| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | RMC-6236 perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the RMC-6236_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.145757 |
| IFI44L | interferon-induced protein 44-like | 0.0637256 |
| STC1 | stanniocalcin 1 | 0.0605952 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0574923 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0525515 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0470707 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0457577 |
| MMP2 | matrix metallopeptidase 2 | 0.0455646 |
| MX1 | MX dynamin-like GTPase 1 | 0.0433915 |
| ARRDC3 | arrestin domain containing 3 | 0.0416879 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0408283 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0405125 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.040412 |
| SP100 | SP100 nuclear antigen | 0.0378604 |
| CD109 | CD109 molecule | 0.0374563 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0323275 |
| HLA-E | major histocompatibility complex, class I, E | 0.0303575 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0301691 |
| PLIN2 | perilipin 2 | 0.029986 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0294037 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0291128 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0289151 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0285874 |
| FAT1 | FAT atypical cadherin 1 | 0.028574 |
| B2M | beta-2-microglobulin | 0.0275408 |
| SFTPA2 | surfactant protein A2 | 0.0252611 |
| SMAD3 | SMAD family member 3 | 0.024249 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0240348 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0240267 |
| SON | SON DNA binding protein | 0.0236368 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0236346 |
| VEGFA | vascular endothelial growth factor A | 0.0233665 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0229077 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0225801 |
| SSH1 | slingshot protein phosphatase 1 | 0.0223664 |
| TWIST2 | twist family bHLH transcription factor 2 | 0.0221719 |
| RUNX1 | runt-related transcription factor 1 | 0.0221405 |
| DSTN | destrin (actin depolymerizing factor) | 0.0221043 |
| SCARB2 | scavenger receptor class B, member 2 | 0.021571 |
| TMF1 | TATA element modulatory factor 1 | 0.0208254 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0205742 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0203461 |
| IFI44 | interferon-induced protein 44 | 0.0199872 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0196104 |
| EREG | epiregulin | 0.0194313 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | 0.0191616 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0188685 |
| PMP22 | peripheral myelin protein 22 | 0.0185959 |
| GOLGA4 | golgin A4 | 0.0185772 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0183768 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.0180966 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0176291 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0172796 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | 0.0172273 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) | 0.0169721 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.016881 |
| MX2 | MX dynamin-like GTPase 2 | 0.01674 |
| AHR | aryl hydrocarbon receptor | 0.0167101 |
| KLF6 | Kruppel-like factor 6 | 0.0164529 |
| ZNF638 | zinc finger protein 638 | 0.0163807 |
| KIF5B | kinesin family member 5B | 0.0163405 |
| DDX27 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 | 0.0161729 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0161591 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0161205 |
| PLSCR1 | phospholipid scramblase 1 | 0.0156081 |
| H1-0 | H1.0 linker histone | 0.0155727 |
| MYADM | myeloid-associated differentiation marker | 0.0152747 |
| DTX3L | deltex 3 like, E3 ubiquitin ligase | 0.0151392 |
| HDAC9 | histone deacetylase 9 | 0.0150475 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | 0.0147589 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | 0.0147358 |
| ADAR | adenosine deaminase, RNA-specific | 0.0147332 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0147277 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0145338 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0144954 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0144546 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0144361 |
| GOLGB1 | golgin B1 | 0.0143953 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0143475 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0143373 |
| SDF4 | stromal cell derived factor 4 | 0.0141655 |
| LYST | lysosomal trafficking regulator | 0.0141581 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.014126 |
| PHF3 | PHD finger protein 3 | 0.0140134 |
| SLFN5 | schlafen family member 5 | 0.0137427 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0137047 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0134875 |
| RDX | radixin | 0.0134191 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0133216 |
| PCBP2 | poly(rC) binding protein 2 | 0.0131827 |
| ATF4 | activating transcription factor 4 | 0.0130644 |
| SYNJ2 | synaptojanin 2 | 0.0130511 |
| PCM1 | pericentriolar material 1 | 0.0129914 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0128846 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0128492 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0128293 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0127964 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0127426 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0126913 |
| TTBK2 | tau tubulin kinase 2 | 0.0126823 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.243903 |
| HLA-B | major histocompatibility complex, class I, B | -0.172462 |
| VIM | vimentin | -0.161563 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.119316 |
| COL1A1 | collagen, type I, alpha 1 | -0.115582 |
| NDRG1 | N-myc downstream regulated 1 | -0.110331 |
| FN1 | fibronectin 1 | -0.0981108 |
| FRMD4A | FERM domain containing 4A | -0.0971739 |
| PTMA | prothymosin, alpha | -0.0962421 |
| COL1A2 | collagen, type I, alpha 2 | -0.0937432 |
| CDH13 | cadherin 13 | -0.089711 |
| TMSB10 | thymosin beta 10 | -0.0894548 |
| FTL | ferritin, light polypeptide | -0.0854055 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0822708 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0785007 |
| IER3 | immediate early response 3 | -0.0738668 |
| POTEF | POTE ankyrin domain family, member F | -0.0696946 |
| ASPH | aspartate beta-hydroxylase | -0.0665585 |
| COL6A1 | collagen, type VI, alpha 1 | -0.065529 |
| EGR1 | early growth response 1 | -0.0643148 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0622864 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0617465 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0614461 |
| CD44 | CD44 molecule (Indian blood group) | -0.0581975 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0555414 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0555357 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.055142 |
| APCDD1L | adenomatosis polyposis coli down-regulated 1-like | -0.0550643 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0535902 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0529422 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0522533 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0510467 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0501217 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.049963 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0499051 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0489424 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0488792 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.048324 |
| NAV1 | neuron navigator 1 | -0.0481746 |
| PKM | pyruvate kinase, muscle | -0.0472932 |
| ACTG1 | actin gamma 1 | -0.0470294 |
| S100A6 | S100 calcium binding protein A6 | -0.046367 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0448483 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0442651 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | -0.0441017 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0438135 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0431796 |
| MCL1 | myeloid cell leukemia 1 | -0.0423846 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0421277 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0421173 |
| RPL35A | ribosomal protein L35a | -0.0414291 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0412359 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0408597 |
| TPM4 | tropomyosin 4 | -0.0399198 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0396106 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0391557 |
| TNS3 | tensin 3 | -0.038622 |
| RPL31 | ribosomal protein L31 | -0.0384816 |
| HLA-C | major histocompatibility complex, class I, C | -0.0379913 |
| RPS6 | ribosomal protein S6 | -0.0377336 |
| GNAS | GNAS complex locus | -0.0377259 |
| HM13 | histocompatibility (minor) 13 | -0.0373378 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0370934 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0370466 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0367713 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0367642 |
| RPS21 | ribosomal protein S21 | -0.0366835 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0366075 |
| VCL | vinculin | -0.0361122 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0351618 |
| IL1B | interleukin 1, beta | -0.0349434 |
| VMP1 | vacuole membrane protein 1 | -0.0347478 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0342063 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.033946 |
| GLIS3 | GLIS family zinc finger 3 | -0.0339232 |
| MEF2A | myocyte enhancer factor 2A | -0.0338387 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0337728 |
| RPLP2 | ribosomal protein, large, P2 | -0.0333816 |
| RPLP1 | ribosomal protein, large, P1 | -0.0331495 |
| RPS25 | ribosomal protein S25 | -0.0330825 |
| FAM20C | family with sequence similarity 20, member C | -0.0330138 |
| RPS19 | ribosomal protein S19 | -0.0328595 |
| HPCAL1 | hippocalcin-like 1 | -0.0326528 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0325578 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.032523 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.032274 |
| COL5A1 | collagen, type V, alpha 1 | -0.0317466 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0315917 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0315284 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0309827 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0308662 |
| RPS16 | ribosomal protein S16 | -0.0306814 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0306759 |
| SETD5 | SET domain containing 5 | -0.0306757 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0302861 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0300846 |
| RPL34 | ribosomal protein L34 | -0.0296046 |
| S100A10 | S100 calcium binding protein A10 | -0.0295942 |
| CALR | calreticulin | -0.0295762 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0292024 |
