ROCK2 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description Rho-associated, coiled-coil containing protein kinase 2|The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 9475)
External Link https://ncbi.nlm.nih.gov/gene/9475
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Genes

499 genes differentially expressed following the ROCK2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
EFNB2 ephrin-B2 0.0152595
TPSAB1 tryptase alpha/beta 1 0.0148737
NOTCH2NL notch 2 N-terminal like 0.013603
NBPF10 neuroblastoma breakpoint family, member 10 0.0131091
PILRB paired immunoglobin-like type 2 receptor beta 0.0125014
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) 0.0124811
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.0121893
LPAR2 lysophosphatidic acid receptor 2 0.0120166
SLIT2 slit homolog 2 (Drosophila) 0.0119297
TXLNA taxilin alpha 0.01153
CCND2 cyclin D2 0.0113082
PNN pinin, desmosome associated protein 0.0112056
MFSD10 major facilitator superfamily domain containing 10 0.0111477
CREB1 cAMP responsive element binding protein 1 0.0110559
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0107305
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.0106533
PHACTR2 phosphatase and actin regulator 2 0.0105767
CD320 CD320 molecule 0.0105703
ENC1 ectodermal-neural cortex 1 (with BTB domain) 0.0104736
DYNLL1 dynein, light chain, LC8-type 1 0.0104247
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 0.0104163
SUGP2 SURP and G patch domain containing 2 0.0104043
EML3 echinoderm microtubule associated protein like 3 0.0102484
NSD2 nuclear receptor binding SET domain protein 2 0.0102049
NOTCH2 notch 2 0.0101798
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A 0.0101682
PTK2B protein tyrosine kinase 2 beta 0.0101605
TRIO trio Rho guanine nucleotide exchange factor 0.0101414
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) 0.0100597
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase 0.0100394
ARID1A AT rich interactive domain 1A (SWI-like) 0.0100297
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) 0.00995221
NPEPL1 aminopeptidase-like 1 0.00993471
CDK5RAP3 CDK5 regulatory subunit associated protein 3 0.00984772
TARDBP TAR DNA binding protein 0.00971734
CCNL2 cyclin L2 0.00957749
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 0.00955905
BRD4 bromodomain containing 4 0.00951668
CIT citron rho-interacting serine/threonine kinase 0.00951454
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor 0.00948908
TCERG1 transcription elongation regulator 1 0.00948627
TNK2 tyrosine kinase, non-receptor, 2 0.00943024
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.00942093
ADGRF5 adhesion G protein-coupled receptor F5 0.00938344
FBN2 fibrillin 2 0.00933488
PTP4A3 protein tyrosine phosphatase type IVA, member 3 0.00930856
SHB Src homology 2 domain containing adaptor protein B 0.00924202
KAZN kazrin, periplakin interacting protein 0.00916259
LUC7L3 LUC7-like 3 (S. cerevisiae) 0.00912687
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 0.00912121
WSB1 WD repeat and SOCS box containing 1 0.00909535
KANK1 KN motif and ankyrin repeat domains 1 0.00908292
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 0.00906311
PLAAT3 phospholipase A and acyltransferase 3 0.00904208
KIF5B kinesin family member 5B 0.00899198
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor 0.00893277
AMOTL2 angiomotin like 2 0.00892285
VTCN1 V-set domain containing T cell activation inhibitor 1 0.00884347
RCAN2 regulator of calcineurin 2 0.00878242
PLXNA1 plexin A1 0.00875605
HMGB3 high mobility group box 3 0.00874016
RRBP1 ribosome binding protein 1 0.00872935
SRRT serrate, RNA effector molecule 0.00866646
PRRC2A proline-rich coiled-coil 2A 0.00863957
ZBTB20 zinc finger and BTB domain containing 20 0.008624
ACADVL acyl-CoA dehydrogenase, very long chain 0.00859688
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 0.00856212
MSANTD2 Myb/SANT-like DNA-binding domain containing 2 0.0085567
LPCAT1 lysophosphatidylcholine acyltransferase 1 0.0085419
MTA1 metastasis associated 1 0.00851393
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1 0.00849705
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 0.00847501
SLC4A2 solute carrier family 4 (anion exchanger), member 2 0.00847479
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit 0.00846284
WWC3 WWC family member 3 0.00845924
TIMP3 TIMP metallopeptidase inhibitor 3 0.00845786
GATA2 GATA binding protein 2 0.00845711
NKTR natural killer cell triggering receptor 0.00843651
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 0.00841932
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 0.00837884
TRRAP transformation/transcription domain-associated protein 0.00837567
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 0.00837199
SMTN smoothelin 0.0083658
CREB3L2 cAMP responsive element binding protein 3-like 2 0.00836462
OTUD3 OTU deubiquitinase 3 0.00834824
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa 0.0082721
NAV2 neuron navigator 2 0.00825776
STK25 serine/threonine kinase 25 0.00825603
RAPSN receptor-associated protein of the synapse 0.0082344
IPO9 importin 9 0.00823027
JAG1 jagged 1 0.00822439
KLK5 kallikrein-related peptidase 5 0.0082186
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.00820318
CBX1 chromobox homolog 1 0.0081773
NOTCH1 notch 1 0.00814916
P3H2 prolyl 3-hydroxylase 2 0.00814561
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 0.00814089
TSC22D4 TSC22 domain family, member 4 0.00812389
NXF1 nuclear RNA export factor 1 0.00812384
SPIN1 spindlin 1 0.00807487
KLK11 kallikrein-related peptidase 11 0.00806418
RTN3 reticulon 3 0.00805727
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 0.00804427
WDR6 WD repeat domain 6 0.0080301
DGKZ diacylglycerol kinase, zeta 0.00800668
ANKRD11 ankyrin repeat domain 11 0.00799303
AUTS2 autism susceptibility candidate 2 0.00798639
SMAD7 SMAD family member 7 0.00798443
RXRA retinoid X receptor, alpha 0.00797239
HNRNPM heterogeneous nuclear ribonucleoprotein M 0.0078829
NR5A1 nuclear receptor subfamily 5, group A, member 1 0.00788228
EXOC7 exocyst complex component 7 0.0078368
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 0.00782757
ELAC2 elaC ribonuclease Z 2 0.00782396
REC8 REC8 meiotic recombination protein 0.00781315
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 0.00780988
CBX5 chromobox homolog 5 0.00779469
SPATA20 spermatogenesis associated 20 0.00778707
MINK1 misshapen-like kinase 1 0.00776516
DOCK9 dedicator of cytokinesis 9 0.00775838
USP32P2 ubiquitin specific peptidase 32 pseudogene 2 0.00775298
TYMS thymidylate synthetase 0.0077416
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 0.00773668
SRRM2 serine/arginine repetitive matrix 2 0.00772957
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 0.00770306
RAB8A RAB8A, member RAS oncogene family 0.00768402
CCDC92 coiled-coil domain containing 92 0.00768055
ANKRD10 ankyrin repeat domain 10 0.0076799
SPEN spen family transcriptional repressor 0.00763355
CAPN15 calpain 15 0.00763102
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 0.00759962
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 0.00757411
NPIPA1 nuclear pore complex interacting protein family, member A1 0.00756107
MED13 mediator complex subunit 13 0.00756075
PCDH17 protocadherin 17 0.00753648
ELN elastin 0.00752975
CTNND1 catenin (cadherin-associated protein), delta 1 0.00752273
PGC progastricsin (pepsinogen C) 0.00752213
DVL1 dishevelled segment polarity protein 1 0.00751525
TSPAN12 tetraspanin 12 0.00750851
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 0.00750061
PRPF8 pre-mRNA processing factor 8 0.00748002
PTBP1 polypyrimidine tract binding protein 1 0.00747667
SOX9 SRY (sex determining region Y)-box 9 0.00746013
MPRIP myosin phosphatase Rho interacting protein 0.00742154
WIZ widely interspaced zinc finger motifs 0.00739987
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.0073951
SFN stratifin 0.00736246
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 0.00734111
IRAK1 interleukin-1 receptor-associated kinase 1 0.00733736
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 0.00733556
CEP350 centrosomal protein 350kDa 0.00730494
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.00730267
UCKL1 uridine-cytidine kinase 1-like 1 0.00729458
COL4A5 collagen, type IV, alpha 5 0.00728376
WASL Wiskott-Aldrich syndrome-like 0.00727732
CPB1 carboxypeptidase B1 (tissue) 0.00725726
CXCL14 chemokine (C-X-C motif) ligand 14 0.00725372
FSTL1 follistatin-like 1 0.00725216
GEMIN4 gem (nuclear organelle) associated protein 4 0.00723878
PIEZO1 piezo-type mechanosensitive ion channel component 1 0.00723506
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) 0.00722505
TRIM44 tripartite motif containing 44 0.0072181
AGRN agrin 0.00720628
ADARB1 adenosine deaminase, RNA-specific, B1 0.00720483
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 0.00720204
FBLN2 fibulin 2 0.00720197
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.00719027
MTCL1 microtubule crosslinking factor 1 0.00718859
ARGLU1 arginine and glutamate rich 1 0.00718384
FBXW12 F-box and WD repeat domain containing 12 0.00716619
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 0.00716156
TECR trans-2,3-enoyl-CoA reductase 0.00716139
KCTD14 potassium channel tetramerization domain containing 14 0.00716133
DAPK3 death-associated protein kinase 3 0.00715676
KMT5B lysine methyltransferase 5B 0.00711752
GATAD2A GATA zinc finger domain containing 2A 0.00710277
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 0.00709873
MDC1 mediator of DNA-damage checkpoint 1 0.00707858
COL9A2 collagen, type IX, alpha 2 0.00707222
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 0.00706678
AP3D1 adaptor-related protein complex 3, delta 1 subunit 0.00705827
ATXN7 ataxin 7 0.00703543
TP53I11 tumor protein p53 inducible protein 11 0.00702267
ALAS1 5'-aminolevulinate synthase 1 0.00701455
EIF3B eukaryotic translation initiation factor 3, subunit B 0.00700538
SGSM2 small G protein signaling modulator 2 0.00700287
TCEA2 transcription elongation factor A (SII), 2 0.00700069
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.00700018
USP48 ubiquitin specific peptidase 48 0.00699154
BST2 bone marrow stromal cell antigen 2 0.00698424
CLUH clustered mitochondria (cluA/CLU1) homolog 0.00697522
DAZAP1 DAZ associated protein 1 0.00695826
CIC capicua transcriptional repressor 0.00695431
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.00695402
DIPK1A divergent protein kinase domain 1A 0.00693593
LRFN4 leucine rich repeat and fibronectin type III domain containing 4 0.00693064
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.00692988
AKAP8 A kinase (PRKA) anchor protein 8 0.00692979
MCM7 minichromosome maintenance complex component 7 0.00691734
DLG1 discs, large homolog 1 (Drosophila) 0.00691595
PFAS phosphoribosylformylglycinamidine synthase 0.00690849
SCRIB scribbled planar cell polarity protein 0.00690391
GAS6 growth arrest-specific 6 0.00689321
BAHCC1 BAH domain and coiled-coil containing 1 0.00688145
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like 0.00687912
EMP3 epithelial membrane protein 3 0.00687647
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) 0.00687134
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1 0.00686186
NUP188 nucleoporin 188kDa 0.00685911
CROCCP2 ciliary rootlet coiled-coil, rootletin pseudogene 2 0.00685901
AZU1 azurocidin 1 0.00685205
PKD1 polycystic kidney disease 1 (autosomal dominant) 0.00681498
PNPLA6 patatin-like phospholipase domain containing 6 0.0068109
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2 0.00680406
SDC3 syndecan 3 0.00679473
INPPL1 inositol polyphosphate phosphatase-like 1 0.00678492
MYC v-myc avian myelocytomatosis viral oncogene homolog 0.00678402
PLK2 polo-like kinase 2 0.00678001
ATP13A1 ATPase type 13A1 0.00677637
MN1 meningioma (disrupted in balanced translocation) 1 0.00677547
NISCH nischarin 0.00675297
HTATSF1 HIV-1 Tat specific factor 1 0.00675148
COL16A1 collagen, type XVI, alpha 1 0.0067486
SAFB scaffold attachment factor B 0.00674747
DGKD diacylglycerol kinase, delta 130kDa 0.00674155
DENND4B DENN/MADD domain containing 4B 0.00673437
PWWP3A PWWP domain containing 3A, DNA repair factor 0.00673322
MAPKBP1 mitogen-activated protein kinase binding protein 1 0.00671843
EVA1B eva-1 homolog B (C. elegans) 0.0067172
TENT4A terminal nucleotidyltransferase 4A 0.00670994
CDK11A cyclin-dependent kinase 11A 0.00669882
SIX1 SIX homeobox 1 0.00669033
SMAD6 SMAD family member 6 0.00668814
GRAMD4 GRAM domain containing 4 0.00668703
DDAH1 dimethylarginine dimethylaminohydrolase 1 0.00665633
SAFB2 scaffold attachment factor B2 0.00665497
RPA1 replication protein A1, 70kDa 0.00662933
USP22 ubiquitin specific peptidase 22 0.00662763
DGAT1 diacylglycerol O-acyltransferase 1 0.00662351
MSL2 male-specific lethal 2 homolog (Drosophila) 0.00660662
TNPO2 transportin 2 0.00660579
MOK MOK protein kinase 0.00659484
LONP2 lon peptidase 2, peroxisomal 0.00658749
KIF14 kinesin family member 14 0.00658031
PKD1P1 polycystic kidney disease 1 (autosomal dominant) pseudogene 1 0.00657194
PMPCA peptidase (mitochondrial processing) alpha 0.00656629
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 0.00656095
DAPK1 death-associated protein kinase 1 0.00655927

decreased expression

Symbol Name Standardized Value
MT1F metallothionein 1F -0.0157958
MT1X metallothionein 1X -0.0157846
DAXX death-domain associated protein -0.014909
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -0.0147946
SSBP2 single-stranded DNA binding protein 2 -0.0142775
NEBL nebulette -0.0138903
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 -0.0137338
CD52 CD52 molecule -0.0134765
CLCA4 chloride channel accessory 4 -0.0133528
LUM lumican -0.0132045
ISG20 interferon stimulated exonuclease gene 20kDa -0.0130591
MMP12 matrix metallopeptidase 12 -0.0130429
THBS2 thrombospondin 2 -0.0130195
MAL mal, T-cell differentiation protein -0.0129826
MME membrane metallo-endopeptidase -0.0125638
MT1G metallothionein 1G -0.0125348
CD59 CD59 molecule, complement regulatory protein -0.0120814
TFF1 trefoil factor 1 -0.0120745
SELL selectin L -0.0120528
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.0120476
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 -0.012003
PLP1 proteolipid protein 1 -0.011976
LXN latexin -0.0119411
XPO7 exportin 7 -0.0115721
MT1HL1 metallothionein 1H-like 1 -0.0114635
UGP2 UDP-glucose pyrophosphorylase 2 -0.0114106
MT1H metallothionein 1H -0.0113947
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 -0.0113946
PSAP prosaposin -0.0113617
CHGB chromogranin B -0.0113098
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 -0.011277
GRB7 growth factor receptor-bound protein 7 -0.0111514
CTSS cathepsin S -0.0110754
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) -0.0109814
IFI16 interferon, gamma-inducible protein 16 -0.0108828
CLDN8 claudin 8 -0.0107531
FABP7 fatty acid binding protein 7, brain -0.0107343
FXYD3 FXYD domain containing ion transport regulator 3 -0.0106712
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -0.0106242
HLA-DRA major histocompatibility complex, class II, DR alpha -0.010612
MT2A metallothionein 2A -0.0105807
VCAN versican -0.0104853
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.0103431
TSPAN31 tetraspanin 31 -0.0103309
TPD52L1 tumor protein D52-like 1 -0.010179
PCSK1 proprotein convertase subtilisin/kexin type 1 -0.0101477
KRT13 keratin 13, type I -0.0100574
KYNU kynureninase -0.0100556
GPNMB glycoprotein (transmembrane) nmb -0.0100186
CD200 CD200 molecule -0.00989497
LMCD1 LIM and cysteine-rich domains 1 -0.00985355
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.00977786
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.00975489
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -0.00972739
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 -0.00968846
RGS10 regulator of G-protein signaling 10 -0.00961512
MT1M metallothionein 1M -0.00961
DNTT DNA nucleotidylexotransferase -0.00958423
SYT1 synaptotagmin I -0.00957415
GYPC glycophorin C (Gerbich blood group) -0.00955919
PDE4B phosphodiesterase 4B, cAMP-specific -0.00954903
C1ORF54 chromosome 1 open reading frame 54 -0.00946086
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 -0.00943453
BEX4 brain expressed, X-linked 4 -0.00940488
DCN decorin -0.00938955
NDN necdin, melanoma antigen (MAGE) family member -0.00937956
HSPB1 heat shock 27kDa protein 1 -0.00935442
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -0.0092969
ACOX2 acyl-CoA oxidase 2, branched chain -0.00929238
RCAN1 regulator of calcineurin 1 -0.00927127
CD27 CD27 molecule -0.00920541
CHMP1B charged multivesicular body protein 1B -0.00919029
TSC22D1 TSC22 domain family, member 1 -0.00918182
SPON1 spondin 1, extracellular matrix protein -0.0091806
MYO1C myosin IC -0.00909715
C8ORF4 chromosome 8 open reading frame 4 -0.0090775
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 -0.00905992
CXADR coxsackie virus and adenovirus receptor -0.00904349
PPP1R16B protein phosphatase 1, regulatory subunit 16B -0.00903763
PIK3IP1 phosphoinositide-3-kinase interacting protein 1 -0.00903649
ATG5 autophagy related 5 -0.00903161
RSL1D1 ribosomal L1 domain containing 1 -0.00898101
GDI2 GDP dissociation inhibitor 2 -0.00898096
GPM6B glycoprotein M6B -0.00894525
SRPX2 sushi-repeat containing protein, X-linked 2 -0.00893397
PADI2 peptidyl arginine deiminase, type II -0.00890746
CXCL12 chemokine (C-X-C motif) ligand 12 -0.00890166
MLF1 myeloid leukemia factor 1 -0.0088913
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 -0.00889119
LAMP3 lysosomal-associated membrane protein 3 -0.00886737
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa -0.00885575
MKNK2 MAP kinase interacting serine/threonine kinase 2 -0.00881143
CAST calpastatin -0.00879871
MED6 mediator complex subunit 6 -0.00878866
PRKACB protein kinase, cAMP-dependent, catalytic, beta -0.00876376
CRABP1 cellular retinoic acid binding protein 1 -0.00871559
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -0.0087002
MAP2K6 mitogen-activated protein kinase kinase 6 -0.0086773
BPHL biphenyl hydrolase-like (serine hydrolase) -0.00866005
BCL2A1 BCL2-related protein A1 -0.00865333
SLC26A3 solute carrier family 26 (anion exchanger), member 3 -0.00865052
LY96 lymphocyte antigen 96 -0.0086474
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide -0.00864434
ADAT1 adenosine deaminase, tRNA-specific 1 -0.00863089
DMAC2L distal membrane arm assembly component 2 like -0.00862252
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7 -0.00860984
BAMBI BMP and activin membrane-bound inhibitor -0.00860642
QPCT glutaminyl-peptide cyclotransferase -0.00853441
YPEL5 yippee-like 5 (Drosophila) -0.0085001
IRF6 interferon regulatory factor 6 -0.00846715
COX4I1 cytochrome c oxidase subunit IV isoform 1 -0.00844975
STON1 stonin 1 -0.00843781
INHBA inhibin, beta A -0.00843727
CRELD2 cysteine-rich with EGF-like domains 2 -0.00842063
RGS13 regulator of G-protein signaling 13 -0.00841521
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 -0.00840515
CHN1 chimerin 1 -0.00840187
LY75 lymphocyte antigen 75 -0.00839766
RETREG1 reticulophagy regulator 1 -0.00835908
SOX10 SRY (sex determining region Y)-box 10 -0.00835378
TSPAN1 tetraspanin 1 -0.00835021
ERP44 endoplasmic reticulum protein 44 -0.00831609
DHRS9 dehydrogenase/reductase (SDR family) member 9 -0.00831455
EAPP E2F-associated phosphoprotein -0.00830161
FAR2 fatty acyl CoA reductase 2 -0.00828868
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 -0.00827175
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 -0.00820395
ATRAID all-trans retinoic acid-induced differentiation factor -0.0081505
CLDN7 claudin 7 -0.0081406
CCT4 chaperonin containing TCP1, subunit 4 (delta) -0.00812681
GBP2 guanylate binding protein 2, interferon-inducible -0.00811633
CEMIP cell migration inducing protein, hyaluronan binding -0.00810747
DDIT4 DNA-damage-inducible transcript 4 -0.00808174
TUBB2A tubulin, beta 2A class IIa -0.0080628
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) -0.00804651
LINC00623 long intergenic non-protein coding RNA 623 -0.00803767
TP53I3 tumor protein p53 inducible protein 3 -0.00803025
TBC1D15 TBC1 domain family, member 15 -0.00801644
JCHAIN joining chain of multimeric IgA and IgM -0.00797889
SEZ6L2 seizure related 6 homolog (mouse)-like 2 -0.00796949
RBKS ribokinase -0.00796883
GNG4 guanine nucleotide binding protein (G protein), gamma 4 -0.00793523
ERAP2 endoplasmic reticulum aminopeptidase 2 -0.00792413
LTF lactotransferrin -0.00789884
CFH complement factor H -0.00787868
MS4A12 membrane-spanning 4-domains, subfamily A, member 12 -0.00786025
GSTO1 glutathione S-transferase omega 1 -0.00785798
SELENBP1 selenium binding protein 1 -0.00781044
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -0.00779123
BFAR bifunctional apoptosis regulator -0.00775464
CXCL5 chemokine (C-X-C motif) ligand 5 -0.00773891
UQCRC2 ubiquinol-cytochrome c reductase core protein II -0.0077309
CCNG1 cyclin G1 -0.00770914
PECR peroxisomal trans-2-enoyl-CoA reductase -0.0077012
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -0.00769572
STMN2 stathmin 2 -0.0076883
IL7R interleukin 7 receptor -0.00768554
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent -0.00768553
DAZAP2 DAZ associated protein 2 -0.0076596
RNF128 ring finger protein 128, E3 ubiquitin protein ligase -0.00764928
KIAA0226L KIAA0226-like -0.00763003
RPP40 ribonuclease P/MRP 40kDa subunit -0.00762673
RPA2 replication protein A2, 32kDa -0.00760626
GLIPR1 GLI pathogenesis-related 1 -0.00758736
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits -0.00756954
KRT19 keratin 19, type I -0.00756648
RNF144A ring finger protein 144A -0.00755834
EGR2 early growth response 2 -0.00755355
TMEM59 transmembrane protein 59 -0.00753889
LCP1 lymphocyte cytosolic protein 1 (L-plastin) -0.00753407
HSPA4 heat shock 70kDa protein 4 -0.00753084
STOM stomatin -0.00750593
ANXA1 annexin A1 -0.00750495
GPR137B G protein-coupled receptor 137B -0.00750149
GLUD2 glutamate dehydrogenase 2 -0.00749746
DHTKD1 dehydrogenase E1 and transketolase domain containing 1 -0.00748825
S100A10 S100 calcium binding protein A10 -0.00748714
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) -0.00747307
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 -0.00744108
CFI complement factor I -0.00743737
ETHE1 ethylmalonic encephalopathy 1 -0.00743253
CD86 CD86 molecule -0.00743218
ACP3 acid phosphatase 3 -0.00742787
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 -0.00742236
IFITM1 interferon induced transmembrane protein 1 -0.00741708
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -0.00741656
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 -0.00741228
EVI2A ecotropic viral integration site 2A -0.00737813
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 -0.00737374
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) -0.00737285
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 -0.00735349
GREM1 gremlin 1, DAN family BMP antagonist -0.00735049
EDN3 endothelin 3 -0.00734578
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -0.00733822
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00730734
SH3GL2 SH3-domain GRB2-like 2 -0.00730483
DUSP22 dual specificity phosphatase 22 -0.00729991
VAMP8 vesicle-associated membrane protein 8 -0.00724609
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -0.00724115
TXNL4B thioredoxin-like 4B -0.00723605
SNX13 sorting nexin 13 -0.00723131
ADAMDEC1 ADAM-like, decysin 1 -0.00721789
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) -0.00721756
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -0.00720983
ATF3 activating transcription factor 3 -0.00719147
RFC2 replication factor C (activator 1) 2, 40kDa -0.00715944
CXCL8 chemokine (C-X-C motif) ligand 8 -0.00715164
REL v-rel avian reticuloendotheliosis viral oncogene homolog -0.00714998
PIGP phosphatidylinositol glycan anchor biosynthesis, class P -0.00714981
C10ORF10 chromosome 10 open reading frame 10 -0.00714233
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 -0.00713384
KRT15 keratin 15, type I -0.00712534
C1S complement component 1, s subcomponent -0.00712318
HSBP1 heat shock factor binding protein 1 -0.0071154
INA internexin neuronal intermediate filament protein, alpha -0.00711064
MMP10 matrix metallopeptidase 10 -0.00710994
LMO2 LIM domain only 2 (rhombotin-like 1) -0.00708902
CREM cAMP responsive element modulator -0.00708888
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 -0.00708301
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 -0.00707806
RAI14 retinoic acid induced 14 -0.00707181
RAB29 RAB29, member RAS oncogene family -0.00706589
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -0.00706493
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 -0.00706154
SRPX sushi-repeat containing protein, X-linked -0.00704499
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa -0.00703506
LSP1 lymphocyte-specific protein 1 -0.00702214
SLC30A1 solute carrier family 30 (zinc transporter), member 1 -0.00701595
PRKD3 protein kinase D3 -0.00701515
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.00700416
PEX2 peroxisomal biogenesis factor 2 -0.00699202
SINHCAF SIN3-HDAC complex associated factor -0.00697371
RAB8B RAB8B, member RAS oncogene family -0.00696763
ELF1 E74-like factor 1 (ets domain transcription factor) -0.00696371
GAP43 growth associated protein 43 -0.00695915
AP1S1 adaptor-related protein complex 1, sigma 1 subunit -0.00693209
ANXA2P2 annexin A2 pseudogene 2 -0.00692021
RRAS2 related RAS viral (r-ras) oncogene homolog 2 -0.00691888
SOSTDC1 sclerostin domain containing 1 -0.00691243
CALB1 calbindin 1, 28kDa -0.00690271
ATP5F1C ATP synthase F1 subunit gamma -0.00688792
TMEM14B transmembrane protein 14B -0.0068607
MRPL19 mitochondrial ribosomal protein L19 -0.00686026
S100B S100 calcium binding protein B -0.00685075
PDE8B phosphodiesterase 8B -0.00684903
ACP5 acid phosphatase 5, tartrate resistant -0.00684498
IL15 interleukin 15 -0.00684161
MRPL33 mitochondrial ribosomal protein L33 -0.0068283
LPXN leupaxin -0.0068267
RMDN1 regulator of microtubule dynamics 1 -0.00681864