RIPK3 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description receptor-interacting serine-threonine kinase 3|The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 11035)
External Link http://www.ncbi.nlm.nih.gov/gene/11035
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112 interacting proteins for RIPK3 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ACTG1 actin gamma 1
ACTN4 actinin, alpha 4
AIF1L allograft inflammatory factor 1-like
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
ATAD3A ATPase family, AAA domain containing 3A
BASP1 brain abundant, membrane attached signal protein 1
BIRC2 baculoviral IAP repeat containing 2
BIRC3 baculoviral IAP repeat containing 3
C1QBP complement component 1, q subcomponent binding protein
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1
CAPZB capping protein (actin filament) muscle Z-line, beta
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CCT5 chaperonin containing TCP1, subunit 5 (epsilon)
CCT7 chaperonin containing TCP1, subunit 7 (eta)
CD14 CD14 molecule
CDC37 cell division cycle 37
CHUK conserved helix-loop-helix ubiquitous kinase
CLTC clathrin, heavy chain (Hc)
CORO1C coronin, actin binding protein, 1C
CTNND1 catenin (cadherin-associated protein), delta 1
DAPK1 death-associated protein kinase 1
DBN1 drebrin 1
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EPRS glutamyl-prolyl-tRNA synthetase
FADD Fas (TNFRSF6)-associated via death domain
FKBP4 FK506 binding protein 4, 59kDa
FKBP5 FK506 binding protein 5
FLNA filamin A, alpha
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2
GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4
GNG12 guanine nucleotide binding protein (G protein), gamma 12
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA1B heat shock 70kDa protein 1B
HSPA1L heat shock 70kDa protein 1-like
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA8 heat shock 70kDa protein 8
HSPA9 heat shock 70kDa protein 9 (mortalin)
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
INPP5K inositol polyphosphate-5-phosphatase K
IQGAP1 IQ motif containing GTPase activating protein 1
LIMA1 LIM domain and actin binding 1
LY96 lymphocyte antigen 96
MLKL mixed lineage kinase domain-like
MPRIP myosin phosphatase Rho interacting protein
MYH10 myosin, heavy chain 10, non-muscle
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle
MYO1B myosin IB
MYO1C myosin IC
MYO1D myosin ID
MYO6 myosin VI
NONO non-POU domain containing, octamer-binding
PGAM5 phosphoglycerate mutase family member 5
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP1R9B protein phosphatase 1, regulatory subunit 9B
PRDX1 peroxiredoxin 1
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PYGL phosphorylase, glycogen, liver
RAI14 retinoic acid induced 14
RFX6 regulatory factor X, 6
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RPL23 ribosomal protein L23
RPS27 ribosomal protein S27
RUVBL1 RuvB-like AAA ATPase 1
RUVBL2 RuvB-like AAA ATPase 2
SCIN scinderin
SIRT2 sirtuin 2
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like
SPTAN1 spectrin, alpha, non-erythrocytic 1
SPTBN1 spectrin, beta, non-erythrocytic 1
STIP1 stress-induced phosphoprotein 1
TIAF1 TGFB1-induced anti-apoptotic factor 1
TICAM1 toll-like receptor adaptor molecule 1
TICAM2 toll-like receptor adaptor molecule 2
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TPM1 tropomyosin 1 (alpha)
TPM3 tropomyosin 3
TRAF2 TNF receptor-associated factor 2
TUBA3C tubulin, alpha 3c
TUBB tubulin, beta class I
TUBB2B tubulin, beta 2B class IIb
TUBB4A tubulin, beta 4A class IVa
UBB ubiquitin B
UBC ubiquitin C
UBE2D1 ubiquitin-conjugating enzyme E2D 1
VIM vimentin
WDR61 WD repeat domain 61
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
ZBP1 Z-DNA binding protein 1