RO-3306 Gene Set

Dataset LINCS KinomeScan Kinase Inhibitor Targets
Category physical interactions
Type small molecule
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Genes

32 kinases inhibited by the RO-3306 small molecule from the KinomeScan Kinase Inhibitor Targets dataset.

Symbol Name Standardized Value
STK17A serine/threonine kinase 17a 1.36211
STK17B serine/threonine kinase 17b 1.35325
CIT citron rho-interacting serine/threonine kinase 1.35325
CLK1 CDC-like kinase 1 1.33582
CLK4 CDC-like kinase 4 1.32726
DMPK dystrophia myotonica-protein kinase 1.29393
BMP2K BMP2 inducible kinase 1.26991
CSNK2A2 casein kinase 2, alpha prime polypeptide 1.26991
CLK3 CDC-like kinase 3 1.26991
FLT3 fms-related tyrosine kinase 3 1.25436
STK33 serine/threonine kinase 33 1.23916
CDK7 cyclin-dependent kinase 7 1.22432
MAPK15 mitogen-activated protein kinase 15 1.20983
CLK2 CDC-like kinase 2 1.14877
PRKX protein kinase, X-linked 1.10576
GAK cyclin G associated kinase 1.08283
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.967615
MYLK myosin light chain kinase 0.944052
IRAK1 interleukin-1 receptor-associated kinase 1 0.940302
AAK1 AP2 associated kinase 1 0.922275
CSNK2A1 casein kinase 2, alpha 1 polypeptide 0.908676
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 0.908676
HIPK4 homeodomain interacting protein kinase 4 0.889549
RIOK1 RIO kinase 1 0.886502
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 0.883492
DAPK3 death-associated protein kinase 3 0.866209
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) 0.860727
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 0.855378
PKN2 protein kinase N2 0.852752
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 0.852752
PIM1 Pim-1 proto-oncogene, serine/threonine kinase 0.852752
CSNK1G3 casein kinase 1, gamma 3 0.850157