RND1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description Rho family GTPase 1|This gene encodes a protein that belongs to the Rho GTPase family. Members of this family regulate the organization of the actin cytoskeleton in response to extracellular growth factors. A similar protein in rat interacts with a microtubule regulator to control axon extension. [provided by RefSeq, Apr 2014] (NCBI Entrez Gene Database, 27289)
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Genes

363 genes differentially expressed following the RND1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
ZNF491 zinc finger protein 491 3.3411
TOMM20L translocase of outer mitochondrial membrane 20 homolog (yeast)-like 3.3411
RIMBP2 RIMS binding protein 2 3.3411
MTTP microsomal triglyceride transfer protein 3.3411
PAX7 paired box 7 3.3411
C6ORF58 chromosome 6 open reading frame 58 3.3411
MANSC4 MANSC domain containing 4 3.3411
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13 3.3411
PBOV1 prostate and breast cancer overexpressed 1 3.3411
SLC39A4 solute carrier family 39 (zinc transporter), member 4 3.3411
BIRC3 baculoviral IAP repeat containing 3 3.3411
OSGIN1 oxidative stress induced growth inhibitor 1 3.3411
HES4 hes family bHLH transcription factor 4 3.3411
MBLAC1 metallo-beta-lactamase domain containing 1 3.3411
GPR55 G protein-coupled receptor 55 3.3411
SLC26A7 solute carrier family 26 (anion exchanger), member 7 3.3411
SLC26A4 solute carrier family 26 (anion exchanger), member 4 3.3411
XAF1 XIAP associated factor 1 3.3411
ALOX15 arachidonate 15-lipoxygenase 3.3411
BTN1A1 butyrophilin, subfamily 1, member A1 3.3411
NANOS3 nanos homolog 3 (Drosophila) 3.3411
ZEB2 zinc finger E-box binding homeobox 2 3.3411
PCDHB1 protocadherin beta 1 3.3411
WNT3A wingless-type MMTV integration site family, member 3A 3.3411
AVPR2 arginine vasopressin receptor 2 3.3411
TRPV6 transient receptor potential cation channel, subfamily V, member 6 3.3411
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit 3.3411
BFSP2 beaded filament structural protein 2, phakinin 3.3411
IL2RB interleukin 2 receptor, beta 3.3411
TAS2R13 taste receptor, type 2, member 13 3.3411
BMP3 bone morphogenetic protein 3 3.3411
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 3.3411
IKZF3 IKAROS family zinc finger 3 (Aiolos) 3.3411
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 3.3411
GPAT2 glycerol-3-phosphate acyltransferase 2, mitochondrial 3.3411
LOC102724877 uncharacterized LOC102724877 3.3411
RFX6 regulatory factor X, 6 3.3411
SPINK14 serine peptidase inhibitor, Kazal type 14 (putative) 3.3411
NPIPA8 nuclear pore complex interacting protein family, member A8 3.3411
HAS1 hyaluronan synthase 1 3.3411
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa 3.3411
C1ORF141 chromosome 1 open reading frame 141 3.3411
FSCN3 fascin actin-bundling protein 3, testicular 3.3411
GMFG glia maturation factor, gamma 3.3411
TMEM217 transmembrane protein 217 3.3411
PRSS36 protease, serine, 36 3.3411
YY2 YY2 transcription factor 3.3411
COPZ2 coatomer protein complex, subunit zeta 2 3.3411
LGR6 leucine-rich repeat containing G protein-coupled receptor 6 3.3411
STAP1 signal transducing adaptor family member 1 3.3411
LOC124901449 uncharacterized LOC124901449 3.3411
MT4 metallothionein 4 3.3411
AVPR1A arginine vasopressin receptor 1A 3.3411
OPRM1 opioid receptor, mu 1 3.3411
GPR35 G protein-coupled receptor 35 3.3411
ANO3 anoctamin 3 3.3411
PROZ protein Z, vitamin K-dependent plasma glycoprotein 3.3411
TMEM40 transmembrane protein 40 3.3411
MYEOV myeloma overexpressed 3.3411
MIOX myo-inositol oxygenase 3.3411
TTR transthyretin 3.3411
EIF2S3B eukaryotic translation initiation factor 2 subunit gamma B 3.3411
ODAD1 outer dynein arm docking complex subunit 1 3.3411
CPHXL2 cytoplasmic polyadenylated homeobox like 2 3.3411
COXFA4L2 cytochrome c oxidase hypoxia associated subunit FA4L2 3.3411
SPEM3 SPEM family member 3 3.3411
RPS21-DT RPS21 divergent transcript 3.3411
CSP2 CS pseudogene 2 3.3411
NHERF4 NHERF family PDZ scaffold protein 4 3.3411
LOC124903233 uncharacterized LOC124903233 3.3411
LOC124902436 talanin 3.3411
CFAP276 cilia and flagella associated protein 276 3.3411
ERFE erythroferrone 3.3411
TBXT T-box transcription factor T 3.3411
SMTNL2 smoothelin-like 2 3.3411
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 3.3411
CHRD chordin 3.3411
STAC SH3 and cysteine rich domain 3.3411
PRB3 proline-rich protein BstNI subfamily 3 3.3411
NKX3-2 NK3 homeobox 2 3.3411
NRN1 neuritin 1 3.3411
STKLD1 serine/threonine kinase-like domain containing 1 3.3411
CD5 CD5 molecule 3.3411
INHBC inhibin, beta C 3.3411
IL11RA interleukin 11 receptor, alpha 3.3411
PARP3 poly (ADP-ribose) polymerase family, member 3 3.3411
OR6C1 olfactory receptor, family 6, subfamily C, member 1 3.3411
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 3.3411
CD48 CD48 molecule 3.3411
PARVG parvin, gamma 3.3411
NPIPB8 nuclear pore complex interacting protein family, member B8 3.3411
NPIPB6 nuclear pore complex interacting protein family, member B6 3.3411
GDF9 growth differentiation factor 9 3.3411
PABPC1L2A poly(A) binding protein, cytoplasmic 1-like 2A 3.3411
STARD6 StAR-related lipid transfer (START) domain containing 6 3.3411
S100B S100 calcium binding protein B 3.3411
CCR9 chemokine (C-C motif) receptor 9 3.3411
MYH13 myosin, heavy chain 13, skeletal muscle 3.3411
IL6 interleukin 6 3.3411
DNAJC5G DnaJ (Hsp40) homolog, subfamily C, member 5 gamma 3.3411
RUFY4 RUN and FYVE domain containing 4 3.3411
SLCO2A1 solute carrier organic anion transporter family, member 2A1 3.3411
BTNL8 butyrophilin-like 8 3.3411
ADORA3 adenosine A3 receptor 3.3411
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18 3.3411
CXCR2 chemokine (C-X-C motif) receptor 2 3.3411
SLC47A2 solute carrier family 47 (multidrug and toxin extrusion), member 2 3.3411
CLEC4D C-type lectin domain family 4, member D 3.3411
PSKH2 protein serine kinase H2 3.3411
MAB21L3 mab-21-like 3 (C. elegans) 3.3411
FAM209B family with sequence similarity 209, member B 3.3411
SYNE3 spectrin repeat containing, nuclear envelope family member 3 3.3411
LCNL1 lipocalin-like 1 3.3411
IL12A interleukin 12A 3.3411
GPR50 G protein-coupled receptor 50 3.3411
TMEM150B transmembrane protein 150B 3.3411
ERMN ermin, ERM-like protein 3.3411
TBPL2 TATA box binding protein like 2 3.3411
MBOAT4 membrane bound O-acyltransferase domain containing 4 3.3411
APOF apolipoprotein F 3.3411
ERICH6 glutamate-rich 6 3.3411
DCLK3 doublecortin-like kinase 3 3.3411
RAB40A RAB40A, member RAS oncogene family 3.3411
C22ORF42 chromosome 22 open reading frame 42 3.3411
C2CD4B C2 calcium-dependent domain containing 4B 3.3411
DND1 DND microRNA-mediated repression inhibitor 1 3.3411
TMPPE transmembrane protein with metallophosphoesterase domain 3.3411
CCNI2 cyclin I family, member 2 3.3411
PFN4 profilin family, member 4 3.3411
CFAP126 cilia and flagella associated protein 126 3.3411
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 3.3411
IL25 interleukin 25 3.3411
GPRC6A G protein-coupled receptor, class C, group 6, member A 3.3411
GBX1 gastrulation brain homeobox 1 3.3411
LMX1A LIM homeobox transcription factor 1, alpha 3.3411
FCRLB Fc receptor-like B 3.3411
NT5DC4 5'-nucleotidase domain containing 4 3.3411
NUPR1 nuclear protein, transcriptional regulator, 1 3.3411
MCCD1 mitochondrial coiled-coil domain 1 3.3411
EVPLL envoplakin-like 3.3411
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 3.3411
PPP1R14C protein phosphatase 1, regulatory (inhibitor) subunit 14C 3.3411
KLK11 kallikrein-related peptidase 11 3.3411
TTC16 tetratricopeptide repeat domain 16 3.3411
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 3.3411
ARL13A ADP-ribosylation factor-like 13A 3.3411
ZC3H12D zinc finger CCCH-type containing 12D 3.3411
CCDC177 coiled-coil domain containing 177 3.3411
PIK3R6 phosphoinositide-3-kinase, regulatory subunit 6 3.3411
CACNG3 calcium channel, voltage-dependent, gamma subunit 3 3.3411
PSG8 pregnancy specific beta-1-glycoprotein 8 3.3411
APOL5 apolipoprotein L, 5 3.3411
OR14A2 olfactory receptor, family 14, subfamily A, member 2 3.3411
SHISA3 shisa family member 3 3.3411
TMEM215 transmembrane protein 215 3.3411
RTN4RL1 reticulon 4 receptor-like 1 3.3411
PADI1 peptidyl arginine deiminase, type I 3.3411
GREM1 gremlin 1, DAN family BMP antagonist 3.3411
SNTN sentan, cilia apical structure protein 3.3411
ACAN aggrecan 3.3411
ATP6V0D2 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 3.3411
NEUROD2 neuronal differentiation 2 3.3411
GHRH growth hormone releasing hormone 3.3411
FGF9 fibroblast growth factor 9 3.3411
MC5R melanocortin 5 receptor 3.3411
TWIST1 twist family bHLH transcription factor 1 3.3411
OR5A2 olfactory receptor, family 5, subfamily A, member 2 3.3411
ABCA13 ATP-binding cassette, sub-family A (ABC1), member 13 3.3411
LRRC38 leucine rich repeat containing 38 3.3411
NLRP1 NLR family, pyrin domain containing 1 3.3411
RERGL RERG/RAS-like 3.3411
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 3.21225
CRLF2 cytokine receptor-like factor 2 3.21225
FAM13A family with sequence similarity 13, member A 3.20537
TIMP2 TIMP metallopeptidase inhibitor 2 3.15424
PHKG2 phosphorylase kinase, gamma 2 (testis) 3.09862
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 3.08179
FNIP2 folliculin interacting protein 2 2.78624
LRFN3 leucine rich repeat and fibronectin type III domain containing 3 2.77691
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 2.69962
GMEB1 glucocorticoid modulatory element binding protein 1 2.62886
LPGAT1 lysophosphatidylglycerol acyltransferase 1 2.61405
C4ORF51 chromosome 4 open reading frame 51 2.60445
ZFP37 ZFP37 zinc finger protein 2.60445
TMEM123 transmembrane protein 123 2.59526
RBP5 retinol binding protein 5, cellular 2.52006
EME2 essential meiotic structure-specific endonuclease subunit 2 2.52006
SF3B2 splicing factor 3b, subunit 2, 145kDa 2.51043
GRK5 G protein-coupled receptor kinase 5 2.50711
ELAC1 elaC ribonuclease Z 1 2.50711
ITPK1 inositol-tetrakisphosphate 1-kinase 2.49432
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 2.48489
OFD1 oral-facial-digital syndrome 1 2.46244
YPEL5 yippee-like 5 (Drosophila) 2.43843
ZGRF1 zinc finger, GRF-type containing 1 2.42777
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa 2.40904
NDFIP2 Nedd4 family interacting protein 2 2.37809
WWC3 WWC family member 3 2.364
EMC7 ER membrane protein complex subunit 7 2.36253
VEZT vezatin, adherens junctions transmembrane protein 2.35145
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit 2.34657
ZNF396 zinc finger protein 396 2.34044
NPC2 Niemann-Pick disease, type C2 2.33596
ZBTB18 zinc finger and BTB domain containing 18 2.32697
ESRRG estrogen-related receptor gamma 2.32685
SLC4A5 solute carrier family 4 (sodium bicarbonate cotransporter), member 5 2.31751
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 2.31464
DGAT2 diacylglycerol O-acyltransferase 2 2.31464
CA3 carbonic anhydrase III 2.31464
TP53TG5 TP53 target 5 2.31464
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 2.27337
TRABD TraB domain containing 2.26691
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 2.23862
EFR3A EFR3 homolog A (S. cerevisiae) 2.23799
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 2.22821
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 2.21634
SPATA18 spermatogenesis associated 18 2.20135
PEX12 peroxisomal biogenesis factor 12 2.20135
RYR3 ryanodine receptor 3 2.17841
TSEN54 TSEN54 tRNA splicing endonuclease subunit 2.13184
COA8 cytochrome c oxidase assembly factor 8 2.13084
H3C12 H3 clustered histone 12 2.12502
CPLANE1 ciliogenesis and planar polarity effector complex subunit 1 2.12502
ARSK arylsulfatase family, member K 2.10702
FOXN3 forkhead box N3 2.10244
RAP1GAP RAP1 GTPase activating protein 2.10189
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 2.10125
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1 2.09777
TMEM120A transmembrane protein 120A 2.09298
ADNP activity-dependent neuroprotector homeobox 2.08555
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 2.08261
MIGA2 mitoguardin 2 2.07203
ACTR10 actin-related protein 10 homolog (S. cerevisiae) 2.06006
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3 2.05301
NMU neuromedin U 2.05144
TXNDC11 thioredoxin domain containing 11 2.05142
WDR49 WD repeat domain 49 2.04128
M1AP meiosis 1 associated protein 2.03496
ANKRD23 ankyrin repeat domain 23 2.03244
ANXA6 annexin A6 2.01651

decreased expression

Symbol Name Standardized Value
CAV2 caveolin 2 -3.3411
PI15 peptidase inhibitor 15 -3.3411
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 -3.3411
EYA4 EYA transcriptional coactivator and phosphatase 4 -3.3411
ZNF232 zinc finger protein 232 -3.3411
LYPD1 LY6/PLAUR domain containing 1 -3.3411
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -3.3411
RECQL4 RecQ protein-like 4 -3.3411
FAAP100 FA core complex associated protein 100 -3.3411
NDNF neuron-derived neurotrophic factor -3.3411
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) -3.3411
MYT1L myelin transcription factor 1-like -3.3411
VWA5B1 von Willebrand factor A domain containing 5B1 -3.3411
SIX1 SIX homeobox 1 -3.20537
TP73 tumor protein p73 -3.20537
IGFBP7 insulin-like growth factor binding protein 7 -3.20537
MRPL53 mitochondrial ribosomal protein L53 -3.20537
OLFM3 olfactomedin 3 -3.20537
TDRD6 tudor domain containing 6 -3.20537
TRAM1L1 translocation associated membrane protein 1-like 1 -3.20537
VSTM2A V-set and transmembrane domain containing 2A -3.20537
PLA2G10 phospholipase A2, group X -3.20537
NLRP7 NLR family, pyrin domain containing 7 -3.20537
RAD21L1 RAD21-like 1 (S. pombe) -3.20537
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 -3.20537
ZDHHC11B zinc finger, DHHC-type containing 11B -3.20537
IFT70B intraflagellar transport 70B -3.20537
SPAAR small regulatory polypeptide of amino acid response -3.20537
RNF227 ring finger protein 227 -3.20537
CDH26 cadherin 26 -3.20537
CAPN3 calpain 3, (p94) -3.20537
ZNF221 zinc finger protein 221 -3.20537
COX8C cytochrome c oxidase subunit VIIIC -3.20537
PLEKHD1 pleckstrin homology domain containing, family D (with coiled-coil domains) member 1 -3.20537
AMBP alpha-1-microglobulin/bikunin precursor -3.20537
TAC1 tachykinin, precursor 1 -3.20537
TSGA10IP testis specific, 10 interacting protein -3.20537
FAM43B family with sequence similarity 43, member B -3.20537
CSRNP1 cysteine-serine-rich nuclear protein 1 -3.20537
KLK8 kallikrein-related peptidase 8 -3.20537
EEF1AKMT2 EEF1A lysine methyltransferase 2 -3.18444
LEMD2 LEM domain containing 2 -3.12298
VEGFA vascular endothelial growth factor A -3.09475
KCNIP2 Kv channel interacting protein 2 -3.01057
CFAP46 cilia and flagella associated protein 46 -3.01057
MYO5B myosin VB -2.94422
CA2 carbonic anhydrase II -2.91416
IQSEC3 IQ motif and Sec7 domain 3 -2.91416
GPSM3 G-protein signaling modulator 3 -2.84286
NAA30 N(alpha)-acetyltransferase 30, NatC catalytic subunit -2.72971
BTBD18 BTB (POZ) domain containing 18 -2.71742
MTHFSD methenyltetrahydrofolate synthetase domain containing -2.71742
TLCD2 TLC domain containing 2 -2.70599
PBX1 pre-B-cell leukemia homeobox 1 -2.69249
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1 -2.64384
IL12RB2 interleukin 12 receptor, beta 2 -2.615
CRELD2 cysteine-rich with EGF-like domains 2 -2.60445
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 -2.58329
KBTBD12 kelch repeat and BTB (POZ) domain containing 12 -2.57837
ANKRD18A ankyrin repeat domain 18A -2.57837
SH3RF3 SH3 domain containing ring finger 3 -2.57837
DKC1 dyskeratosis congenita 1, dyskerin -2.55027
ZNF385C zinc finger protein 385C -2.54336
STIM1 stromal interaction molecule 1 -2.51273
DPP6 dipeptidyl-peptidase 6 -2.49744
C19ORF53 chromosome 19 open reading frame 53 -2.49336
A2M alpha-2-macroglobulin -2.44944
PCLO piccolo presynaptic cytomatrix protein -2.44779
CCNE1 cyclin E1 -2.43229
SRF serum response factor (c-fos serum response element-binding transcription factor) -2.364
RPP25 ribonuclease P/MRP 25kDa subunit -2.35145
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1 -2.34688
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 -2.34094
BTF3 basic transcription factor 3 -2.34094
ADORA2A adenosine A2a receptor -2.33514
CPN1 carboxypeptidase N, polypeptide 1 -2.31464
SLC33A2 solute carrier family 33 member 2 -2.31464
TSSK3 testis-specific serine kinase 3 -2.31464
LHX1 LIM homeobox 1 -2.31464
TMED9 transmembrane emp24 protein transport domain containing 9 -2.29613
IFI30 interferon, gamma-inducible protein 30 -2.26677
MED30 mediator complex subunit 30 -2.26677
SRRM4 serine/arginine repetitive matrix 4 -2.24495
SPSB2 splA/ryanodine receptor domain and SOCS box containing 2 -2.23862
TUB tubby bipartite transcription factor -2.21925
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha -2.21287
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3 -2.19126
ANKRD7 ankyrin repeat domain 7 -2.18003
FES FES proto-oncogene, tyrosine kinase -2.18003
LAMC3 laminin, gamma 3 -2.17443
EHD3 EH-domain containing 3 -2.17133
TMSB4X thymosin beta 4, X-linked -2.15445
NOB1 NIN1/RPN12 binding protein 1 homolog (S. cerevisiae) -2.14086
DIPK1B divergent protein kinase domain 1B -2.13731
ASXL1 additional sex combs like transcriptional regulator 1 -2.12502
BTD biotinidase -2.11823
NFYC nuclear transcription factor Y, gamma -2.11802
GRIK2 glutamate receptor, ionotropic, kainate 2 -2.11375
ZNF658 zinc finger protein 658 -2.10244
GPATCH11 G patch domain containing 11 -2.10244
CILK1 ciliogenesis associated kinase 1 -2.09787
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -2.0971
WDR35 WD repeat domain 35 -2.08555
RNGTT RNA guanylyltransferase and 5'-phosphatase -2.08555
MAEA macrophage erythroblast attacher -2.08261
FHIP2A FHF complex subunit HOOK interacting protein 2A -2.08261
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 -2.06817
MIEN1 migration and invasion enhancer 1 -2.06817
RCC2 regulator of chromosome condensation 2 -2.05586
TICRR TOPBP1-interacting checkpoint and replication regulator -2.05301
RBBP5 retinoblastoma binding protein 5 -2.04611
TFB1M transcription factor B1, mitochondrial -2.04473
PLD5 phospholipase D family, member 5 -2.04146
PPP1R8 protein phosphatase 1, regulatory subunit 8 -2.0382
FANK1 fibronectin type III and ankyrin repeat domains 1 -2.03189
SMCO2 single-pass membrane protein with coiled-coil domains 2 -2.03189
ITGB1BP2 integrin beta 1 binding protein (melusin) 2 -2.03189
INSL3 insulin-like 3 (Leydig cell) -2.03189
ZNF287 zinc finger protein 287 -2.03189
USP2 ubiquitin specific peptidase 2 -2.03189
CD79B CD79b molecule, immunoglobulin-associated beta -2.03189
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase -2.02174
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -2.00266