RHOU GTPase cycle Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-9013420
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Genes

40 proteins participating in the RHOU GTPase cycle pathway from the Reactome Pathways 2024 dataset.

Symbol Name
ARHGAP30 Rho GTPase activating protein 30
ARHGAP31 Rho GTPase activating protein 31
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
CDC42 cell division cycle 42
CLTC clathrin, heavy chain (Hc)
DEPDC1B DEP domain containing 1B
DLG5 discs, large homolog 5 (Drosophila)
DST dystonin
EPHA2 EPH receptor A2
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GRB2 growth factor receptor-bound protein 2
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
IQGAP1 IQ motif containing GTPase activating protein 1
ITSN2 intersectin 2
MYO6 myosin VI
NCK1 NCK adaptor protein 1
NCK2 NCK adaptor protein 2
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PARD6A par-6 family cell polarity regulator alpha
PEAK1 pseudopodium-enriched atypical kinase 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PTK2B protein tyrosine kinase 2 beta
RHOU ras homolog family member U
SPTAN1 spectrin, alpha, non-erythrocytic 1
SPTBN1 spectrin, beta, non-erythrocytic 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
TXNL1 thioredoxin-like 1
USP9X ubiquitin specific peptidase 9, X-linked
VANGL1 VANGL planar cell polarity protein 1
WDR6 WD repeat domain 6
WWP2 WW domain containing E3 ubiquitin protein ligase 2