| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | RMC-6236 perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the RMC-6236_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.150977 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0510248 |
| PCBP2 | poly(rC) binding protein 2 | 0.0354599 |
| FAM13A | family with sequence similarity 13, member A | 0.033894 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0332079 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0331091 |
| ARRDC3 | arrestin domain containing 3 | 0.0327951 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0301926 |
| IRS2 | insulin receptor substrate 2 | 0.025828 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0242967 |
| SLTM | SAFB-like, transcription modulator | 0.0238691 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0234883 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0217688 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0216612 |
| TBC1D22A | TBC1 domain family, member 22A | 0.020483 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0190783 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0177735 |
| RPS3 | ribosomal protein S3 | 0.0174057 |
| ZNF638 | zinc finger protein 638 | 0.0154395 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0153676 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0149514 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0145655 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0144305 |
| RPS2 | ribosomal protein S2 | 0.0143816 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0143309 |
| SMAD3 | SMAD family member 3 | 0.0138852 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0138215 |
| RAD51B | RAD51 paralog B | 0.0133433 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.013173 |
| RPL3 | ribosomal protein L3 | 0.0125591 |
| RUNX1 | runt-related transcription factor 1 | 0.012398 |
| YBX3 | Y box binding protein 3 | 0.0123295 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0120098 |
| RPS12 | ribosomal protein S12 | 0.0110364 |
| MLF1 | myeloid leukemia factor 1 | 0.01091 |
| RPS3A | ribosomal protein S3A | 0.010455 |
| TBC1D15 | TBC1 domain family, member 15 | 0.00991369 |
| FNIP1 | folliculin interacting protein 1 | 0.00972245 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.00971051 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.00965872 |
| RPS7 | ribosomal protein S7 | 0.00962922 |
| KIAA1328 | KIAA1328 | 0.00956141 |
| SON | SON DNA binding protein | 0.00953793 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | 0.00951225 |
| BMP6 | bone morphogenetic protein 6 | 0.00940397 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.00922441 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0091257 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.00900816 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.00894718 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.00885007 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.00870047 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.00820668 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.00804816 |
| HSPA8 | heat shock 70kDa protein 8 | 0.00798321 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.00794118 |
| NGLY1 | N-glycanase 1 | 0.00788999 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.00772327 |
| HBP1 | HMG-box transcription factor 1 | 0.00765986 |
| YTHDC1 | YTH domain containing 1 | 0.00764039 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.00758128 |
| DHFR | dihydrofolate reductase | 0.00755999 |
| CSNK1E | casein kinase 1, epsilon | 0.0073495 |
| TTLL10 | tubulin tyrosine ligase-like family member 10 | 0.00733302 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.00732992 |
| CIB1 | calcium and integrin binding 1 (calmyrin) | 0.00725111 |
| NIPA1 | non imprinted in Prader-Willi/Angelman syndrome 1 | 0.00723207 |
| ATP13A3 | ATPase type 13A3 | 0.00721935 |
| ZNF292 | zinc finger protein 292 | 0.00705632 |
| CABLES1 | Cdk5 and Abl enzyme substrate 1 | 0.00695237 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.00693093 |
| ARGLU1 | arginine and glutamate rich 1 | 0.00682809 |
| IGSF9B | immunoglobulin superfamily, member 9B | 0.00670514 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.00660834 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0066018 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.006531 |
| CUL4A | cullin 4A | 0.00649993 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.00645815 |
| PER2 | period circadian clock 2 | 0.00644954 |
| MREG | melanoregulin | 0.00632869 |
| KYNU | kynureninase | 0.00625602 |
| BSDC1 | BSD domain containing 1 | 0.0061932 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.00615324 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.00614709 |
| ZFP36 | ZFP36 ring finger protein | 0.00603078 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.00589735 |
| GPC5 | glypican 5 | 0.00587092 |
| ADAR | adenosine deaminase, RNA-specific | 0.00579993 |
| HPS5 | Hermansky-Pudlak syndrome 5 | 0.0057518 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.00568058 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 | 0.00567628 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0056655 |
| B2M | beta-2-microglobulin | 0.00560426 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.00559515 |
| TMEM45B | transmembrane protein 45B | 0.00557188 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 0.00555915 |
| CHMP1B | charged multivesicular body protein 1B | 0.00555225 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.00553705 |
| H1-10 | H1.10 linker histone | 0.00553549 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.00549043 |
| VPS41 | vacuolar protein sorting 41 homolog (S. cerevisiae) | 0.00548852 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.312964 |
| ASPH | aspartate beta-hydroxylase | -0.193574 |
| TMSB10 | thymosin beta 10 | -0.148362 |
| TXNRD1 | thioredoxin reductase 1 | -0.143599 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.120966 |
| ACTG1 | actin gamma 1 | -0.119566 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.11121 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.109076 |
| LAMC2 | laminin, gamma 2 | -0.108475 |
| LMO7 | LIM domain 7 | -0.107005 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.10556 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0972832 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0913539 |
| S100A10 | S100 calcium binding protein A10 | -0.0889826 |
| PKM | pyruvate kinase, muscle | -0.0838088 |
| ANXA2 | annexin A2 | -0.0768826 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0741017 |
| KRT18 | keratin 18, type I | -0.0654999 |
| SCEL | sciellin | -0.065145 |
| PTMA | prothymosin, alpha | -0.0647266 |
| LDHA | lactate dehydrogenase A | -0.0640154 |
| PDLIM5 | PDZ and LIM domain 5 | -0.061837 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0616414 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.059875 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0595455 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0564689 |
| AHNAK | AHNAK nucleoprotein | -0.0553625 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0527074 |
| EGR1 | early growth response 1 | -0.0516366 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0508058 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0501673 |
| KRT7 | keratin 7, type II | -0.048421 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0476106 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0470905 |
| VCL | vinculin | -0.0465796 |
| RNF213 | ring finger protein 213 | -0.0461681 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0458944 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0450454 |
| TPM4 | tropomyosin 4 | -0.0446285 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0441723 |
| HDLBP | high density lipoprotein binding protein | -0.0432866 |
| CUX1 | cut-like homeobox 1 | -0.0423919 |
| USP53 | ubiquitin specific peptidase 53 | -0.0422913 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0418689 |
| TES | testin LIM domain protein | -0.0417637 |
| RAB10 | RAB10, member RAS oncogene family | -0.0411255 |
| KRT8 | keratin 8, type II | -0.0408402 |
| ENO1 | enolase 1, (alpha) | -0.0404525 |
| CCND1 | cyclin D1 | -0.0400862 |
| OSMR | oncostatin M receptor | -0.0399527 |
| MYOF | myoferlin | -0.0395802 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0389617 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0387777 |
| CST3 | cystatin C | -0.0384633 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0379544 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0376715 |
| GNAS | GNAS complex locus | -0.0375489 |
| AGR2 | anterior gradient 2 | -0.03752 |
| DSG2 | desmoglein 2 | -0.0373345 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0369255 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.036669 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0363941 |
| EZR | ezrin | -0.0349714 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0345044 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0343464 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0333481 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.033084 |
| PGK1 | phosphoglycerate kinase 1 | -0.0328605 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0324011 |
| IER3 | immediate early response 3 | -0.0323047 |
| IGF1R | insulin-like growth factor 1 receptor | -0.032081 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0319953 |
| H1-0 | H1.0 linker histone | -0.0317866 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.031612 |
| FBXO11 | F-box protein 11 | -0.0315537 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0311759 |
| RPS24 | ribosomal protein S24 | -0.0310078 |
| TJP1 | tight junction protein 1 | -0.0308578 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0307859 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0306943 |
| MCU | mitochondrial calcium uniporter | -0.0306098 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0305969 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0305064 |
| EHBP1 | EH domain binding protein 1 | -0.0303053 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.030147 |
| SEC61G | Sec61 gamma subunit | -0.0298919 |
| KPNB1 | karyopherin (importin) beta 1 | -0.029854 |
| PRKCA | protein kinase C, alpha | -0.0297881 |
| DSPP | dentin sialophosphoprotein | -0.0295038 |
| NABP1 | nucleic acid binding protein 1 | -0.0292797 |
| RPS25 | ribosomal protein S25 | -0.0291274 |
| GRAMD1B | GRAM domain containing 1B | -0.0290724 |
| FLNB | filamin B, beta | -0.0289622 |
| CDCP1 | CUB domain containing protein 1 | -0.028591 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0285801 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0282745 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0282513 |
| PTK2 | protein tyrosine kinase 2 | -0.0282027 |
| LAMA4 | laminin, alpha 4 | -0.0278878 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0273948 |
