| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | RMC-6236 perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the RMC-6236_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.0747391 |
| VIM | vimentin | 0.0738602 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0696815 |
| TMSB4X | thymosin beta 4, X-linked | 0.0629817 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0518843 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0427837 |
| RACK1 | receptor for activated C kinase 1 | 0.0348848 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0343459 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0337805 |
| HSPA8 | heat shock 70kDa protein 8 | 0.033637 |
| MYOF | myoferlin | 0.0328268 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0318787 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0314471 |
| RPS2 | ribosomal protein S2 | 0.0303678 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0299721 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0296253 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0287806 |
| VEGFA | vascular endothelial growth factor A | 0.0283212 |
| FN1 | fibronectin 1 | 0.0274039 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0270707 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0265438 |
| PCDH7 | protocadherin 7 | 0.0259603 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0237145 |
| SFTPA2 | surfactant protein A2 | 0.0234574 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0229924 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0227898 |
| EXT1 | exostosin glycosyltransferase 1 | 0.021906 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0213889 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0209654 |
| ASPH | aspartate beta-hydroxylase | 0.0200692 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0184473 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0169386 |
| RND3 | Rho family GTPase 3 | 0.0168768 |
| RPL3 | ribosomal protein L3 | 0.0167884 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0167253 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0165323 |
| TLN1 | talin 1 | 0.0163666 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | 0.0162141 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.016046 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0160224 |
| SET | SET nuclear proto-oncogene | 0.0152099 |
| FRMD6 | FERM domain containing 6 | 0.0150971 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0150868 |
| RPL7 | ribosomal protein L7 | 0.0150371 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0150121 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.014975 |
| RAI1 | retinoic acid induced 1 | 0.0149027 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.0143784 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0143382 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0142915 |
| AHNAK | AHNAK nucleoprotein | 0.0142619 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0141103 |
| ARRDC3 | arrestin domain containing 3 | 0.0137848 |
| KLF6 | Kruppel-like factor 6 | 0.0137458 |
| PDE10A | phosphodiesterase 10A | 0.0136976 |
| ATF4 | activating transcription factor 4 | 0.0136725 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0136274 |
| FLNA | filamin A, alpha | 0.0134902 |
| RPL27 | ribosomal protein L27 | 0.0131112 |
| EFNA5 | ephrin-A5 | 0.0128694 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.012735 |
| IER2 | immediate early response 2 | 0.0126716 |
| SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 | 0.0125607 |
| MALSU1 | mitochondrial assembly of ribosomal large subunit 1 | 0.0124499 |
| PCBP2 | poly(rC) binding protein 2 | 0.0124391 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0122253 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0122053 |
| IGF2 | insulin-like growth factor 2 | 0.0121258 |
| B2M | beta-2-microglobulin | 0.0120131 |
| PDLIM5 | PDZ and LIM domain 5 | 0.012013 |
| RPL12 | ribosomal protein L12 | 0.012005 |
| ADM | adrenomedullin | 0.0119158 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | 0.0118671 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like | 0.011802 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0117652 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0115766 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0113859 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0112427 |
| JUN | jun proto-oncogene | 0.0112023 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0111595 |
| RPS18 | ribosomal protein S18 | 0.0111362 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0110747 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.01107 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0110527 |
| CCSAP | centriole, cilia and spindle-associated protein | 0.0110416 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.011029 |
| BRD2 | bromodomain containing 2 | 0.0110174 |
| INTS6 | integrator complex subunit 6 | 0.0109708 |
| NCAPG | non-SMC condensin I complex, subunit G | 0.0109693 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0109394 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0108576 |
| RPS7 | ribosomal protein S7 | 0.0107936 |
| H4C15 | H4 clustered histone 15 | 0.0107594 |
| RPS4X | ribosomal protein S4, X-linked | 0.0105174 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0105158 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0104581 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0104556 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0103968 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0103014 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0102563 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PEG10 | paternally expressed 10 | -0.137372 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0912699 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0895286 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0888663 |
| ZNF292 | zinc finger protein 292 | -0.0822621 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0813508 |
| TPK1 | thiamin pyrophosphokinase 1 | -0.0760551 |
| NFIB | nuclear factor I/B | -0.075041 |
| MED13L | mediator complex subunit 13-like | -0.0729366 |
| QKI | QKI, KH domain containing, RNA binding | -0.0646103 |
| MEOX2 | mesenchyme homeobox 2 | -0.0610356 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0606274 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0588294 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0572841 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0572775 |
| MGP | matrix Gla protein | -0.0565004 |
| NFIA | nuclear factor I/A | -0.0537148 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0528461 |
| RHEB | Ras homolog enriched in brain | -0.0499867 |
| KAZN | kazrin, periplakin interacting protein | -0.0490628 |
| JMJD1C | jumonji domain containing 1C | -0.0490537 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0478375 |
| NBEA | neurobeachin | -0.0471728 |
| FNDC3B | fibronectin type III domain containing 3B | -0.047171 |
| SBF2 | SET binding factor 2 | -0.0468099 |
| PDGFC | platelet derived growth factor C | -0.0463245 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0462674 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0435664 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | -0.043537 |
| SEPTIN11 | septin 11 | -0.0424586 |
| ZFHX3 | zinc finger homeobox 3 | -0.0423829 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0418687 |
| GOLGA4 | golgin A4 | -0.0413341 |
| SRPK2 | SRSF protein kinase 2 | -0.0411645 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0409556 |
| AFF4 | AF4/FMR2 family, member 4 | -0.040063 |
| PTMA | prothymosin, alpha | -0.039982 |
| TET1 | tet methylcytosine dioxygenase 1 | -0.039527 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0381899 |
| CADM2 | cell adhesion molecule 2 | -0.0377969 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0377289 |
| ERBIN | erbb2 interacting protein | -0.037622 |
| PARD3 | par-3 family cell polarity regulator | -0.0369487 |
| ENAH | enabled homolog (Drosophila) | -0.0368183 |
| SMYD3 | SET and MYND domain containing 3 | -0.0366204 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.0365918 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0359129 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0356659 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0344866 |
| RANBP17 | RAN binding protein 17 | -0.0342056 |
| PCM1 | pericentriolar material 1 | -0.0327658 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0324853 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.0318224 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0317059 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0312443 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0311801 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0308638 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0308426 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.030786 |
| ACACA | acetyl-CoA carboxylase alpha | -0.029879 |
| SPPL3 | signal peptide peptidase like 3 | -0.0293053 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.0286568 |
| MEST | mesoderm specific transcript | -0.0286143 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0283479 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0282744 |
| BMPR1A | bone morphogenetic protein receptor, type IA | -0.0280586 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0278133 |
| ANKRD11 | ankyrin repeat domain 11 | -0.027772 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0273977 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.02735 |
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 | -0.0271501 |
| PHIP | pleckstrin homology domain interacting protein | -0.0268726 |
| CCSER2 | coiled-coil serine-rich protein 2 | -0.0264141 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0262887 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0262449 |
| IGF2R | insulin-like growth factor 2 receptor | -0.0262259 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0261678 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0260351 |
| OGA | O-GlcNAcase | -0.0258172 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0256974 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | -0.0255889 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0254971 |
| DIPK2A | divergent protein kinase domain 2A | -0.0254048 |
| SH3RF1 | SH3 domain containing ring finger 1 | -0.0251021 |
| PGK1 | phosphoglycerate kinase 1 | -0.0250731 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0247569 |
| PTK2 | protein tyrosine kinase 2 | -0.0245305 |
| MICU1 | mitochondrial calcium uptake 1 | -0.0245054 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0244757 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0244011 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0243942 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0243743 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.024325 |
| DENND4C | DENN/MADD domain containing 4C | -0.0243236 |
| FNIP1 | folliculin interacting protein 1 | -0.0243158 |
| POU2F1 | POU class 2 homeobox 1 | -0.0242908 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | -0.0242219 |
| GNG2 | guanine nucleotide binding protein (G protein), gamma 2 | -0.0241814 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.02418 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.0241391 |
