| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | RMC-6236 perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the RMC-6236_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.162408 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.097582 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.084119 |
| VIM | vimentin | 0.0830661 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0697356 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0695342 |
| MAP1B | microtubule-associated protein 1B | 0.0608935 |
| B2M | beta-2-microglobulin | 0.0601696 |
| PCBP2 | poly(rC) binding protein 2 | 0.0573993 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0529782 |
| RPL23 | ribosomal protein L23 | 0.052419 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0499662 |
| RPS6 | ribosomal protein S6 | 0.0441709 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.043452 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.04328 |
| RUNX1 | runt-related transcription factor 1 | 0.0424181 |
| RPS12 | ribosomal protein S12 | 0.0400712 |
| CTSB | cathepsin B | 0.039853 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0378984 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.036137 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0351269 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.034854 |
| FAM107B | family with sequence similarity 107, member B | 0.0347162 |
| PKM | pyruvate kinase, muscle | 0.0338802 |
| CALD1 | caldesmon 1 | 0.0335901 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0324223 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0321837 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0314938 |
| RPL12 | ribosomal protein L12 | 0.0310247 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0308524 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0305866 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0304021 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0302909 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0288215 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0277515 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0276302 |
| RPS3 | ribosomal protein S3 | 0.0271897 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0263973 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0262821 |
| PTMA | prothymosin, alpha | 0.0257646 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0256591 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0253899 |
| RPS14 | ribosomal protein S14 | 0.0252458 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0252322 |
| VEGFA | vascular endothelial growth factor A | 0.0251484 |
| RPL36 | ribosomal protein L36 | 0.0247254 |
| RPS2 | ribosomal protein S2 | 0.024705 |
| MMP2 | matrix metallopeptidase 2 | 0.0246663 |
| RPL3 | ribosomal protein L3 | 0.0242055 |
| RACK1 | receptor for activated C kinase 1 | 0.024159 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.023787 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.023661 |
| RPLP1 | ribosomal protein, large, P1 | 0.0235473 |
| ADAR | adenosine deaminase, RNA-specific | 0.0233144 |
| SET | SET nuclear proto-oncogene | 0.0231362 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | 0.0230945 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.0230856 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0229436 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0227496 |
| ZFP36 | ZFP36 ring finger protein | 0.0226382 |
| RPL19 | ribosomal protein L19 | 0.0225703 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0221714 |
| SPOP | speckle-type POZ protein | 0.0220794 |
| ENO1 | enolase 1, (alpha) | 0.0217489 |
| RPL26 | ribosomal protein L26 | 0.0215991 |
| RPS27 | ribosomal protein S27 | 0.0214713 |
| RPL27 | ribosomal protein L27 | 0.0212216 |
| RPS19 | ribosomal protein S19 | 0.0211558 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0210602 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0209863 |
| OPTN | optineurin | 0.0209676 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0207843 |
| ATF4 | activating transcription factor 4 | 0.0207544 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0203306 |
| SCG2 | secretogranin II | 0.0199899 |
| STC1 | stanniocalcin 1 | 0.0199361 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.0197335 |
| CBX3 | chromobox homolog 3 | 0.019665 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0195648 |
| RPL18 | ribosomal protein L18 | 0.0195237 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.0195123 |
| SFTPA2 | surfactant protein A2 | 0.0192117 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0189967 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0189502 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0189366 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0187928 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0187555 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0186003 |
| RPS27A | ribosomal protein S27a | 0.0184408 |
| RSF1 | remodeling and spacing factor 1 | 0.0183691 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0181575 |
| NBR1 | neighbor of BRCA1 gene 1 | 0.0178947 |
| ARRDC3 | arrestin domain containing 3 | 0.0177763 |
| MX1 | MX dynamin-like GTPase 1 | 0.0177726 |
| PCM1 | pericentriolar material 1 | 0.0177401 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0176253 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.01762 |
| DHX40 | DEAH (Asp-Glu-Ala-His) box polypeptide 40 | 0.0175819 |
| DGKH | diacylglycerol kinase, eta | 0.017542 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0175036 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | -0.166074 |
| LSAMP | limbic system-associated membrane protein | -0.153893 |
| IGF2 | insulin-like growth factor 2 | -0.107053 |
| VCL | vinculin | -0.103423 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0765098 |
| NREP | neuronal regeneration related protein | -0.0722492 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0660157 |
| MSI2 | musashi RNA-binding protein 2 | -0.057286 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0564782 |
| MEIS2 | Meis homeobox 2 | -0.0550568 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0517408 |
| TRIB2 | tribbles pseudokinase 2 | -0.0481926 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0459214 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0456451 |
| MAPK10 | mitogen-activated protein kinase 10 | -0.0426644 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0416867 |
| CUX1 | cut-like homeobox 1 | -0.0416744 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.0416725 |
| EGR1 | early growth response 1 | -0.039986 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0397674 |
| COL3A1 | collagen, type III, alpha 1 | -0.0390062 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0379014 |
| FMN1 | formin 1 | -0.0377925 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0373275 |
| CCDC47 | coiled-coil domain containing 47 | -0.0371021 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0370634 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0368734 |
| LRRC7 | leucine rich repeat containing 7 | -0.0367473 |
| ENAH | enabled homolog (Drosophila) | -0.0366077 |
| PRKCA | protein kinase C, alpha | -0.0359985 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0356873 |
| RAD51B | RAD51 paralog B | -0.0355345 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0354833 |
| TPM1 | tropomyosin 1 (alpha) | -0.0351917 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0349713 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0339908 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0331325 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0324052 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0315068 |
| AOPEP | aminopeptidase O (putative) | -0.0313343 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0311502 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0310859 |
| PLAT | plasminogen activator, tissue | -0.0310815 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0306946 |
| SPAG9 | sperm associated antigen 9 | -0.0300794 |
| STK38L | serine/threonine kinase 38 like | -0.0299484 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0298812 |
| AK1 | adenylate kinase 1 | -0.0296356 |
| KCNIP4 | Kv channel interacting protein 4 | -0.029506 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0293367 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0288357 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.0286471 |
| RALYL | RALY RNA binding protein-like | -0.0285138 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0284568 |
| RNF150 | ring finger protein 150 | -0.0283433 |
| CNTN4 | contactin 4 | -0.028161 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0279833 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0278661 |
| VMP1 | vacuole membrane protein 1 | -0.0272815 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.027143 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0270972 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0269885 |
| RPS24 | ribosomal protein S24 | -0.0269008 |
| RBM39 | RNA binding motif protein 39 | -0.0265715 |
| PTK2 | protein tyrosine kinase 2 | -0.0265656 |
| THBS1 | thrombospondin 1 | -0.0263985 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0263793 |
| ZNF292 | zinc finger protein 292 | -0.0262669 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0262474 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0261148 |
| SPAG16 | sperm associated antigen 16 | -0.0259821 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0259163 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0258948 |
| GSE1 | Gse1 coiled-coil protein | -0.025853 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0256444 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | -0.0255974 |
| PCDH15 | protocadherin-related 15 | -0.0254193 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0252215 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0251408 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0247564 |
| CADM2 | cell adhesion molecule 2 | -0.0247044 |
| RHEB | Ras homolog enriched in brain | -0.0245459 |
| QKI | QKI, KH domain containing, RNA binding | -0.0244868 |
| TLK2 | tousled-like kinase 2 | -0.0244411 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0244179 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0242589 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0241738 |
| HIP1 | huntingtin interacting protein 1 | -0.0241096 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0240764 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.024046 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0240104 |
| FOXK2 | forkhead box K2 | -0.0239923 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0238582 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0236681 |
| TFRC | transferrin receptor | -0.0235196 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.023517 |
| VAV2 | vav 2 guanine nucleotide exchange factor | -0.0233802 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0232838 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0230516 |
| RPL38 | ribosomal protein L38 | -0.0229947 |
