RICTOR Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description RPTOR independent companion of MTOR, complex 2|RICTOR and MTOR (FRAP1; MIM 601231) are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth (Sarbassov et al., 2004 [PubMed 15268862]).[supplied by OMIM, Mar 2008] (NCBI Entrez Gene Database, 253260)
External Link http://www.ncbi.nlm.nih.gov/gene/253260
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Genes

222 interacting proteins for RICTOR from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ABHD16A abhydrolase domain containing 16A
ABLIM1 actin binding LIM protein 1
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT1S1 AKT1 substrate 1 (proline-rich)
AKT2 v-akt murine thymoma viral oncogene homolog 2
AKT3 v-akt murine thymoma viral oncogene homolog 3
AMPD2 adenosine monophosphate deaminase 2
ARAF A-Raf proto-oncogene, serine/threonine kinase
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
BAD BCL2-associated agonist of cell death
BAIAP2 BAI1-associated protein 2
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CAMKK1 calcium/calmodulin-dependent protein kinase kinase 1, alpha
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC6 coiled-coil domain containing 6
CDC25C cell division cycle 25C
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDK16 cyclin-dependent kinase 16
CDK17 cyclin-dependent kinase 17
CDK18 cyclin-dependent kinase 18
CDYL chromodomain protein, Y-like
CEP170 centrosomal protein 170kDa
CEP170B centrosomal protein 170B
CLASP1 cytoplasmic linker associated protein 1
CLASP2 cytoplasmic linker associated protein 2
CLTC clathrin, heavy chain (Hc)
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CRTC2 CREB regulated transcription coactivator 2
CRTC3 CREB regulated transcription coactivator 3
CUL1 cullin 1
CYFIP2 cytoplasmic FMR1 interacting protein 2
CYLD cylindromatosis (turban tumor syndrome)
DDB1 damage-specific DNA binding protein 1, 127kDa
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DENND1A DENN/MADD domain containing 1A
DENND4A DENN/MADD domain containing 4A
DENND4C DENN/MADD domain containing 4C
DEPTOR DEP domain containing MTOR-interacting protein
DHRS4 dehydrogenase/reductase (SDR family) member 4
DHRS7 dehydrogenase/reductase (SDR family) member 7
DHX36 DEAH (Asp-Glu-Ala-His) box polypeptide 36
DMTN dematin actin binding protein
DOCK11 dedicator of cytokinesis 11
EDC3 enhancer of mRNA decapping 3
EHMT2 euchromatic histone-lysine N-methyltransferase 2
EIF4E2 eukaryotic translation initiation factor 4E family member 2
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
ELAVL1 ELAV like RNA binding protein 1
EPB41L3 erythrocyte membrane protein band 4.1-like 3
ETV7 ets variant 7
EXO1 exonuclease 1
FBXO9 F-box protein 9
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FKBP8 FK506 binding protein 8, 38kDa
FLNA filamin A, alpha
FOXO3 forkhead box O3
GAPVD1 GTPase activating protein and VPS9 domains 1
GIGYF1 GRB10 interacting GYF protein 1
GIGYF2 GRB10 interacting GYF protein 2
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GNG2 guanine nucleotide binding protein (G protein), gamma 2
GRIP1 glutamate receptor interacting protein 1
HDAC1 histone deacetylase 1
HDAC4 histone deacetylase 4
HDAC5 histone deacetylase 5
HDAC7 histone deacetylase 7
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1
HSPA1B heat shock 70kDa protein 1B
HSPA4 heat shock 70kDa protein 4
ILK integrin-linked kinase
IRS2 insulin receptor substrate 2
IRS4 insulin receptor substrate 4
KIAA0355 KIAA0355
KIAA0930 KIAA0930
KIAA1671 KIAA1671
KIF1B kinesin family member 1B
KIF1C kinesin family member 1C
KLC2 kinesin light chain 2
KLC4 kinesin light chain 4
KRT10 keratin 10, type I
KSR1 kinase suppressor of ras 1
LARP1 La ribonucleoprotein domain family, member 1
LIMA1 LIM domain and actin binding 1
LIMS1 LIM and senescent cell antigen-like domains 1
LMO7 LIM domain 7
LUZP1 leucine zipper protein 1
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAPKAP1 mitogen-activated protein kinase associated protein 1
MARK1 MAP/microtubule affinity-regulating kinase 1
MARK2 MAP/microtubule affinity-regulating kinase 2
MARK3 MAP/microtubule affinity-regulating kinase 3
MAST2 microtubule associated serine/threonine kinase 2
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MTMR12 myotubularin related protein 12
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NADK NAD kinase
NAV1 neuron navigator 1
NCKAP1 NCK-associated protein 1
NCKIPSD NCK interacting protein with SH3 domain
NELFA negative elongation factor complex member A
NELFB negative elongation factor complex member B
NF1 neurofibromin 1
NUCLEOLIN nucleolin multifunctional protein
OTUD4 OTU deubiquitinase 4
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PARP8 poly (ADP-ribose) polymerase family, member 8
PDIA3 protein disulfide isomerase family A, member 3
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PHLDB2 pleckstrin homology-like domain, family B, member 2
PI4KB phosphatidylinositol 4-kinase, catalytic, beta
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PINK1 PTEN induced putative kinase 1
PKP2 plakophilin 2
PLD1 phospholipase D1, phosphatidylcholine-specific
PLD2 phospholipase D2
PLEKHA5 pleckstrin homology domain containing, family A member 5
PLEKHA7 pleckstrin homology domain containing, family A member 7
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1)
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PPP2R5D protein phosphatase 2, regulatory subunit B', delta
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
PRKCA protein kinase C, alpha
PRKCZ protein kinase C, zeta
PRMT5 protein arginine methyltransferase 5
PRPF31 pre-mRNA processing factor 31
PRR5 proline rich 5 (renal)
PRR5L proline rich 5 like
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PTPN14 protein tyrosine phosphatase, non-receptor type 14
PUM1 pumilio RNA-binding family member 1
R3HDM1 R3H domain containing 1
R3HDM2 R3H domain containing 2
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAB11FIP2 RAB11 family interacting protein 2 (class I)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6
RASAL2 RAS protein activator like 2
RBM10 RNA binding motif protein 10
RBX1 ring-box 1, E3 ubiquitin protein ligase
REEP4 receptor accessory protein 4
RNF2 ring finger protein 2
RPL13 ribosomal protein L13
RPL17 ribosomal protein L17
RPL23 ribosomal protein L23
RPL23A ribosomal protein L23a
RPL26 ribosomal protein L26
RPL7 ribosomal protein L7
RPS16 ribosomal protein S16
RPS18 ribosomal protein S18
RPS3A ribosomal protein S3A
RPS5 ribosomal protein S5
RPS6 ribosomal protein S6
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
RPS9 ribosomal protein S9
RPTOR regulatory associated protein of MTOR, complex 1
RTKN rhotekin
SACK1B scaffolding CK1 anchoring protein B
SAMD4A sterile alpha motif domain containing 4A
SAMD4B sterile alpha motif domain containing 4B
SFN stratifin
SGK1 serum/glucocorticoid regulated kinase 1
SH3PXD2A SH3 and PX domains 2A
SH3RF1 SH3 domain containing ring finger 1
SH3RF3 SH3 domain containing ring finger 3
SHKBP1 SH3KBP1 binding protein 1
SHROOM3 shroom family member 3
SIPA1L3 signal-induced proliferation-associated 1 like 3
SKIV2L2 superkiller viralicidic activity 2-like 2 (S. cerevisiae)
SORBS1 sorbin and SH3 domain containing 1
SORBS2 sorbin and SH3 domain containing 2
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
STK3 serine/threonine kinase 3
STK38 serine/threonine kinase 38
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
TBC1D22A TBC1 domain family, member 22A
TBC1D22B TBC1 domain family, member 22B
TBC1D4 TBC1 domain family, member 4
TBC1D5 TBC1 domain family, member 5
TELO2 telomere maintenance 2
TIA1 TIA1 cytotoxic granule-associated RNA binding protein
TP53BP2 tumor protein p53 binding protein 2
TPD52L1 tumor protein D52-like 1
TRIM32 tripartite motif containing 32
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2
TTC28 tetratricopeptide repeat domain 28
TTI1 TELO2 interacting protein 1
TUBA1A tubulin, alpha 1a
TUBA1B tubulin, alpha 1b
TUBB tubulin, beta class I
UBC ubiquitin C
UHRF1BP1L UHRF1 binding protein 1-like
USP54 ubiquitin specific peptidase 54
USP8 ubiquitin specific peptidase 8
USP9X ubiquitin specific peptidase 9, X-linked
VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
VPS33B vacuolar protein sorting 33 homolog B (yeast)
WDR77 WD repeat domain 77
WIZ widely interspaced zinc finger motifs
WNK1 WNK lysine deficient protein kinase 1
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZCCHC8 zinc finger, CCHC domain containing 8
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF24 zinc finger protein 24