| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | RMC-6236 perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the RMC-6236_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.182235 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.162854 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.159115 |
| KRT17 | keratin 17, type I | 0.119398 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0888339 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0850525 |
| B2M | beta-2-microglobulin | 0.0849169 |
| RACK1 | receptor for activated C kinase 1 | 0.0824701 |
| TMSB4X | thymosin beta 4, X-linked | 0.0707854 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0681769 |
| RPS3 | ribosomal protein S3 | 0.0672454 |
| DSPP | dentin sialophosphoprotein | 0.0626598 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0610605 |
| RPL12 | ribosomal protein L12 | 0.0610106 |
| ARRDC3 | arrestin domain containing 3 | 0.0604107 |
| PCBP2 | poly(rC) binding protein 2 | 0.0603347 |
| TXNIP | thioredoxin interacting protein | 0.059444 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0570574 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0566572 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0531766 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0514707 |
| BRD2 | bromodomain containing 2 | 0.0469566 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0459593 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0433568 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0429927 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0426361 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0424201 |
| ATF3 | activating transcription factor 3 | 0.0422294 |
| FAM107B | family with sequence similarity 107, member B | 0.0418024 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0412547 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0403891 |
| RPS2 | ribosomal protein S2 | 0.0403182 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0396722 |
| RPS8 | ribosomal protein S8 | 0.0378008 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0373687 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0358597 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0357609 |
| RPL26 | ribosomal protein L26 | 0.0352211 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0335251 |
| KRT7 | keratin 7, type II | 0.0326931 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0321249 |
| IRS2 | insulin receptor substrate 2 | 0.0312724 |
| RPS12 | ribosomal protein S12 | 0.0305979 |
| SQSTM1 | sequestosome 1 | 0.0304592 |
| SFTPA2 | surfactant protein A2 | 0.0303651 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0298607 |
| CFB | complement factor B | 0.0297932 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0296351 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0288443 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0285229 |
| RPS18 | ribosomal protein S18 | 0.0285064 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0284394 |
| GOLGB1 | golgin B1 | 0.0282664 |
| ATF4 | activating transcription factor 4 | 0.0277019 |
| CANX | calnexin | 0.0276301 |
| TPI1 | triosephosphate isomerase 1 | 0.0272698 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0272559 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0272329 |
| YBX3 | Y box binding protein 3 | 0.0271656 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.027146 |
| KLF6 | Kruppel-like factor 6 | 0.0270623 |
| IL6 | interleukin 6 | 0.026999 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0265308 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.025989 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0257895 |
| KLHL24 | kelch-like family member 24 | 0.0256436 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0249819 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0246754 |
| TMF1 | TATA element modulatory factor 1 | 0.0237716 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0237421 |
| SET | SET nuclear proto-oncogene | 0.0236283 |
| HSPA8 | heat shock 70kDa protein 8 | 0.023529 |
| RPS4X | ribosomal protein S4, X-linked | 0.0232392 |
| KIF5B | kinesin family member 5B | 0.0230243 |
| RPL3 | ribosomal protein L3 | 0.0228168 |
| RPL18 | ribosomal protein L18 | 0.0226353 |
| SON | SON DNA binding protein | 0.0223746 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0222726 |
| LAMB3 | laminin, beta 3 | 0.0222502 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0218703 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0217928 |
| PCDH1 | protocadherin 1 | 0.0217013 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0215694 |
| MX1 | MX dynamin-like GTPase 1 | 0.0214284 |
| CLDN1 | claudin 1 | 0.0214271 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0208271 |
| ADAR | adenosine deaminase, RNA-specific | 0.0207476 |
| RPS7 | ribosomal protein S7 | 0.0206432 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0204207 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0202399 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0201047 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0200248 |
| TPM3 | tropomyosin 3 | 0.0198025 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0197836 |
| JUN | jun proto-oncogene | 0.0197498 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0195586 |
| OPTN | optineurin | 0.0195048 |
| RPS27 | ribosomal protein S27 | 0.019441 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0194335 |
| AHR | aryl hydrocarbon receptor | 0.0194054 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.235087 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.112045 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.108729 |
| ASPH | aspartate beta-hydroxylase | -0.0992288 |
| LAMA4 | laminin, alpha 4 | -0.0917994 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0812611 |
| FN1 | fibronectin 1 | -0.0779447 |
| VCL | vinculin | -0.0750084 |
| PTMA | prothymosin, alpha | -0.0740269 |
| EMP1 | epithelial membrane protein 1 | -0.0734271 |
| RUNX1 | runt-related transcription factor 1 | -0.0708896 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.068609 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0676397 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0649911 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0647868 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0633224 |
| HMGA1 | high mobility group AT-hook 1 | -0.0616995 |
| ACTN4 | actinin, alpha 4 | -0.0611626 |
| LMO7 | LIM domain 7 | -0.058776 |
| TMSB10 | thymosin beta 10 | -0.0576782 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.0542268 |
| NDRG1 | N-myc downstream regulated 1 | -0.0538354 |
| EGR1 | early growth response 1 | -0.0513341 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0507871 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0501733 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0501405 |
| CD44 | CD44 molecule (Indian blood group) | -0.0498633 |
| RAD51B | RAD51 paralog B | -0.049231 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0476471 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0471875 |
| NF1 | neurofibromin 1 | -0.0469966 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0459448 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0457925 |
| SULF2 | sulfatase 2 | -0.0453035 |
| PTK2 | protein tyrosine kinase 2 | -0.0448551 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0447032 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0445441 |
| AFDN | afadin, adherens junction formation factor | -0.0437443 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | -0.0426444 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0418504 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.041493 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0414337 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0411126 |
| HMGA2 | high mobility group AT-hook 2 | -0.0406204 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0405625 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0403118 |
| RCOR1 | REST corepressor 1 | -0.0397524 |
| MECOM | MDS1 and EVI1 complex locus | -0.0392153 |
| CD2AP | CD2-associated protein | -0.0390935 |
| MUC4 | mucin 4, cell surface associated | -0.0390728 |
| ANXA2 | annexin A2 | -0.0383442 |
| SEPTIN9 | septin 9 | -0.0382881 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0376621 |
| ACTG1 | actin gamma 1 | -0.0372394 |
| SMYD3 | SET and MYND domain containing 3 | -0.0368319 |
| FLNB | filamin B, beta | -0.0365531 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.03622 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0360987 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0360576 |
| CMTM7 | CKLF-like MARVEL transmembrane domain containing 7 | -0.0357982 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0357398 |
| MEF2A | myocyte enhancer factor 2A | -0.0353652 |
| TMEM123 | transmembrane protein 123 | -0.0346263 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0343754 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0343506 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0335426 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0335186 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0330183 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0328088 |
| ANLN | anillin, actin binding protein | -0.032756 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0327323 |
| GNAS | GNAS complex locus | -0.0326865 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0323897 |
| FBXO11 | F-box protein 11 | -0.0322741 |
| INTS6 | integrator complex subunit 6 | -0.0322198 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0321989 |
| PARD3 | par-3 family cell polarity regulator | -0.0321797 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0320831 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0318468 |
| BCL2L1 | BCL2-like 1 | -0.0318273 |
| GATAD2A | GATA zinc finger domain containing 2A | -0.0316774 |
| LAMC2 | laminin, gamma 2 | -0.0312499 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0312263 |
| ERBIN | erbb2 interacting protein | -0.0311 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0309199 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0308479 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.030834 |
| FCHSD2 | FCH and double SH3 domains 2 | -0.03019 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0300888 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0300706 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0299199 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0296568 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0292679 |
| CCND1 | cyclin D1 | -0.0292347 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0292222 |
| KIAA1671 | KIAA1671 | -0.0289291 |
| TPM4 | tropomyosin 4 | -0.0288958 |
| SETD5 | SET domain containing 5 | -0.0287676 |
| DEK | DEK proto-oncogene | -0.0286701 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0284088 |
