| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | RMC-6236 perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the RMC-6236_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.184076 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0865109 |
| CFB | complement factor B | 0.0748025 |
| B2M | beta-2-microglobulin | 0.0655622 |
| SMAD3 | SMAD family member 3 | 0.0635926 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0590876 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0536476 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0492664 |
| LCN2 | lipocalin 2 | 0.0458504 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0454138 |
| EFNA5 | ephrin-A5 | 0.0442375 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0434979 |
| TGM2 | transglutaminase 2 | 0.042998 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0427328 |
| SGMS2 | sphingomyelin synthase 2 | 0.0406647 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0393542 |
| FAM107B | family with sequence similarity 107, member B | 0.0382913 |
| CP | ceruloplasmin (ferroxidase) | 0.0373703 |
| PCBP2 | poly(rC) binding protein 2 | 0.0371591 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.036059 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0347538 |
| FGB | fibrinogen beta chain | 0.0335258 |
| DUOX2 | dual oxidase 2 | 0.032176 |
| KYNU | kynureninase | 0.031899 |
| APOL1 | apolipoprotein L, 1 | 0.0309185 |
| NTN4 | netrin 4 | 0.0308314 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0297361 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.029506 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0289774 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0284806 |
| SFTPA2 | surfactant protein A2 | 0.0282027 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0277772 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0277229 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0275171 |
| ARRDC3 | arrestin domain containing 3 | 0.0255241 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.0254714 |
| GBP4 | guanylate binding protein 4 | 0.0238722 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0231031 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0230363 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0228513 |
| NRG3 | neuregulin 3 | 0.022582 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0225472 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0222616 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0222241 |
| IL6 | interleukin 6 | 0.0216117 |
| SHROOM3 | shroom family member 3 | 0.0209216 |
| RAD51B | RAD51 paralog B | 0.0206181 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 0.0201252 |
| MYOF | myoferlin | 0.0198475 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.019579 |
| SGPP2 | sphingosine-1-phosphate phosphatase 2 | 0.0195283 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.0192628 |
| RPS2 | ribosomal protein S2 | 0.0192589 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0192455 |
| TXNIP | thioredoxin interacting protein | 0.0191493 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0190808 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0190215 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0187906 |
| VEGFA | vascular endothelial growth factor A | 0.0186453 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0181809 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0180012 |
| CIB1 | calcium and integrin binding 1 (calmyrin) | 0.0173044 |
| TSPAN15 | tetraspanin 15 | 0.0172854 |
| C3 | complement component 3 | 0.0172188 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0170905 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0164319 |
| MEIS1 | Meis homeobox 1 | 0.0163873 |
| CEP44 | centrosomal protein 44kDa | 0.0163358 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0161774 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0159128 |
| KRT17 | keratin 17, type I | 0.0158779 |
| SON | SON DNA binding protein | 0.0155137 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0153723 |
| KSR1 | kinase suppressor of ras 1 | 0.0151784 |
| MT1E | metallothionein 1E | 0.0149922 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0148367 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0148066 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0146848 |
| HOMER2 | homer scaffolding protein 2 | 0.0145641 |
| PROM1 | prominin 1 | 0.0145546 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0145449 |
| MT1G | metallothionein 1G | 0.0143886 |
| BARX2 | BARX homeobox 2 | 0.0142251 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0142172 |
| MYO1E | myosin IE | 0.0141313 |
| MLF1 | myeloid leukemia factor 1 | 0.0139633 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0139039 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0138992 |
| RPL3 | ribosomal protein L3 | 0.0138239 |
| ATF3 | activating transcription factor 3 | 0.0137047 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.0134529 |
| FHL2 | four and a half LIM domains 2 | 0.0134515 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0134148 |
| PLEC | plectin | 0.0133219 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0132503 |
| MX2 | MX dynamin-like GTPase 2 | 0.0130147 |
| IFI44L | interferon-induced protein 44-like | 0.0128761 |
| PCDH1 | protocadherin 1 | 0.0128253 |
| TMC5 | transmembrane channel-like 5 | 0.012815 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0127613 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.244552 |
| MMP7 | matrix metallopeptidase 7 | -0.192376 |
| TMSB10 | thymosin beta 10 | -0.139552 |
| PTMA | prothymosin, alpha | -0.114822 |
| ACTG1 | actin gamma 1 | -0.108528 |
| S100A6 | S100 calcium binding protein A6 | -0.0979227 |
| NDRG1 | N-myc downstream regulated 1 | -0.0865311 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0855976 |
| ANXA2 | annexin A2 | -0.0850188 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0821941 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0789596 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0767296 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0732881 |
| FTL | ferritin, light polypeptide | -0.0717835 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0700703 |
| ASPH | aspartate beta-hydroxylase | -0.0692935 |
| DTNA | dystrobrevin, alpha | -0.0683663 |
| POTEF | POTE ankyrin domain family, member F | -0.0680265 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0657312 |
| S100A10 | S100 calcium binding protein A10 | -0.0657081 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0643025 |
| LAMB3 | laminin, beta 3 | -0.0640929 |
| KRT19 | keratin 19, type I | -0.061259 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0606377 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0600222 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0595213 |
| DSG2 | desmoglein 2 | -0.0591833 |
| GNAS | GNAS complex locus | -0.0589451 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0576059 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0572557 |
| PKM | pyruvate kinase, muscle | -0.0572142 |
| DST | dystonin | -0.055768 |
| FLNB | filamin B, beta | -0.0554417 |
| HMGA1 | high mobility group AT-hook 1 | -0.0552621 |
| VIM | vimentin | -0.0543316 |
| RTN4 | reticulon 4 | -0.0541358 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0539766 |
| PGK1 | phosphoglycerate kinase 1 | -0.0538377 |
| UBC | ubiquitin C | -0.0536835 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0520665 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0514327 |
| HLA-B | major histocompatibility complex, class I, B | -0.0511955 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0499165 |
| SPAG9 | sperm associated antigen 9 | -0.0485442 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0484459 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0481828 |
| LMO7 | LIM domain 7 | -0.0479257 |
| MAP1B | microtubule-associated protein 1B | -0.04547 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0452774 |
| RPS29 | ribosomal protein S29 | -0.0451458 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0443131 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0434887 |
| PARD3 | par-3 family cell polarity regulator | -0.0434593 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0432045 |
| OGA | O-GlcNAcase | -0.0426651 |
| ENO1 | enolase 1, (alpha) | -0.0426552 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0425943 |
| PLAT | plasminogen activator, tissue | -0.0425689 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0422356 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0422289 |
| RPL19 | ribosomal protein L19 | -0.041146 |
| PLAU | plasminogen activator, urokinase | -0.0411021 |
| ACTN4 | actinin, alpha 4 | -0.0409395 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0409136 |
| TPM4 | tropomyosin 4 | -0.0400189 |
| SYNRG | synergin, gamma | -0.0395546 |
| LASP1 | LIM and SH3 protein 1 | -0.0395527 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0395365 |
| RPS6 | ribosomal protein S6 | -0.0392838 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0389202 |
| MCU | mitochondrial calcium uniporter | -0.0389197 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0388995 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0386764 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0386558 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0382868 |
| IER3 | immediate early response 3 | -0.0380942 |
| JMJD1C | jumonji domain containing 1C | -0.0375512 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0375395 |
| NCKAP5 | NCK-associated protein 5 | -0.0373988 |
| VCL | vinculin | -0.0372812 |
| LAMC2 | laminin, gamma 2 | -0.0371595 |
| RPLP1 | ribosomal protein, large, P1 | -0.0370597 |
| ITGA6 | integrin, alpha 6 | -0.0370449 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0369111 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0368663 |
| RPL34 | ribosomal protein L34 | -0.0366856 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.036351 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0363107 |
| AHNAK | AHNAK nucleoprotein | -0.0361027 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0357495 |
| RPS21 | ribosomal protein S21 | -0.0352042 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0347858 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0345978 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0345317 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0342773 |
| CDK6 | cyclin-dependent kinase 6 | -0.0333768 |
| PRKCA | protein kinase C, alpha | -0.0333586 |
| ERBIN | erbb2 interacting protein | -0.0333204 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0332237 |
| MEF2A | myocyte enhancer factor 2A | -0.0331843 |
