ROBO2 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description roundabout, axon guidance receptor, homolog 2 (Drosophila)|The protein encoded by this gene belongs to the ROBO family, part of the immunoglobulin superfamily of proteins that are highly conserved from fly to human. The encoded protein is a transmembrane receptor for the slit homolog 2 protein and functions in axon guidance and cell migration. Mutations in this gene are associated with vesicoureteral reflux, characterized by the backward flow of urine from the bladder into the ureters or the kidney. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014] (NCBI Entrez Gene Database, 6092)
External Link http://www.ncbi.nlm.nih.gov/gene/6092
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Genes

64 interacting proteins for ROBO2 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AMOTL2 angiomotin like 2
ARSB arylsulfatase B
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ATAD3B ATPase family, AAA domain containing 3B
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CEP170 centrosomal protein 170kDa
CPE carboxypeptidase E
CSPP1 centrosome and spindle pole associated protein 1
DOCK7 dedicator of cytokinesis 7
ERBB2IP erbb2 interacting protein
FAM122B family with sequence similarity 122B
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HSPA8 heat shock 70kDa protein 8
IK IK cytokine, down-regulator of HLA II
IKZF2 IKAROS family zinc finger 2 (Helios)
IL4R interleukin 4 receptor
IQCE IQ motif containing E
KCNRG potassium channel regulator
KIF25 kinesin family member 25
KNDC1 kinase non-catalytic C-lobe domain (KIND) containing 1
LECT1 leukocyte cell derived chemotaxin 1
LMNA lamin A/C
LMO7 LIM domain 7
LRPPRC leucine-rich pentatricopeptide repeat containing
MAX MYC associated factor X
MFGE8 milk fat globule-EGF factor 8 protein
MICALL2 MICAL-like 2
MIPEP mitochondrial intermediate peptidase
MLH3 mutL homolog 3
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAV2 neuron navigator 2
NLRX1 NLR family member X1
NR1H2 nuclear receptor subfamily 1, group H, member 2
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRXN3 neurexin 3
OLFM2 olfactomedin 2
PDZD2 PDZ domain containing 2
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B
PRKCDBP protein kinase C, delta binding protein
PTPN14 protein tyrosine phosphatase, non-receptor type 14
PTRF polymerase I and transcript release factor
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RCOR3 REST corepressor 3
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RIMS2 regulating synaptic membrane exocytosis 2
RIN3 Ras and Rab interactor 3
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
SCO2 SCO2 cytochrome c oxidase assembly protein
SDK1 sidekick cell adhesion molecule 1
SEC31B SEC31 homolog B (S. cerevisiae)
SLIT2 slit homolog 2 (Drosophila)
SLIT3 slit homolog 3 (Drosophila)
SPATA31E1 SPATA31 subfamily E, member 1
SPEG SPEG complex locus
SSRP1 structure specific recognition protein 1
TRIM13 tripartite motif containing 13
TTN titin
TUBA4A tubulin, alpha 4a
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBQLN4 ubiquilin 4
XDH xanthine dehydrogenase
XYLT1 xylosyltransferase I
ZCCHC11 zinc finger, CCHC domain containing 11