| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | RMC-6236 perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the RMC-6236_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.140771 |
| SFTPA2 | surfactant protein A2 | 0.115864 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.104834 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0927466 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0924077 |
| FTL | ferritin, light polypeptide | 0.0764111 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0681426 |
| ENO1 | enolase 1, (alpha) | 0.0643188 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0591048 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0588909 |
| RPS3 | ribosomal protein S3 | 0.0579441 |
| TNS3 | tensin 3 | 0.0569092 |
| SQSTM1 | sequestosome 1 | 0.056749 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0494573 |
| RPS12 | ribosomal protein S12 | 0.0483471 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0472719 |
| B2M | beta-2-microglobulin | 0.0467186 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0433502 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0432441 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0425334 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0422939 |
| RPS2 | ribosomal protein S2 | 0.0405091 |
| PCBP2 | poly(rC) binding protein 2 | 0.038113 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0373565 |
| RNF213 | ring finger protein 213 | 0.0361084 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0356312 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0355655 |
| SET | SET nuclear proto-oncogene | 0.0350136 |
| RPS8 | ribosomal protein S8 | 0.0346994 |
| RPL37A | ribosomal protein L37a | 0.0341098 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.032366 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0323461 |
| AHNAK | AHNAK nucleoprotein | 0.031987 |
| RPL35A | ribosomal protein L35a | 0.0316821 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0309629 |
| RACK1 | receptor for activated C kinase 1 | 0.030597 |
| TXNRD1 | thioredoxin reductase 1 | 0.0300995 |
| DST | dystonin | 0.0299878 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0298863 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.02941 |
| ABLIM1 | actin binding LIM protein 1 | 0.0285777 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0282486 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 0.0279744 |
| MYOF | myoferlin | 0.0276345 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0272393 |
| RPL11 | ribosomal protein L11 | 0.0265549 |
| RPS17 | ribosomal protein S17 | 0.0265313 |
| COL5A2 | collagen, type V, alpha 2 | 0.0261664 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0260892 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0256981 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit | 0.0255809 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0255393 |
| RPS27A | ribosomal protein S27a | 0.0254124 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0253291 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.0252959 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0252849 |
| RPL9 | ribosomal protein L9 | 0.0248629 |
| FBL | fibrillarin | 0.024835 |
| LDHA | lactate dehydrogenase A | 0.0240436 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0236685 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0235432 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0233284 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0232298 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0230032 |
| HMOX1 | heme oxygenase 1 | 0.0229377 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0229038 |
| BRD2 | bromodomain containing 2 | 0.0228096 |
| ENAH | enabled homolog (Drosophila) | 0.0225749 |
| MYPN | myopalladin | 0.0219948 |
| VEGFA | vascular endothelial growth factor A | 0.021826 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.021805 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0217748 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.020957 |
| DSTN | destrin (actin depolymerizing factor) | 0.0208998 |
| CANX | calnexin | 0.0207878 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0204511 |
| LYST | lysosomal trafficking regulator | 0.0204179 |
| RPL26 | ribosomal protein L26 | 0.0203421 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0200105 |
| ADM | adrenomedullin | 0.0199928 |
| CENPF | centromere protein F, 350/400kDa | 0.0198596 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | 0.019803 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0194797 |
| ATXN1 | ataxin 1 | 0.0192931 |
| MFGE8 | milk fat globule-EGF factor 8 protein | 0.0189687 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0188401 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0188159 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0186807 |
| MED13L | mediator complex subunit 13-like | 0.0186637 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0182915 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.018177 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0179207 |
| MRTFA | myocardin related transcription factor A | 0.0179023 |
| TLN1 | talin 1 | 0.0175862 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.0175749 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0175529 |
| PERP | PERP, TP53 apoptosis effector | 0.0174584 |
| SLK | STE20-like kinase | 0.0174365 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.0174051 |
| PRDX1 | peroxiredoxin 1 | 0.0172847 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | -0.174261 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.174113 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.139212 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.129057 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.127283 |
| VIM | vimentin | -0.114288 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.109501 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.107207 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.104862 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.103568 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0960894 |
| ASPH | aspartate beta-hydroxylase | -0.0959358 |
| ACTN4 | actinin, alpha 4 | -0.0910551 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.090147 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0892266 |
| HMGA2 | high mobility group AT-hook 2 | -0.0876916 |
| JMJD1C | jumonji domain containing 1C | -0.0857984 |
| EGR1 | early growth response 1 | -0.0837991 |
| PDE10A | phosphodiesterase 10A | -0.0829984 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0829122 |
| RTN4 | reticulon 4 | -0.0821826 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0780313 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0777421 |
| MCL1 | myeloid cell leukemia 1 | -0.0765284 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0734052 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0716045 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.070627 |
| TMEM41B | transmembrane protein 41B | -0.0664736 |
| EFNA5 | ephrin-A5 | -0.0660099 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0636678 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0618329 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0605676 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0604687 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0598713 |
| PTK2 | protein tyrosine kinase 2 | -0.0588499 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0573689 |
| ATG7 | autophagy related 7 | -0.0564325 |
| CD44 | CD44 molecule (Indian blood group) | -0.055709 |
| NF1 | neurofibromin 1 | -0.0555143 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0550509 |
| FOSL1 | FOS-like antigen 1 | -0.0543195 |
| PLEKHG2 | pleckstrin homology domain containing, family G (with RhoGef domain) member 2 | -0.0530322 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0512662 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0497231 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0483252 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0482827 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0475475 |
| SMYD3 | SET and MYND domain containing 3 | -0.0473756 |
| SBF2 | SET binding factor 2 | -0.0472223 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0468818 |
| SNX14 | sorting nexin 14 | -0.0458991 |
| NAV2 | neuron navigator 2 | -0.0448469 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0441345 |
| RPS16 | ribosomal protein S16 | -0.0440492 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0437229 |
| ITGB5 | integrin, beta 5 | -0.0432354 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.042521 |
| MYO10 | myosin X | -0.0422588 |
| CDCP1 | CUB domain containing protein 1 | -0.0418479 |
| CARD18 | caspase recruitment domain family, member 18 | -0.0414925 |
| ATP13A3 | ATPase type 13A3 | -0.0413991 |
| DNMBP | dynamin binding protein | -0.0408749 |
| ANKRD11 | ankyrin repeat domain 11 | -0.040628 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0406265 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.040455 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0395436 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0394741 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0394115 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0392025 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0385043 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0384843 |
| NHSL1 | NHS-like 1 | -0.0382372 |
| CCND1 | cyclin D1 | -0.0376495 |
| RAB7A | RAB7A, member RAS oncogene family | -0.037591 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0371159 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0362763 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0353922 |
| BMERB1 | bMERB domain containing 1 | -0.0353057 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0351925 |
| VMP1 | vacuole membrane protein 1 | -0.0349977 |
| TMSB10 | thymosin beta 10 | -0.0349721 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | -0.0347191 |
| COG5 | component of oligomeric golgi complex 5 | -0.0346795 |
| CARS1 | cysteinyl-tRNA synthetase 1 | -0.0342879 |
| BMP6 | bone morphogenetic protein 6 | -0.0342281 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0340621 |
| FHL2 | four and a half LIM domains 2 | -0.0339071 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0333942 |
| FMNL2 | formin-like 2 | -0.0328653 |
| SAMD4B | sterile alpha motif domain containing 4B | -0.032782 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0322684 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0321646 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0321174 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0312724 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0300862 |
| SEPTIN9 | septin 9 | -0.0298974 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.029856 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | -0.029716 |
| SEPTIN10 | septin 10 | -0.0294633 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | -0.0291406 |
