| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | receptor-interacting serine-threonine kinase 2|This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 8767) |
| External Link | https://ncbi.nlm.nih.gov/gene/8767 |
| Similar Terms | |
| Downloads & Tools |
498 genes differentially expressed following the RIPK2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0132628 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0121458 |
| FCGBP | Fc fragment of IgG binding protein | 0.00883904 |
| EMX2 | empty spiracles homeobox 2 | 0.00859082 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.00751616 |
| GALC | galactosylceramidase | 0.00726523 |
| DPYD | dihydropyrimidine dehydrogenase | 0.00705011 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | 0.00690523 |
| DLK1 | delta-like 1 homolog (Drosophila) | 0.00681344 |
| IL1R1 | interleukin 1 receptor, type I | 0.00679242 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.00675748 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | 0.00660455 |
| CST3 | cystatin C | 0.00634781 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.00632771 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.0062927 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | 0.00625399 |
| GIMAP6 | GTPase, IMAP family member 6 | 0.00623763 |
| CFI | complement factor I | 0.00618675 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | 0.00616526 |
| COG2 | component of oligomeric golgi complex 2 | 0.00616498 |
| MFAP2 | microfibrillar-associated protein 2 | 0.00615195 |
| OLFM4 | olfactomedin 4 | 0.00603529 |
| MT1E | metallothionein 1E | 0.00603088 |
| EFNB2 | ephrin-B2 | 0.00600794 |
| TFF3 | trefoil factor 3 (intestinal) | 0.00598917 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.00597741 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.00589611 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 0.00587335 |
| ESR1 | estrogen receptor 1 | 0.00582357 |
| RPIA | ribose 5-phosphate isomerase A | 0.00582118 |
| C10ORF10 | chromosome 10 open reading frame 10 | 0.00581973 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.00581359 |
| CDC20 | cell division cycle 20 | 0.00576574 |
| DEFA5 | defensin, alpha 5, Paneth cell-specific | 0.00574454 |
| TPD52L2 | tumor protein D52-like 2 | 0.0056852 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | 0.00567983 |
| NRCAM | neuronal cell adhesion molecule | 0.00567554 |
| ABLIM1 | actin binding LIM protein 1 | 0.00566959 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.00556215 |
| TMEM45A | transmembrane protein 45A | 0.00556204 |
| MCM5 | minichromosome maintenance complex component 5 | 0.00555149 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.00554635 |
| MEOX2 | mesenchyme homeobox 2 | 0.00540933 |
| COL3A1 | collagen, type III, alpha 1 | 0.00539436 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 0.00538162 |
| TMEM176B | transmembrane protein 176B | 0.00536838 |
| MGP | matrix Gla protein | 0.0053624 |
| RNPS1 | RNA binding protein S1, serine-rich domain | 0.00528496 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | 0.00527421 |
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.00526563 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | 0.00525514 |
| NUAK1 | NUAK family, SNF1-like kinase, 1 | 0.00521696 |
| ANK2 | ankyrin 2, neuronal | 0.00519967 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 | 0.00519505 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 | 0.00518235 |
| FZD10 | frizzled class receptor 10 | 0.00517208 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.00515587 |
| GAS6 | growth arrest-specific 6 | 0.00515155 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | 0.00508424 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | 0.00507774 |
| BTBD3 | BTB (POZ) domain containing 3 | 0.00506494 |
| TBC1D4 | TBC1 domain family, member 4 | 0.00505377 |
| FMOD | fibromodulin | 0.00505288 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | 0.0050461 |
| SPARCL1 | SPARC-like 1 (hevin) | 0.00503895 |
| KIF14 | kinesin family member 14 | 0.00503686 |
| CCNB2 | cyclin B2 | 0.00501799 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.00500052 |
| PFKL | phosphofructokinase, liver | 0.00497206 |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 | 0.00496559 |
| CD200 | CD200 molecule | 0.00495078 |
| MT1M | metallothionein 1M | 0.00495062 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | 0.00494401 |
| CPVL | carboxypeptidase, vitellogenic-like | 0.0049262 |
| CLCA1 | chloride channel accessory 1 | 0.00492009 |
| ISOC1 | isochorismatase domain containing 1 | 0.00487925 |
| NMU | neuromedin U | 0.00487644 |
| FGL2 | fibrinogen-like 2 | 0.00486855 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.00483856 |
| TMEM176A | transmembrane protein 176A | 0.00481925 |
| DACT1 | dishevelled-binding antagonist of beta-catenin 1 | 0.00478003 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | 0.0047713 |
| DCLK1 | doublecortin-like kinase 1 | 0.00476981 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | 0.00474363 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.00474218 |
| KIF1B | kinesin family member 1B | 0.00473728 |
| MSX1 | msh homeobox 1 | 0.00472638 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | 0.00469189 |
| IQGAP2 | IQ motif containing GTPase activating protein 2 | 0.0046652 |
| SOX17 | SRY (sex determining region Y)-box 17 | 0.00465523 |
| NUDT15 | nudix (nucleoside diphosphate linked moiety X)-type motif 15 | 0.00461194 |
| FAM198B | family with sequence similarity 198, member B | 0.00458678 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 0.00456683 |
| EMP3 | epithelial membrane protein 3 | 0.0045585 |
| C3 | complement component 3 | 0.00455175 |
| MRPS28 | mitochondrial ribosomal protein S28 | 0.00453488 |
| MRPS2 | mitochondrial ribosomal protein S2 | 0.00452202 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.00448504 |
| SNX7 | sorting nexin 7 | 0.00448124 |
| LTF | lactotransferrin | 0.00447836 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 | 0.00447403 |
| APMAP | adipocyte plasma membrane associated protein | 0.00446119 |
| LMNB1 | lamin B1 | 0.00445482 |
| HSPA2 | heat shock 70kDa protein 2 | 0.0044404 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.00443169 |
| MAGEA3 | melanoma antigen family A3 | 0.00441954 |
| PDZRN3 | PDZ domain containing ring finger 3 | 0.00441265 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.00439995 |
| C1QB | complement component 1, q subcomponent, B chain | 0.00435543 |
| MT3 | metallothionein 3 | 0.00434197 |
| LRRC47 | leucine rich repeat containing 47 | 0.00428476 |
| PRUNE2 | prune homolog 2 (Drosophila) | 0.00427845 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00425276 |
| FABP7 | fatty acid binding protein 7, brain | 0.00424499 |
| GIMAP4 | GTPase, IMAP family member 4 | 0.00424421 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 0.00420906 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | 0.00420227 |
| MMP1 | matrix metallopeptidase 1 | 0.00417796 |
| MCM2 | minichromosome maintenance complex component 2 | 0.00417032 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00413771 |
| MT1G | metallothionein 1G | 0.00412154 |
| ADAMTS3 | ADAM metallopeptidase with thrombospondin type 1 motif, 3 | 0.0041125 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | 0.0041105 |
| STK38L | serine/threonine kinase 38 like | 0.00410407 |
| EDN3 | endothelin 3 | 0.00410318 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | 0.00409506 |
| ADSL | adenylosuccinate lyase | 0.0040895 |
| ASRGL1 | asparaginase like 1 | 0.00408338 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.00408299 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase | 0.00407904 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | 0.00407745 |
| TRAF5 | TNF receptor-associated factor 5 | 0.00406912 |
| PSRC1 | proline/serine-rich coiled-coil 1 | 0.00406864 |
| NOTCH2 | notch 2 | 0.00406457 |
| LAMA4 | laminin, alpha 4 | 0.00406278 |
| C1ORF174 | chromosome 1 open reading frame 174 | 0.00406237 |
| A2M | alpha-2-macroglobulin | 0.00405745 |
| CFH | complement factor H | 0.004047 |
| LRRC8B | leucine rich repeat containing 8 family, member B | 0.00403335 |
| MYBPC1 | myosin binding protein C, slow type | 0.00403274 |
| GAS7 | growth arrest-specific 7 | 0.00403055 |
| PPT1 | palmitoyl-protein thioesterase 1 | 0.00402389 |
| ELAPOR1 | endosome-lysosome associated apoptosis and autophagy regulator 1 | 0.00401843 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | 0.00400981 |
| MB | myoglobin | 0.00399865 |
| DPAGT1 | dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) | 0.00399653 |
| H2AX | H2A.X variant histone | 0.0039958 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.00398713 |
| C1QA | complement component 1, q subcomponent, A chain | 0.00398553 |
| PLBD1 | phospholipase B domain containing 1 | 0.00398458 |
| SYNGR2 | synaptogyrin 2 | 0.0039785 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 0.00396336 |
| RHOBTB1 | Rho-related BTB domain containing 1 | 0.00394731 |
| ELOVL2 | ELOVL fatty acid elongase 2 | 0.00394381 |
| SATB2 | SATB homeobox 2 | 0.00394075 |
| TUBB4B | tubulin, beta 4B class IVb | 0.00393378 |
| MT1HL1 | metallothionein 1H-like 1 | 0.00393301 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | 0.00392285 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.00391473 |
| VSIG4 | V-set and immunoglobulin domain containing 4 | 0.00390977 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | 0.00390883 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 0.00390523 |
| DEFA6 | defensin, alpha 6, Paneth cell-specific | 0.00390163 |
| ACAA2 | acetyl-CoA acyltransferase 2 | 0.00390073 |
| MFNG | MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 0.00389674 |
| CAPRIN2 | caprin family member 2 | 0.00388993 |
| C2CD5 | C2 calcium-dependent domain containing 5 | 0.00388974 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.00388445 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | 0.00387607 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.00386134 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.00385003 |
| EFNA5 | ephrin-A5 | 0.00384816 |
| SHOX2 | short stature homeobox 2 | 0.00383802 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.00383065 |
| SPAG7 | sperm associated antigen 7 | 0.00380228 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | 0.00379714 |
| TST | thiosulfate sulfurtransferase (rhodanese) | 0.00379268 |
| IL32 | interleukin 32 | 0.00377624 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.00377342 |
| TLCD3A | TLC domain containing 3A | 0.00377153 |
| CADPS2 | Ca++-dependent secretion activator 2 | 0.00376616 |
| CLEC10A | C-type lectin domain family 10, member A | 0.00376344 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 0.0037556 |
| LST1 | leukocyte specific transcript 1 | 0.00375095 |
| EPHB2 | EPH receptor B2 | 0.00374732 |
| UROD | uroporphyrinogen decarboxylase | 0.00374129 |
| COPS7A | COP9 signalosome subunit 7A | 0.00373257 |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) | 0.0037319 |
| GLS | glutaminase | 0.00372776 |
| ISLR | immunoglobulin superfamily containing leucine-rich repeat | 0.00372534 |
| MFAP5 | microfibrillar associated protein 5 | 0.00371975 |
| CD1E | CD1e molecule | 0.00371942 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.00371733 |
| GRAMD4 | GRAM domain containing 4 | 0.00371339 |
| PMP22 | peripheral myelin protein 22 | 0.00370941 |
| ADCY7 | adenylate cyclase 7 | 0.0037063 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.00370314 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.00370015 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.00369861 |
| CD320 | CD320 molecule | 0.00369782 |
| TMX1 | thioredoxin-related transmembrane protein 1 | 0.00369523 |
| SPC25 | SPC25, NDC80 kinetochore complex component | 0.00368829 |
| UBAC1 | UBA domain containing 1 | 0.00368714 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.00368136 |
| IGFBP4 | insulin-like growth factor binding protein 4 | 0.0036785 |
| DPM3 | dolichyl-phosphate mannosyltransferase polypeptide 3 | 0.00367812 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00367315 |
| AOC1 | amine oxidase, copper containing 1 | 0.0036703 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | 0.0036694 |
| ACTL6A | actin-like 6A | 0.00365652 |
| DHCR24 | 24-dehydrocholesterol reductase | 0.00363981 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.00363842 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | 0.00363429 |
| HAT1 | histone acetyltransferase 1 | 0.00363203 |
| NSG1 | neuron specific gene family member 1 | 0.00363035 |
| RAB11FIP2 | RAB11 family interacting protein 2 (class I) | 0.00362816 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.00362129 |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) | 0.0036182 |
| LPAR6 | lysophosphatidic acid receptor 6 | 0.00359925 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | 0.00359768 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | 0.0035915 |
| SUB1 | SUB1 homolog (S. cerevisiae) | 0.0035899 |
| PFAS | phosphoribosylformylglycinamidine synthase | 0.00358501 |
| RNF43 | ring finger protein 43 | 0.00358386 |
| PRC1 | protein regulator of cytokinesis 1 | 0.00358163 |
| ZNF106 | zinc finger protein 106 | 0.00357678 |
| ATP9B | ATPase, class II, type 9B | 0.0035724 |
| RBM14 | RNA binding motif protein 14 | 0.00356816 |
| CLTB | clathrin, light chain B | 0.00355912 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.00355632 |
| ICAM2 | intercellular adhesion molecule 2 | 0.0035533 |
| REG3A | regenerating islet-derived 3 alpha | 0.00354689 |
| CNR1 | cannabinoid receptor 1 (brain) | 0.00354644 |
| ANKRD27 | ankyrin repeat domain 27 (VPS9 domain) | 0.00354623 |
| MAOB | monoamine oxidase B | 0.00354037 |
| E2F8 | E2F transcription factor 8 | 0.00353523 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.00352697 |
| NCAPH | non-SMC condensin I complex, subunit H | 0.00350854 |
| ECT2 | epithelial cell transforming 2 | 0.00350201 |
| CD34 | CD34 molecule | 0.00350083 |
| TUBB3 | tubulin, beta 3 class III | 0.00349642 |
| FOXO4 | forkhead box O4 | 0.00349403 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.00349317 |
| NDC1 | NDC1 transmembrane nucleoporin | 0.00349301 |
| HPGDS | hematopoietic prostaglandin D synthase | 0.00349284 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.00349226 |
| S100A9 | S100 calcium binding protein A9 | 0.00348948 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | 0.00348413 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.00995191 |
| DSP | desmoplakin | -0.0088928 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.00842366 |
| ADM | adrenomedullin | -0.00765998 |
| NVL | nuclear VCP-like | -0.00762903 |
| S100P | S100 calcium binding protein P | -0.00737458 |
| RBM34 | RNA binding motif protein 34 | -0.00735458 |
| SIRT3 | sirtuin 3 | -0.00719221 |
| XIC | X chromosome inactivation center | -0.00712294 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.00704361 |
| BLNK | B-cell linker | -0.0069757 |
| CD9 | CD9 molecule | -0.00696397 |
| ADIRF | adipogenesis regulatory factor | -0.0069511 |
| MFAP3L | microfibrillar-associated protein 3-like | -0.00685507 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -0.00682812 |
| FN1 | fibronectin 1 | -0.00674598 |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 | -0.00648575 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.00606652 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | -0.00597306 |
| HOXC6 | homeobox C6 | -0.00591637 |
| GRB14 | growth factor receptor-bound protein 14 | -0.00591533 |
| ASS1 | argininosuccinate synthase 1 | -0.00588045 |
| GPRC5C | G protein-coupled receptor, class C, group 5, member C | -0.0058348 |
| KLHL9 | kelch-like family member 9 | -0.00580721 |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 | -0.00576402 |
| VNN1 | vanin 1 | -0.00571147 |
| MXRA7 | matrix-remodelling associated 7 | -0.00570051 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | -0.00569241 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.00567141 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | -0.00564119 |
| TPM2 | tropomyosin 2 (beta) | -0.00556419 |
| ENAH | enabled homolog (Drosophila) | -0.00555265 |
| REEP1 | receptor accessory protein 1 | -0.00543879 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | -0.00542398 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -0.00538305 |
| SMAD6 | SMAD family member 6 | -0.00537796 |
| PDE10A | phosphodiesterase 10A | -0.00531653 |
| STATH | statherin | -0.00529831 |
| HOXC10 | homeobox C10 | -0.0052791 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.00524758 |
| ABHD4 | abhydrolase domain containing 4 | -0.00521442 |
| BEX1 | brain expressed, X-linked 1 | -0.00520353 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | -0.00520139 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | -0.00518951 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | -0.00518187 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | -0.00517977 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.00517468 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | -0.00517277 |
| ZNF652 | zinc finger protein 652 | -0.00515537 |
| FOXC1 | forkhead box C1 | -0.00508801 |
| RNASE3 | ribonuclease, RNase A family, 3 | -0.0050593 |
| S100A10 | S100 calcium binding protein A10 | -0.00505699 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | -0.0050386 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.00501837 |
| CAV2 | caveolin 2 | -0.00500353 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.00500344 |
| EPS8L2 | EPS8-like 2 | -0.00493756 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | -0.00492535 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -0.0049166 |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A | -0.00488482 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.00487601 |
| PFKP | phosphofructokinase, platelet | -0.0048673 |
| TSPAN13 | tetraspanin 13 | -0.00486709 |
| ECHDC3 | enoyl CoA hydratase domain containing 3 | -0.00481644 |
| ECM1 | extracellular matrix protein 1 | -0.00480944 |
| SNX11 | sorting nexin 11 | -0.00479836 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.00478417 |
| AMZ2 | archaelysin family metallopeptidase 2 | -0.00478318 |
| ANKRD11 | ankyrin repeat domain 11 | -0.00478174 |
| AKAP7 | A kinase (PRKA) anchor protein 7 | -0.00475935 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.00475426 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | -0.00473207 |
| VDAC1 | voltage-dependent anion channel 1 | -0.00473062 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.00471657 |
| NTS | neurotensin | -0.00470422 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | -0.00469351 |
| SLC4A1 | solute carrier family 4 (anion exchanger), member 1 (Diego blood group) | -0.00466929 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | -0.00464762 |
| GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits | -0.0045704 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00450949 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | -0.00447897 |
| NDRG1 | N-myc downstream regulated 1 | -0.0044712 |
| NLRP2 | NLR family, pyrin domain containing 2 | -0.00445351 |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 | -0.00445201 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | -0.00444925 |
| CLDN7 | claudin 7 | -0.00444393 |
| ADCY9 | adenylate cyclase 9 | -0.0043911 |
| NELL2 | NEL-like 2 (chicken) | -0.00437885 |
| FLT3 | fms-related tyrosine kinase 3 | -0.00436518 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.00435884 |
| GSTZ1 | glutathione S-transferase zeta 1 | -0.00435225 |
| RAB40B | RAB40B, member RAS oncogene family | -0.00434848 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | -0.00434065 |
| UPK1B | uroplakin 1B | -0.0043315 |
| FGF13 | fibroblast growth factor 13 | -0.00432476 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.00432332 |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa | -0.00429378 |
| COL11A1 | collagen, type XI, alpha 1 | -0.00428093 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | -0.00426026 |
| RNF141 | ring finger protein 141 | -0.00424782 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 | -0.00422535 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | -0.00421927 |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 | -0.00418784 |
| ALDH18A1 | aldehyde dehydrogenase 18 family, member A1 | -0.00417976 |
| MTA1 | metastasis associated 1 | -0.00415124 |
| MUC1 | mucin 1, cell surface associated | -0.00412538 |
| NKX3-1 | NK3 homeobox 1 | -0.00411578 |
| CXADR | coxsackie virus and adenovirus receptor | -0.00411377 |
| CA2 | carbonic anhydrase II | -0.00411065 |
| ZNF721 | zinc finger protein 721 | -0.00410794 |
| TBCA | tubulin folding cofactor A | -0.00410782 |
| EPCAM | epithelial cell adhesion molecule | -0.00410577 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.00410086 |
| SLC25A46 | solute carrier family 25, member 46 | -0.0040993 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.00409339 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 | -0.00409047 |
| COL4A5 | collagen, type IV, alpha 5 | -0.00407829 |
| FHL1 | four and a half LIM domains 1 | -0.00407461 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 | -0.00407233 |
| BCAS1 | breast carcinoma amplified sequence 1 | -0.0040679 |
| JPT1 | Jupiter microtubule associated homolog 1 | -0.00406609 |
| CNIH4 | cornichon family AMPA receptor auxiliary protein 4 | -0.00405863 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.00404972 |
| TMSB15A | thymosin beta 15a | -0.00404056 |
| TMEM63A | transmembrane protein 63A | -0.00403902 |
| TMEM255A | transmembrane protein 255A | -0.00403182 |
| TRAM1 | translocation associated membrane protein 1 | -0.00402829 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.00402654 |
| KRT7 | keratin 7, type II | -0.00402057 |
| ITM2C | integral membrane protein 2C | -0.00400817 |
| RPS27L | ribosomal protein S27-like | -0.00400711 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.00399349 |
| INHBA | inhibin, beta A | -0.00399034 |
| SCARB2 | scavenger receptor class B, member 2 | -0.00398978 |
| GRHPR | glyoxylate reductase/hydroxypyruvate reductase | -0.00398529 |
| LRRN3 | leucine rich repeat neuronal 3 | -0.0039805 |
| EHD3 | EH-domain containing 3 | -0.00397104 |
| TMEM100 | transmembrane protein 100 | -0.00396202 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | -0.00394982 |
| ATP6AP2 | ATPase, H+ transporting, lysosomal accessory protein 2 | -0.00394901 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.00394794 |
| ZNF804A | zinc finger protein 804A | -0.00394639 |
| SEC61B | Sec61 beta subunit | -0.00391504 |
| STK26 | serine/threonine protein kinase 26 | -0.00390443 |
| KLRC3 | killer cell lectin-like receptor subfamily C, member 3 | -0.00389776 |
| SLC16A4 | solute carrier family 16, member 4 | -0.00389036 |
| TGFA | transforming growth factor, alpha | -0.00388349 |
| L1CAM | L1 cell adhesion molecule | -0.00387511 |
| ZMAT3 | zinc finger, matrin-type 3 | -0.00386827 |
| S100A8 | S100 calcium binding protein A8 | -0.00386189 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.00384348 |
| HBB | hemoglobin, beta | -0.00383437 |
| OGDHL | oxoglutarate dehydrogenase-like | -0.00382122 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | -0.00381787 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0038174 |
| CTSD | cathepsin D | -0.00381063 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | -0.00380382 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | -0.00380333 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | -0.00379997 |
| C6ORF48 | chromosome 6 open reading frame 48 | -0.00379627 |
| UBE2J1 | ubiquitin-conjugating enzyme E2, J1 | -0.00378508 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | -0.0037762 |
| DYNLT1 | dynein, light chain, Tctex-type 1 | -0.00377591 |
| TM7SF2 | transmembrane 7 superfamily member 2 | -0.00377161 |
| PTGES | prostaglandin E synthase | -0.00377103 |
| MSMB | microseminoprotein, beta- | -0.00377067 |
| COCH | cochlin | -0.00376066 |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) | -0.00374544 |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) | -0.00374509 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.00374481 |
| TFF1 | trefoil factor 1 | -0.00374345 |
| SCD5 | stearoyl-CoA desaturase 5 | -0.00374009 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -0.00373946 |
| OGA | O-GlcNAcase | -0.0037303 |
| DCAF10 | DDB1 and CUL4 associated factor 10 | -0.00372714 |
| C9ORF3 | chromosome 9 open reading frame 3 | -0.00372556 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | -0.00372551 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 | -0.00371874 |
| TFEC | transcription factor EC | -0.00370445 |
| KLRK1 | killer cell lectin-like receptor subfamily K, member 1 | -0.00369987 |
| SMAD3 | SMAD family member 3 | -0.00368698 |
| SHTN1 | shootin 1 | -0.00367995 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.00367963 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.00367388 |
| PLEK | pleckstrin | -0.00367254 |
| SPRR3 | small proline-rich protein 3 | -0.00366624 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.00366587 |
| RADX | RPA1 related single stranded DNA binding protein, X-linked | -0.00365846 |
| UST | uronyl-2-sulfotransferase | -0.00365489 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | -0.00365175 |
| ACOX1 | acyl-CoA oxidase 1, palmitoyl | -0.00364758 |
| G0S2 | G0/G1 switch 2 | -0.00364567 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.00364434 |
| LMCD1 | LIM and cysteine-rich domains 1 | -0.00363717 |
| ALAS2 | 5'-aminolevulinate synthase 2 | -0.00363247 |
| CHKB | choline kinase beta | -0.00363108 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | -0.00361998 |
| EAF2 | ELL associated factor 2 | -0.00361891 |
| CFD | complement factor D (adipsin) | -0.0036155 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.0036044 |
| E2F3 | E2F transcription factor 3 | -0.0036031 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | -0.00360164 |
| PLEC | plectin | -0.00360097 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.00359265 |
| MFSD1 | major facilitator superfamily domain containing 1 | -0.00358866 |
| PRKCB | protein kinase C, beta | -0.0035828 |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa | -0.00358151 |
| ANKMY2 | ankyrin repeat and MYND domain containing 2 | -0.00357377 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent | -0.00356099 |
| TRIM22 | tripartite motif containing 22 | -0.00355804 |
| MXI1 | MAX interactor 1, dimerization protein | -0.00355742 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.00355372 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.00355234 |
| JADE3 | jade family PHD finger 3 | -0.00354798 |
| TUBB2A | tubulin, beta 2A class IIa | -0.00354013 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.00353853 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.00352467 |
| COX7A2 | cytochrome c oxidase subunit VIIa polypeptide 2 (liver) | -0.00351249 |
| CORO1C | coronin, actin binding protein, 1C | -0.00350847 |
| FBXW12 | F-box and WD repeat domain containing 12 | -0.00349792 |
| PTK2 | protein tyrosine kinase 2 | -0.00349342 |
| SCAMP1 | secretory carrier membrane protein 1 | -0.00349204 |
| XPOT | exportin, tRNA | -0.00348303 |
| C11ORF58 | chromosome 11 open reading frame 58 | -0.00347684 |
| TUBB2B | tubulin, beta 2B class IIb | -0.00347583 |
| LPPR1 | lipid phosphate phosphatase-related protein type 1 | -0.00346982 |
| SHOC2 | soc-2 suppressor of clear homolog (C. elegans) | -0.00346572 |
| WFDC1 | WAP four-disulfide core domain 1 | -0.00346508 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 | -0.00346356 |
| GLO1 | glyoxalase I | -0.00345999 |
| EPPK1 | epiplakin 1 | -0.00345883 |
| CSTA | cystatin A (stefin A) | -0.00345867 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | -0.00345438 |
| PRB3 | proline-rich protein BstNI subfamily 3 | -0.00344988 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 | -0.00344704 |
| CAB39 | calcium binding protein 39 | -0.00344495 |
| COPG1 | coatomer protein complex, subunit gamma 1 | -0.00344493 |
| SYT1 | synaptotagmin I | -0.00344323 |
| CCN2 | cellular communication network factor 2 | -0.003442 |
| HLA-E | major histocompatibility complex, class I, E | -0.00344069 |
| SCPEP1 | serine carboxypeptidase 1 | -0.00343143 |
| ELANE | elastase, neutrophil expressed | -0.00342228 |
| KRT17 | keratin 17, type I | -0.00341704 |
| UFL1 | UFM1-specific ligase 1 | -0.00340785 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | -0.0034073 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.00340684 |
| RCN2 | reticulocalbin 2, EF-hand calcium binding domain | -0.00340297 |
| NSA2 | NSA2 ribosome biogenesis homolog (S. cerevisiae) | -0.00339944 |
| CTSC | cathepsin C | -0.00339353 |
| ZNF160 | zinc finger protein 160 | -0.00338297 |
