| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | roundabout, axon guidance receptor, homolog 1 (Drosophila)|Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants emanating from the midline. The product of this gene is a member of the immunoglobulin gene superfamily and encodes an integral membrane protein that functions in axon guidance and neuronal precursor cell migration. This receptor is activated by SLIT-family proteins, resulting in a repulsive effect on glioma cell guidance in the developing brain. A related gene is located at an adjacent region on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009] (NCBI Entrez Gene Database, 6091) |
| External Link | https://ncbi.nlm.nih.gov/gene/6091 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the ROBO1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PROM1 | prominin 1 | 0.0127426 |
| NID2 | nidogen 2 (osteonidogen) | 0.011945 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0113872 |
| CLEC11A | C-type lectin domain family 11, member A | 0.0109358 |
| MXRA7 | matrix-remodelling associated 7 | 0.0106108 |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) | 0.0103952 |
| SFRP1 | secreted frizzled-related protein 1 | 0.0103299 |
| ANXA6 | annexin A6 | 0.0101702 |
| ABAT | 4-aminobutyrate aminotransferase | 0.0100126 |
| SYNGR3 | synaptogyrin 3 | 0.00997839 |
| DLK1 | delta-like 1 homolog (Drosophila) | 0.00988905 |
| KRT14 | keratin 14, type I | 0.00963155 |
| S100A10 | S100 calcium binding protein A10 | 0.00945157 |
| COL16A1 | collagen, type XVI, alpha 1 | 0.00941642 |
| AREG | amphiregulin | 0.00924792 |
| G0S2 | G0/G1 switch 2 | 0.00922756 |
| POLG2 | polymerase (DNA directed), gamma 2, accessory subunit | 0.00882803 |
| JMJD6 | jumonji domain containing 6 | 0.00873182 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | 0.00871076 |
| HOXC6 | homeobox C6 | 0.00859203 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.00846544 |
| PEG3 | paternally expressed 3 | 0.00844782 |
| DSP | desmoplakin | 0.00843286 |
| INHBA | inhibin, beta A | 0.00841351 |
| PTN | pleiotrophin | 0.00808295 |
| CRYAB | crystallin, alpha B | 0.00805397 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 0.00774263 |
| SCG5 | secretogranin V | 0.0076131 |
| THBS4 | thrombospondin 4 | 0.00749732 |
| TFF1 | trefoil factor 1 | 0.00745249 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.00743056 |
| EFHD2 | EF-hand domain family, member D2 | 0.00715131 |
| KRT15 | keratin 15, type I | 0.00714126 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.00710771 |
| SIRT3 | sirtuin 3 | 0.00708828 |
| ABHD2 | abhydrolase domain containing 2 | 0.00708742 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | 0.00706915 |
| RIN2 | Ras and Rab interactor 2 | 0.00702473 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.0069978 |
| MAGED1 | melanoma antigen family D1 | 0.00697502 |
| MAMLD1 | mastermind-like domain containing 1 | 0.00696416 |
| SFRP4 | secreted frizzled-related protein 4 | 0.00687453 |
| PDE4DIP | phosphodiesterase 4D interacting protein | 0.00682138 |
| CLTB | clathrin, light chain B | 0.00680997 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 0.00678751 |
| STK26 | serine/threonine protein kinase 26 | 0.00676451 |
| KRT5 | keratin 5, type II | 0.00675393 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | 0.00674379 |
| GOLGA8H | golgin A8 family, member H | 0.00668889 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.00668511 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0066745 |
| NPTX2 | neuronal pentraxin II | 0.00667437 |
| GPX3 | glutathione peroxidase 3 | 0.0066369 |
| PEG10 | paternally expressed 10 | 0.00662908 |
| SYNE3 | spectrin repeat containing, nuclear envelope family member 3 | 0.00662762 |
| PNMA8A | PNMA family member 8A | 0.00662438 |
| PUF60 | poly-U binding splicing factor 60KDa | 0.00661302 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | 0.00660519 |
| MMP9 | matrix metallopeptidase 9 | 0.00648771 |
| LAMB1 | laminin, beta 1 | 0.00641521 |
| SIDT2 | SID1 transmembrane family, member 2 | 0.00639688 |
| LAMC2 | laminin, gamma 2 | 0.00636312 |
| XYLT1 | xylosyltransferase I | 0.00634573 |
| APOD | apolipoprotein D | 0.00634494 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.00633845 |
| LCN2 | lipocalin 2 | 0.00628434 |
| PRKCZ | protein kinase C, zeta | 0.00625422 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00622346 |
| LSM7 | LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00619895 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | 0.00619228 |
| VPS4B | vacuolar protein sorting 4 homolog B (S. cerevisiae) | 0.00619067 |
| PLK2 | polo-like kinase 2 | 0.00616713 |
| NPC2 | Niemann-Pick disease, type C2 | 0.0061336 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.00612059 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.00611416 |
| TTC39A | tetratricopeptide repeat domain 39A | 0.00608956 |
| LMNA | lamin A/C | 0.00607774 |
| CDC20 | cell division cycle 20 | 0.00604625 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 | 0.00604524 |
| RABAC1 | Rab acceptor 1 (prenylated) | 0.00602846 |
| S100A11 | S100 calcium binding protein A11 | 0.00602443 |
| MRPL23 | mitochondrial ribosomal protein L23 | 0.00601609 |
| LOXL1 | lysyl oxidase-like 1 | 0.00599854 |
| SRPX | sushi-repeat containing protein, X-linked | 0.00598127 |
| S100A7 | S100 calcium binding protein A7 | 0.00597796 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 0.0059218 |
| MT1X | metallothionein 1X | 0.00592093 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.00591501 |
| CCNA2 | cyclin A2 | 0.00590786 |
| NRIP3 | nuclear receptor interacting protein 3 | 0.00586792 |
| MXD4 | MAX dimerization protein 4 | 0.00584955 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.00584623 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) | 0.00583876 |
| ISLR | immunoglobulin superfamily containing leucine-rich repeat | 0.0058162 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.00581051 |
| EIF3F | eukaryotic translation initiation factor 3, subunit F | 0.00580842 |
| COBL | cordon-bleu WH2 repeat protein | 0.00579195 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | 0.00579148 |
| TYMS | thymidylate synthetase | 0.00575812 |
| ANKRD11 | ankyrin repeat domain 11 | 0.00575733 |
| RBM47 | RNA binding motif protein 47 | 0.00571907 |
| SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) | 0.00569272 |
| NDN | necdin, melanoma antigen (MAGE) family member | 0.00568372 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | 0.00568306 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | 0.00567294 |
| MMP7 | matrix metallopeptidase 7 | 0.00566427 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.00564437 |
| CLDN4 | claudin 4 | 0.00561705 |
| COL6A1 | collagen, type VI, alpha 1 | 0.00559991 |
| TIMM13 | translocase of inner mitochondrial membrane 13 homolog (yeast) | 0.00559186 |
| IGFBP6 | insulin-like growth factor binding protein 6 | 0.00557507 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.00557398 |
| TNC | tenascin C | 0.00556524 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.00555168 |
| INAVA | innate immunity activator | 0.00552175 |
| LOC283683 | uncharacterized LOC283683 | 0.00551689 |
| TSPO | translocator protein (18kDa) | 0.00551228 |
| SOX10 | SRY (sex determining region Y)-box 10 | 0.00549269 |
| EHD1 | EH-domain containing 1 | 0.00549062 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.00547983 |
| COL9A3 | collagen, type IX, alpha 3 | 0.00546645 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.00546518 |
| LY6E | lymphocyte antigen 6 complex, locus E | 0.00545377 |
| RSRP1 | arginine/serine-rich protein 1 | 0.00544821 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.00544417 |
| PENK | proenkephalin | 0.00542284 |
| SLC22A18 | solute carrier family 22, member 18 | 0.00541331 |
| PLSCR3 | phospholipid scramblase 3 | 0.005361 |
| CCN2 | cellular communication network factor 2 | 0.00534999 |
| CRABP1 | cellular retinoic acid binding protein 1 | 0.00534181 |
| COL6A2 | collagen, type VI, alpha 2 | 0.00534059 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.00533576 |
| EPCAM | epithelial cell adhesion molecule | 0.00531298 |
| NR0B1 | nuclear receptor subfamily 0, group B, member 1 | 0.00530838 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00530818 |
| NOTCH2NL | notch 2 N-terminal like | 0.00529788 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0052964 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 | 0.00529501 |
| SLC46A3 | solute carrier family 46, member 3 | 0.0052822 |
| OPN3 | opsin 3 | 0.00527211 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.00526991 |
| BOP1 | block of proliferation 1 | 0.00525832 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.00523354 |
| TAX1BP3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 | 0.00522492 |
| MXRA8 | matrix-remodelling associated 8 | 0.00521873 |
| RORA | RAR-related orphan receptor A | 0.00520588 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.00519164 |
| SOHLH2 | spermatogenesis and oogenesis specific basic helix-loop-helix 2 | 0.00518178 |
| ZDHHC7 | zinc finger, DHHC-type containing 7 | 0.00517769 |
| CD151 | CD151 molecule (Raph blood group) | 0.00516454 |
| MT1F | metallothionein 1F | 0.00515739 |
| LDHB | lactate dehydrogenase B | 0.00511804 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | 0.00510137 |
| RAB40B | RAB40B, member RAS oncogene family | 0.00510052 |
| CYBA | cytochrome b-245, alpha polypeptide | 0.00509038 |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 | 0.00504775 |
| UBXN1 | UBX domain protein 1 | 0.00503233 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.00502058 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | 0.00501535 |
| MGP | matrix Gla protein | 0.00499829 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | 0.00499779 |
| NMB | neuromedin B | 0.00498771 |
| EGR3 | early growth response 3 | 0.00497588 |
| TGFA | transforming growth factor, alpha | 0.00497211 |
| PCNA | proliferating cell nuclear antigen | 0.004964 |
| AMOTL2 | angiomotin like 2 | 0.00496318 |
| KRT23 | keratin 23, type I | 0.00496226 |
| NKX2-2 | NK2 homeobox 2 | 0.0049604 |
| LAT2 | linker for activation of T cells family, member 2 | 0.00495386 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist | 0.00494945 |
| BLNK | B-cell linker | 0.00494544 |
| TFF3 | trefoil factor 3 (intestinal) | 0.00493795 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00493674 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.00493555 |
| PTTG1 | pituitary tumor-transforming 1 | 0.00493398 |
| SEC11A | SEC11 homolog A (S. cerevisiae) | 0.00493229 |
| EFHD1 | EF-hand domain family, member D1 | 0.00491678 |
| MAPK13 | mitogen-activated protein kinase 13 | 0.0049154 |
| SCPEP1 | serine carboxypeptidase 1 | 0.00490882 |
| ARL6IP5 | ADP-ribosylation factor-like 6 interacting protein 5 | 0.00490485 |
| MAP9 | microtubule-associated protein 9 | 0.00490238 |
| TWF2 | twinfilin actin binding protein 2 | 0.00489421 |
| GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 | 0.00488119 |
| SIX1 | SIX homeobox 1 | 0.00487182 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | 0.00486771 |
| COL1A2 | collagen, type I, alpha 2 | 0.00486415 |
| OSR2 | odd-skipped related transciption factor 2 | 0.00486082 |
| MMP1 | matrix metallopeptidase 1 | 0.00485552 |
| GOLGA8A | golgin A8 family, member A | 0.0048523 |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 | 0.00485061 |
| GLS | glutaminase | 0.00483124 |
| PKP1 | plakophilin 1 | 0.0048288 |
| ATP6V0D1 | ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 | 0.00482606 |
| AK1 | adenylate kinase 1 | 0.00482116 |
| SEPTIN9 | septin 9 | 0.00479636 |
| HSPB11 | heat shock protein family B (small), member 11 | 0.0047917 |
| EPS8L2 | EPS8-like 2 | 0.00478496 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0047629 |
| HSPA1A | heat shock 70kDa protein 1A | 0.00474663 |
| THBS2 | thrombospondin 2 | 0.00474481 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.00474314 |
| PLAUR | plasminogen activator, urokinase receptor | 0.00473512 |
| SACS | sacsin molecular chaperone | 0.00472856 |
| KRT7 | keratin 7, type II | 0.00471752 |
| TPBG | trophoblast glycoprotein | 0.00471722 |
| TBCB | tubulin folding cofactor B | 0.00470932 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.00470207 |
| SUSD6 | sushi domain containing 6 | 0.00469984 |
| RPS27L | ribosomal protein S27-like | 0.00468841 |
| PRR7 | proline rich 7 (synaptic) | 0.00468748 |
| SLC52A2 | solute carrier family 52 (riboflavin transporter), member 2 | 0.00468695 |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 | 0.00468054 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.00466982 |
| SPATA20 | spermatogenesis associated 20 | 0.00465211 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | 0.00463975 |
| SMAD7 | SMAD family member 7 | 0.00463533 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | 0.00463466 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | 0.00463457 |
| ELF5 | E74-like factor 5 (ets domain transcription factor) | 0.0046318 |
| PDGFRL | platelet-derived growth factor receptor-like | 0.00462394 |
| CTSH | cathepsin H | 0.00462075 |
| HOPX | HOP homeobox | 0.00461527 |
| CEL | carboxyl ester lipase | 0.00460223 |
| PPIF | peptidylprolyl isomerase F | 0.00460208 |
| CLIC3 | chloride intracellular channel 3 | 0.00459912 |
| BSPRY | B-box and SPRY domain containing | 0.00459748 |
| PDGFC | platelet derived growth factor C | 0.00457751 |
| DSTN | destrin (actin depolymerizing factor) | 0.00457427 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | 0.00454875 |
| MEG3 | maternally expressed 3 (non-protein coding) | 0.00454752 |
| MMP3 | matrix metallopeptidase 3 | 0.0045457 |
| CD37 | CD37 molecule | 0.004538 |
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 | 0.00453398 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.00453127 |
| KDSR | 3-ketodihydrosphingosine reductase | 0.00452625 |
| JMJD1C | jumonji domain containing 1C | 0.00451771 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.00450883 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | 0.00450768 |
| PRPF4 | pre-mRNA processing factor 4 | 0.00449547 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | 0.00449105 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.00448981 |
| PDZK1IP1 | PDZK1 interacting protein 1 | 0.00448969 |
| UBE2S | ubiquitin-conjugating enzyme E2S | 0.00447418 |
| ETNK1 | ethanolamine kinase 1 | 0.00447103 |
| SPON2 | spondin 2, extracellular matrix protein | 0.0044578 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00444966 |
| FAM216A | family with sequence similarity 216, member A | 0.00444906 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.00443293 |
| BIN1 | bridging integrator 1 | 0.00441562 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.00441353 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AQP3 | aquaporin 3 (Gill blood group) | -0.0136641 |
| SNX11 | sorting nexin 11 | -0.0127046 |
| LAMP3 | lysosomal-associated membrane protein 3 | -0.0125144 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -0.0116597 |
| HBB | hemoglobin, beta | -0.0114605 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.0110061 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.0109333 |
| MECOM | MDS1 and EVI1 complex locus | -0.0107612 |
| IFI44L | interferon-induced protein 44-like | -0.010709 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.0106145 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | -0.0103591 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.0102759 |
| CXADR | coxsackie virus and adenovirus receptor | -0.01001 |
| CA2 | carbonic anhydrase II | -0.00998804 |
| IFI44 | interferon-induced protein 44 | -0.00961652 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | -0.00958208 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | -0.00956096 |
| MBD1 | methyl-CpG binding domain protein 1 | -0.00927575 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.00904855 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.00904732 |
| HCRT | hypocretin (orexin) neuropeptide precursor | -0.00900444 |
| C10ORF10 | chromosome 10 open reading frame 10 | -0.00899036 |
| CLU | clusterin | -0.00895677 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.00890244 |
| ABLIM1 | actin binding LIM protein 1 | -0.00858926 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | -0.00845424 |
| TGM2 | transglutaminase 2 | -0.00834947 |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 | -0.00829419 |
| CPA3 | carboxypeptidase A3 (mast cell) | -0.00826017 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | -0.00824507 |
| CPB1 | carboxypeptidase B1 (tissue) | -0.00804872 |
| RGCC | regulator of cell cycle | -0.0079356 |
| PIR | pirin (iron-binding nuclear protein) | -0.00790441 |
| PSAT1 | phosphoserine aminotransferase 1 | -0.00786272 |
| CD93 | CD93 molecule | -0.00784899 |
| SPARCL1 | SPARC-like 1 (hevin) | -0.00777365 |
| CLEC2B | C-type lectin domain family 2, member B | -0.00768219 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.007591 |
| GIMAP4 | GTPase, IMAP family member 4 | -0.00749218 |
| SST | somatostatin | -0.00747683 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00742287 |
| TAL1 | T-cell acute lymphocytic leukemia 1 | -0.00739032 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | -0.00731847 |
| MUC16 | mucin 16, cell surface associated | -0.00726406 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.00716819 |
| GIMAP6 | GTPase, IMAP family member 6 | -0.00714947 |
| HNMT | histamine N-methyltransferase | -0.00710694 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.00705995 |
| BTG3 | BTG family, member 3 | -0.00703869 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.00703014 |
| VWF | von Willebrand factor | -0.00702076 |
| EPHB2 | EPH receptor B2 | -0.00700854 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00699278 |
| MMP10 | matrix metallopeptidase 10 | -0.00697062 |
| PDE2A | phosphodiesterase 2A, cGMP-stimulated | -0.00691111 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.00689897 |
| TSPAN8 | tetraspanin 8 | -0.00687308 |
| TMSB15A | thymosin beta 15a | -0.00686416 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.00685425 |
| ST6GALNAC5 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 | -0.00683281 |
| CPE | carboxypeptidase E | -0.00677068 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | -0.00676796 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | -0.00676424 |
| ZNF395 | zinc finger protein 395 | -0.00676325 |
| EMX2 | empty spiracles homeobox 2 | -0.00674774 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | -0.00674193 |
| RAB21 | RAB21, member RAS oncogene family | -0.00660332 |
| CNN3 | calponin 3, acidic | -0.00659295 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.00656988 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase | -0.0064828 |
| CHEK2 | checkpoint kinase 2 | -0.00646543 |
| C8ORF4 | chromosome 8 open reading frame 4 | -0.00643437 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.00639013 |
| C7 | complement component 7 | -0.00633964 |
| ORC1 | origin recognition complex, subunit 1 | -0.00627899 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | -0.00627465 |
| HSPA4 | heat shock 70kDa protein 4 | -0.00622205 |
| TPM4 | tropomyosin 4 | -0.00618582 |
| GBP1 | guanylate binding protein 1, interferon-inducible | -0.00616899 |
| AGTR1 | angiotensin II receptor, type 1 | -0.00608884 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -0.00606796 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | -0.00603076 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.00602087 |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 | -0.00601137 |
| PLN | phospholamban | -0.0059949 |
| ITGA6 | integrin, alpha 6 | -0.00597443 |
| REG3A | regenerating islet-derived 3 alpha | -0.00594555 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.00594325 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.00591945 |
| MRTFB | myocardin related transcription factor B | -0.00591303 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.00588146 |
| SRGN | serglycin | -0.00587164 |
| SCARB2 | scavenger receptor class B, member 2 | -0.00586212 |
| NTS | neurotensin | -0.00577831 |
| ACKR3 | atypical chemokine receptor 3 | -0.00577134 |
| DPYD | dihydropyrimidine dehydrogenase | -0.00576407 |
| AQP1 | aquaporin 1 (Colton blood group) | -0.0057546 |
| HSD17B6 | hydroxysteroid (17-beta) dehydrogenase 6 | -0.00574985 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.0057433 |
| MSLN | mesothelin | -0.00573925 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | -0.00572939 |
| CPB2 | carboxypeptidase B2 (plasma) | -0.00570725 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | -0.00570593 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.00570417 |
| BTBD3 | BTB (POZ) domain containing 3 | -0.0057015 |
| CNTN1 | contactin 1 | -0.00569199 |
| IL33 | interleukin 33 | -0.00568568 |
| FOXF1 | forkhead box F1 | -0.00564697 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.00562255 |
| MYRF | myelin regulatory factor | -0.00562071 |
| PNOC | prepronociceptin | -0.00560743 |
| HOXB7 | homeobox B7 | -0.00560538 |
| NRN1 | neuritin 1 | -0.00558207 |
| GSTO1 | glutathione S-transferase omega 1 | -0.00558047 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.00557646 |
| DCAF10 | DDB1 and CUL4 associated factor 10 | -0.00555457 |
| GPC3 | glypican 3 | -0.00554589 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.00553223 |
| HP | haptoglobin | -0.00553029 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | -0.00551515 |
| COL4A5 | collagen, type IV, alpha 5 | -0.00548055 |
| HOXD1 | homeobox D1 | -0.00543202 |
| SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F | -0.00540093 |
| KCTD12 | potassium channel tetramerization domain containing 12 | -0.00539343 |
| GLUL | glutamate-ammonia ligase | -0.00539166 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.0053803 |
| TESK1 | testis-specific kinase 1 | -0.00537653 |
| NEBL | nebulette | -0.0053718 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | -0.00536952 |
| CALCRL | calcitonin receptor-like | -0.0053376 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | -0.00532781 |
| SOX13 | SRY (sex determining region Y)-box 13 | -0.00531802 |
| MMRN1 | multimerin 1 | -0.00531572 |
| LUM | lumican | -0.00531329 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | -0.00531206 |
| LYPD1 | LY6/PLAUR domain containing 1 | -0.00530795 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | -0.00530568 |
| TFR2 | transferrin receptor 2 | -0.00530508 |
| PTH2R | parathyroid hormone 2 receptor | -0.00528625 |
| GSTA1 | glutathione S-transferase alpha 1 | -0.00527039 |
| MEIS2 | Meis homeobox 2 | -0.00526712 |
| FCN3 | ficolin (collagen/fibrinogen domain containing) 3 | -0.00525224 |
| FABP6 | fatty acid binding protein 6, ileal | -0.0052442 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.00524092 |
| ATF3 | activating transcription factor 3 | -0.00524031 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | -0.00521925 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.00520997 |
| FLT1 | fms-related tyrosine kinase 1 | -0.00519393 |
| CAND1 | cullin-associated and neddylation-dissociated 1 | -0.00518523 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.00518455 |
| EPAS1 | endothelial PAS domain protein 1 | -0.00517505 |
| DOK5 | docking protein 5 | -0.00517013 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.00516892 |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 | -0.00515899 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.00515607 |
| ALOX5 | arachidonate 5-lipoxygenase | -0.0051435 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) | -0.00514213 |
| OTC | ornithine carbamoyltransferase | -0.0051409 |
| ATF4 | activating transcription factor 4 | -0.00513982 |
| ARAP3 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 | -0.00513507 |
| RHOB | ras homolog family member B | -0.00513336 |
| ANOS1 | anosmin 1 | -0.00513125 |
| BHMT | betaine--homocysteine S-methyltransferase | -0.00510986 |
| COL4A6 | collagen, type IV, alpha 6 | -0.00508229 |
| DAXX | death-domain associated protein | -0.00507393 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | -0.00506771 |
| GCK | glucokinase (hexokinase 4) | -0.0050591 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.00503101 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | -0.00502389 |
| APOC3 | apolipoprotein C-III | -0.0050213 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.00501011 |
| DEFA5 | defensin, alpha 5, Paneth cell-specific | -0.00499612 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | -0.00499303 |
| UXT | ubiquitously-expressed, prefoldin-like chaperone | -0.0049913 |
| DCHS1 | dachsous cadherin-related 1 | -0.00497399 |
| STOM | stomatin | -0.00495185 |
| OIP5 | Opa interacting protein 5 | -0.00493876 |
| PEX2 | peroxisomal biogenesis factor 2 | -0.00493619 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00493326 |
| ADAM28 | ADAM metallopeptidase domain 28 | -0.00491551 |
| ATG5 | autophagy related 5 | -0.00491414 |
| FASN | fatty acid synthase | -0.00489809 |
| PRKD3 | protein kinase D3 | -0.00489742 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.00489277 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.00488763 |
| TRAF5 | TNF receptor-associated factor 5 | -0.00488596 |
| PODXL | podocalyxin-like | -0.0048724 |
| CDH5 | cadherin 5, type 2 (vascular endothelium) | -0.00486963 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.00486871 |
| MARS1 | methionyl-tRNA synthetase 1 | -0.00486152 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.00485832 |
| CCL14 | chemokine (C-C motif) ligand 14 | -0.00485204 |
| ADAR | adenosine deaminase, RNA-specific | -0.00484766 |
| HCP5 | HLA complex P5 (non-protein coding) | -0.00484682 |
| DIPK1A | divergent protein kinase domain 1A | -0.0048363 |
| TRIB3 | tribbles pseudokinase 3 | -0.00482871 |
| PHACTR4 | phosphatase and actin regulator 4 | -0.00482603 |
| CBX1 | chromobox homolog 1 | -0.00481346 |
| RNF38 | ring finger protein 38 | -0.00481304 |
| POGK | pogo transposable element with KRAB domain | -0.0047948 |
| ARG1 | arginase 1 | -0.00479033 |
| PRAME | preferentially expressed antigen in melanoma | -0.00478472 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | -0.00478044 |
| CLC | Charcot-Leyden crystal galectin | -0.00477888 |
| UNC13B | unc-13 homolog B (C. elegans) | -0.00476991 |
| CHN1 | chimerin 1 | -0.00476792 |
| KCNN3 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3 | -0.00476503 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | -0.00475804 |
| TDO2 | tryptophan 2,3-dioxygenase | -0.00474792 |
| AADAC | arylacetamide deacetylase | -0.00474631 |
| DEDD | death effector domain containing | -0.00474364 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.0047358 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.00472682 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) | -0.00472549 |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) | -0.00472238 |
| MID1IP1 | MID1 interacting protein 1 | -0.0047187 |
| TSPAN7 | tetraspanin 7 | -0.00469426 |
| CDC6 | cell division cycle 6 | -0.00469337 |
| NIBAN1 | niban apoptosis regulator 1 | -0.00469159 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.0046848 |
| SOX17 | SRY (sex determining region Y)-box 17 | -0.0046814 |
| AQP4 | aquaporin 4 | -0.00467767 |
| SRSF1 | serine/arginine-rich splicing factor 1 | -0.00467094 |
| IDE | insulin-degrading enzyme | -0.00466346 |
| FANCG | Fanconi anemia, complementation group G | -0.004659 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.00465763 |
| GNE | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase | -0.00465142 |
| ATXN10 | ataxin 10 | -0.0046319 |
| RBX1 | ring-box 1, E3 ubiquitin protein ligase | -0.00462602 |
| ADH1A | alcohol dehydrogenase 1A (class I), alpha polypeptide | -0.00462524 |
| CD1E | CD1e molecule | -0.00461496 |
| NPL | N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) | -0.00460597 |
| MAP3K7CL | MAP3K7 C-terminal like | -0.00460308 |
| ODC1 | ornithine decarboxylase 1 | -0.00458264 |
| FAM107A | family with sequence similarity 107, member A | -0.0045671 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | -0.00456662 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | -0.00456661 |
| GPM6A | glycoprotein M6A | -0.00456278 |
| FKBP4 | FK506 binding protein 4, 59kDa | -0.00455966 |
| AGPS | alkylglycerone phosphate synthase | -0.00455544 |
| CADM1 | cell adhesion molecule 1 | -0.00454711 |
| CLDN10 | claudin 10 | -0.00454697 |
| CLIC5 | chloride intracellular channel 5 | -0.0045464 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 | -0.00453647 |
| SFTPC | surfactant protein C | -0.00453027 |
| NPAS2 | neuronal PAS domain protein 2 | -0.00452782 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | -0.00452758 |
| CHMP5 | charged multivesicular body protein 5 | -0.00451251 |
| CDK14 | cyclin-dependent kinase 14 | -0.00451042 |
| HIST1H2AE | histone cluster 1, H2ae | -0.00450346 |
