| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | RMC-6236 perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the RMC-6236_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.210439 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.192725 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0898785 |
| EXT1 | exostosin glycosyltransferase 1 | 0.08733 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0845556 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0768975 |
| LAMB3 | laminin, beta 3 | 0.0753 |
| EFNA5 | ephrin-A5 | 0.0721473 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0631116 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0622978 |
| PMM2 | phosphomannomutase 2 | 0.0611995 |
| SACK1A | scaffolding CK1 anchoring protein A | 0.0597567 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0579831 |
| TXNRD1 | thioredoxin reductase 1 | 0.0513325 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0509958 |
| BMP6 | bone morphogenetic protein 6 | 0.0496569 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0474452 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0425583 |
| FMNL2 | formin-like 2 | 0.042426 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0422522 |
| EGFR | epidermal growth factor receptor | 0.0421219 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0418775 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0418048 |
| DSPP | dentin sialophosphoprotein | 0.040158 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0401493 |
| GDA | guanine deaminase | 0.0396648 |
| MMP1 | matrix metallopeptidase 1 | 0.0391927 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0382567 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.037027 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0368057 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0350644 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0350416 |
| PLEC | plectin | 0.0347776 |
| B2M | beta-2-microglobulin | 0.0337851 |
| SEPTIN9 | septin 9 | 0.0337776 |
| TXNIP | thioredoxin interacting protein | 0.0332194 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0331525 |
| TGM2 | transglutaminase 2 | 0.0326714 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.031645 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0312074 |
| SP100 | SP100 nuclear antigen | 0.0307466 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0306373 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0305551 |
| SGMS2 | sphingomyelin synthase 2 | 0.0304605 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0304086 |
| OSMR | oncostatin M receptor | 0.029722 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0294782 |
| TLN1 | talin 1 | 0.0292386 |
| CLMP | CXADR-like membrane protein | 0.0290379 |
| DIAPH1 | diaphanous-related formin 1 | 0.0289078 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0285551 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0284774 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.027136 |
| GTDC1 | glycosyltransferase-like domain containing 1 | 0.0268398 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0264843 |
| HMGA2 | high mobility group AT-hook 2 | 0.0260704 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0260515 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0259208 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0256235 |
| SIK3 | SIK family kinase 3 | 0.0255958 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0245786 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0245615 |
| FLNA | filamin A, alpha | 0.023803 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0235992 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | 0.0234402 |
| SON | SON DNA binding protein | 0.0230925 |
| SMAD3 | SMAD family member 3 | 0.0229916 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | 0.0225723 |
| RPS2 | ribosomal protein S2 | 0.022514 |
| AHR | aryl hydrocarbon receptor | 0.0221971 |
| MSN | moesin | 0.0221359 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0220877 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0219028 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0217266 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0215339 |
| TPM3 | tropomyosin 3 | 0.0215097 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0214282 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0212323 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0206008 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0205145 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.020453 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0201967 |
| LCN2 | lipocalin 2 | 0.0201655 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0198789 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0195643 |
| RASAL2 | RAS protein activator like 2 | 0.0194865 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0194395 |
| EFNB2 | ephrin-B2 | 0.0193775 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0192169 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.0191015 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0189738 |
| RAI14 | retinoic acid induced 14 | 0.0189023 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0188492 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0187899 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0187878 |
| CD44 | CD44 molecule (Indian blood group) | 0.0186497 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.018513 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0185078 |
| TMC5 | transmembrane channel-like 5 | 0.0182987 |
| INTS6 | integrator complex subunit 6 | 0.0182576 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.169272 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.16628 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.159114 |
| POTEF | POTE ankyrin domain family, member F | -0.133586 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.130359 |
| PTMA | prothymosin, alpha | -0.116894 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.112399 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0986976 |
| S100A10 | S100 calcium binding protein A10 | -0.0977705 |
| HMGA1 | high mobility group AT-hook 1 | -0.0918603 |
| MUC17 | mucin 17, cell surface associated | -0.0865063 |
| LMO7 | LIM domain 7 | -0.086422 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0847407 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.0815823 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0815514 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0717641 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0694713 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0694613 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0669589 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0669153 |
| ACTG1 | actin gamma 1 | -0.0666307 |
| ITGA6 | integrin, alpha 6 | -0.065501 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.0654828 |
| SPAG9 | sperm associated antigen 9 | -0.0648445 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0645179 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0617132 |
| S100A4 | S100 calcium binding protein A4 | -0.0610207 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0610165 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0583071 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -0.0581652 |
| PERP | PERP, TP53 apoptosis effector | -0.0558704 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0557068 |
| RIOK3 | RIO kinase 3 | -0.0554919 |
| WASF2 | WAS protein family, member 2 | -0.0553811 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0526772 |
| EMP1 | epithelial membrane protein 1 | -0.0522446 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0516039 |
| VIM | vimentin | -0.0513942 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0508273 |
| EGR1 | early growth response 1 | -0.0507453 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0499883 |
| S100A6 | S100 calcium binding protein A6 | -0.0489595 |
| EZR | ezrin | -0.048154 |
| RTN4 | reticulon 4 | -0.0477467 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0469058 |
| MXD1 | MAX dimerization protein 1 | -0.0462638 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0461618 |
| FLNB | filamin B, beta | -0.045649 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0454954 |
| CD2AP | CD2-associated protein | -0.0454902 |
| FOSL1 | FOS-like antigen 1 | -0.04494 |
| GNAS | GNAS complex locus | -0.0447385 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | -0.0438323 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0437236 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0427771 |
| SLMAP | sarcolemma associated protein | -0.0425679 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0422535 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0418459 |
| FOXO3 | forkhead box O3 | -0.0413878 |
| SDC4 | syndecan 4 | -0.0411815 |
| ASPH | aspartate beta-hydroxylase | -0.0410381 |
| ITGB4 | integrin, beta 4 | -0.0409334 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0406701 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0404184 |
| NPSR1 | neuropeptide S receptor 1 | -0.0402535 |
| UBC | ubiquitin C | -0.0391447 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.038827 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0388019 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0381599 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0376012 |
| PGK1 | phosphoglycerate kinase 1 | -0.0368635 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.036841 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0364915 |
| HYCC2 | hyccin PI4KA lipid kinase complex subunit 2 | -0.0359287 |
| TMEM41B | transmembrane protein 41B | -0.0358826 |
| ANLN | anillin, actin binding protein | -0.0358714 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0355591 |
| JUP | junction plakoglobin | -0.0353223 |
| LDHA | lactate dehydrogenase A | -0.0349429 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0347428 |
| KRT8 | keratin 8, type II | -0.0345679 |
| OGA | O-GlcNAcase | -0.034013 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0336123 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0328894 |
| S100A11 | S100 calcium binding protein A11 | -0.0324582 |
| MYO6 | myosin VI | -0.0323905 |
| NDRG1 | N-myc downstream regulated 1 | -0.0323656 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0323177 |
| ZNF292 | zinc finger protein 292 | -0.032178 |
| LAMA4 | laminin, alpha 4 | -0.0321491 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0319337 |
| CD9 | CD9 molecule | -0.031345 |
| ARF4 | ADP-ribosylation factor 4 | -0.0311972 |
| DSG2 | desmoglein 2 | -0.0310337 |
| IER3 | immediate early response 3 | -0.0305685 |
| THOC2 | THO complex 2 | -0.0302754 |
| RPL8 | ribosomal protein L8 | -0.0301079 |
| PRSS3 | protease, serine, 3 | -0.0300926 |
| PFN1 | profilin 1 | -0.0300341 |
| RPS21 | ribosomal protein S21 | -0.0290646 |
