RNF123 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description ring finger protein 123|The protein encoded by this gene contains a C-terminal RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions, and an N-terminal SPRY domain. This protein displays E3 ubiquitin ligase activity toward the cyclin-dependent kinase inhibitor 1B which is also known as p27 or KIP1. [provided by RefSeq, Feb 2012] (NCBI Entrez Gene Database, 63891)
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Genes

346 genes differentially expressed following the RNF123 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
GJA9 gap junction protein, alpha 9, 59kDa 2.485
NANOS2 nanos homolog 2 (Drosophila) 2.485
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy 2.485
NXPH4 neurexophilin 4 2.485
BTK Bruton agammaglobulinemia tyrosine kinase 2.485
ZNF669 zinc finger protein 669 2.485
PDYN prodynorphin 2.485
PKP1 plakophilin 1 2.485
CLEC19A C-type lectin domain family 19, member A 2.485
TMEM191C transmembrane protein 191C 2.485
SHC2 SHC (Src homology 2 domain containing) transforming protein 2 2.485
CSMD3 CUB and Sushi multiple domains 3 2.485
CABP4 calcium binding protein 4 2.485
SLC46A2 solute carrier family 46, member 2 2.485
GJA5 gap junction protein, alpha 5, 40kDa 2.485
CCDC116 coiled-coil domain containing 116 2.485
HLX H2.0-like homeobox 2.485
CD5 CD5 molecule 2.485
INHBC inhibin, beta C 2.485
CD93 CD93 molecule 2.485
SELPLG selectin P ligand 2.485
RASL10A RAS-like, family 10, member A 2.485
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 2.485
ARID3C AT rich interactive domain 3C (BRIGHT-like) 2.485
PARP3 poly (ADP-ribose) polymerase family, member 3 2.485
FETUB fetuin B 2.485
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 2.485
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 2.485
FAM216B family with sequence similarity 216, member B 2.485
BHMT2 betaine--homocysteine S-methyltransferase 2 2.485
ATOH7 atonal homolog 7 (Drosophila) 2.485
AVP arginine vasopressin 2.485
BMP3 bone morphogenetic protein 3 2.485
TMC8 transmembrane channel-like 8 2.485
ETV2 ets variant 2 2.485
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal) 2.485
MZF1 myeloid zinc finger 1 2.485
EPHB3 EPH receptor B3 2.485
C8ORF74 chromosome 8 open reading frame 74 2.485
PRSS36 protease, serine, 36 2.485
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1 2.485
PECAM1 platelet/endothelial cell adhesion molecule 1 2.485
TRIM74 tripartite motif containing 74 2.485
PTGFR prostaglandin F receptor (FP) 2.485
DRP2 dystrophin related protein 2 2.485
PTGER4 prostaglandin E receptor 4 (subtype EP4) 2.485
GNAT3 guanine nucleotide binding protein, alpha transducing 3 2.485
ARRDC5 arrestin domain containing 5 2.485
TTLL9 tubulin tyrosine ligase-like family member 9 2.485
TTLL2 tubulin tyrosine ligase-like family member 2 2.485
MROH6 maestro heat-like repeat family member 6 2.485
CCDC87 coiled-coil domain containing 87 2.485
MAMSTR MEF2 activating motif and SAP domain containing transcriptional regulator 2.485
CSP2 CS pseudogene 2 2.485
POM121L2 POM121 transmembrane nucleoporin-like 2 2.485
FMO2 flavin containing monooxygenase 2 (non-functional) 2.485
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 2.485
TREX2 three prime repair exonuclease 2 2.485
GRAP GRB2-related adaptor protein 2.485
OR52E5 olfactory receptor, family 52, subfamily E, member 5 2.485
GPR37L1 G protein-coupled receptor 37 like 1 2.485
LY6K lymphocyte antigen 6 complex, locus K 2.485
OSTN osteocrin 2.485
PRDM7 PR domain containing 7 2.485
SYT15 synaptotagmin XV 2.485
SPI1 Spi-1 proto-oncogene 2.485
MGAM maltase-glucoamylase 2.485
CIMAP1B ciliary microtubule associated protein 1B 2.485
LOC124902436 talanin 2.485
TMA7B translation machinery associated 7 homolog B 2.485
SMIM31 small integral membrane protein 31 2.485
CCDC197 coiled-coil domain containing 197 2.485
CFAP206 cilia and flagella associated protein 206 2.485
ITPRID1 ITPR interacting domain containing 1 2.485
GK3 glycerol kinase 3 2.485
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 2.485
SAPCD1 suppressor APC domain containing 1 2.485
AVPR1A arginine vasopressin receptor 1A 2.485
OR10AG1 olfactory receptor, family 10, subfamily AG, member 1 2.485
FGFBP2 fibroblast growth factor binding protein 2 2.485
GOLGA6L4 golgin A6 family-like 4 2.485
AXDND1 axonemal dynein light chain domain containing 1 2.485
FAM43B family with sequence similarity 43, member B 2.485
IRF8 interferon regulatory factor 8 2.485
APC2 adenomatosis polyposis coli 2 2.485
PRB4 proline-rich protein BstNI subfamily 4 2.485
SLC35D3 solute carrier family 35, member D3 2.485
TNS1-AS1 TNS1 antisense RNA 1 2.485
LIPJ lipase, family member J 2.485
LBHD1 LBH domain containing 1 2.485
SLC22A16 solute carrier family 22 (organic cation/carnitine transporter), member 16 2.485
GOLGA7B golgin A7 family, member B 2.485
IL6 interleukin 6 2.485
TIMD4 T-cell immunoglobulin and mucin domain containing 4 2.485
ARHGAP15 Rho GTPase activating protein 15 2.485
C6 complement component 6 2.485
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D 2.485
MTMR11 myotubularin related protein 11 2.485
SBSN suprabasin 2.485
SLC12A9 solute carrier family 12, member 9 2.485
FAM186A family with sequence similarity 186, member A 2.485
SH3TC1 SH3 domain and tetratricopeptide repeats 1 2.485
MIP major intrinsic protein of lens fiber 2.485
TLR6 toll-like receptor 6 2.485
PDILT protein disulfide isomerase-like, testis expressed 2.485
RNASE6 ribonuclease, RNase A family, k6 2.485
KRT15 keratin 15, type I 2.485
GSTT2B glutathione S-transferase theta 2B (gene/pseudogene) 2.485
ETNPPL ethanolamine-phosphate phospho-lyase 2.485
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 2.485
WFDC1 WAP four-disulfide core domain 1 2.485
CD52 CD52 molecule 2.485
PAGE4 P antigen family, member 4 (prostate associated) 2.485
PSKH2 protein serine kinase H2 2.485
ODF1 outer dense fiber of sperm tails 1 2.485
TTC9B tetratricopeptide repeat domain 9B 2.485
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 2.485
ZSCAN1 zinc finger and SCAN domain containing 1 2.485
CLEC4D C-type lectin domain family 4, member D 2.485
LRRC36 leucine rich repeat containing 36 2.485
FOXP2 forkhead box P2 2.485
ZNF366 zinc finger protein 366 2.485
PCDHGB4 protocadherin gamma subfamily B, 4 2.485
LRRC43 leucine rich repeat containing 43 2.485
KCNK4 potassium channel, two pore domain subfamily K, member 4 2.485
SLA2 Src-like-adaptor 2 2.485
PLSCR5 phospholipid scramblase family, member 5 2.485
CER1 cerberus 1, DAN family BMP antagonist 2.485
CNGB3 cyclic nucleotide gated channel beta 3 2.485
FAIM2 Fas apoptotic inhibitory molecule 2 2.485
RASA4 RAS p21 protein activator 4 2.485
ASTN2 astrotactin 2 2.485
ADAM11 ADAM metallopeptidase domain 11 2.485
CCDC78 coiled-coil domain containing 78 2.485
FOXS1 forkhead box S1 2.485
UPK1A uroplakin 1A 2.485
CFP complement factor properdin 2.485
PHOX2A paired-like homeobox 2a 2.485
GSC2 goosecoid homeobox 2 2.485
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 2.485
P2RX6 purinergic receptor P2X, ligand gated ion channel, 6 2.485
EMILIN1 elastin microfibril interfacer 1 2.485
ANKRD20A1 ankyrin repeat domain 20 family, member A1 2.485
PLA1A phospholipase A1 member A 2.485
KLK11 kallikrein-related peptidase 11 2.485
FBXO40 F-box protein 40 2.485
EPHA10 EPH receptor A10 2.485
ZGLP1 zinc finger, GATA-like protein 1 2.485
SIGLEC15 sialic acid binding Ig-like lectin 15 2.485
CTF1 cardiotrophin 1 2.485
ONECUT3 one cut homeobox 3 2.485
FAM81B family with sequence similarity 81, member B 2.485
SHISA3 shisa family member 3 2.485
TGM6 transglutaminase 6 2.485
SYTL4 synaptotagmin-like 4 2.485
TRAM1L1 translocation associated membrane protein 1-like 1 2.485
TICAM1 toll-like receptor adaptor molecule 1 2.485
CD8A CD8a molecule 2.485
TRPM5 transient receptor potential cation channel, subfamily M, member 5 2.485
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 2.485
GLT6D1 glycosyltransferase 6 domain containing 1 2.485
RNF222 ring finger protein 222 2.485
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) 2.485
CDCP2 CUB domain containing protein 2 2.485
HRG histidine-rich glycoprotein 2.485
NPR3 natriuretic peptide receptor 3 2.485
HIGD1C HIG1 hypoxia inducible domain family, member 1C 2.485
PSD4 pleckstrin and Sec7 domain containing 4 2.485
CD34 CD34 molecule 2.485
TMEM52B transmembrane protein 52B 2.485
NPC1L1 NPC1-like 1 2.485
NLRP3 NLR family, pyrin domain containing 3 2.485
OR14A2 olfactory receptor, family 14, subfamily A, member 2 2.485
CHRDL2 chordin-like 2 2.485
MMP3 matrix metallopeptidase 3 2.485
CMPK2 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial 2.485
DCSTAMP dendrocyte expressed seven transmembrane protein 2.485
FAM120C family with sequence similarity 120C 2.485
EPX eosinophil peroxidase 2.485
SP100 SP100 nuclear antigen 2.485
PICK1 protein interacting with PRKCA 1 2.485
ANGEL2 angel homolog 2 (Drosophila) 2.485
GPR50 G protein-coupled receptor 50 2.485
TRIM29 tripartite motif containing 29 2.485
RNF170 ring finger protein 170 2.4667
ADCK1 aarF domain containing kinase 1 2.46094
ZC3H12B zinc finger CCCH-type containing 12B 2.45511
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2 2.42966
GPBP1L1 GC-rich promoter binding protein 1-like 1 2.42562
EFNA5 ephrin-A5 2.41869
PRRT3 proline-rich transmembrane protein 3 2.41575
UFSP1 UFM1-specific peptidase 1 (non-functional) 2.41305
KLF4 Kruppel-like factor 4 (gut) 2.41305
LARP1 La ribonucleoprotein domain family, member 1 2.41305
ZSCAN18 zinc finger and SCAN domain containing 18 2.34206
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14 2.33538
C2CD4D C2 calcium-dependent domain containing 4D 2.33223
C3 complement component 3 2.31773
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 2.31773
ADAP2 ArfGAP with dual PH domains 2 2.31773
RTN4IP1 reticulon 4 interacting protein 1 2.31773
MRPL43 mitochondrial ribosomal protein L43 2.29206
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit 2.27922
TMEM229A transmembrane protein 229A 2.27922
KLHL12 kelch-like family member 12 2.26551
UBE4A ubiquitination factor E4A 2.25089
HSCB HscB mitochondrial iron-sulfur cluster co-chaperone 2.23034
CLHC1 clathrin heavy chain linker domain containing 1 2.22324
RNF214 ring finger protein 214 2.21315
MAPRE2 microtubule-associated protein, RP/EB family, member 2 2.21035
PHYKPL 5-phosphohydroxy-L-lysine phospho-lyase 2.21035
ZNF212 zinc finger protein 212 2.21035
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa 2.21035
IL21R interleukin 21 receptor 2.20697
IFI6 interferon, alpha-inducible protein 6 2.20697
ZFP64 ZFP64 zinc finger protein 2.20465
PHF2 PHD finger protein 2 2.19316
STX4 syntaxin 4 2.19087
MRTFA myocardin related transcription factor A 2.17361
CCDC157 coiled-coil domain containing 157 2.14153
S1PR3 sphingosine-1-phosphate receptor 3 2.12856
RAP1A RAP1A, member of RAS oncogene family 2.09434
TMSB15A thymosin beta 15a 2.09434
SOCS4 suppressor of cytokine signaling 4 2.08974
SEL1L sel-1 suppressor of lin-12-like (C. elegans) 2.0784
SKAP1 src kinase associated phosphoprotein 1 2.0728
MAX MYC associated factor X 2.06351
IMP4 IMP4, U3 small nucleolar ribonucleoprotein 2.06351
ERCC8 excision repair cross-complementation group 8 2.05594
SHISA9 shisa family member 9 2.04375
RAD17 RAD17 homolog (S. pombe) 2.02625

decreased expression

Symbol Name Standardized Value
ACP4 acid phosphatase 4 -2.485
FSCN3 fascin actin-bundling protein 3, testicular -2.485
TCAIM T cell activation inhibitor, mitochondrial -2.485
MYO16 myosin XVI -2.485
PRH1-TAS2R14 PRH1-TAS2R14 readthrough -2.485
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 -2.485
ITIH6 inter-alpha-trypsin inhibitor heavy chain family, member 6 -2.485
RPH3A rabphilin 3A -2.485
SCN8A sodium channel, voltage gated, type VIII alpha subunit -2.485
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 -2.485
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -2.485
CENPK centromere protein K -2.485
PRDX1 peroxiredoxin 1 -2.485
DCST2 DC-STAMP domain containing 2 -2.485
IQSEC3 IQ motif and Sec7 domain 3 -2.485
KLHL22 kelch-like family member 22 -2.485
POU5F2 POU domain class 5, transcription factor 2 -2.485
INPP5J inositol polyphosphate-5-phosphatase J -2.485
RPL34 ribosomal protein L34 -2.485
PTGER3 prostaglandin E receptor 3 (subtype EP3) -2.485
DEFB131B defensin beta 131B -2.485
SPACA9 sperm acrosome associated 9 -2.485
ALPG alkaline phosphatase, germ cell -2.485
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G -2.485
ARMC12 armadillo repeat containing 12 -2.485
SAMD15 sterile alpha motif domain containing 15 -2.485
RERG RAS-like, estrogen-regulated, growth inhibitor -2.485
SCN4A sodium channel, voltage gated, type IV alpha subunit -2.485
EDAR ectodysplasin A receptor -2.485
IRF7 interferon regulatory factor 7 -2.485
PCDHB13 protocadherin beta 13 -2.485
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b -2.485
RPS14 ribosomal protein S14 -2.485
ECT2L epithelial cell transforming 2 like -2.485
HPCAL4 hippocalcin like 4 -2.485
ADRB2 adrenoceptor beta 2, surface -2.485
OR2B6 olfactory receptor, family 2, subfamily B, member 6 -2.485
CHP2 calcineurin-like EF-hand protein 2 -2.485
CMTM2 CKLF-like MARVEL transmembrane domain containing 2 -2.485
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1 -2.485
PLA2G2C phospholipase A2, group IIC -2.485
DXO decapping exoribonuclease -2.485
ANKRD61 ankyrin repeat domain 61 -2.485
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -2.485
GADD45B growth arrest and DNA-damage-inducible, beta -2.485
PCDHA13 protocadherin alpha 13 -2.485
SH2D4B SH2 domain containing 4B -2.485
CLEC18B C-type lectin domain family 18, member B -2.485
PRSS50 protease, serine, 50 -2.485
C10ORF90 chromosome 10 open reading frame 90 -2.485
TRPM1 transient receptor potential cation channel, subfamily M, member 1 -2.485
TMEM200B transmembrane protein 200B -2.485
NDUFA11 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa -2.485
MB myoglobin -2.485
H2AC21 H2A clustered histone 21 -2.46094
CCDC175 coiled-coil domain containing 175 -2.46094
DOK3 docking protein 3 -2.45255
MRPS11 mitochondrial ribosomal protein S11 -2.41788
B3GLCT beta 3-glucosyltransferase -2.40762
LIN9 lin-9 DREAM MuvB core complex component -2.40575
TSFM Ts translation elongation factor, mitochondrial -2.34511
TMEM203 transmembrane protein 203 -2.3417
PPP1R18 protein phosphatase 1, regulatory subunit 18 -2.3417
BCO2 beta-carotene oxygenase 2 -2.34074
MRPL9 mitochondrial ribosomal protein L9 -2.327
DEF6 differentially expressed in FDCP 6 homolog (mouse) -2.32412
SPATS2 spermatogenesis associated, serine-rich 2 -2.31441
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1 -2.30435
DHRS4L2 dehydrogenase/reductase (SDR family) member 4 like 2 -2.2928
NECAP2 NECAP endocytosis associated 2 -2.29251
SURF2 surfeit 2 -2.29206
SIPA1L2 signal-induced proliferation-associated 1 like 2 -2.28972
LYPD6B LY6/PLAUR domain containing 6B -2.28972
STXBP4 syntaxin binding protein 4 -2.25279
UBE2E1 ubiquitin-conjugating enzyme E2E 1 -2.25255
PRR3 proline rich 3 -2.21315
PTPN12 protein tyrosine phosphatase, non-receptor type 12 -2.21315
RPF2 ribosome production factor 2 homolog (S. cerevisiae) -2.21035
CCDC9 coiled-coil domain containing 9 -2.21035
NLRP2 NLR family, pyrin domain containing 2 -2.20697
PKD1L2 polycystic kidney disease 1-like 2 (gene/pseudogene) -2.20609
KCP kielin/chordin-like protein -2.20509
ARHGEF25 Rho guanine nucleotide exchange factor (GEF) 25 -2.20509
RIF1 replication timing regulatory factor 1 -2.19005
CAPN6 calpain 6 -2.18239
DNALI1 dynein, axonemal, light intermediate chain 1 -2.17521
GUF1 GUF1 GTPase homolog (S. cerevisiae) -2.16541
CRAT carnitine O-acetyltransferase -2.16143
NHLRC2 NHL repeat containing 2 -2.13807
RPL36A ribosomal protein L36a -2.13807
ZNF280B zinc finger protein 280B -2.1368
ZSCAN10 zinc finger and SCAN domain containing 10 -2.12856
ADRA1A adrenoceptor alpha 1A -2.12856
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 -2.12195
FOXO1 forkhead box O1 -2.10859
C12ORF57 chromosome 12 open reading frame 57 -2.10859
ANKRD26 ankyrin repeat domain 26 -2.10859
SSR1 signal sequence receptor, alpha -2.10371
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) -2.0913
GGT7 gamma-glutamyltransferase 7 -2.09061
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) -2.08864
ASF1A anti-silencing function 1A histone chaperone -2.0784
NUP214 nucleoporin 214kDa -2.07839
SMCR8 Smith-Magenis syndrome chromosome region, candidate 8 -2.06982
SUFU suppressor of fused homolog (Drosophila) -2.05069
SLFN5 schlafen family member 5 -2.04375
ADAMTSL4 ADAMTS-like 4 -2.04375
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 -2.04187
KIZ kizuna centrosomal protein -2.03213
ZNF24 zinc finger protein 24 -2.03213
LOC730098 uncharacterized LOC730098 -2.02265
GAR1 GAR1 ribonucleoprotein -2.01742
HIP1R huntingtin interacting protein 1 related -2.01087
TMEM132A transmembrane protein 132A -2.00542
UBQLN2 ubiquilin 2 -2.00542