| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | RMC-6236 perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the RMC-6236_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.244676 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.141448 |
| HDAC9 | histone deacetylase 9 | 0.131732 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.118686 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0735155 |
| EZR | ezrin | 0.072832 |
| ANXA1 | annexin A1 | 0.0656124 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0627597 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0622222 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0561436 |
| EGFR | epidermal growth factor receptor | 0.0559871 |
| PCBP2 | poly(rC) binding protein 2 | 0.0517706 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0501761 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0485847 |
| PDGFC | platelet derived growth factor C | 0.0483719 |
| TMSB4X | thymosin beta 4, X-linked | 0.0440063 |
| RPS2 | ribosomal protein S2 | 0.0428756 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0412249 |
| RPL3 | ribosomal protein L3 | 0.0402668 |
| MACROD2 | MACRO domain containing 2 | 0.03839 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.036977 |
| RPS3 | ribosomal protein S3 | 0.0366147 |
| RACK1 | receptor for activated C kinase 1 | 0.0365741 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0353955 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0345553 |
| ZNF608 | zinc finger protein 608 | 0.0337459 |
| B2M | beta-2-microglobulin | 0.0325029 |
| RPS6 | ribosomal protein S6 | 0.0321278 |
| ATF4 | activating transcription factor 4 | 0.0319129 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0312167 |
| RPS8 | ribosomal protein S8 | 0.030694 |
| SON | SON DNA binding protein | 0.0301994 |
| SFTPA2 | surfactant protein A2 | 0.0296368 |
| RPL12 | ribosomal protein L12 | 0.0264202 |
| RPL26 | ribosomal protein L26 | 0.0254757 |
| RPS12 | ribosomal protein S12 | 0.0249845 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0246314 |
| RPS14 | ribosomal protein S14 | 0.0228734 |
| MYO5C | myosin VC | 0.0225704 |
| RPS27 | ribosomal protein S27 | 0.0223413 |
| AMOTL2 | angiomotin like 2 | 0.0217217 |
| JUN | jun proto-oncogene | 0.0216112 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0214299 |
| CLU | clusterin | 0.0214111 |
| YBX1 | Y box binding protein 1 | 0.0212084 |
| PNN | pinin, desmosome associated protein | 0.0211515 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0208012 |
| SET | SET nuclear proto-oncogene | 0.0205284 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0201767 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0200297 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0199861 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | 0.0198968 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0198061 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0197602 |
| RPS17 | ribosomal protein S17 | 0.0196942 |
| RHOB | ras homolog family member B | 0.019399 |
| WDR43 | WD repeat domain 43 | 0.0192844 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0192663 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.019225 |
| TXNIP | thioredoxin interacting protein | 0.0191042 |
| BRD2 | bromodomain containing 2 | 0.0190712 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0189463 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0184157 |
| DSTN | destrin (actin depolymerizing factor) | 0.0182116 |
| PLK2 | polo-like kinase 2 | 0.0181177 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0180151 |
| RPS4X | ribosomal protein S4, X-linked | 0.01793 |
| FER1L6 | fer-1-like family member 6 | 0.0178912 |
| RPS3A | ribosomal protein S3A | 0.017882 |
| DIAPH1 | diaphanous-related formin 1 | 0.0178768 |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta | 0.0178222 |
| RPS18 | ribosomal protein S18 | 0.0176468 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.017577 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0169561 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0168869 |
| HECA | headcase homolog (Drosophila) | 0.0166616 |
| RPL36 | ribosomal protein L36 | 0.0165773 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0164719 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.0164604 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0162361 |
| RPL18 | ribosomal protein L18 | 0.015868 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0151766 |
| GATA6 | GATA binding protein 6 | 0.0149497 |
| PLCE1 | phospholipase C, epsilon 1 | 0.0148727 |
| SGMS2 | sphingomyelin synthase 2 | 0.0147856 |
| TLN1 | talin 1 | 0.0143332 |
| KIF5C | kinesin family member 5C | 0.0141755 |
| NRDC | nardilysin convertase | 0.0141453 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0138701 |
| TPM3 | tropomyosin 3 | 0.0138136 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0135961 |
| RPL27 | ribosomal protein L27 | 0.013571 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0135661 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0135113 |
| DAPK3 | death-associated protein kinase 3 | 0.0135067 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.0133625 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0132904 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | 0.0132675 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0130733 |
| RPL23 | ribosomal protein L23 | 0.012868 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.314867 |
| PTMA | prothymosin, alpha | -0.140933 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.120231 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.120013 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.108615 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.10443 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.104016 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0917971 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0908942 |
| VCL | vinculin | -0.0864198 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0807382 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0691086 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0643847 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0636462 |
| NFIA | nuclear factor I/A | -0.0613905 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0613353 |
| BMP10 | bone morphogenetic protein 10 | -0.0606587 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0578391 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0550072 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0548487 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0543327 |
| PARD3 | par-3 family cell polarity regulator | -0.0539638 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.053512 |
| NBEA | neurobeachin | -0.0517191 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0514677 |
| MSI2 | musashi RNA-binding protein 2 | -0.0514394 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0513779 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0505619 |
| EVI5 | ecotropic viral integration site 5 | -0.0505172 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0504757 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0492926 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.046797 |
| FOXP1 | forkhead box P1 | -0.0467963 |
| DENND1A | DENN/MADD domain containing 1A | -0.0442546 |
| RBM39 | RNA binding motif protein 39 | -0.0439003 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0438604 |
| PRELID2 | PRELI domain containing 2 | -0.0438261 |
| ECT2 | epithelial cell transforming 2 | -0.043798 |
| NEBL | nebulette | -0.0435156 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0430705 |
| S100A6 | S100 calcium binding protein A6 | -0.0419935 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0403001 |
| PYGB | phosphorylase, glycogen; brain | -0.0394013 |
| EFNA5 | ephrin-A5 | -0.0393522 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.039126 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.038651 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.0385185 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0383226 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0378591 |
| GLI2 | GLI family zinc finger 2 | -0.037859 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0374166 |
| ACTG1 | actin gamma 1 | -0.0373281 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0369351 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0368351 |
| FLNB | filamin B, beta | -0.036498 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0362894 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0348622 |
| GPHN | gephyrin | -0.0346821 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0340497 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0338768 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0337968 |
| SMNDC1 | survival motor neuron domain containing 1 | -0.0335939 |
| CDC73 | cell division cycle 73 | -0.0335263 |
| FUS | FUS RNA binding protein | -0.0330298 |
| FHIT | fragile histidine triad | -0.0329775 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0328742 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.0328025 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0326953 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0323051 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0322974 |
| TCF12 | transcription factor 12 | -0.0317367 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0314109 |
| AHNAK | AHNAK nucleoprotein | -0.0311927 |
| DIAPH2 | diaphanous-related formin 2 | -0.0311187 |
| KIAA1958 | KIAA1958 | -0.031027 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.030982 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0309257 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.0306657 |
| SBF2 | SET binding factor 2 | -0.0306356 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0304235 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0302705 |
| SMYD3 | SET and MYND domain containing 3 | -0.0301891 |
| HJURP | Holliday junction recognition protein | -0.030086 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0300598 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0299704 |
| NF1 | neurofibromin 1 | -0.0296768 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0296311 |
| CALU | calumenin | -0.0296278 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0295118 |
| ADNP | activity-dependent neuroprotector homeobox | -0.029312 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0290909 |
| FBXO11 | F-box protein 11 | -0.029067 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0287624 |
| ASPH | aspartate beta-hydroxylase | -0.0286027 |
| GPATCH8 | G patch domain containing 8 | -0.0283795 |
| PTK2 | protein tyrosine kinase 2 | -0.0283305 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.0282027 |
| JMJD1C | jumonji domain containing 1C | -0.0280875 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0280088 |
| QKI | QKI, KH domain containing, RNA binding | -0.0280045 |
