA2 plexin A2 -2.08824
MAT1A methionine adenosyltransferase I, alpha -2.08824
FAM13C family with sequence similarity 13, member C -2.08824
ATL3 atlastin GTPase 3 -2.08824
WASF3 WAS protein family, member 3 -2.08215
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase -2.07677
ZMYM2 zinc finger, MYM-type 2 -2.07503
ATF6 activating transcription factor 6 -2.07285
OMG oligodendrocyte myelin glycoprotein -2.06787
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit -2.06631
XXYLT1 xyloside xylosyltransferase 1 -2.05492
CPAMD8 C3 and PZP-like, alpha-2-macroglobulin domain containing 8 -2.0365
MROH8 maestro heat-like repeat family member 8 -2.01901
INPP5F inositol polyphosphate-5-phosphatase F -2.01901
B3GLCT beta 3-glucosyltransferase -2.01901
SPDYE12 speedy/RINGO cell cycle regulator family member E12 -2.01144