RIPK3 Gene Set

Dataset PhosphoSitePlus Substrates of Kinases
Category physical interactions
Type kinase
Description receptor-interacting serine-threonine kinase 3|The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 11035)
External Link http://www.ncbi.nlm.nih.gov/gene/11035
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Genes

2 substrates of the kinase RIPK3 from the curated PhosphoSitePlus Substrates of Kinases dataset.

Symbol Name
DAXX death-domain associated protein
MLKL mixed lineage kinase domain-like