RHOU Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description ras homolog family member U|This gene encodes a member of the Rho family of GTPases. This protein can activate PAK1 and JNK1, and can induce filopodium formation and stress fiber dissolution. It may also mediate the effects of WNT1 signaling in the regulation of cell morphology, cytoskeletal organization, and cell proliferation. A non-coding transcript variant of this gene results from naturally occurring read-through transcription between this locus and the neighboring DUSP5P (dual specificity phosphatase 5 pseudogene) locus.[provided by RefSeq, Mar 2011] (NCBI Entrez Gene Database, 58480)
External Link https://ncbi.nlm.nih.gov/gene/58480
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Genes

499 genes differentially expressed following the RHOU gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.0175978
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.0146482
DLK1 delta-like 1 homolog (Drosophila) 0.0126013
RPS4Y1 ribosomal protein S4, Y-linked 1 0.0115447
PSIP1 PC4 and SFRS1 interacting protein 1 0.0114902
HMGB2 high mobility group box 2 0.0110111
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.0103521
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.0103501
SYNGR3 synaptogyrin 3 0.010127
ENO2 enolase 2 (gamma, neuronal) 0.0100187
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.00996448
CCNA2 cyclin A2 0.00969328
KIF20A kinesin family member 20A 0.00967425
RPA3 replication protein A3, 14kDa 0.00940142
MAPK1 mitogen-activated protein kinase 1 0.00909922
INSIG1 insulin induced gene 1 0.00906496
DPYD dihydropyrimidine dehydrogenase 0.009053
ASNS asparagine synthetase (glutamine-hydrolyzing) 0.00903728
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 0.00897109
DIRAS3 DIRAS family, GTP-binding RAS-like 3 0.00891855
LRRC17 leucine rich repeat containing 17 0.00887009
LTBP1 latent transforming growth factor beta binding protein 1 0.00883255
APOA1 apolipoprotein A-I 0.00876641
HP haptoglobin 0.00875482
PEG3 paternally expressed 3 0.00865143
MRTFB myocardin related transcription factor B 0.00846316
TMEM106C transmembrane protein 106C 0.0084344
AMDHD2 amidohydrolase domain containing 2 0.00840886
ANO10 anoctamin 10 0.00824963
ENC1 ectodermal-neural cortex 1 (with BTB domain) 0.0081813
CALML5 calmodulin-like 5 0.00818003
CETN2 centrin, EF-hand protein, 2 0.0081697
SDC2 syndecan 2 0.00805808
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.00800089
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.00799307
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.00797533
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 0.0079729
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B 0.00794306
SCN3A sodium channel, voltage gated, type III alpha subunit 0.00792559
APOC3 apolipoprotein C-III 0.00790924
RNASE6 ribonuclease, RNase A family, k6 0.00789375
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.00789284
ARL4A ADP-ribosylation factor-like 4A 0.00785749
C1QA complement component 1, q subcomponent, A chain 0.00783057
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.00782827
APOB apolipoprotein B 0.00782792
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 0.00782147
ADAMDEC1 ADAM-like, decysin 1 0.00778514
MSMO1 methylsterol monooxygenase 1 0.00775515
COPS4 COP9 signalosome subunit 4 0.00772773
FGFR3 fibroblast growth factor receptor 3 0.00771713
NELL2 NEL-like 2 (chicken) 0.00767957
ARID4A AT rich interactive domain 4A (RBP1-like) 0.0076578
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 0.00765152
PLPP3 phospholipid phosphatase 3 0.007644
FGF13 fibroblast growth factor 13 0.00764375
TMEM158 transmembrane protein 158 (gene/pseudogene) 0.00763298
CTSZ cathepsin Z 0.00760803
FABP7 fatty acid binding protein 7, brain 0.00757353
TSPAN5 tetraspanin 5 0.00755497
ECI2 enoyl-CoA delta isomerase 2 0.00754948
CXCL9 chemokine (C-X-C motif) ligand 9 0.00752428
PFKL phosphofructokinase, liver 0.00751754
APOA2 apolipoprotein A-II 0.00750158
TMEM14A transmembrane protein 14A 0.00746491
COL1A2 collagen, type I, alpha 2 0.00745235
FST follistatin 0.00739817
SIRT3 sirtuin 3 0.00733562
NEK2 NIMA-related kinase 2 0.00731381
PTN pleiotrophin 0.0073091
SGMS1 sphingomyelin synthase 1 0.00729778
CDC20 cell division cycle 20 0.0072751
NUP37 nucleoporin 37kDa 0.00727502
MDK midkine (neurite growth-promoting factor 2) 0.00727339
SUB1 SUB1 homolog (S. cerevisiae) 0.00726546
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) 0.00722394
PLBD1 phospholipase B domain containing 1 0.00720362
NUSAP1 nucleolar and spindle associated protein 1 0.00715329
PSRC1 proline/serine-rich coiled-coil 1 0.00715313
PCP4 Purkinje cell protein 4 0.00713242
LBR lamin B receptor 0.00711548
GLUL glutamate-ammonia ligase 0.00709271
DCXR dicarbonyl/L-xylulose reductase 0.00708842
EPAS1 endothelial PAS domain protein 1 0.00706073
PRKCB protein kinase C, beta 0.00705853
TMEM168 transmembrane protein 168 0.00704795
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 0.0070421
PRKCA protein kinase C, alpha 0.0070407
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.00701583
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 0.00698073
NR1D2 nuclear receptor subfamily 1, group D, member 2 0.00696087
MCM6 minichromosome maintenance complex component 6 0.00694607
CDK1 cyclin-dependent kinase 1 0.00692818
ZEB1 zinc finger E-box binding homeobox 1 0.00691768
RANBP1 RAN binding protein 1 0.00691643
SEC23A Sec23 homolog A (S. cerevisiae) 0.00691065
H1-10 H1.10 linker histone 0.00690166
RPS5 ribosomal protein S5 0.00689766
HPF1 histone PARylation factor 1 0.00685035
FASN fatty acid synthase 0.00684852
TNNT1 troponin T type 1 (skeletal, slow) 0.00679728
TMEM106B transmembrane protein 106B 0.00678817
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 0.006787
HMMR hyaluronan-mediated motility receptor (RHAMM) 0.00678662
BAG2 BCL2-associated athanogene 2 0.00677293
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 0.00675814
DBF4 DBF4 zinc finger 0.0067387
CDKN3 cyclin-dependent kinase inhibitor 3 0.00672458
CHI3L2 chitinase 3-like 2 0.00671555
APOC2 apolipoprotein C-II 0.00670007
SSBP2 single-stranded DNA binding protein 2 0.00669552
TMEM14B transmembrane protein 14B 0.00669354
KDM5D lysine (K)-specific demethylase 5D 0.00667268
MCUB mitochondrial calcium uniporter dominant negative subunit beta 0.00667147
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa 0.00665598
TOP2A topoisomerase (DNA) II alpha 170kDa 0.00663593
C12ORF29 chromosome 12 open reading frame 29 0.00660594
MTERF3 mitochondrial transcription termination factor 3 0.00659678
PLK1 polo-like kinase 1 0.00657142
KIFAP3 kinesin-associated protein 3 0.00655418
FGL2 fibrinogen-like 2 0.0065454
DEK DEK proto-oncogene 0.00653229
COLEC12 collectin sub-family member 12 0.00651859
VBP1 von Hippel-Lindau binding protein 1 0.00649814
HAUS4 HAUS augmin-like complex, subunit 4 0.00649787
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00649383
PRIM1 primase, DNA, polypeptide 1 (49kDa) 0.00647635
OIP5 Opa interacting protein 5 0.00646887
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 0.00646513
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 0.0064495
FAM3C family with sequence similarity 3, member C 0.00641524
CLDND1 claudin domain containing 1 0.00640509
CENPU centromere protein U 0.00639647
C1QB complement component 1, q subcomponent, B chain 0.00636215
PAGE4 P antigen family, member 4 (prostate associated) 0.00634152
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.00634095
WNT5A wingless-type MMTV integration site family, member 5A 0.00633413
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 0.00630364
EXOSC4 exosome component 4 0.00630165
BLVRB biliverdin reductase B 0.0062776
LEF1 lymphoid enhancer-binding factor 1 0.0062712
KYAT3 kynurenine aminotransferase 3 0.00626793
KLHDC3 kelch domain containing 3 0.00626384
UBE2N ubiquitin-conjugating enzyme E2N 0.00625622
CNN3 calponin 3, acidic 0.00624609
GINS1 GINS complex subunit 1 (Psf1 homolog) 0.00623185
AHSG alpha-2-HS-glycoprotein 0.00622628
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.00622172
ACAT2 acetyl-CoA acetyltransferase 2 0.00621733
TIPRL TOR signaling pathway regulator 0.00618085
UQCRC2 ubiquinol-cytochrome c reductase core protein II 0.0061715
RNASEH2A ribonuclease H2, subunit A 0.00616793
PBK PDZ binding kinase 0.00615458
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 0.00614607
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 0.00614331
SH3GLB2 SH3-domain GRB2-like endophilin B2 0.00612147
TOP2B topoisomerase (DNA) II beta 180kDa 0.00611602
CPVL carboxypeptidase, vitellogenic-like 0.00611416
NDP Norrie disease (pseudoglioma) 0.00609702
MAMLD1 mastermind-like domain containing 1 0.00606877
AK4 adenylate kinase 4 0.00604625
CCNB2 cyclin B2 0.00602091
BCHE butyrylcholinesterase 0.00601605
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 0.00601263
IQGAP2 IQ motif containing GTPase activating protein 2 0.00600842
PDLIM3 PDZ and LIM domain 3 0.00600162
UBE2S ubiquitin-conjugating enzyme E2S 0.0059998
LTF lactotransferrin 0.00598522
ELP4 elongator acetyltransferase complex subunit 4 0.00594214
HAS2 hyaluronan synthase 2 0.00593802
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 0.00593123
BIRC5 baculoviral IAP repeat containing 5 0.00592047
SPARCL1 SPARC-like 1 (hevin) 0.00591004
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E 0.00589034
PSPH phosphoserine phosphatase 0.00588893
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 0.00588107
BOLA1 bolA family member 1 0.00587351
C20ORF27 chromosome 20 open reading frame 27 0.00586063
CD99 CD99 molecule 0.00583804
SNX10 sorting nexin 10 0.00581253
CIAO3 cytosolic iron-sulfur assembly component 3 0.00580521
TMEM38B transmembrane protein 38B 0.00580167
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 0.00579231
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein 0.00579145
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 0.00579097
F13A1 coagulation factor XIII, A1 polypeptide 0.00578969
NIPSNAP2 nipsnap homolog 2 0.00578629
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 0.0057504
RCN2 reticulocalbin 2, EF-hand calcium binding domain 0.00574395
SDHAF3 succinate dehydrogenase complex assembly factor 3 0.00574008
EPHX2 epoxide hydrolase 2, cytoplasmic 0.00573455
ATP7A ATPase, Cu++ transporting, alpha polypeptide 0.00573361
RESF1 retroelement silencing factor 1 0.00573057
AARS1 alanyl-tRNA synthetase 1 0.00572313
KRAS Kirsten rat sarcoma viral oncogene homolog 0.00570706
ATAD2 ATPase family, AAA domain containing 2 0.00567855
TPSAB1 tryptase alpha/beta 1 0.00566172
AP1S2 adaptor-related protein complex 1, sigma 2 subunit 0.00564972
OXSM 3-oxoacyl-ACP synthase, mitochondrial 0.00563774
TCEAL2 transcription elongation factor A (SII)-like 2 0.00563723
GPHN gephyrin 0.00562696
GSAP gamma-secretase activating protein 0.00562415
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 0.0056146
GPC3 glypican 3 0.00560825
COMMD3 COMM domain containing 3 0.00560326
EIF1B eukaryotic translation initiation factor 1B 0.00560323
UFL1 UFM1-specific ligase 1 0.00560133
JCHAIN joining chain of multimeric IgA and IgM 0.00559787
THY1 Thy-1 cell surface antigen 0.0055894
HPR haptoglobin-related protein 0.00558888
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.00558379
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 0.00558282
ORC5 origin recognition complex, subunit 5 0.00558098
SRSF1 serine/arginine-rich splicing factor 1 0.00558066
GNPAT glyceronephosphate O-acyltransferase 0.00557936
POLD1 polymerase (DNA directed), delta 1, catalytic subunit 0.00556213
FAM198B family with sequence similarity 198, member B 0.00556095
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.00555974
CENPF centromere protein F, 350/400kDa 0.00552883
DHCR7 7-dehydrocholesterol reductase 0.0055232
CRADD CASP2 and RIPK1 domain containing adaptor with death domain 0.00552182
CD2 CD2 molecule 0.00552099
NRGN neurogranin (protein kinase C substrate, RC3) 0.00551926
MCM2 minichromosome maintenance complex component 2 0.0055116
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 0.0055061
CTNNA2 catenin (cadherin-associated protein), alpha 2 0.00550599
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 0.00549946
SMYD2 SET and MYND domain containing 2 0.00548457
MLF1 myeloid leukemia factor 1 0.00547298
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) 0.00547136
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma 0.00546928
CD9 CD9 molecule 0.00546738
PDGFC platelet derived growth factor C 0.00546702
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 0.00545374
TMEM187 transmembrane protein 187 0.00544047
TADA2A transcriptional adaptor 2A 0.00543769
PLD3 phospholipase D family, member 3 0.00542613
METTL7A methyltransferase like 7A 0.00542528
MLH1 mutL homolog 1 0.00542356
GSTT1 glutathione S-transferase theta 1 0.00540212
FZD6 frizzled class receptor 6 0.0053984
POT1 protection of telomeres 1 0.00538993
NMU neuromedin U 0.00538313
TCEAL1 transcription elongation factor A (SII)-like 1 0.00536628
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 0.00535023
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 0.00534967
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.0053493
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha 0.00534349
GLOD4 glyoxalase domain containing 4 0.00533185
NQO1 NAD(P)H dehydrogenase, quinone 1 0.00532992

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0307409
CXCL8 chemokine (C-X-C motif) ligand 8 -0.0199676
HSPA1A heat shock 70kDa protein 1A -0.0163789
TFPI2 tissue factor pathway inhibitor 2 -0.0148379
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.0146082
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) -0.0143165
PROM1 prominin 1 -0.0138502
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -0.0135401
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.0130322
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.0130191
SGK1 serum/glucocorticoid regulated kinase 1 -0.0126717
MX1 MX dynamin-like GTPase 1 -0.012365
MGLL monoglyceride lipase -0.0119714
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) -0.0118675
TENT5A terminal nucleotidyltransferase 5A -0.0115987
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.011501
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.0114451
G0S2 G0/G1 switch 2 -0.0113977
AQP3 aquaporin 3 (Gill blood group) -0.0111212
ASS1 argininosuccinate synthase 1 -0.0108631
ISG15 ISG15 ubiquitin-like modifier -0.010667
RND3 Rho family GTPase 3 -0.010664
SLCO3A1 solute carrier organic anion transporter family, member 3A1 -0.0106071
CRK v-crk avian sarcoma virus CT10 oncogene homolog -0.0104758
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0103915
KLF6 Kruppel-like factor 6 -0.0103785
IFI6 interferon, alpha-inducible protein 6 -0.010329
IFI27 interferon, alpha-inducible protein 27 -0.0100335
IFI44L interferon-induced protein 44-like -0.0100196
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 -0.00998059
CRYAB crystallin, alpha B -0.0099605
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.00996004
CXCL5 chemokine (C-X-C motif) ligand 5 -0.0098909
PTHLH parathyroid hormone-like hormone -0.00971127
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 -0.00963619
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 -0.00957162
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 -0.00956844
ANXA3 annexin A3 -0.00956601
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.00942812
GNAS GNAS complex locus -0.00928231
HSPB8 heat shock 22kDa protein 8 -0.00927565
KDSR 3-ketodihydrosphingosine reductase -0.00927192
CXCL6 chemokine (C-X-C motif) ligand 6 -0.00926538
ZNF160 zinc finger protein 160 -0.00923452
C8ORF4 chromosome 8 open reading frame 4 -0.00923075
AGTR1 angiotensin II receptor, type 1 -0.00917513
ATF3 activating transcription factor 3 -0.00917323
IRS2 insulin receptor substrate 2 -0.00916775
NPY1R neuropeptide Y receptor Y1 -0.00898978
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40 -0.00898887
HMOX1 heme oxygenase 1 -0.0089852
FABP4 fatty acid binding protein 4, adipocyte -0.00894471
MX2 MX dynamin-like GTPase 2 -0.00893275
SAT1 spermidine/spermine N1-acetyltransferase 1 -0.00888218
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 -0.00887597
FHL2 four and a half LIM domains 2 -0.00887332
IL1RN interleukin 1 receptor antagonist -0.00884607
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 -0.00882629
SLC35F2 solute carrier family 35, member F2 -0.00881369
FOSB FBJ murine osteosarcoma viral oncogene homolog B -0.00880361
MVP major vault protein -0.00873241
GABARAPL1 GABA(A) receptor-associated protein like 1 -0.00861287
RSAD2 radical S-adenosyl methionine domain containing 2 -0.00855386
STX3 syntaxin 3 -0.00847604
KLHL24 kelch-like family member 24 -0.00843457
LAMC2 laminin, gamma 2 -0.00842926
FBXW12 F-box and WD repeat domain containing 12 -0.0084131
NOTCH2NL notch 2 N-terminal like -0.0083836
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 -0.00835074
AQP1 aquaporin 1 (Colton blood group) -0.00832393
CTBP2 C-terminal binding protein 2 -0.00827741
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -0.00825525
PLAAT3 phospholipase A and acyltransferase 3 -0.00823426
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 -0.0082195
HSPA6 heat shock 70kDa protein 6 (HSP70B') -0.00820841
LCN2 lipocalin 2 -0.00818571
ZNF281 zinc finger protein 281 -0.0081634
XAF1 XIAP associated factor 1 -0.00814349
AMOTL2 angiomotin like 2 -0.00812838
RUNX3 runt-related transcription factor 3 -0.00809627
LAMP3 lysosomal-associated membrane protein 3 -0.00808938
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 -0.00808846
SLPI secretory leukocyte peptidase inhibitor -0.00806955
CXCL14 chemokine (C-X-C motif) ligand 14 -0.00801239
HIST1H2BD histone cluster 1, H2bd -0.00796695
IGF1R insulin-like growth factor 1 receptor -0.0079486
GDF15 growth differentiation factor 15 -0.00789352
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 -0.00777529
GSTP1 glutathione S-transferase pi 1 -0.00776555
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa -0.00775353
MIR22HG MIR22 host gene -0.00769758
IER5 immediate early response 5 -0.00767354
TGFBI transforming growth factor, beta-induced, 68kDa -0.00762719
SOX4 SRY (sex determining region Y)-box 4 -0.00762515
ADO 2-aminoethanethiol (cysteamine) dioxygenase -0.00760118
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 -0.00751376
AREG amphiregulin -0.00748875
DUSP5 dual specificity phosphatase 5 -0.00747858
IL6R interleukin 6 receptor -0.00743642
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -0.0074306
MMP7 matrix metallopeptidase 7 -0.00742504
PTGER4 prostaglandin E receptor 4 (subtype EP4) -0.00741504
TRIM29 tripartite motif containing 29 -0.00735762
S100A11 S100 calcium binding protein A11 -0.0073539
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa -0.00731644
RPS27L ribosomal protein S27-like -0.00729918
IRF7 interferon regulatory factor 7 -0.00729664
MKNK2 MAP kinase interacting serine/threonine kinase 2 -0.00729594
BICC1 BicC family RNA binding protein 1 -0.00727068
TACSTD2 tumor-associated calcium signal transducer 2 -0.00726305
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 -0.00724463
GRN granulin -0.00723269
RABEP2 rabaptin, RAB GTPase binding effector protein 2 -0.00722422
CUX1 cut-like homeobox 1 -0.00718188
GUSBP3 glucuronidase, beta pseudogene 3 -0.0071351
GAREM1 GRB2 associated regulator of MAPK1 subtype 1 -0.00710395
GLA galactosidase, alpha -0.00709503
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 -0.0070933
JUP junction plakoglobin -0.00709309
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -0.00708861
TAOK1 TAO kinase 1 -0.00706563
WSB1 WD repeat and SOCS box containing 1 -0.00703092
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type -0.00702364
TUFT1 tuftelin 1 -0.00699066
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa -0.00698316
SAMD9 sterile alpha motif domain containing 9 -0.00697662
OLFML2A olfactomedin-like 2A -0.00697094
SMAD7 SMAD family member 7 -0.00695272
SMAD3 SMAD family member 3 -0.00693536
COL1A1 collagen, type I, alpha 1 -0.00691034
ADIPOQ adiponectin, C1Q and collagen domain containing -0.00690001
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -0.00687775
RRAD Ras-related associated with diabetes -0.00687524
SP110 SP110 nuclear body protein -0.00686637
SFXN3 sideroflexin 3 -0.00685365
BAZ2B bromodomain adjacent to zinc finger domain, 2B -0.00684859
ZNF721 zinc finger protein 721 -0.00684211
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) -0.00683366
ADIRF adipogenesis regulatory factor -0.00682617
CRABP1 cellular retinoic acid binding protein 1 -0.00682003
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.00679746
EPHA2 EPH receptor A2 -0.00679661
SIK1 salt-inducible kinase 1 -0.00679547
ECM1 extracellular matrix protein 1 -0.00678144
RET ret proto-oncogene -0.00670658
RBPMS RNA binding protein with multiple splicing -0.00669157
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 -0.00668759
GPX3 glutathione peroxidase 3 -0.00665347
TMEM140 transmembrane protein 140 -0.00665341
PPA1 pyrophosphatase (inorganic) 1 -0.00663776
CCL20 chemokine (C-C motif) ligand 20 -0.0065915
VCL vinculin -0.00657475
XIC X chromosome inactivation center -0.00655329
ZMAT3 zinc finger, matrin-type 3 -0.00655197
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 -0.00651378
RUFY2 RUN and FYVE domain containing 2 -0.00647116
BTG2 BTG family, member 2 -0.00647073
ASPA aspartoacylase -0.00644852
KLK10 kallikrein-related peptidase 10 -0.00644472
DTX4 deltex 4, E3 ubiquitin ligase -0.0064295
PDZK1IP1 PDZK1 interacting protein 1 -0.00642752
JAK1 Janus kinase 1 -0.00641068
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 -0.00638852
PKD1P1 polycystic kidney disease 1 (autosomal dominant) pseudogene 1 -0.00636986
ZEB2 zinc finger E-box binding homeobox 2 -0.00636151
EGFL6 EGF-like-domain, multiple 6 -0.00634537
PXDC1 PX domain containing 1 -0.00633523
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa -0.00632563
PLIN1 perilipin 1 -0.00632346
CTSA cathepsin A -0.00631882
ZNF611 zinc finger protein 611 -0.00630428
PPIF peptidylprolyl isomerase F -0.00630353
TIMP1 TIMP metallopeptidase inhibitor 1 -0.00628205
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -0.00626131
GOLGA8A golgin A8 family, member A -0.00625866
LGALS13 lectin, galactoside-binding, soluble, 13 -0.00625567
SPATA20 spermatogenesis associated 20 -0.0062525
FOSL2 FOS-like antigen 2 -0.00625235
TGFA transforming growth factor, alpha -0.00623297
GOLGA8H golgin A8 family, member H -0.00623248
TNIP1 TNFAIP3 interacting protein 1 -0.00621605
PLAU plasminogen activator, urokinase -0.00620335
SASH1 SAM and SH3 domain containing 1 -0.00617986
CLEC3B C-type lectin domain family 3, member B -0.00617434
MTUS1 microtubule associated tumor suppressor 1 -0.00617102
BIK BCL2-interacting killer (apoptosis-inducing) -0.00616549
OASL 2'-5'-oligoadenylate synthetase-like -0.00616461
LIMCH1 LIM and calponin homology domains 1 -0.00616184
FAM222B family with sequence similarity 222, member B -0.00615529
FHL1 four and a half LIM domains 1 -0.00613509
NOLC1 nucleolar and coiled-body phosphoprotein 1 -0.00611792
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.00611172
RRAGD Ras-related GTP binding D -0.00610701
PRPF4 pre-mRNA processing factor 4 -0.00609668
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 -0.00609442
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) -0.00608168
WWC1 WW and C2 domain containing 1 -0.00607129
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila) -0.00606875
BASP1 brain abundant, membrane attached signal protein 1 -0.00606161
HBB hemoglobin, beta -0.00604794
TTC39A tetratricopeptide repeat domain 39A -0.00602316
SLC31A2 solute carrier family 31 (copper transporter), member 2 -0.00601907
THBS2 thrombospondin 2 -0.00600545
HBEGF heparin-binding EGF-like growth factor -0.00597524
SSH3 slingshot protein phosphatase 3 -0.0059493
MYO1B myosin IB -0.00593703
MAB21L1 mab-21-like 1 (C. elegans) -0.00591557
MICB MHC class I polypeptide-related sequence B -0.00590764
HIST1H2AC histone cluster 1, H2ac -0.0059072
SORBS3 sorbin and SH3 domain containing 3 -0.00590104
TCF7 transcription factor 7 (T-cell specific, HMG-box) -0.00588621
LAMB3 laminin, beta 3 -0.00588301
RBM26 RNA binding motif protein 26 -0.0058806
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) -0.00586012
TBX3 T-box 3 -0.005852
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II -0.00585069
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 -0.00584994
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 -0.00584488
TFF1 trefoil factor 1 -0.0058341
INSR insulin receptor -0.00582904
STK10 serine/threonine kinase 10 -0.00582478
DEFB1 defensin, beta 1 -0.00581644
ARMCX3 armadillo repeat containing, X-linked 3 -0.00580788
PXDN peroxidasin -0.00580465
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.00580216
HAUS2 HAUS augmin-like complex, subunit 2 -0.00579314
LCP1 lymphocyte cytosolic protein 1 (L-plastin) -0.00576972
MXRA5 matrix-remodelling associated 5 -0.00575935
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 -0.00574746
ZSWIM8 zinc finger, SWIM-type containing 8 -0.00574709
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 -0.00574351
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 -0.0057403
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides -0.00573462
PABPC3 poly(A) binding protein, cytoplasmic 3 -0.00572178
TSC22D2 TSC22 domain family, member 2 -0.00571606
PRR11 proline rich 11 -0.00568594
NR4A1 nuclear receptor subfamily 4, group A, member 1 -0.00568354
CASP10 caspase 10, apoptosis-related cysteine peptidase -0.0056824
PLK2 polo-like kinase 2 -0.00567579
LIMA1 LIM domain and actin binding 1 -0.00567177
NCK2 NCK adaptor protein 2 -0.00565175
FGF1 fibroblast growth factor 1 (acidic) -0.00564722
IER3 immediate early response 3 -0.00563221
MFAP5 microfibrillar associated protein 5 -0.00561788
SPRR3 small proline-rich protein 3 -0.00558963
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha -0.00558516
CCND3 cyclin D3 -0.00557169
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 -0.00555814
ABHD4 abhydrolase domain containing 4 -0.00555615