RNA polymerase I upstream activating factor complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025
Category structural or functional annotations
Type cellular component
External Link http://amigo.geneontology.org/amigo/term/GO:0000500
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363 proteins co-occuring with the RNA polymerase I upstream activating factor complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.

Symbol Name Standardized Value
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) 3.129
POLI polymerase (DNA directed) iota 2.827
TAF1B TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa 2.324
POLR1G RNA polymerase I subunit G 2.283
POLR1F RNA polymerase I subunit F 2.213
WDR48 WD repeat domain 48 2.174
USP1 ubiquitin specific peptidase 1 2.146
POLR1H RNA polymerase I subunit H 2.128
UBTF upstream binding transcription factor, RNA polymerase I 2.091
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa 2.089
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa 2.083
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa 2.047
POLR1E polymerase (RNA) I polypeptide E, 53kDa 2.008
POLR1B polymerase (RNA) I polypeptide B, 128kDa 1.927
TBP TATA box binding protein 1.883
SIRT2 sirtuin 2 1.842
GTF2B general transcription factor IIB 1.788
TCEA2 transcription elongation factor A (SII), 2 1.733
TCEA3 transcription elongation factor A (SII), 3 1.724
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa 1.718
TCEA1 transcription elongation factor A (SII), 1 1.673
FANCD2 Fanconi anemia, complementation group D2 1.597
TTF1 transcription termination factor, RNA polymerase I 1.545
SIRT1 sirtuin 1 1.517
CDC14A cell division cycle 14A 1.513
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa 1.507
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa 1.488
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB 1.474
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa 1.462
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit 1.444
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa 1.443
NTS neurotensin 1.425
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae) 1.415
FAAP24 FA core complex associated protein 24 1.398
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa 1.349
FBL fibrillarin 1.33
NOP56 NOP56 ribonucleoprotein 1.33
SUPT4H1 suppressor of Ty 4 homolog 1 (S. cerevisiae) 1.325
POLR2H polymerase (RNA) II (DNA directed) polypeptide H 1.315
POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa 1.311
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa 1.306
NANOS1 nanos homolog 1 (Drosophila) 1.286
LSG1 large 60S subunit nuclear export GTPase 1 1.247
TOP1 topoisomerase (DNA) I 1.244
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase 1.236
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa 1.226
H2BC21 H2B clustered histone 21 1.221
ZUP1 zinc finger containing ubiquitin peptidase 1 1.214
H2AC20 H2A clustered histone 20 1.212
H2AC19 H2A clustered histone 19 1.211
USP12 ubiquitin specific peptidase 12 1.209
RPA3 replication protein A3, 14kDa 1.191
TXNL4B thioredoxin-like 4B 1.189
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa 1.176
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) 1.175
POLR2F polymerase (RNA) II (DNA directed) polypeptide F 1.171
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 1.155
CLCF1 cardiotrophin-like cytokine factor 1 1.151
BOLL boule-like RNA-binding protein 1.15
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) 1.147
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase 1.146
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa 1.143
POLR1D polymerase (RNA) I polypeptide D, 16kDa 1.137
CHD1 chromodomain helicase DNA binding protein 1 1.136
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1 1.13
HPSE2 heparanase 2 (inactive) 1.127
PNKD paroxysmal nonkinesigenic dyskinesia 1.123
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide 1.115
MYBBP1A MYB binding protein (P160) 1a 1.115
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 1.093
POLR2G polymerase (RNA) II (DNA directed) polypeptide G 1.073
POLR1A polymerase (RNA) I polypeptide A, 194kDa 1.063
TRIM28 tripartite motif containing 28 1.053
PPAN-P2RY11 PPAN-P2RY11 readthrough 1.043
FANCM Fanconi anemia, complementation group M 1.043
HDAC8 histone deacetylase 8 1.039
FANCI Fanconi anemia, complementation group I 1.036
USP24 ubiquitin specific peptidase 24 1.034
WDR20 WD repeat domain 20 1.033
FPR3 formyl peptide receptor 3 1.031
CD300LD CD300 molecule-like family member d 1.03
MTREX Mtr4 exosome RNA helicase 1.025
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa 1.023
UBE2T ubiquitin-conjugating enzyme E2T 1.022
HIPK3 homeodomain interacting protein kinase 3 1.02
RIMS1 regulating synaptic membrane exocytosis 1 1.015
H4C7 H4 clustered histone 7 1.015
GTF3A general transcription factor IIIA 1.014
H4C15 H4 clustered histone 15 0.997
POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa 0.986
FANCC Fanconi anemia, complementation group C 0.983
HDHD5 haloacid dehalogenase like hydrolase domain containing 5 0.981
H3-3B H3.3 histone B 0.979
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa 0.978
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 0.976
SPRTN SprT-like N-terminal domain 0.976
H3-7 H3.7 histone (putative) 0.963
H3-5 H3.5 histone 0.962
H3C13 H3 clustered histone 13 0.962
H3-4 H3.4 histone, cluster member 0.961
NOP2 NOP2 nucleolar protein 0.958
MYC v-myc avian myelocytomatosis viral oncogene homolog 0.958
FBF1 Fas (TNFRSF6) binding factor 1 0.956
CFAP20 cilia and flagella associated protein 20 0.956
H3C7 H3 clustered histone 7 0.954
MED17 mediator complex subunit 17 0.954
KAT2B K(lysine) acetyltransferase 2B 0.953
EXOSC10 exosome component 10 0.947
THOP1 thimet oligopeptidase 1 0.943
REXO5 RNA exonuclease 5 0.94
USP5 ubiquitin specific peptidase 5 (isopeptidase T) 0.939
ORC5 origin recognition complex, subunit 5 0.935
PCNA proliferating cell nuclear antigen 0.932
TBCE tubulin folding cofactor E 0.931
TSC2 tuberous sclerosis 2 0.931
USP36 ubiquitin specific peptidase 36 0.929
PROP1 PROP paired-like homeobox 1 0.928
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.921
FANCL Fanconi anemia, complementation group L 0.92
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.916
KAT2A K(lysine) acetyltransferase 2A 0.91
FAM53B family with sequence similarity 53, member B 0.908
SLX9 SLX9 ribosome biogenesis factor 0.906
USP2 ubiquitin specific peptidase 2 0.906
USP9X ubiquitin specific peptidase 9, X-linked 0.904
PCLAF PCNA clamp associated factor 0.898
USP25 ubiquitin specific peptidase 25 0.895
USP6 ubiquitin specific peptidase 6 0.887
CHD7 chromodomain helicase DNA binding protein 7 0.887
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast) 0.883
RHEB Ras homolog enriched in brain 0.883
SPATA5L1 spermatogenesis associated 5-like 1 0.878
BANF1 barrier to autointegration factor 1 0.875
ISYNA1 inositol-3-phosphate synthase 1 0.873
ERLEC1 endoplasmic reticulum lectin 1 0.871
ZNF107 zinc finger protein 107 0.866
LRRC47 leucine rich repeat containing 47 0.864
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 0.863
TP53 tumor protein p53 0.863
PCF11 PCF11 cleavage and polyadenylation factor subunit 0.863
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) 0.86
LBR lamin B receptor 0.86
SF1 splicing factor 1 0.859
MED29 mediator complex subunit 29 0.857
RPL6 ribosomal protein L6 0.851
ACP7 acid phosphatase 7, tartrate resistant (putative) 0.85
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 0.848
TCOF1 Treacher Collins-Franceschetti syndrome 1 0.847
TOP3A topoisomerase (DNA) III alpha 0.845
ANGPTL2 angiopoietin-like 2 0.84
EIF1AD eukaryotic translation initiation factor 1A domain containing 0.84
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 0.84
FAAP100 FA core complex associated protein 100 0.838
BCL2A1 BCL2-related protein A1 0.834
CENPV centromere protein V 0.83
UNC93B1 unc-93 homolog B1 (C. elegans) 0.827
HDAC3 histone deacetylase 3 0.826
CAPSL calcyphosine-like 0.825
DKC1 dyskeratosis congenita 1, dyskerin 0.818
TBC1D7 TBC1 domain family, member 7 0.817
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 0.81
EEF2K eukaryotic elongation factor 2 kinase 0.805
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.8
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.8
POLL polymerase (DNA directed), lambda 0.799
MED18 mediator complex subunit 18 0.799
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa 0.796
LTV1 LTV1 ribosome biogenesis factor 0.796
HOXB4 homeobox B4 0.795
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 0.79
HDAC2 histone deacetylase 2 0.783
LSM1 LSM1, U6 small nuclear RNA associated 0.781
PUM3 pumilio RNA binding family member 3 0.78
HLA-F major histocompatibility complex, class I, F 0.78
PDCD2L programmed cell death 2-like 0.778
USF1 upstream transcription factor 1 0.777
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa 0.775
NOP58 NOP58 ribonucleoprotein 0.765
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 0.763
NPR1 natriuretic peptide receptor 1 0.763
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) 0.76
ERCC3 excision repair cross-complementation group 3 0.757
USF2 upstream transcription factor 2, c-fos interacting 0.757
PDCD5 programmed cell death 5 0.757
USP8 ubiquitin specific peptidase 8 0.756
CUBN cubilin (intrinsic factor-cobalamin receptor) 0.753
PGC progastricsin (pepsinogen C) 0.753
DES desmin 0.745
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa 0.744
GPR160 G protein-coupled receptor 160 0.743
BCLAF1 BCL2-associated transcription factor 1 0.74
RPTOR regulatory associated protein of MTOR, complex 1 0.739
RASL11A RAS-like, family 11, member A 0.739
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 0.739
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.733
RMI1 RecQ mediated genome instability 1 0.732
HDAC1 histone deacetylase 1 0.732
RAB18 RAB18, member RAS oncogene family 0.729
RPL39 ribosomal protein L39 0.728
NOP10 NOP10 ribonucleoprotein 0.724
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 0.723
EN1 engrailed homeobox 1 0.722
VSIR V-set immunoregulatory receptor 0.721
INS insulin 0.716
RPS4X ribosomal protein S4, X-linked 0.714
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 0.714
NOP53 NOP53 ribosome biogenesis factor 0.712
GPX6 glutathione peroxidase 6 0.709
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa 0.709
GPX5 glutathione peroxidase 5 0.708
GPX8 glutathione peroxidase 8 (putative) 0.707
GPX7 glutathione peroxidase 7 0.704
RAD51 RAD51 recombinase 0.702
MT4 metallothionein 4 0.701
RPL27A ribosomal protein L27a 0.698
GPX2 glutathione peroxidase 2 0.697
SERF2 small EDRK-rich factor 2 0.693
PTPRJ protein tyrosine phosphatase, receptor type, J 0.693
POLK polymerase (DNA directed) kappa 0.692
GPX3 glutathione peroxidase 3 0.69
UTP11 UTP11 small subunit processome component 0.69
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa 0.687
TM2D3 TM2 domain containing 3 0.682
SLCO6A1 solute carrier organic anion transporter family, member 6A1 0.682
AMN amnion associated transmembrane protein 0.681
ACTR8 ARP8 actin-related protein 8 homolog (yeast) 0.681
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 0.681
CDC16 cell division cycle 16 0.679
RAD52 RAD52 homolog (S. cerevisiae) 0.679
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.676
CHEK1 checkpoint kinase 1 0.676
PDCD11 programmed cell death 11 0.675
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 0.675
ECD ecdysoneless homolog (Drosophila) 0.669
BRIP1 BRCA1 interacting protein C-terminal helicase 1 0.668
MYOC myocilin, trabecular meshwork inducible glucocorticoid response 0.666
DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2) 0.661
ZFP64 ZFP64 zinc finger protein 0.661
NOB1 NIN1/RPN12 binding protein 1 homolog (S. cerevisiae) 0.658
AK6 adenylate kinase 6 0.657
FANCE Fanconi anemia, complementation group E 0.657
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 0.656
CARD18 caspase recruitment domain family, member 18 0.653
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 0.653
ZNF622 zinc finger protein 622 0.651
CCND1 cyclin D1 0.65
CLSTN1 calsyntenin 1 0.648
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa 0.648
STK11 serine/threonine kinase 11 0.648
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 0.648
CLSPN claspin 0.647
RPL23A ribosomal protein L23a 0.647
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 0.645
SLC38A3 solute carrier family 38, member 3 0.644
SBDS Shwachman-Bodian-Diamond syndrome 0.643
CBX8 chromobox homolog 8 0.642
TSR3 TSR3, 20S rRNA accumulation, homolog (S. cerevisiae) 0.641
MED20 mediator complex subunit 20 0.641
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 0.641
RTF2 replication termination factor 2 0.64
USP3 ubiquitin specific peptidase 3 0.64
NOL10 nucleolar protein 10 0.639
ZNF587 zinc finger protein 587 0.637
NVL nuclear VCP-like 0.634
RTP3 receptor (chemosensory) transporter protein 3 0.631
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 0.629
SESN2 sestrin 2 0.629
DAZ1 deleted in azoospermia 1 0.628
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 0.626
EEPD1 endonuclease/exonuclease/phosphatase family domain containing 1 0.624
MRPL37 mitochondrial ribosomal protein L37 0.624
KMT5C lysine methyltransferase 5C 0.623
CDK19 cyclin-dependent kinase 19 0.622
IL6 interleukin 6 0.618
MRPS36 mitochondrial ribosomal protein S36 0.617
MAF1 MAF1 homolog (S. cerevisiae) 0.617
TEX2 testis expressed 2 0.615
SLX1A SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae) 0.611
ZDBF2 zinc finger, DBF-type containing 2 0.609
POLR2D polymerase (RNA) II (DNA directed) polypeptide D 0.606
BRCC3 BRCA1/BRCA2-containing complex, subunit 3 0.605
PHF23 PHD finger protein 23 0.604
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.601
CDK12 cyclin-dependent kinase 12 0.6
DDIT4 DNA-damage-inducible transcript 4 0.598
MAL2 mal, T-cell differentiation protein 2 (gene/pseudogene) 0.598
PTEN phosphatase and tensin homolog 0.598
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.597
BCL2L1 BCL2-like 1 0.596
MAK16 MAK16 homolog (S. cerevisiae) 0.595
GSR glutathione reductase 0.594
CDK9 cyclin-dependent kinase 9 0.594
ATRAID all-trans retinoic acid-induced differentiation factor 0.593
FANCF Fanconi anemia, complementation group F 0.593
ATM ATM serine/threonine kinase 0.588
RBP5 retinol binding protein 5, cellular 0.588
INTS4 integrator complex subunit 4 0.587
MCL1 myeloid cell leukemia 1 0.587
SIRT7 sirtuin 7 0.587
NRDC nardilysin convertase 0.586
RRH retinal pigment epithelium-derived rhodopsin homolog 0.585
NOLC1 nucleolar and coiled-body phosphoprotein 1 0.585
MED24 mediator complex subunit 24 0.584
ITCH itchy E3 ubiquitin protein ligase 0.584
BCL2 B-cell CLL/lymphoma 2 0.582
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.58
ITGB4 integrin, beta 4 0.58
PAK1IP1 PAK1 interacting protein 1 0.578
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa 0.576
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 0.571
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.568
BRCA1 breast cancer 1, early onset 0.566
CDK17 cyclin-dependent kinase 17 0.565
MMP10 matrix metallopeptidase 10 0.562
PMEL premelanosome protein 0.561
CCNL2 cyclin L2 0.56
IL1R2 interleukin 1 receptor, type II 0.558
IRS1 insulin receptor substrate 1 0.557
KRT71 keratin 71, type II 0.555
HYPK huntingtin interacting protein K 0.555
MSI1 musashi RNA-binding protein 1 0.55
INTS7 integrator complex subunit 7 0.549
OOEP oocyte expressed protein 0.548
USP11 ubiquitin specific peptidase 11 0.548
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.547
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 0.546
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast) 0.545
EFL1 elongation factor like GTPase 1 0.544
TEX10 testis expressed 10 0.539
MYLK myosin light chain kinase 0.538
PWP1 PWP1 homolog (S. cerevisiae) 0.538
MKRN2 makorin ring finger protein 2 0.535
WDR3 WD repeat domain 3 0.534
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 0.534
SLC13A5 solute carrier family 13 (sodium-dependent citrate transporter), member 5 0.533
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) 0.532
MED22 mediator complex subunit 22 0.531
EMG1 EMG1 N1-specific pseudouridine methyltransferase 0.531
IL1B interleukin 1, beta 0.531
EME2 essential meiotic structure-specific endonuclease subunit 2 0.529
CNOT1 CCR4-NOT transcription complex, subunit 1 0.529
RPL11 ribosomal protein L11 0.529
USP28 ubiquitin specific peptidase 28 0.527
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa 0.527
CARD6 caspase recruitment domain family, member 6 0.524
FLII flightless I homolog (Drosophila) 0.521
RPL5 ribosomal protein L5 0.52
NOL9 nucleolar protein 9 0.52
PGP phosphoglycolate phosphatase 0.518
MAN1C1 mannosidase, alpha, class 1C, member 1 0.518
MRPL41 mitochondrial ribosomal protein L41 0.515
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) 0.513
MFAP1 microfibrillar-associated protein 1 0.512
USP4 ubiquitin specific peptidase 4 (proto-oncogene) 0.512
LIN9 lin-9 DREAM MuvB core complex component 0.508
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.507
POTEF POTE ankyrin domain family, member F 0.507
BORCS6 BLOC-1 related complex subunit 6 0.505
ACE angiotensin I converting enzyme 0.505
BARD1 BRCA1 associated RING domain 1 0.503
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa 0.502
RRP7A ribosomal RNA processing 7 homolog A (S. cerevisiae) 0.502
FPR2 formyl peptide receptor 2 0.501