RNF43 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description ring finger protein 43|The protein encoded by this gene is a RING-type E3 ubiquitin ligase and is predicted to contain a transmembrane domain, a protease-associated domain, an ectodomain, and a cytoplasmic RING domain. This protein is thought to negatively regulate Wnt signaling, and expression of this gene results in an increase in ubiquitination of frizzled receptors, an alteration in their subcellular distribution, resulting in reduced surface levels of these receptors. Mutations in this gene have been reported in multiple tumor cells, including colorectal and endometrial cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2015] (NCBI Entrez Gene Database, 54894)
External Link https://ncbi.nlm.nih.gov/gene/54894
Similar Terms
Downloads & Tools

Genes

499 genes differentially expressed following the RNF43 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.0148111
GLOD4 glyoxalase domain containing 4 0.0132214
NVL nuclear VCP-like 0.0128276
IPO13 importin 13 0.0126641
DEGS1 delta(4)-desaturase, sphingolipid 1 0.0118308
NUPR1 nuclear protein, transcriptional regulator, 1 0.011439
TRIB2 tribbles pseudokinase 2 0.0113999
CA12 carbonic anhydrase XII 0.011323
TMEM158 transmembrane protein 158 (gene/pseudogene) 0.0112068
CCL5 chemokine (C-C motif) ligand 5 0.0110094
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 0.0108708
VEGFA vascular endothelial growth factor A 0.01059
ENO2 enolase 2 (gamma, neuronal) 0.0104899
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 0.0104574
S100A9 S100 calcium binding protein A9 0.0100974
SRGN serglycin 0.00991257
JCHAIN joining chain of multimeric IgA and IgM 0.00959242
VCAM1 vascular cell adhesion molecule 1 0.00958099
PKM pyruvate kinase, muscle 0.00956661
COCH cochlin 0.00920151
P3H2 prolyl 3-hydroxylase 2 0.00919682
REG1A regenerating islet-derived 1 alpha 0.00915285
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 0.00910747
KLK3 kallikrein-related peptidase 3 0.00909044
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 0.009054
CXCL9 chemokine (C-X-C motif) ligand 9 0.00900957
JAG1 jagged 1 0.00896918
SMG7 SMG7 nonsense mediated mRNA decay factor 0.00878859
PFKM phosphofructokinase, muscle 0.00860817
MINK1 misshapen-like kinase 1 0.00847552
FXYD2 FXYD domain containing ion transport regulator 2 0.00841915
PLXNB2 plexin B2 0.00830826
RAPSN receptor-associated protein of the synapse 0.00828714
ZNF580 zinc finger protein 580 0.00824221
LCN2 lipocalin 2 0.00823279
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 0.00817636
EMP3 epithelial membrane protein 3 0.00809961
PHLDA2 pleckstrin homology-like domain, family A, member 2 0.00809147
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 0.00807766
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 0.00793303
PRAME preferentially expressed antigen in melanoma 0.00792148
GRWD1 glutamate-rich WD repeat containing 1 0.00791232
NBL1 neuroblastoma 1, DAN family BMP antagonist 0.007893
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 0.00782494
SLC4A2 solute carrier family 4 (anion exchanger), member 2 0.00781815
FADS1 fatty acid desaturase 1 0.00774174
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 0.00771481
ACP3 acid phosphatase 3 0.00768634
TPSAB1 tryptase alpha/beta 1 0.00767697
NEO1 neogenin 1 0.00766278
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.00766021
MLPH melanophilin 0.00765497
KLK2 kallikrein-related peptidase 2 0.00765031
AGRN agrin 0.0076206
STAT1 signal transducer and activator of transcription 1, 91kDa 0.00761865
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.00760856
PIEZO1 piezo-type mechanosensitive ion channel component 1 0.00759665
DCT dopachrome tautomerase 0.00759369
RXRA retinoid X receptor, alpha 0.00758037
TSPAN4 tetraspanin 4 0.00757913
FASN fatty acid synthase 0.00757877
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 0.00754226
BCL2L1 BCL2-like 1 0.00741761
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 0.00740487
QSOX1 quiescin Q6 sulfhydryl oxidase 1 0.00739266
DHCR24 24-dehydrocholesterol reductase 0.00739038
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.00730307
TM7SF2 transmembrane 7 superfamily member 2 0.00729295
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 0.00724004
SSBP3 single stranded DNA binding protein 3 0.00721605
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 0.00720334
PMM1 phosphomannomutase 1 0.00719941
LTBP1 latent transforming growth factor beta binding protein 1 0.00713216
EREG epiregulin 0.00708021
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.00707524
BCAT2 branched chain amino-acid transaminase 2, mitochondrial 0.00706322
COL6A3 collagen, type VI, alpha 3 0.00705519
SMYD3 SET and MYND domain containing 3 0.00705332
OPN3 opsin 3 0.00704809
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 0.00703912
LGALS2 lectin, galactoside-binding, soluble, 2 0.0070228
PLA1A phospholipase A1 member A 0.00700904
TTC38 tetratricopeptide repeat domain 38 0.00700392
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.00699354
FBXO28 F-box protein 28 0.00698156
WT1 Wilms tumor 1 0.00696367
LONP1 lon peptidase 1, mitochondrial 0.00693924
CCL20 chemokine (C-C motif) ligand 20 0.00689156
KIAA0930 KIAA0930 0.00687629
G6PD glucose-6-phosphate dehydrogenase 0.00685095
SFN stratifin 0.00680757
UBE2L6 ubiquitin-conjugating enzyme E2L 6 0.0067798
CAPN1 calpain 1, (mu/I) large subunit 0.00675682
EPS8 epidermal growth factor receptor pathway substrate 8 0.00673774
EPHB2 EPH receptor B2 0.00672992
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.00672519
EML3 echinoderm microtubule associated protein like 3 0.00672072
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.00671492
RNF40 ring finger protein 40, E3 ubiquitin protein ligase 0.0067125
MMP9 matrix metallopeptidase 9 0.00670449
MED15 mediator complex subunit 15 0.00669568
CXCL11 chemokine (C-X-C motif) ligand 11 0.00668443
FXYD3 FXYD domain containing ion transport regulator 3 0.00664858
CST6 cystatin E/M 0.00663733
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.0066355
XCL1 chemokine (C motif) ligand 1 0.00663116
TGFB1 transforming growth factor, beta 1 0.00661381
SMS spermine synthase 0.00660685
MEIS2 Meis homeobox 2 0.00660363
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 0.00660028
DYNLT1 dynein, light chain, Tctex-type 1 0.00659007
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G 0.00658889
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 0.00658069
CNN3 calponin 3, acidic 0.00657363
NADK NAD kinase 0.00655813
PMEL premelanosome protein 0.00655441
TTLL12 tubulin tyrosine ligase-like family member 12 0.0065491
GLS glutaminase 0.00654155
GJA1 gap junction protein, alpha 1, 43kDa 0.00652572
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 0.00650861
RNF19B ring finger protein 19B 0.00647607
GTPBP1 GTP binding protein 1 0.00646395
NARF nuclear prelamin A recognition factor 0.00642898
BCHE butyrylcholinesterase 0.0064209
NPY neuropeptide Y 0.00641466
GRB7 growth factor receptor-bound protein 7 0.00641042
SREBF2 sterol regulatory element binding transcription factor 2 0.00641007
MIOS missing oocyte, meiosis regulator, homolog (Drosophila) 0.00640833
DCXR dicarbonyl/L-xylulose reductase 0.00639914
FAM193B family with sequence similarity 193, member B 0.00639393
DPYD dihydropyrimidine dehydrogenase 0.00637594
CD38 CD38 molecule 0.00637576
S100A7 S100 calcium binding protein A7 0.00637237
TOX3 TOX high mobility group box family member 3 0.00636886
DGS2 DiGeorge syndrome/velocardiofacial syndrome complex 2 0.00635387
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 0.0063264
PKN1 protein kinase N1 0.00632134
NXN nucleoredoxin 0.00631446
PPDPF pancreatic progenitor cell differentiation and proliferation factor 0.00627604
CSTA cystatin A (stefin A) 0.0062594
PYGB phosphorylase, glycogen; brain 0.00624891
ACTL6A actin-like 6A 0.00623784
PXN paxillin 0.0062332
IL7R interleukin 7 receptor 0.00623155
MRM3 mitochondrial rRNA methyltransferase 3 0.0062275
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 0.0061851
CXCL13 chemokine (C-X-C motif) ligand 13 0.00617932
NOTCH2 notch 2 0.00617582
ANXA4 annexin A4 0.00615861
ZBTB18 zinc finger and BTB domain containing 18 0.00613307
USP48 ubiquitin specific peptidase 48 0.00612757
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 0.00612412
DENND4B DENN/MADD domain containing 4B 0.00612308
MT1G metallothionein 1G 0.00611978
HPCAL1 hippocalcin-like 1 0.00611901
AARS1 alanyl-tRNA synthetase 1 0.00611565
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 0.00610945
GDF15 growth differentiation factor 15 0.00610269
COLEC12 collectin sub-family member 12 0.00609545
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.0060948
CXCL10 chemokine (C-X-C motif) ligand 10 0.00608084
SPON2 spondin 2, extracellular matrix protein 0.00603902
ADAM9 ADAM metallopeptidase domain 9 0.00602973
PDGFC platelet derived growth factor C 0.00602667
LTBP2 latent transforming growth factor beta binding protein 2 0.00601359
PNPLA6 patatin-like phospholipase domain containing 6 0.00601043
FBLN1 fibulin 1 0.00599442
ISG15 ISG15 ubiquitin-like modifier 0.00598439
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11 0.00598234
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa 0.00596826
ZMIZ2 zinc finger, MIZ-type containing 2 0.00596462
DDAH1 dimethylarginine dimethylaminohydrolase 1 0.00592821
ADARB1 adenosine deaminase, RNA-specific, B1 0.00592421
HOXC10 homeobox C10 0.00592233
SCO2 SCO2 cytochrome c oxidase assembly protein 0.00592102
ODC1 ornithine decarboxylase 1 0.00591995
BTBD2 BTB (POZ) domain containing 2 0.00591987
BASP1 brain abundant, membrane attached signal protein 1 0.00590915
EPHB6 EPH receptor B6 0.00590365
UROD uroporphyrinogen decarboxylase 0.00588711
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 0.00587637
MUC1 mucin 1, cell surface associated 0.00586784
YARS1 tyrosyl-tRNA synthetase 1 0.00585344
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 0.00581977
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 0.00580474
HBZ hemoglobin, zeta 0.00580378
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 0.00579936
MAZ MYC-associated zinc finger protein (purine-binding transcription factor) 0.0057884
TYK2 tyrosine kinase 2 0.00578116
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2 0.00577752
PMP22 peripheral myelin protein 22 0.00577299
CHMP4A charged multivesicular body protein 4A 0.00576962
RANGAP1 Ran GTPase activating protein 1 0.00575891
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 0.00574112
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.00573824
GARS1 glycyl-tRNA synthetase 1 0.00573099
HDAC9 histone deacetylase 9 0.00573055
RSAD1 radical S-adenosyl methionine domain containing 1 0.00572458
ISYNA1 inositol-3-phosphate synthase 1 0.00570972
GMPR guanosine monophosphate reductase 0.00570671
REG1B regenerating islet-derived 1 beta 0.00570223
CABIN1 calcineurin binding protein 1 0.00569504
ACADVL acyl-CoA dehydrogenase, very long chain 0.00569037
EXOSC4 exosome component 4 0.00568582
IGFBP5 insulin-like growth factor binding protein 5 0.00568092
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2 0.00567202
INTS1 integrator complex subunit 1 0.00566486
PEX6 peroxisomal biogenesis factor 6 0.00565415
WDR13 WD repeat domain 13 0.00563584
ANAPC2 anaphase promoting complex subunit 2 0.00563316
PRF1 perforin 1 (pore forming protein) 0.00561802
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 0.00560336
NIBAN1 niban apoptosis regulator 1 0.00559508
C10ORF10 chromosome 10 open reading frame 10 0.00558853
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 0.00558713
CTNND1 catenin (cadherin-associated protein), delta 1 0.0055855
TGM2 transglutaminase 2 0.0055666
NCDN neurochondrin 0.0055503
TLN1 talin 1 0.00554853
RNF43 ring finger protein 43 0.00554737
EFHD2 EF-hand domain family, member D2 0.00554232
MMP11 matrix metallopeptidase 11 0.00554225
PI3 peptidase inhibitor 3, skin-derived 0.00553162
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 0.00552913
CD46 CD46 molecule, complement regulatory protein 0.00552653
MAGEA3 melanoma antigen family A3 0.0055224
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae) 0.00551264
DPP4 dipeptidyl-peptidase 4 0.00550819
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 0.00550755
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 0.00550635
TMC5 transmembrane channel-like 5 0.00550338
AP2S1 adaptor-related protein complex 2, sigma 1 subunit 0.00550143
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) 0.00550089
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 0.00548483
S100A8 S100 calcium binding protein A8 0.00547586
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.00547197
TNC tenascin C 0.00546984
SLC35F2 solute carrier family 35, member F2 0.0054615
XAF1 XIAP associated factor 1 0.00545393
RGS20 regulator of G-protein signaling 20 0.00545069
ATXN10 ataxin 10 0.00544838
FAM3C family with sequence similarity 3, member C 0.00543251
POU2AF1 POU class 2 associating factor 1 0.00543208
DGKZ diacylglycerol kinase, zeta 0.00541874
NDRG1 N-myc downstream regulated 1 0.00541482
SH3BGRL SH3 domain binding glutamate-rich protein like 0.00541234
GADD45A growth arrest and DNA-damage-inducible, alpha 0.00540766
TMEM106B transmembrane protein 106B 0.00540617
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.00540459

decreased expression

Symbol Name Standardized Value
MAP7 microtubule-associated protein 7 -0.0160017
PROM1 prominin 1 -0.0159717
PUF60 poly-U binding splicing factor 60KDa -0.0153615
GNAS GNAS complex locus -0.0142441
RGCC regulator of cell cycle -0.0139676
HBB hemoglobin, beta -0.0132604
FABP7 fatty acid binding protein 7, brain -0.0123241
CA2 carbonic anhydrase II -0.0123039
SCGB2A1 secretoglobin, family 2A, member 1 -0.0121634
SCRG1 stimulator of chondrogenesis 1 -0.011986
FABP4 fatty acid binding protein 4, adipocyte -0.0115634
PTK2 protein tyrosine kinase 2 -0.0114038
FBLN5 fibulin 5 -0.0113223
GPM6B glycoprotein M6B -0.0112978
ATF3 activating transcription factor 3 -0.0112374
ABLIM1 actin binding LIM protein 1 -0.0108591
CLU clusterin -0.0107894
CRYAB crystallin, alpha B -0.010781
FGFR1 fibroblast growth factor receptor 1 -0.0107368
ACKR3 atypical chemokine receptor 3 -0.01071
BHLHE41 basic helix-loop-helix family, member e41 -0.0106945
CCN2 cellular communication network factor 2 -0.0106059
CPE carboxypeptidase E -0.00997448
KLF6 Kruppel-like factor 6 -0.00992058
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) -0.0098886
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -0.00988819
FAM107A family with sequence similarity 107, member A -0.00988695
TSPAN13 tetraspanin 13 -0.0097846
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein -0.00975314
ADGRG2 adhesion G protein-coupled receptor G2 -0.00974803
SPON1 spondin 1, extracellular matrix protein -0.00974101
FHL1 four and a half LIM domains 1 -0.00973607
RAB11FIP1 RAB11 family interacting protein 1 (class I) -0.00964463
FZD6 frizzled class receptor 6 -0.00963802
NRCAM neuronal cell adhesion molecule -0.00962197
EGR2 early growth response 2 -0.00947641
CLIC5 chloride intracellular channel 5 -0.00939012
GPC3 glypican 3 -0.00936185
ANXA3 annexin A3 -0.00931345
NEBL nebulette -0.00920844
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa -0.00918962
PLP1 proteolipid protein 1 -0.00918579
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 -0.00913533
ITM2C integral membrane protein 2C -0.00913085
GAB2 GRB2-associated binding protein 2 -0.009071
HSPB8 heat shock 22kDa protein 8 -0.00906758
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.00905989
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -0.00904253
MECOM MDS1 and EVI1 complex locus -0.00893719
DLK1 delta-like 1 homolog (Drosophila) -0.00888845
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -0.00884254
BAALC brain and acute leukemia, cytoplasmic -0.00875743
PEG3 paternally expressed 3 -0.00870643
LMCD1 LIM and cysteine-rich domains 1 -0.00869147
AZIN1 antizyme inhibitor 1 -0.00868034
SEPP1 selenoprotein P, plasma, 1 -0.00866022
CKS2 CDC28 protein kinase regulatory subunit 2 -0.00865215
ACTB actin, beta -0.00863302
MBD1 methyl-CpG binding domain protein 1 -0.00862243
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide -0.00861579
CH25H cholesterol 25-hydroxylase -0.00857805
TENT5A terminal nucleotidyltransferase 5A -0.00850079
EIF5 eukaryotic translation initiation factor 5 -0.00843999
CFAP20 cilia and flagella associated protein 20 -0.00838541
CYBA cytochrome b-245, alpha polypeptide -0.00837383
TM9SF3 transmembrane 9 superfamily member 3 -0.00834203
ANO1 anoctamin 1, calcium activated chloride channel -0.00833919
PLLP plasmolipin -0.00832611
PABPC3 poly(A) binding protein, cytoplasmic 3 -0.00826942
RGS5 regulator of G-protein signaling 5 -0.00825348
RBMS1 RNA binding motif, single stranded interacting protein 1 -0.00824502
REEP1 receptor accessory protein 1 -0.00822635
TPBG trophoblast glycoprotein -0.00820907
CYB5R2 cytochrome b5 reductase 2 -0.00820406
MATN2 matrilin 2 -0.0082023
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 -0.00818894
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 -0.00815845
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -0.00811614
ATG3 autophagy related 3 -0.00811333
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa -0.00808489
S100P S100 calcium binding protein P -0.00808145
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 -0.00804995
ANOS1 anosmin 1 -0.00803311
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 -0.00799636
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 -0.00795357
SYNM synemin, intermediate filament protein -0.00794191
U2AF1 U2 small nuclear RNA auxiliary factor 1 -0.00793692
ESR1 estrogen receptor 1 -0.00792264
PPARG peroxisome proliferator-activated receptor gamma -0.00790584
CADM1 cell adhesion molecule 1 -0.00789634
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.00786101
AQP1 aquaporin 1 (Colton blood group) -0.0078598
EIF5A eukaryotic translation initiation factor 5A -0.00785061
CD200 CD200 molecule -0.00782381
TRAM1 translocation associated membrane protein 1 -0.00779382
SRSF5 serine/arginine-rich splicing factor 5 -0.00778483
NLGN4X neuroligin 4, X-linked -0.00777713
SOX17 SRY (sex determining region Y)-box 17 -0.0077663
ASRGL1 asparaginase like 1 -0.00773814
PBX1 pre-B-cell leukemia homeobox 1 -0.00770743
MFAP5 microfibrillar associated protein 5 -0.00767437
TRPS1 trichorhinophalangeal syndrome I -0.00766147
MYO5C myosin VC -0.00760188
TNNC1 troponin C type 1 (slow) -0.00760139
PDZD2 PDZ domain containing 2 -0.00757044
PDE4B phosphodiesterase 4B, cAMP-specific -0.00755987
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) -0.00755664
RET ret proto-oncogene -0.00754812
F3 coagulation factor III (thromboplastin, tissue factor) -0.00752071
ADD3 adducin 3 (gamma) -0.00751278
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) -0.00749734
GSN gelsolin -0.00745693
GMFG glia maturation factor, gamma -0.00745473
KLF4 Kruppel-like factor 4 (gut) -0.00745136
IL6ST interleukin 6 signal transducer -0.00744549
KRT23 keratin 23, type I -0.00739347
HIGD1A HIG1 hypoxia inducible domain family, member 1A -0.00737925
PRNP prion protein -0.00737202
CPVL carboxypeptidase, vitellogenic-like -0.00735497
KLHL41 kelch-like family member 41 -0.00734608
EPB41L3 erythrocyte membrane protein band 4.1-like 3 -0.00731981
SCAMP1 secretory carrier membrane protein 1 -0.00726108
C8ORF4 chromosome 8 open reading frame 4 -0.00723635
LXN latexin -0.0072354
EXOC5 exocyst complex component 5 -0.0072308
SPIN1 spindlin 1 -0.00722694
TMEM100 transmembrane protein 100 -0.00722304
EDN3 endothelin 3 -0.00718153
BEX4 brain expressed, X-linked 4 -0.00716426
ESRP1 epithelial splicing regulatory protein 1 -0.00714997
IGF1 insulin-like growth factor 1 (somatomedin C) -0.0071484
COL14A1 collagen, type XIV, alpha 1 -0.00713907
KLF5 Kruppel-like factor 5 (intestinal) -0.00708903
CHEK2 checkpoint kinase 2 -0.00705153
BCAS1 breast carcinoma amplified sequence 1 -0.0070165
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -0.00701
INSR insulin receptor -0.00700851
WIPI1 WD repeat domain, phosphoinositide interacting 1 -0.00695262
HHEX hematopoietically expressed homeobox -0.00694559
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 -0.00693942
CHMP1B charged multivesicular body protein 1B -0.00693158
S100B S100 calcium binding protein B -0.00692577
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 -0.0069179
FABP5 fatty acid binding protein 5 (psoriasis-associated) -0.00690796
MCL1 myeloid cell leukemia 1 -0.00690719
TPRKB TP53RK binding protein -0.00690509
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 -0.00690075
CD99 CD99 molecule -0.00686353
ELF1 E74-like factor 1 (ets domain transcription factor) -0.00684531
GLUL glutamate-ammonia ligase -0.00684116
PTBP3 polypyrimidine tract binding protein 3 -0.00683606
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -0.00682157
OXTR oxytocin receptor -0.00680276
PPA1 pyrophosphatase (inorganic) 1 -0.00679341
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -0.00679217
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) -0.00676086
CTTN cortactin -0.00675598
ADAM28 ADAM metallopeptidase domain 28 -0.00674725
YIPF5 Yip1 domain family, member 5 -0.00671801
CARMIL1 capping protein regulator and myosin 1 linker 1 -0.00670671
ANXA1 annexin A1 -0.00670453
NOLC1 nucleolar and coiled-body phosphoprotein 1 -0.00670407
TMEM47 transmembrane protein 47 -0.00669804
ATP5MG ATP synthase membrane subunit g -0.00669009
PADI2 peptidyl arginine deiminase, type II -0.00668641
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 -0.00668177
FGF13 fibroblast growth factor 13 -0.00666738
PPP2R2B protein phosphatase 2, regulatory subunit B, beta -0.00666098
GRAMD2B GRAM domain containing 2B -0.00664155
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 -0.00662417
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A -0.00661615
NKX2-2 NK2 homeobox 2 -0.00661496
TPD52 tumor protein D52 -0.00660884
LMO2 LIM domain only 2 (rhombotin-like 1) -0.00660782
ACTA1 actin, alpha 1, skeletal muscle -0.00660224
NFIB nuclear factor I/B -0.00658054
COL9A3 collagen, type IX, alpha 3 -0.00657601
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 -0.00655404
DMD dystrophin -0.00654578
FCGBP Fc fragment of IgG binding protein -0.00654072
ASCL1 achaete-scute family bHLH transcription factor 1 -0.00653993
TXN thioredoxin -0.00652477
DCHS1 dachsous cadherin-related 1 -0.00652214
TMEM243 transmembrane protein 243, mitochondrial -0.00651288
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 -0.00646914
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide -0.00645081
SPRR3 small proline-rich protein 3 -0.00643668
CCNG1 cyclin G1 -0.00643055
FKBP5 FK506 binding protein 5 -0.00642819
CBFB core-binding factor, beta subunit -0.00640993
PPIF peptidylprolyl isomerase F -0.00640558
SOWAHC sosondowah ankyrin repeat domain family member C -0.00640359
MYBPC1 myosin binding protein C, slow type -0.00640288
MRPL42 mitochondrial ribosomal protein L42 -0.00638192
CALCRL calcitonin receptor-like -0.00634534
ITGA6 integrin, alpha 6 -0.0063351
CLDN10 claudin 10 -0.00632768
C1ORF56 chromosome 1 open reading frame 56 -0.00632258
PCSK1 proprotein convertase subtilisin/kexin type 1 -0.00628772
PELI1 pellino E3 ubiquitin protein ligase 1 -0.00628185
RCAN1 regulator of calcineurin 1 -0.00628114
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 -0.00627757
PMP2 peripheral myelin protein 2 -0.00627036
CRK v-crk avian sarcoma virus CT10 oncogene homolog -0.00626682
ZNF706 zinc finger protein 706 -0.00622374
HACD3 3-hydroxyacyl-CoA dehydratase 3 -0.00622139
SDC2 syndecan 2 -0.00620688
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 -0.00620657
GPRC5B G protein-coupled receptor, class C, group 5, member B -0.00620284
FGF9 fibroblast growth factor 9 -0.00620216
PCYOX1 prenylcysteine oxidase 1 -0.00620185
MRPS30 mitochondrial ribosomal protein S30 -0.00620087
MTUS1 microtubule associated tumor suppressor 1 -0.00620076
KLF10 Kruppel-like factor 10 -0.00619113
PDZK1 PDZ domain containing 1 -0.00618807
SRPX2 sushi-repeat containing protein, X-linked 2 -0.00618644
NT5C2 5'-nucleotidase, cytosolic II -0.00618609
TAC1 tachykinin, precursor 1 -0.00618127
THBS4 thrombospondin 4 -0.0061797
KRCC1 lysine-rich coiled-coil 1 -0.00617347
ENY2 enhancer of yellow 2 homolog (Drosophila) -0.00616064
SH3BGR SH3 domain binding glutamate-rich protein -0.00615355
PTGIS prostaglandin I2 (prostacyclin) synthase -0.00615234
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.00615107
GRIA2 glutamate receptor, ionotropic, AMPA 2 -0.00613485
ABHD17B abhydrolase domain containing 17B -0.00613481
MAPRE2 microtubule-associated protein, RP/EB family, member 2 -0.00613258
CASP2 caspase 2, apoptosis-related cysteine peptidase -0.00613214
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 -0.006117
NPTX2 neuronal pentraxin II -0.00611398
CYC1 cytochrome c-1 -0.00611168
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial -0.00609648
MAN1A1 mannosidase, alpha, class 1A, member 1 -0.00608268
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 -0.0060761
CHMP2B charged multivesicular body protein 2B -0.00607193
TRIM36 tripartite motif containing 36 -0.00606148
RNFT1 ring finger protein, transmembrane 1 -0.00605332
CXADR coxsackie virus and adenovirus receptor -0.00605196
ZNF165 zinc finger protein 165 -0.00604839
CRIP1 cysteine-rich protein 1 (intestinal) -0.00604451
BCAT1 branched chain amino-acid transaminase 1, cytosolic -0.00603627
RASA4 RAS p21 protein activator 4 -0.00602852
AK4 adenylate kinase 4 -0.00602189
CCL14 chemokine (C-C motif) ligand 14 -0.00601713
SLPI secretory leukocyte peptidase inhibitor -0.00601463
MEOX2 mesenchyme homeobox 2 -0.00599954
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 -0.00599689
TMEM70 transmembrane protein 70 -0.0059901
NPIPB3 nuclear pore complex interacting protein family, member B3 -0.00596352
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.00595858