| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | RMC-6236 perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the RMC-6236_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.177987 |
| COL5A2 | collagen, type V, alpha 2 | 0.0989669 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0781418 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.07296 |
| ZNF608 | zinc finger protein 608 | 0.0698795 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0689971 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0582536 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0570186 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0534546 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0497376 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0489297 |
| JUN | jun proto-oncogene | 0.0473207 |
| DST | dystonin | 0.0465815 |
| B2M | beta-2-microglobulin | 0.0451963 |
| PCBP2 | poly(rC) binding protein 2 | 0.0449061 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0438053 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0410641 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0402242 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | 0.0393607 |
| RPS12 | ribosomal protein S12 | 0.038995 |
| JMJD1C | jumonji domain containing 1C | 0.037578 |
| PCNX4 | pecanex 4 | 0.0372164 |
| ENO1 | enolase 1, (alpha) | 0.0358394 |
| RHOA | ras homolog family member A | 0.0344864 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0340408 |
| TOX | thymocyte selection-associated high mobility group box | 0.0335961 |
| NBEAL1 | neurobeachin-like 1 | 0.0330677 |
| CADM2 | cell adhesion molecule 2 | 0.0321312 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0318038 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0316727 |
| MAP1B | microtubule-associated protein 1B | 0.0308174 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0297508 |
| RPS2 | ribosomal protein S2 | 0.0294615 |
| SON | SON DNA binding protein | 0.0293399 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0290128 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0284755 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0275534 |
| RPS3 | ribosomal protein S3 | 0.0275525 |
| BRD2 | bromodomain containing 2 | 0.0271101 |
| SIK2 | salt-inducible kinase 2 | 0.0268478 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0265661 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0264819 |
| MATR3 | matrin 3 | 0.0261651 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0256015 |
| BNC2 | basonuclin 2 | 0.0252886 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0249801 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0249698 |
| CEP112 | centrosomal protein 112kDa | 0.024853 |
| RPL12 | ribosomal protein L12 | 0.0243123 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0242724 |
| SMC3 | structural maintenance of chromosomes 3 | 0.023849 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0236861 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0233776 |
| RPS8 | ribosomal protein S8 | 0.0229454 |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta | 0.0226725 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0223172 |
| ADAR | adenosine deaminase, RNA-specific | 0.0223016 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.022259 |
| OGA | O-GlcNAcase | 0.0221992 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0221663 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0219619 |
| SYAP1 | synapse associated protein 1 | 0.021327 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.0212402 |
| TPI1 | triosephosphate isomerase 1 | 0.0212237 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0210233 |
| RACK1 | receptor for activated C kinase 1 | 0.0210154 |
| KLF6 | Kruppel-like factor 6 | 0.0209276 |
| ATF4 | activating transcription factor 4 | 0.0209072 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0206281 |
| H1-0 | H1.0 linker histone | 0.0206214 |
| CEP350 | centrosomal protein 350kDa | 0.0205613 |
| TPM3 | tropomyosin 3 | 0.0205015 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0204892 |
| NFIB | nuclear factor I/B | 0.0202191 |
| SCARB2 | scavenger receptor class B, member 2 | 0.0199796 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0199087 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0198843 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.019801 |
| RPS17 | ribosomal protein S17 | 0.0197454 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0196553 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.019416 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0192598 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.019189 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0191873 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0191365 |
| USP47 | ubiquitin specific peptidase 47 | 0.0190729 |
| MLIP | muscular LMNA-interacting protein | 0.018924 |
| GOLGB1 | golgin B1 | 0.0189022 |
| YBX1 | Y box binding protein 1 | 0.0188072 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0187138 |
| KIF5B | kinesin family member 5B | 0.0186281 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0186222 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0186074 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0182492 |
| CCDC88A | coiled-coil domain containing 88A | 0.0182043 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0182017 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0181369 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0181239 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.018046 |
| CALD1 | caldesmon 1 | 0.0180121 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.127933 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.125655 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.114364 |
| RAD51B | RAD51 paralog B | -0.111772 |
| NPAS3 | neuronal PAS domain protein 3 | -0.110442 |
| NEBL | nebulette | -0.0981273 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0945707 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0899228 |
| SMYD3 | SET and MYND domain containing 3 | -0.078416 |
| TENM3 | teneurin transmembrane protein 3 | -0.0740347 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0584959 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0579076 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0565433 |
| ATP11A | ATPase, class VI, type 11A | -0.0550035 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0536023 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0507466 |
| ACTG1 | actin gamma 1 | -0.0495488 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0453677 |
| FMNL2 | formin-like 2 | -0.0435957 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0430599 |
| PRICKLE1 | prickle homolog 1 (Drosophila) | -0.0429237 |
| DENND1A | DENN/MADD domain containing 1A | -0.0422346 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0405649 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0392818 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0392813 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0373413 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0368913 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0360514 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0358285 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.035449 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0335026 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0334833 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0333559 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.032612 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0316148 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.031144 |
| MDN1 | MDN1, midasin homolog (yeast) | -0.0303199 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0302405 |
| R3HDM1 | R3H domain containing 1 | -0.0294412 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0292564 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0287875 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0287689 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0287324 |
| AFG2A | AFG2 AAA ATPase homolog A | -0.0284887 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0283821 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | -0.0283675 |
| RPS21 | ribosomal protein S21 | -0.0279615 |
| SRPK1 | SRSF protein kinase 1 | -0.0279088 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.027684 |
| SRPK2 | SRSF protein kinase 2 | -0.027069 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0268835 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0267174 |
| NF1 | neurofibromin 1 | -0.0264669 |
| TXNRD1 | thioredoxin reductase 1 | -0.026447 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.026136 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0259572 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0258278 |
| HMGA1 | high mobility group AT-hook 1 | -0.0257219 |
| RPS24 | ribosomal protein S24 | -0.0250396 |
| EPN2 | epsin 2 | -0.0248871 |
| KIAA1958 | KIAA1958 | -0.0245276 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0240295 |
| RPL38 | ribosomal protein L38 | -0.0238901 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.0235087 |
| ZNF217 | zinc finger protein 217 | -0.0231872 |
| EGR1 | early growth response 1 | -0.0231201 |
| NXN | nucleoredoxin | -0.0231153 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0230645 |
| GSE1 | Gse1 coiled-coil protein | -0.0227741 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0226184 |
| TMEM41B | transmembrane protein 41B | -0.0225575 |
| ATRN | attractin | -0.0225402 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0225146 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.022368 |
| ABI2 | abl-interactor 2 | -0.022321 |
| TASOR2 | transcription activation suppressor family member 2 | -0.0223011 |
| TMEM123 | transmembrane protein 123 | -0.0222526 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0221134 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0218952 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | -0.0218335 |
| TPD52 | tumor protein D52 | -0.0218263 |
| XPO7 | exportin 7 | -0.0217895 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0216113 |
| RFX7 | regulatory factor X, 7 | -0.0215876 |
| TRAF3 | TNF receptor-associated factor 3 | -0.0212764 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.0212249 |
| RPL27A | ribosomal protein L27a | -0.0211868 |
| DIDO1 | death inducer-obliterator 1 | -0.0207726 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0207663 |
| EMP1 | epithelial membrane protein 1 | -0.0207561 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0207272 |
| TBC1D32 | TBC1 domain family, member 32 | -0.0206307 |
| MAP4 | microtubule-associated protein 4 | -0.020629 |
| PTK2 | protein tyrosine kinase 2 | -0.0206072 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0205636 |
| BLTP2 | bridge-like lipid transfer protein family member 2 | -0.0205456 |
| RPS11 | ribosomal protein S11 | -0.0205041 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | -0.0204401 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0202489 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0201727 |
