RIPK2 Gene Set

Dataset Kinase Library Serine Threonine Kinome Atlas
Category proteomics
Type kinase
Description receptor-interacting serine-threonine kinase 2|This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 8767)
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Genes

100 substrates of the kinase RIPK2 from the Kinase Library Serine Threonine Kinome Atlas dataset.

Symbol Name Standardized Value
CDK17 cyclin-dependent kinase 17
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic)
DOCK6 dedicator of cytokinesis 6
DENND5B DENN/MADD domain containing 5B
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
LOC102724334 histone H2B type F-S-like
CASP9 caspase 9, apoptosis-related cysteine peptidase
NCF1 neutrophil cytosolic factor 1
HIST1H2BK histone cluster 1, H2bk
HIST1H2BH histone cluster 1, H2bh
HIST1H2BC histone cluster 1, H2bc
SPEG SPEG complex locus
HIST2H2BF histone cluster 2, H2bf
HIST2H2BE histone cluster 2, H2be
TUSC2 tumor suppressor candidate 2
CA13 carbonic anhydrase XIII
TNS1 tensin 1
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
RGL1 ral guanine nucleotide dissociation stimulator-like 1
MYD88 myeloid differentiation primary response 88
HIST1H2BD histone cluster 1, H2bd
RUNDC3A RUN domain containing 3A
KIAA1211L KIAA1211-like
RASAL3 RAS protein activator like 3
MTMR10 myotubularin related protein 10
CHEK1 checkpoint kinase 1
LAMTOR4 late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
ATG5 autophagy related 5
RTTN rotatin
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
PDE4A phosphodiesterase 4A, cAMP-specific
PDE4B phosphodiesterase 4B, cAMP-specific
PDE4C phosphodiesterase 4C, cAMP-specific
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
PRKCH protein kinase C, eta
RAB18 RAB18, member RAS oncogene family
SON SON DNA binding protein
HTT huntingtin
SACK1H scaffolding CK1 anchoring protein H
SACK1B scaffolding CK1 anchoring protein B
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8
MAPKAP1 mitogen-activated protein kinase associated protein 1
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
S1PR1 sphingosine-1-phosphate receptor 1
PDE4D phosphodiesterase 4D, cAMP-specific
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
DOCK2 dedicator of cytokinesis 2
RGCC regulator of cell cycle
SKI SKI proto-oncogene
SH2D4B SH2 domain containing 4B
HIPK2 homeodomain interacting protein kinase 2
ZNF624 zinc finger protein 624
ECH1 enoyl CoA hydratase 1, peroxisomal
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
STK11 serine/threonine kinase 11
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3
MOB1B MOB kinase activator 1B
MOB1A MOB kinase activator 1A
PTPN12 protein tyrosine phosphatase, non-receptor type 12
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
ZNF384 zinc finger protein 384
BCL2L11 BCL2-like 11 (apoptosis facilitator)
FERMT3 fermitin family member 3
PLD2 phospholipase D2
DOCK7 dedicator of cytokinesis 7
PDE7A phosphodiesterase 7A
RBM28 RNA binding motif protein 28
SYNM synemin, intermediate filament protein
GAB1 GRB2-associated binding protein 1
ZNF391 zinc finger protein 391
ZFP36 ZFP36 ring finger protein
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2
NET1 neuroepithelial cell transforming 1
DNAH3 dynein, axonemal, heavy chain 3
BRPF1 bromodomain and PHD finger containing, 1
LUZP1 leucine zipper protein 1
MYO10 myosin X
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
SETD1A SET domain containing 1A
NXF1 nuclear RNA export factor 1
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein
UNC119B unc-119 homolog B (C. elegans)
KIF4A kinesin family member 4A
DLG5 discs, large homolog 5 (Drosophila)
STARD13 StAR-related lipid transfer (START) domain containing 13
BLVRA biliverdin reductase A
DLG1 discs, large homolog 1 (Drosophila)
UBR5 ubiquitin protein ligase E3 component n-recognin 5
GSTP1 glutathione S-transferase pi 1
ZFP36L2 ZFP36 ring finger protein-like 2