| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | RMC-6236 perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the RMC-6236_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.215435 |
| B2M | beta-2-microglobulin | 0.13218 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.122158 |
| DSPP | dentin sialophosphoprotein | 0.0931137 |
| LMO7 | LIM domain 7 | 0.0911264 |
| FTL | ferritin, light polypeptide | 0.0893165 |
| TMC5 | transmembrane channel-like 5 | 0.0849965 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.078893 |
| EZR | ezrin | 0.0755888 |
| RNF213 | ring finger protein 213 | 0.0755738 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0667121 |
| LCN2 | lipocalin 2 | 0.0629154 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0552353 |
| MYOF | myoferlin | 0.054583 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | 0.0504212 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0481864 |
| CLDN4 | claudin 4 | 0.0473177 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0446932 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.04403 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0437789 |
| TXNIP | thioredoxin interacting protein | 0.0430772 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0429337 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0429026 |
| GDA | guanine deaminase | 0.0422569 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | 0.0393699 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0390251 |
| DSTN | destrin (actin depolymerizing factor) | 0.0390009 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0389984 |
| TMEM45B | transmembrane protein 45B | 0.0383235 |
| ATF5 | activating transcription factor 5 | 0.0369384 |
| TMSB4X | thymosin beta 4, X-linked | 0.0364297 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0340613 |
| APOL1 | apolipoprotein L, 1 | 0.0319749 |
| KLF6 | Kruppel-like factor 6 | 0.0315076 |
| ATF4 | activating transcription factor 4 | 0.0312109 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0303542 |
| KRT17 | keratin 17, type I | 0.0302279 |
| SFTPA2 | surfactant protein A2 | 0.0300651 |
| RPS12 | ribosomal protein S12 | 0.0300605 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0291202 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.028522 |
| RPS3 | ribosomal protein S3 | 0.0276515 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0276358 |
| SP100 | SP100 nuclear antigen | 0.0274695 |
| VEGFA | vascular endothelial growth factor A | 0.026185 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0257629 |
| TJP1 | tight junction protein 1 | 0.0247702 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0243252 |
| RUNX1 | runt-related transcription factor 1 | 0.0241445 |
| MUC13 | mucin 13, cell surface associated | 0.0233573 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.023213 |
| PCBP2 | poly(rC) binding protein 2 | 0.0231713 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | 0.02308 |
| RPL35A | ribosomal protein L35a | 0.0230679 |
| RPS19 | ribosomal protein S19 | 0.0230627 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0226418 |
| JUN | jun proto-oncogene | 0.0223798 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0220543 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0216139 |
| MX2 | MX dynamin-like GTPase 2 | 0.0215184 |
| HDAC9 | histone deacetylase 9 | 0.0213236 |
| CTSB | cathepsin B | 0.0210756 |
| KIF16B | kinesin family member 16B | 0.0209028 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0207884 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.020759 |
| SET | SET nuclear proto-oncogene | 0.0204854 |
| CLMN | calmin (calponin-like, transmembrane) | 0.0197823 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0195554 |
| RPS2 | ribosomal protein S2 | 0.0193225 |
| MGAM2 | maltase-glucoamylase 2 (putative) | 0.0193112 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0192406 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0192356 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0188875 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0188815 |
| HLA-E | major histocompatibility complex, class I, E | 0.0186606 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0185603 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0185097 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0184533 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0181281 |
| RPS8 | ribosomal protein S8 | 0.0178876 |
| RPS6 | ribosomal protein S6 | 0.01758 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | 0.017562 |
| MYZAP | myocardial zonula adherens protein | 0.017545 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0174537 |
| MYADM | myeloid-associated differentiation marker | 0.0174427 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0170517 |
| RHOB | ras homolog family member B | 0.016878 |
| SLFN5 | schlafen family member 5 | 0.0166712 |
| RPS27 | ribosomal protein S27 | 0.0166135 |
| SCARB2 | scavenger receptor class B, member 2 | 0.016598 |
| ATF3 | activating transcription factor 3 | 0.016515 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0164458 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0164214 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0162288 |
| TMF1 | TATA element modulatory factor 1 | 0.0161602 |
| ATP9A | ATPase, class II, type 9A | 0.0161491 |
| MX1 | MX dynamin-like GTPase 1 | 0.0161301 |
| DST | dystonin | 0.0160712 |
| PCDH1 | protocadherin 1 | 0.0158857 |
| TCP11L2 | t-complex 11, testis-specific-like 2 | 0.0158203 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GMDS | GDP-mannose 4,6-dehydratase | -0.249826 |
| NPSR1 | neuropeptide S receptor 1 | -0.185747 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.150621 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.146823 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.130719 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.107022 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.106662 |
| EMP1 | epithelial membrane protein 1 | -0.106577 |
| FLNB | filamin B, beta | -0.0966247 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0916745 |
| ANXA2 | annexin A2 | -0.0893055 |
| KRT8 | keratin 8, type II | -0.0863123 |
| BCL2L1 | BCL2-like 1 | -0.0851985 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.083086 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.081357 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0706754 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0691728 |
| EHBP1 | EH domain binding protein 1 | -0.069005 |
| TNIK | TRAF2 and NCK interacting kinase | -0.0682158 |
| ACTN4 | actinin, alpha 4 | -0.0653647 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0598336 |
| AGR2 | anterior gradient 2 | -0.0591315 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0582079 |
| ASPH | aspartate beta-hydroxylase | -0.0561593 |
| PRKCA | protein kinase C, alpha | -0.0557602 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | -0.0521241 |
| KRT18 | keratin 18, type I | -0.0516313 |
| ANLN | anillin, actin binding protein | -0.0507748 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0500825 |
| FAT1 | FAT atypical cadherin 1 | -0.0500705 |
| S100A10 | S100 calcium binding protein A10 | -0.0477124 |
| S100A6 | S100 calcium binding protein A6 | -0.0475253 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.047408 |
| TMEM123 | transmembrane protein 123 | -0.0446884 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0446379 |
| CAPN8 | calpain 8 | -0.044409 |
| ECT2 | epithelial cell transforming 2 | -0.0437408 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0436681 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0428583 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0427701 |
| WWC1 | WW and C2 domain containing 1 | -0.0420483 |
| ITGA6 | integrin, alpha 6 | -0.0412328 |
| VMP1 | vacuole membrane protein 1 | -0.0407149 |
| TMSB10 | thymosin beta 10 | -0.0405044 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0393949 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0391487 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0386796 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0380331 |
| RBM39 | RNA binding motif protein 39 | -0.037898 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0376288 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.037593 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0375923 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0371719 |
| YAP1 | Yes-associated protein 1 | -0.0367365 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0363384 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0360636 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0358018 |
| ACACA | acetyl-CoA carboxylase alpha | -0.03564 |
| GNAS | GNAS complex locus | -0.0355392 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0353017 |
| ITGB4 | integrin, beta 4 | -0.0352342 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.034889 |
| KLHL29 | kelch-like family member 29 | -0.0342465 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0340133 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0339649 |
| FBXO11 | F-box protein 11 | -0.0339422 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0336568 |
| MED13 | mediator complex subunit 13 | -0.0335551 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0332614 |
| NF1 | neurofibromin 1 | -0.0332097 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0327676 |
| MECOM | MDS1 and EVI1 complex locus | -0.0324517 |
| TFRC | transferrin receptor | -0.0323203 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0321174 |
| SULF2 | sulfatase 2 | -0.0309911 |
| H1-0 | H1.0 linker histone | -0.0309145 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | -0.0308323 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0308012 |
| ATXN1 | ataxin 1 | -0.0301647 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0299332 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | -0.0297585 |
| CLTC | clathrin, heavy chain (Hc) | -0.0294797 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0292093 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0292038 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0289512 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0288869 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0284481 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0284038 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0282296 |
| VCL | vinculin | -0.02821 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.0279595 |
| RPS24 | ribosomal protein S24 | -0.0278847 |
| CTBP2 | C-terminal binding protein 2 | -0.0278618 |
| DEK | DEK proto-oncogene | -0.0277961 |
| EGR1 | early growth response 1 | -0.0275653 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0275613 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0275478 |
| GLG1 | golgi glycoprotein 1 | -0.0274147 |
| NHSL1 | NHS-like 1 | -0.0272989 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0268425 |
