| Dataset | GO Biological Process Annotations 2025 |
| Category | structural or functional annotations |
| Type | biological process |
| Description | Any series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) RIG-1 (also known as DDX58) binding to viral RNA. RIG-I detects RNA synthesized during active viral replication and triggers a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines. (Gene Ontology, GO_0039529) |
| External Link | http://amigo.geneontology.org/amigo/term/GO:0039529 |
| Similar Terms | |
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7 genes participating in the RIG-I signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset.
