| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | RMC-6236 perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the RMC-6236_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.164749 |
| EXT1 | exostosin glycosyltransferase 1 | 0.121725 |
| CD44 | CD44 molecule (Indian blood group) | 0.0919114 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0900788 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0853328 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0824349 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0771132 |
| RPS2 | ribosomal protein S2 | 0.0752207 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0698598 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0695338 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0660973 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0638603 |
| RPL23 | ribosomal protein L23 | 0.0624883 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0618458 |
| PCBP2 | poly(rC) binding protein 2 | 0.0590801 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0585526 |
| RPS12 | ribosomal protein S12 | 0.0558179 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0530625 |
| FTL | ferritin, light polypeptide | 0.049948 |
| RPL12 | ribosomal protein L12 | 0.049521 |
| HDAC9 | histone deacetylase 9 | 0.0484897 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0479451 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.047302 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0466315 |
| HMGA2 | high mobility group AT-hook 2 | 0.0459506 |
| RPS3 | ribosomal protein S3 | 0.0434831 |
| RACK1 | receptor for activated C kinase 1 | 0.0434554 |
| FLNA | filamin A, alpha | 0.041515 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0401223 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0394735 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0364403 |
| RPL37A | ribosomal protein L37a | 0.0363757 |
| RPS8 | ribosomal protein S8 | 0.0356242 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0355959 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0339529 |
| RPS18 | ribosomal protein S18 | 0.0333606 |
| NAV3 | neuron navigator 3 | 0.0333415 |
| RPS17 | ribosomal protein S17 | 0.0333016 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0330946 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0325338 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0318645 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0318124 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0317763 |
| MSN | moesin | 0.0313405 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0311997 |
| RPL27 | ribosomal protein L27 | 0.0304497 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0301631 |
| RPS4X | ribosomal protein S4, X-linked | 0.0299507 |
| TLN1 | talin 1 | 0.0296881 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0294829 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.029458 |
| RPL3 | ribosomal protein L3 | 0.0292178 |
| RPL7 | ribosomal protein L7 | 0.02906 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0283539 |
| ASPH | aspartate beta-hydroxylase | 0.0282341 |
| SON | SON DNA binding protein | 0.0278928 |
| TXNIP | thioredoxin interacting protein | 0.0278383 |
| ZNF638 | zinc finger protein 638 | 0.0270213 |
| YBX1 | Y box binding protein 1 | 0.0267363 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0262009 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0261499 |
| GPHN | gephyrin | 0.0259633 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.025833 |
| BRD2 | bromodomain containing 2 | 0.0250865 |
| TPM3 | tropomyosin 3 | 0.0249224 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0249071 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0247347 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0244167 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0241011 |
| RPL26 | ribosomal protein L26 | 0.023197 |
| FRMD6 | FERM domain containing 6 | 0.022931 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0228584 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0228056 |
| SET | SET nuclear proto-oncogene | 0.0227931 |
| KLHL29 | kelch-like family member 29 | 0.0226128 |
| RPL5 | ribosomal protein L5 | 0.0225391 |
| IRS2 | insulin receptor substrate 2 | 0.022477 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0222323 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0219933 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0217285 |
| IPO7 | importin 7 | 0.021415 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0212682 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0210284 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0209037 |
| RPS6 | ribosomal protein S6 | 0.0208206 |
| MT2A | metallothionein 2A | 0.0208135 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0203936 |
| OR51B5 | olfactory receptor, family 51, subfamily B, member 5 | 0.0202348 |
| RPS19 | ribosomal protein S19 | 0.0201578 |
| ITGA6 | integrin, alpha 6 | 0.0200855 |
| EFNB2 | ephrin-B2 | 0.0199559 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0198237 |
| RPLP1 | ribosomal protein, large, P1 | 0.0193146 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0192955 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0192708 |
| RPS7 | ribosomal protein S7 | 0.0192341 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | 0.0190318 |
| ATF4 | activating transcription factor 4 | 0.0186583 |
| EPG5 | ectopic P-granules autophagy protein 5 homolog (C. elegans) | 0.0185595 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0185212 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MMP12 | matrix metallopeptidase 12 | -0.266121 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.13837 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.130754 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.107455 |
| LSAMP | limbic system-associated membrane protein | -0.105598 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.104708 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0971938 |
| DST | dystonin | -0.0918552 |
| TMSB10 | thymosin beta 10 | -0.0830862 |
| CDH13 | cadherin 13 | -0.0776741 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0765063 |
| VIM | vimentin | -0.0744309 |
| FN1 | fibronectin 1 | -0.0736485 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0685861 |
| GPC6 | glypican 6 | -0.0684948 |
| PTCHD4 | patched domain containing 4 | -0.0632951 |
| ANXA2 | annexin A2 | -0.063147 |
| PTK2 | protein tyrosine kinase 2 | -0.0598061 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0592163 |
| CD109 | CD109 molecule | -0.0579194 |
| SBF2 | SET binding factor 2 | -0.0562841 |
| GNAS | GNAS complex locus | -0.0552584 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0483782 |
| TPM4 | tropomyosin 4 | -0.048051 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.047573 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0471942 |
| ENKUR | enkurin, TRPC channel interacting protein | -0.0463793 |
| CFAP251 | cilia and flagella associated protein 251 | -0.0457287 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.0443409 |
| DTNA | dystrobrevin, alpha | -0.0439185 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0437086 |
| BNC2 | basonuclin 2 | -0.0432847 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0426818 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0417147 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0410444 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0405924 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0402543 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0392954 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0390862 |
| PTMA | prothymosin, alpha | -0.0386693 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0380214 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0378835 |
| VCL | vinculin | -0.0376671 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0368646 |
| ERBIN | erbb2 interacting protein | -0.0368071 |
| DNER | delta/notch-like EGF repeat containing | -0.036233 |
| TENM2 | teneurin transmembrane protein 2 | -0.0360293 |
| MAP3K7CL | MAP3K7 C-terminal like | -0.0359885 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0358343 |
| KIAA1217 | KIAA1217 | -0.0354461 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0354441 |
| ZNF804A | zinc finger protein 804A | -0.0354424 |
| NDRG1 | N-myc downstream regulated 1 | -0.0352919 |
| NTM | neurotrimin | -0.0350097 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0348709 |
| HAS2 | hyaluronan synthase 2 | -0.0341257 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0339153 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0332721 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0331583 |
| MAP4 | microtubule-associated protein 4 | -0.0321959 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0317803 |
| EFNA5 | ephrin-A5 | -0.0315169 |
| VEPH1 | ventricular zone expressed PH domain-containing 1 | -0.0310931 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0309071 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0308256 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0307769 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0307059 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0303653 |
| TMEM263 | transmembrane protein 263 | -0.030274 |
| WDR45B | WD repeat domain 45B | -0.0299822 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0296712 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0295593 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0291884 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0291157 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0288734 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0288194 |
| CDK17 | cyclin-dependent kinase 17 | -0.0286914 |
| WWC1 | WW and C2 domain containing 1 | -0.0285797 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0284248 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0278442 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0277275 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0275859 |
| CUX1 | cut-like homeobox 1 | -0.0274628 |
| SETD5 | SET domain containing 5 | -0.0272724 |
| SPAG9 | sperm associated antigen 9 | -0.027016 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0266883 |
| RIC1 | RAB6A GEF complex partner 1 | -0.0265922 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0264186 |
| VCAN | versican | -0.0262082 |
| ZNF292 | zinc finger protein 292 | -0.0260994 |
| NF1 | neurofibromin 1 | -0.0259126 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0258676 |
| WASF2 | WAS protein family, member 2 | -0.0257752 |
| DIAPH2 | diaphanous-related formin 2 | -0.0257559 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0257311 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0256729 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0253669 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0253576 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0253477 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0253089 |
