ROCK2 Gene Set

Dataset PhosphoSitePlus Substrates of Kinases
Category physical interactions
Type kinase
Description Rho-associated, coiled-coil containing protein kinase 2|The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 9475)
External Link
Similar Terms
Downloads & Tools


19 substrates of the kinase ROCK2 from the curated PhosphoSitePlus Substrates of Kinases dataset.

Symbol Name
APP amyloid beta (A4) precursor protein
BACE1 beta-site APP-cleaving enzyme 1
CNN3 calponin 3, acidic
DPYSL2 dihydropyrimidinase-like 2
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
EZR ezrin
IRF4 interferon regulatory factor 4
IRS1 insulin receptor substrate 1
LIMK2 LIM domain kinase 2
MSN moesin
MYL12B myosin, light chain 12B, regulatory
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B
RDX radixin
SH3GL2 SH3-domain GRB2-like 2
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
TNNI3 troponin I type 3 (cardiac)