RIPK3 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description receptor-interacting serine-threonine kinase 3|The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 11035)
External Link https://ncbi.nlm.nih.gov/gene/11035
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Genes

498 genes differentially expressed following the RIPK3 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
XIC X chromosome inactivation center 0.0156016
NIBAN1 niban apoptosis regulator 1 0.0152416
IFI27 interferon, alpha-inducible protein 27 0.014989
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.0134065
CLU clusterin 0.0127034
CCN3 cellular communication network factor 3 0.0118107
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.0118014
TFPI2 tissue factor pathway inhibitor 2 0.0114364
CRYAB crystallin, alpha B 0.0113763
TGFBR3 transforming growth factor, beta receptor III 0.0112967
PEG10 paternally expressed 10 0.0106948
IL6R interleukin 6 receptor 0.0101942
GNG11 guanine nucleotide binding protein (G protein), gamma 11 0.00959023
SGCE sarcoglycan, epsilon 0.00935881
EIF5A eukaryotic translation initiation factor 5A 0.00928586
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.00923558
GPNMB glycoprotein (transmembrane) nmb 0.0091969
ALCAM activated leukocyte cell adhesion molecule 0.00908155
SST somatostatin 0.00898559
F13A1 coagulation factor XIII, A1 polypeptide 0.00890848
SRPX sushi-repeat containing protein, X-linked 0.00890223
PTN pleiotrophin 0.00889962
DLK1 delta-like 1 homolog (Drosophila) 0.00885713
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 0.00868117
LGALS1 lectin, galactoside-binding, soluble, 1 0.00865318
FAM110B family with sequence similarity 110, member B 0.00863345
PITX3 paired-like homeodomain 3 0.00861653
STAB1 stabilin 1 0.00858408
MAGEA3 melanoma antigen family A3 0.00848661
CCNA2 cyclin A2 0.00830044
FABP4 fatty acid binding protein 4, adipocyte 0.00825497
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 0.00816253
MT1M metallothionein 1M 0.00815994
PXDC1 PX domain containing 1 0.00807475
AQP3 aquaporin 3 (Gill blood group) 0.00807472
HSPA2 heat shock 70kDa protein 2 0.00805721
MFAP3L microfibrillar-associated protein 3-like 0.00802793
TIMP1 TIMP metallopeptidase inhibitor 1 0.00801838
AMOTL2 angiomotin like 2 0.00799685
HMOX1 heme oxygenase 1 0.00795835
DEFB1 defensin, beta 1 0.00795248
CFD complement factor D (adipsin) 0.00784818
SPON2 spondin 2, extracellular matrix protein 0.0078415
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 0.00781631
RGL1 ral guanine nucleotide dissociation stimulator-like 1 0.00771724
SDCBP syndecan binding protein (syntenin) 0.00770409
GSTM3 glutathione S-transferase mu 3 (brain) 0.00755094
EMX2 empty spiracles homeobox 2 0.00750638
RIPOR2 RHO family interacting cell polarization regulator 2 0.00737925
MAGEA12 melanoma antigen family A12 0.00734643
BIK BCL2-interacting killer (apoptosis-inducing) 0.00734467
TRIB3 tribbles pseudokinase 3 0.00733634
STIP1 stress-induced phosphoprotein 1 0.00733393
MXRA7 matrix-remodelling associated 7 0.00731592
ARHGAP29 Rho GTPase activating protein 29 0.00729039
TAC1 tachykinin, precursor 1 0.00725564
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.00722188
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.00718495
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.00714752
MSX1 msh homeobox 1 0.00713261
MIR22HG MIR22 host gene 0.00712583
QSOX1 quiescin Q6 sulfhydryl oxidase 1 0.00710224
THBS1 thrombospondin 1 0.00709959
QKI QKI, KH domain containing, RNA binding 0.00708726
PLTP phospholipid transfer protein 0.00708423
TARP TCR gamma alternate reading frame protein 0.0070444
UPP1 uridine phosphorylase 1 0.00699943
WBP5 WW domain binding protein 5 0.00698472
PEA15 phosphoprotein enriched in astrocytes 15 0.0069464
HOMER3 homer scaffolding protein 3 0.00691897
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.00686659
SOCS2 suppressor of cytokine signaling 2 0.00683955
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.00682483
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 0.00682315
PIGT phosphatidylinositol glycan anchor biosynthesis, class T 0.00680312
IFI6 interferon, alpha-inducible protein 6 0.00680096
GRN granulin 0.00679727
FASTKD5 FAST kinase domains 5 0.00677454
LAPTM4B lysosomal protein transmembrane 4 beta 0.00677237
MME membrane metallo-endopeptidase 0.00676803
TENT5A terminal nucleotidyltransferase 5A 0.00675332
CD36 CD36 molecule (thrombospondin receptor) 0.00674092
VGLL4 vestigial-like family member 4 0.00673041
FOSL2 FOS-like antigen 2 0.00667678
LYPD1 LY6/PLAUR domain containing 1 0.00665743
MALT1 MALT1 paracaspase 0.00663744
SYBU syntabulin (syntaxin-interacting) 0.0066303
LAMP1 lysosomal-associated membrane protein 1 0.0066295
FBLN5 fibulin 5 0.00660291
GSK3B glycogen synthase kinase 3 beta 0.00659403
PRSS8 protease, serine, 8 0.00658778
PON2 paraoxonase 2 0.00658225
ATF3 activating transcription factor 3 0.00657672
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 0.00654273
LUM lumican 0.00647108
P2RY14 purinergic receptor P2Y, G-protein coupled, 14 0.00646762
BAD BCL2-associated agonist of cell death 0.00646539
NOTCH2 notch 2 0.00646084
FOSL1 FOS-like antigen 1 0.00645067
UBA1 ubiquitin-like modifier activating enzyme 1 0.00644888
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.00640867
TSPYL5 TSPY-like 5 0.0064046
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.00638955
COL14A1 collagen, type XIV, alpha 1 0.00625848
STK3 serine/threonine kinase 3 0.00625378
SLIT2 slit homolog 2 (Drosophila) 0.00624901
ADRA2A adrenoceptor alpha 2A 0.00624744
CAPN2 calpain 2, (m/II) large subunit 0.00624315
RAB11FIP2 RAB11 family interacting protein 2 (class I) 0.00621633
ACTN4 actinin, alpha 4 0.00621005
NOTCH2NL notch 2 N-terminal like 0.00617825
HACD2 3-hydroxyacyl-CoA dehydratase 2 0.00617324
KRT14 keratin 14, type I 0.00615843
PENK proenkephalin 0.00613627
PDGFD platelet derived growth factor D 0.00612487
SYNE1 spectrin repeat containing, nuclear envelope 1 0.00611216
SLC43A3 solute carrier family 43, member 3 0.00608162
PRAME preferentially expressed antigen in melanoma 0.00606918
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.0060636
UBE2E3 ubiquitin-conjugating enzyme E2E 3 0.00604208
IFRD1 interferon-related developmental regulator 1 0.00603305
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.00603143
ECM1 extracellular matrix protein 1 0.00603135
ATP6V0E2 ATPase, H+ transporting V0 subunit e2 0.0060182
MXI1 MAX interactor 1, dimerization protein 0.00600974
IL1R1 interleukin 1 receptor, type I 0.00598933
LAMB3 laminin, beta 3 0.00598578
HSPA1A heat shock 70kDa protein 1A 0.00598341
SNAI2 snail family zinc finger 2 0.00598253
AHR aryl hydrocarbon receptor 0.00598038
CTSA cathepsin A 0.00598008
PMP22 peripheral myelin protein 22 0.00597778
CPB1 carboxypeptidase B1 (tissue) 0.00594832
PLAT plasminogen activator, tissue 0.00592976
RCAN1 regulator of calcineurin 1 0.00590207
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 0.00587078
OXTR oxytocin receptor 0.00586936
MMP7 matrix metallopeptidase 7 0.00586596
DCLK1 doublecortin-like kinase 1 0.00585407
CLGN calmegin 0.00585342
NCOA1 nuclear receptor coactivator 1 0.00584972
MYH9 myosin, heavy chain 9, non-muscle 0.00584526
SLC38A1 solute carrier family 38, member 1 0.00583359
APLP2 amyloid beta (A4) precursor-like protein 2 0.00581825
PGAM1 phosphoglycerate mutase 1 (brain) 0.0058145
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 0.00581028
FADS3 fatty acid desaturase 3 0.00580033
TMBIM6 transmembrane BAX inhibitor motif containing 6 0.00579346
NPY1R neuropeptide Y receptor Y1 0.00579095
JMJD6 jumonji domain containing 6 0.00578613
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 0.0057802
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.00576048
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B 0.00574596
CLEC3B C-type lectin domain family 3, member B 0.0057303
ASNS asparagine synthetase (glutamine-hydrolyzing) 0.00571874
CA2 carbonic anhydrase II 0.00569502
S100A2 S100 calcium binding protein A2 0.00567997
ZEB2 zinc finger E-box binding homeobox 2 0.00565892
RNF167 ring finger protein 167 0.00565379
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 0.00560911
SQSTM1 sequestosome 1 0.0056017
HOMER1 homer scaffolding protein 1 0.00560082
KRT7 keratin 7, type II 0.00556363
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.00556088
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 0.00555753
AXL AXL receptor tyrosine kinase 0.00555376
C1QB complement component 1, q subcomponent, B chain 0.00552956
TNNC1 troponin C type 1 (slow) 0.00552729
HEATR1 HEAT repeat containing 1 0.00552559
ANK2 ankyrin 2, neuronal 0.00551454
TCL1A T-cell leukemia/lymphoma 1A 0.00549698
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.00546704
FKBP9 FK506 binding protein 9, 63 kDa 0.00546386
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 0.00545948
CLEC2B C-type lectin domain family 2, member B 0.00545862
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.00545397
CMTM6 CKLF-like MARVEL transmembrane domain containing 6 0.00545149
PEG3 paternally expressed 3 0.00544118
CCDC86 coiled-coil domain containing 86 0.0054195
MAGED1 melanoma antigen family D1 0.00541428
PPIF peptidylprolyl isomerase F 0.00541244
CYB5R1 cytochrome b5 reductase 1 0.0054081
RUNX3 runt-related transcription factor 3 0.00540369
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 0.00539536
CALCA calcitonin-related polypeptide alpha 0.00538493
PLD3 phospholipase D family, member 3 0.00538359
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 0.00538182
LAMP2 lysosomal-associated membrane protein 2 0.0053795
ZNHIT6 zinc finger, HIT-type containing 6 0.00535473
LPIN1 lipin 1 0.00534986
TNNT1 troponin T type 1 (skeletal, slow) 0.00534681
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 0.00533929
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 0.00531691
CXCL12 chemokine (C-X-C motif) ligand 12 0.00530855
EMP1 epithelial membrane protein 1 0.00530773
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 0.00530306
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 0.00527807
GNG5 guanine nucleotide binding protein (G protein), gamma 5 0.00527654
TP53BP2 tumor protein p53 binding protein 2 0.00527324
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.0052647
KRT5 keratin 5, type II 0.00525073
MRPS28 mitochondrial ribosomal protein S28 0.00524802
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 0.00524349
PDE2A phosphodiesterase 2A, cGMP-stimulated 0.00524277
ADGRG2 adhesion G protein-coupled receptor G2 0.00524145
GLIPR1 GLI pathogenesis-related 1 0.00523935
ELAPOR1 endosome-lysosome associated apoptosis and autophagy regulator 1 0.00522691
RRAGC Ras-related GTP binding C 0.00522677
EGR3 early growth response 3 0.00522283
SGPL1 sphingosine-1-phosphate lyase 1 0.00522215
KRT18 keratin 18, type I 0.0052167
CPM carboxypeptidase M 0.00520423
KLF6 Kruppel-like factor 6 0.0051998
TMEM100 transmembrane protein 100 0.005192
RUBCN rubicon autophagy regulator 0.00516816
ACTN1 actinin, alpha 1 0.00515679
BCAT2 branched chain amino-acid transaminase 2, mitochondrial 0.00513535
COX6C cytochrome c oxidase subunit VIc 0.00513528
BANF1 barrier to autointegration factor 1 0.00513289
AREG amphiregulin 0.00512427
FOLR1 folate receptor 1 (adult) 0.0051165
PFN2 profilin 2 0.00511341
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 0.00508008
LAMB2 laminin, beta 2 (laminin S) 0.00507189
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.0050692
KLHL21 kelch-like family member 21 0.00506105
MAGEA1 melanoma antigen family A1 0.00505875
GADD45A growth arrest and DNA-damage-inducible, alpha 0.00505609
STC2 stanniocalcin 2 0.00504306
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.00504036
SERHL2 serine hydrolase-like 2 0.00503992
PPP1R3C protein phosphatase 1, regulatory subunit 3C 0.00503808
GLDC glycine dehydrogenase (decarboxylating) 0.00502723
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.00501585
MBL2 mannose-binding lectin (protein C) 2, soluble 0.00501102
TP73-AS1 TP73 antisense RNA 1 0.00500858
FAM13B family with sequence similarity 13, member B 0.00500699
EMP3 epithelial membrane protein 3 0.00500483
JAG1 jagged 1 0.00498769
FGF13 fibroblast growth factor 13 0.00498436
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.00498268
AZGP1 alpha-2-glycoprotein 1, zinc-binding 0.00498204
SASH1 SAM and SH3 domain containing 1 0.00497254
FGFR1 fibroblast growth factor receptor 1 0.00493558
TMBIM1 transmembrane BAX inhibitor motif containing 1 0.00493207
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.0049243
PSAP prosaposin 0.00492293
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) 0.00491789
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.00487972

decreased expression

Symbol Name Standardized Value
PCNA proliferating cell nuclear antigen -0.0300671
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.018056
OXA1L oxidase (cytochrome c) assembly 1-like -0.0158822
LTF lactotransferrin -0.012845
S100A8 S100 calcium binding protein A8 -0.0126031
TFF1 trefoil factor 1 -0.0116811
NTS neurotensin -0.0111326
S100A9 S100 calcium binding protein A9 -0.0108987
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 -0.0108606
KDM5D lysine (K)-specific demethylase 5D -0.0101914
PBX1 pre-B-cell leukemia homeobox 1 -0.0101124
RGS10 regulator of G-protein signaling 10 -0.00980137
SCD5 stearoyl-CoA desaturase 5 -0.00951201
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 -0.00948959
CXCL5 chemokine (C-X-C motif) ligand 5 -0.00941615
TMSB15A thymosin beta 15a -0.00938311
SNX5 sorting nexin 5 -0.00935105
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.00926018
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 -0.00921378
PCLAF PCNA clamp associated factor -0.00915786
ELP1 elongator acetyltransferase complex subunit 1 -0.00909018
LMO3 LIM domain only 3 (rhombotin-like 2) -0.00905787
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -0.0089731
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial -0.00878865
LTA4H leukotriene A4 hydrolase -0.00878179
TMEM230 transmembrane protein 230 -0.00871408
TESC tescalcin -0.00861674
CA12 carbonic anhydrase XII -0.00858736
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 -0.00858204
PTCH1 patched 1 -0.00857267
TYMS thymidylate synthetase -0.00857155
PWP1 PWP1 homolog (S. cerevisiae) -0.00846009
FERMT1 fermitin family member 1 -0.00823735
S100A7 S100 calcium binding protein A7 -0.00805524
PLN phospholamban -0.00790594
DERA deoxyribose-phosphate aldolase (putative) -0.00789952
ACOT13 acyl-CoA thioesterase 13 -0.00789533
MGP matrix Gla protein -0.00780312
IGBP1 immunoglobulin (CD79A) binding protein 1 -0.00766585
S100A12 S100 calcium binding protein A12 -0.00757369
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 -0.00755206
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -0.00753888
NREP neuronal regeneration related protein -0.00749451
SFTPB surfactant protein B -0.00746349
MCM6 minichromosome maintenance complex component 6 -0.00745209
IVNS1ABP influenza virus NS1A binding protein -0.00732402
NPR3 natriuretic peptide receptor 3 -0.00731521
TIA1 TIA1 cytotoxic granule-associated RNA binding protein -0.00724183
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 -0.00712448
NID2 nidogen 2 (osteonidogen) -0.00700973
CHD9 chromodomain helicase DNA binding protein 9 -0.00693644
ATP11B ATPase, class VI, type 11B -0.00690953
TRAPPC3 trafficking protein particle complex 3 -0.00690774
MMP12 matrix metallopeptidase 12 -0.00690643
TM4SF4 transmembrane 4 L six family member 4 -0.00686055
MUC5AC mucin 5AC, oligomeric mucus/gel-forming -0.00684666
F5 coagulation factor V (proaccelerin, labile factor) -0.00682547
EPB41L4B erythrocyte membrane protein band 4.1 like 4B -0.00681748
FZD7 frizzled class receptor 7 -0.00678658
CD38 CD38 molecule -0.00678253
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 -0.00676584
OLFM1 olfactomedin 1 -0.0067141
GINS2 GINS complex subunit 2 (Psf2 homolog) -0.00668427
PLCB4 phospholipase C, beta 4 -0.00662859
MECOM MDS1 and EVI1 complex locus -0.00659045
RAD23B RAD23 homolog B (S. cerevisiae) -0.00656861
CEMIP cell migration inducing protein, hyaluronan binding -0.00655412
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.00652192
COMMD3 COMM domain containing 3 -0.00652125
ERAP2 endoplasmic reticulum aminopeptidase 2 -0.00650337
GJA1 gap junction protein, alpha 1, 43kDa -0.00644419
MUC5B mucin 5B, oligomeric mucus/gel-forming -0.00643864
ISOC1 isochorismatase domain containing 1 -0.00643315
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 -0.00639845
SEPHS1 selenophosphate synthetase 1 -0.00638483
GSE1 Gse1 coiled-coil protein -0.00636145
NMRK1 nicotinamide riboside kinase 1 -0.00633032
DMBT1 deleted in malignant brain tumors 1 -0.00631505
TMEM38B transmembrane protein 38B -0.00627792
METAP2 methionyl aminopeptidase 2 -0.0062641
CDKN2A cyclin-dependent kinase inhibitor 2A -0.00625315
NEBL nebulette -0.00624812
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 -0.00622594
NFE2L3 nuclear factor, erythroid 2-like 3 -0.00621984
SLPI secretory leukocyte peptidase inhibitor -0.0062014
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 -0.00619932
RPL35 ribosomal protein L35 -0.00619095
SNRPA small nuclear ribonucleoprotein polypeptide A -0.00618951
MPZL2 myelin protein zero-like 2 -0.00618186
EIF4B eukaryotic translation initiation factor 4B -0.00618183
C9ORF3 chromosome 9 open reading frame 3 -0.00617203
RPL14 ribosomal protein L14 -0.00615253
FXYD3 FXYD domain containing ion transport regulator 3 -0.00614288
SFTPA2 surfactant protein A2 -0.00609056
VSNL1 visinin-like 1 -0.0060641
HAUS4 HAUS augmin-like complex, subunit 4 -0.00605691
CDT1 chromatin licensing and DNA replication factor 1 -0.00604807
NQO2 NAD(P)H dehydrogenase, quinone 2 -0.00604779
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 -0.00602222
LXN latexin -0.00601373
RAI14 retinoic acid induced 14 -0.006005
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 -0.00599613
PON3 paraoxonase 3 -0.0059781
POSTN periostin, osteoblast specific factor -0.00597689
GPX2 glutathione peroxidase 2 -0.0059675
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3 -0.00595885
CLNS1A chloride channel, nucleotide-sensitive, 1A -0.00594052
RGCC regulator of cell cycle -0.00592205
EEF2 eukaryotic translation elongation factor 2 -0.00590833
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) -0.00590467
C6ORF48 chromosome 6 open reading frame 48 -0.00588853
ZMYM2 zinc finger, MYM-type 2 -0.00588302
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 -0.0058719
LETMD1 LETM1 domain containing 1 -0.00583176
IPO7 importin 7 -0.00583143
ACTG2 actin, gamma 2, smooth muscle, enteric -0.00578544
BCAS3 breast carcinoma amplified sequence 3 -0.00577795
GTF3A general transcription factor IIIA -0.00572526
CADPS2 Ca++-dependent secretion activator 2 -0.00572519
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -0.00571206
RBMX RNA binding motif protein, X-linked -0.00570316
DHRS3 dehydrogenase/reductase (SDR family) member 3 -0.00565402
NUP85 nucleoporin 85kDa -0.00564526
EHBP1 EH domain binding protein 1 -0.0056402
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) -0.00562808
TARBP1 TAR (HIV-1) RNA binding protein 1 -0.00560158
INSM1 insulinoma-associated 1 -0.00558908
GAL galanin/GMAP prepropeptide -0.00558084
GNAQ guanine nucleotide binding protein (G protein), q polypeptide -0.00557915
RXYLT1 ribitol xylosyltransferase 1 -0.00556414
CHGB chromogranin B -0.00555577
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 -0.00555052
HLA-DOB major histocompatibility complex, class II, DO beta -0.00551724
TSHR thyroid stimulating hormone receptor -0.00549448
PRC1 protein regulator of cytokinesis 1 -0.00548839
MRPS27 mitochondrial ribosomal protein S27 -0.00547573
OCRL oculocerebrorenal syndrome of Lowe -0.00544401
NCK1 NCK adaptor protein 1 -0.00543916
EML4 echinoderm microtubule associated protein like 4 -0.00543143
RBBP4 retinoblastoma binding protein 4 -0.00540381
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 -0.00539847
ESD esterase D -0.00537863
HIST3H2A histone cluster 3, H2a -0.00537756
BPHL biphenyl hydrolase-like (serine hydrolase) -0.00536745
CDH17 cadherin 17, LI cadherin (liver-intestine) -0.00536745
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.00536601
C14ORF132 chromosome 14 open reading frame 132 -0.00536581
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 -0.00536177
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -0.00536131
ELP4 elongator acetyltransferase complex subunit 4 -0.0053611
SLCO4A1 solute carrier organic anion transporter family, member 4A1 -0.00535037
MCM2 minichromosome maintenance complex component 2 -0.00533744
TRIM2 tripartite motif containing 2 -0.0053272
SPRED2 sprouty-related, EVH1 domain containing 2 -0.00532122
ARMCX2 armadillo repeat containing, X-linked 2 -0.00530816
ZNF423 zinc finger protein 423 -0.00530027
FA2H fatty acid 2-hydroxylase -0.00529912
NME4 NME/NM23 nucleoside diphosphate kinase 4 -0.00528976
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) -0.00528434
HMGB2 high mobility group box 2 -0.00528212
PXMP2 peroxisomal membrane protein 2, 22kDa -0.00528153
POLR1D polymerase (RNA) I polypeptide D, 16kDa -0.00525832
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 -0.00523814
TLK2 tousled-like kinase 2 -0.0052139
ZNF277 zinc finger protein 277 -0.00520788
CD200 CD200 molecule -0.00520578
DHTKD1 dehydrogenase E1 and transketolase domain containing 1 -0.00518197
LAMA4 laminin, alpha 4 -0.00518062
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 -0.00517101
AGTR1 angiotensin II receptor, type 1 -0.00517051
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -0.00516003
SH3YL1 SH3 and SYLF domain containing 1 -0.00515203
TRIB2 tribbles pseudokinase 2 -0.00511927
PDLIM3 PDZ and LIM domain 3 -0.00511584
KLHL23 kelch-like family member 23 -0.00510541
BEX1 brain expressed, X-linked 1 -0.00509865
PLK1 polo-like kinase 1 -0.00509454
FDX1 ferredoxin 1 -0.00509375
TPSAB1 tryptase alpha/beta 1 -0.00506761
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.00505581
C3ORF14 chromosome 3 open reading frame 14 -0.005046
AUH AU RNA binding protein/enoyl-CoA hydratase -0.00504341
LMNB1 lamin B1 -0.00502993
DPH5 diphthamide biosynthesis 5 -0.00501734
ZNF204P zinc finger protein 204, pseudogene -0.0049901
NUP37 nucleoporin 37kDa -0.00498493
SDC2 syndecan 2 -0.00498482
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -0.00497591
WNT5A wingless-type MMTV integration site family, member 5A -0.00497161
AKAP1 A kinase (PRKA) anchor protein 1 -0.00493784
CNN1 calponin 1, basic, smooth muscle -0.00492539
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) -0.00492008
ASMTL acetylserotonin O-methyltransferase-like -0.00490793
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 -0.00488179
CETN2 centrin, EF-hand protein, 2 -0.00487119
HOPX HOP homeobox -0.00484746
NCBP1 nuclear cap binding protein subunit 1, 80kDa -0.00483834
EIF3E eukaryotic translation initiation factor 3, subunit E -0.00483593
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase -0.00482007
RAB40B RAB40B, member RAS oncogene family -0.00481891
UQCRC2 ubiquinol-cytochrome c reductase core protein II -0.0048171
CRNKL1 crooked neck pre-mRNA splicing factor 1 -0.00481473
C2CD5 C2 calcium-dependent domain containing 5 -0.00481446
HIGD2A HIG1 hypoxia inducible domain family, member 2A -0.00479993
POU2AF1 POU class 2 associating factor 1 -0.00478598
KIF20A kinesin family member 20A -0.00477909
ACAA2 acetyl-CoA acyltransferase 2 -0.00477118
CTSE cathepsin E -0.00476312
FBXW2 F-box and WD repeat domain containing 2 -0.00475933
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 -0.004752
TFF3 trefoil factor 3 (intestinal) -0.00474987
ANG angiogenin, ribonuclease, RNase A family, 5 -0.00473904
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 -0.00473343
RPL13 ribosomal protein L13 -0.00472674
KIF15 kinesin family member 15 -0.00471148
CD1A CD1a molecule -0.00471091
GRIA2 glutamate receptor, ionotropic, AMPA 2 -0.00470948
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.00469106
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 -0.00468175
UFSP2 UFM1-specific peptidase 2 -0.00468141
GSAP gamma-secretase activating protein -0.00467538
ABHD17B abhydrolase domain containing 17B -0.00466956
TUBD1 tubulin, delta 1 -0.00466814
CD48 CD48 molecule -0.00464964
MARCKSL1 MARCKS-like 1 -0.00463583
RPS8 ribosomal protein S8 -0.00463294
PLEK2 pleckstrin 2 -0.00462483
GYPC glycophorin C (Gerbich blood group) -0.00462401
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 -0.00462169
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 -0.00462157
AKT3 v-akt murine thymoma viral oncogene homolog 3 -0.00462125
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase -0.00461511
DHPS deoxyhypusine synthase -0.00461407
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) -0.0046126
KNTC1 kinetochore associated 1 -0.00460758
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) -0.00459321
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 -0.00457417
PAGE4 P antigen family, member 4 (prostate associated) -0.00457158
FOXF1 forkhead box F1 -0.00456616
MRPS18B mitochondrial ribosomal protein S18B -0.00456039
RPL10 ribosomal protein L10 -0.00455627
DEPTOR DEP domain containing MTOR-interacting protein -0.00455422
ACOX2 acyl-CoA oxidase 2, branched chain -0.00455088
ENOPH1 enolase-phosphatase 1 -0.00455074
ZMYM3 zinc finger, MYM-type 3 -0.00454687
TNC tenascin C -0.00454564
CBX5 chromobox homolog 5 -0.00454186
NDNF neuron-derived neurotrophic factor -0.00453384
SLC26A4 solute carrier family 26 (anion exchanger), member 4 -0.00452471