ROCK2_knockdown_157_GSE34769 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Kinase Perturbations
Category transcriptomics
Type kinase perturbation
Description kinase perturbation identified as [kinase gene symbol]_[perturbation]_[perturbation ID]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE34769
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Genes

600 genes differentially expressed following the ROCK2_knockdown_157_GSE34769 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.

increased expression

Symbol Name Standardized Value
SPRR1A small proline-rich protein 1A 4.28199
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 3.70049
ARRDC2 arrestin domain containing 2 3.47557
KCNE3 potassium channel, voltage gated subfamily E regulatory beta subunit 3 3.46352
GDF15 growth differentiation factor 15 3.45062
EGR1 early growth response 1 3.35544
GSTM4 glutathione S-transferase mu 4 3.17919
HLX H2.0-like homeobox 3.0607
DGUOK deoxyguanosine kinase 3.04165
ISG15 ISG15 ubiquitin-like modifier 3.01464
CXCL2 chemokine (C-X-C motif) ligand 2 2.96518
PLAU plasminogen activator, urokinase 2.85921
GSS glutathione synthetase 2.84558
BTBD19 BTB (POZ) domain containing 19 2.77587
CLSTN3 calsyntenin 3 2.76962
KLRG2 killer cell lectin-like receptor subfamily G, member 2 2.76376
IFI27L1 interferon, alpha-inducible protein 27-like 1 2.75828
DCPS decapping enzyme, scavenger 2.72026
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 2.71406
GFM1 G elongation factor, mitochondrial 1 2.71377
KRT19 keratin 19, type I 2.68254
HS6ST2 heparan sulfate 6-O-sulfotransferase 2 2.67486
IRF7 interferon regulatory factor 7 2.66994
GADD45B growth arrest and DNA-damage-inducible, beta 2.66515
RAB20 RAB20, member RAS oncogene family 2.61917
LGMN legumain 2.60905
RHOT2 ras homolog family member T2 2.58684
IL20RB interleukin 20 receptor beta 2.5814
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) 2.57331
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 2.54598
PLTP phospholipid transfer protein 2.54207
SNX20 sorting nexin 20 2.53417
FOSB FBJ murine osteosarcoma viral oncogene homolog B 2.53302
DBP D site of albumin promoter (albumin D-box) binding protein 2.4805
TMC6 transmembrane channel-like 6 2.47415
ZGPAT zinc finger, CCCH-type with G patch domain 2.46544
GMPS guanine monphosphate synthase 2.44719
IRF8 interferon regulatory factor 8 2.43701
ATF3 activating transcription factor 3 2.43304
GAP43 growth associated protein 43 2.42372
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 2.42311
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa 2.41746
ERRFI1 ERBB receptor feedback inhibitor 1 2.41636
GRAMD1B GRAM domain containing 1B 2.41047
NAGK N-acetylglucosamine kinase 2.40577
CCL5 chemokine (C-C motif) ligand 5 2.4028
ARHGAP22 Rho GTPase activating protein 22 2.39415
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme 2.39141
CMPK2 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial 2.38767
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 2.38622
SGCE sarcoglycan, epsilon 2.3787
CACNG1 calcium channel, voltage-dependent, gamma subunit 1 2.37531
REEP6 receptor accessory protein 6 2.37463
SSH1 slingshot protein phosphatase 1 2.37018
TNXB tenascin XB 2.36964
DUSP7 dual specificity phosphatase 7 2.34074
FGFBP1 fibroblast growth factor binding protein 1 2.32759
SLC39A4 solute carrier family 39 (zinc transporter), member 4 2.32402
IRF9 interferon regulatory factor 9 2.3085
CXCL10 chemokine (C-X-C motif) ligand 10 2.30324
MSMP microseminoprotein, prostate associated 2.29996
ITPKC inositol-trisphosphate 3-kinase C 2.29487
HDC histidine decarboxylase 2.29449
GBP2 guanylate binding protein 2, interferon-inducible 2.28877
GBA glucosidase, beta, acid 2.27932
ZBTB12 zinc finger and BTB domain containing 12 2.27221
JUN jun proto-oncogene 2.27161
FAT2 FAT atypical cadherin 2 2.27032
IER5 immediate early response 5 2.26831
HVCN1 hydrogen voltage gated channel 1 2.25482
TRIB3 tribbles pseudokinase 3 2.24841
PNRC2 proline-rich nuclear receptor coactivator 2 2.22724
ATP6V0E2 ATPase, H+ transporting V0 subunit e2 2.21646
UNC45A unc-45 homolog A (C. elegans) 2.19174
EPHA2 EPH receptor A2 2.18481
CLU clusterin 2.16424
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 2.16232
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 2.16083
ZBTB17 zinc finger and BTB domain containing 17 2.14706
LGI2 leucine-rich repeat LGI family, member 2 2.14641
NDRG1 N-myc downstream regulated 1 2.14177
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) 2.12521
IFI44 interferon-induced protein 44 2.11654
IL24 interleukin 24 2.11069
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 2.10801
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 2.075
ARRDC3 arrestin domain containing 3 2.07337
USP18 ubiquitin specific peptidase 18 2.06003
SH2B1 SH2B adaptor protein 1 2.05619
MTFP1 mitochondrial fission process 1 2.04707
HES1 hes family bHLH transcription factor 1 2.04402
LRWD1 leucine-rich repeats and WD repeat domain containing 1 2.03995
GBP6 guanylate binding protein family, member 6 2.03478
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 2.03427
PARP8 poly (ADP-ribose) polymerase family, member 8 2.03411
LEPROT leptin receptor overlapping transcript 2.02065
CCNG2 cyclin G2 2.01599
STAT2 signal transducer and activator of transcription 2, 113kDa 2.01496
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 2.01475
ALOXE3 arachidonate lipoxygenase 3 2.01411
EARS2 glutamyl-tRNA synthetase 2, mitochondrial 2.01288
ETV4 ets variant 4 2.00608
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 2.00563
GEM GTP binding protein overexpressed in skeletal muscle 2.00236
VCAM1 vascular cell adhesion molecule 1 1.9966
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 1.98887
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 1.98752
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 1.98382
E2F2 E2F transcription factor 2 1.97818
NME7 NME/NM23 family member 7 1.97696
SPOP speckle-type POZ protein 1.97416
PDIA4 protein disulfide isomerase family A, member 4 1.95392
TXNIP thioredoxin interacting protein 1.94876
DLL4 delta-like 4 (Drosophila) 1.93439
PARP1 poly (ADP-ribose) polymerase 1 1.92497
PDK4 pyruvate dehydrogenase kinase, isozyme 4 1.92215
DUSP6 dual specificity phosphatase 6 1.91652
MAPK12 mitogen-activated protein kinase 12 1.91575
ANXA5 annexin A5 1.91513
MAP3K8 mitogen-activated protein kinase kinase kinase 8 1.90646
DUS4L dihydrouridine synthase 4-like (S. cerevisiae) 1.90533
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 1.90445
ZFP69 ZFP69 zinc finger protein 1.90037
PRELID2 PRELI domain containing 2 1.89756
UPP1 uridine phosphorylase 1 1.89622
AIP aryl hydrocarbon receptor interacting protein 1.89391
EFNA1 ephrin-A1 1.88797
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 1.88591
BHLHE40 basic helix-loop-helix family, member e40 1.88541
FLOT1 flotillin 1 1.8846
PIM1 Pim-1 proto-oncogene, serine/threonine kinase 1.88297
PARP9 poly (ADP-ribose) polymerase family, member 9 1.88035
PDLIM1 PDZ and LIM domain 1 1.87507
FAM180A family with sequence similarity 180, member A 1.87503
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 1.87381
GBP3 guanylate binding protein 3 1.87302
RASGEF1B RasGEF domain family, member 1B 1.86983
CKB creatine kinase, brain 1.86506
AP3B1 adaptor-related protein complex 3, beta 1 subunit 1.85891
C3 complement component 3 1.85626
PVRL4 poliovirus receptor-related 4 1.85484
BTBD6 BTB (POZ) domain containing 6 1.85422
OPTN optineurin 1.85379
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) 1.85283
LMCD1 LIM and cysteine-rich domains 1 1.8516
AP4M1 adaptor-related protein complex 4, mu 1 subunit 1.85087
MBLAC1 metallo-beta-lactamase domain containing 1 1.84924
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 1.84844
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta 1.84676
IPO4 importin 4 1.84499
EGLN3 egl-9 family hypoxia-inducible factor 3 1.84386
PLK2 polo-like kinase 2 1.83895
GADD45A growth arrest and DNA-damage-inducible, alpha 1.83691
RTKN rhotekin 1.83044
GADD45G growth arrest and DNA-damage-inducible, gamma 1.82676
ECHDC3 enoyl CoA hydratase domain containing 3 1.81213
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 1.8085
OMA1 OMA1 zinc metallopeptidase 1.80771
ITPRIP inositol 1,4,5-trisphosphate receptor interacting protein 1.80393
FARSB phenylalanyl-tRNA synthetase, beta subunit 1.80238
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 1.79181
KDM6A lysine (K)-specific demethylase 6A 1.79014
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 1.78652
RPTOR regulatory associated protein of MTOR, complex 1 1.7854
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) 1.78413
FOSL1 FOS-like antigen 1 1.77896
GSTO2 glutathione S-transferase omega 2 1.77665
RHOB ras homolog family member B 1.76995
CXCR4 chemokine (C-X-C motif) receptor 4 1.7691
ANKS6 ankyrin repeat and sterile alpha motif domain containing 6 1.76577
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3 1.76393
TPD52L1 tumor protein D52-like 1 1.75902
TRIM47 tripartite motif containing 47 1.75129
IFT74 intraflagellar transport 74 1.75083
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.75031
RBMX2 RNA binding motif protein, X-linked 2 1.75022
FRZB frizzled-related protein 1.74778
IER2 immediate early response 2 1.74727
HSPA4L heat shock 70kDa protein 4-like 1.74009
MANBA mannosidase, beta A, lysosomal 1.73737
TBRG1 transforming growth factor beta regulator 1 1.73348
ATG16L2 autophagy related 16-like 2 (S. cerevisiae) 1.73144
EPDR1 ependymin related 1 1.72811
RDH5 retinol dehydrogenase 5 (11-cis/9-cis) 1.72362
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) 1.72333
ATF6B activating transcription factor 6 beta 1.71951
DDIT3 DNA-damage-inducible transcript 3 1.71581
LAT2 linker for activation of T cells family, member 2 1.71343
SPSB2 splA/ryanodine receptor domain and SOCS box containing 2 1.71287
ITGA6 integrin, alpha 6 1.71211
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 1.70874
VPS26A vacuolar protein sorting 26 homolog A (S. pombe) 1.7053
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 1.70494
PNPLA7 patatin-like phospholipase domain containing 7 1.70382
CDCA8 cell division cycle associated 8 1.70248
ATF7IP activating transcription factor 7 interacting protein 1.70034
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.69929
EGR2 early growth response 2 1.69808
DERA deoxyribose-phosphate aldolase (putative) 1.69645
JUNB jun B proto-oncogene 1.69568
ZFP3 ZFP3 zinc finger protein 1.69547
FDXR ferredoxin reductase 1.69331
COL8A1 collagen, type VIII, alpha 1 1.68306
FAS Fas cell surface death receptor 1.68202
TTL tubulin tyrosine ligase 1.67539
MFGE8 milk fat globule-EGF factor 8 protein 1.67535
RHBDL3 rhomboid, veinlet-like 3 (Drosophila) 1.67523
STX6 syntaxin 6 1.67298
GPR146 G protein-coupled receptor 146 1.66181
LTA4H leukotriene A4 hydrolase 1.66037
LRRC16A leucine rich repeat containing 16A 1.65465
IFI35 interferon-induced protein 35 1.65277
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 1.65141
MRPL38 mitochondrial ribosomal protein L38 1.64864
HCLS1 hematopoietic cell-specific Lyn substrate 1 1.64683
GRN granulin 1.64074
CNTLN centlein, centrosomal protein 1.63964
ACSBG1 acyl-CoA synthetase bubblegum family member 1 1.63952
PLIN2 perilipin 2 1.63918
IGF2R insulin-like growth factor 2 receptor 1.63536
FOS FBJ murine osteosarcoma viral oncogene homolog 1.63218
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34 1.62949
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 1.62667
ILF2 interleukin enhancer binding factor 2 1.62482
SGK1 serum/glucocorticoid regulated kinase 1 1.62464
BBS7 Bardet-Biedl syndrome 7 1.62433
NAGLU N-acetylglucosaminidase, alpha 1.62423
ZW10 zw10 kinetochore protein 1.62355
PRMT6 protein arginine methyltransferase 6 1.62154
CDC45 cell division cycle 45 1.62038
SORD sorbitol dehydrogenase 1.61942
CHTF18 CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae) 1.613
MFSD8 major facilitator superfamily domain containing 8 1.61147
ANGEL2 angel homolog 2 (Drosophila) 1.61093
MRVI1 murine retrovirus integration site 1 homolog 1.61026
LRRN4CL LRRN4 C-terminal like 1.60967
CCL2 chemokine (C-C motif) ligand 2 1.60618
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 1.60599
IRS2 insulin receptor substrate 2 1.60191
KIAA1614 KIAA1614 1.59917
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2 1.5965
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 1.5924
IFT81 intraflagellar transport 81 1.58968
DTNB dystrobrevin, beta 1.58662
MNS1 meiosis-specific nuclear structural 1 1.586
DUSP5 dual specificity phosphatase 5 1.58041
MAPKAP1 mitogen-activated protein kinase associated protein 1 1.57992
UPK2 uroplakin 2 1.5776
PHACTR2 phosphatase and actin regulator 2 1.57227
ZFP36 ZFP36 ring finger protein 1.57001
F3 coagulation factor III (thromboplastin, tissue factor) 1.5696
LONRF3 LON peptidase N-terminal domain and ring finger 3 1.56827
AATK apoptosis-associated tyrosine kinase 1.5675
AGBL3 ATP/GTP binding protein-like 3 1.56749
MPDZ multiple PDZ domain protein 1.56612
AMDHD2 amidohydrolase domain containing 2 1.56156
NUPR1 nuclear protein, transcriptional regulator, 1 1.55765
PPAP2C phosphatidic acid phosphatase type 2C 1.55078
GSDMD gasdermin D 1.546
S100A7A S100 calcium binding protein A7A 1.54215
TNNT2 troponin T type 2 (cardiac) 1.54198
RNF213 ring finger protein 213 1.5352
CHD1L chromodomain helicase DNA binding protein 1-like 1.53391
PHF7 PHD finger protein 7 1.53372
DFNA5 deafness, autosomal dominant 5 1.53159
ALG1 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase 1.53151
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58 1.52837
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 1.52769
PARP3 poly (ADP-ribose) polymerase family, member 3 1.52461
POLA2 polymerase (DNA directed), alpha 2, accessory subunit 1.51746
KIF22 kinesin family member 22 1.51665
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 1.51634
NID1 nidogen 1 1.51433
HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 1.51395
MAPK11 mitogen-activated protein kinase 11 1.51318
RASA4 RAS p21 protein activator 4 1.51318
ACOT8 acyl-CoA thioesterase 8 1.50922
PPL periplakin 1.50826
INSIG2 insulin induced gene 2 1.50726
RHOV ras homolog family member V 1.50681
CCDC22 coiled-coil domain containing 22 1.50672
UQCRC1 ubiquinol-cytochrome c reductase core protein I 1.50621
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 1.50557
ITPRIPL2 inositol 1,4,5-trisphosphate receptor interacting protein-like 2 1.50546
SLC12A9 solute carrier family 12, member 9 1.50533
TBL3 transducin (beta)-like 3 1.50159
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 1.50109
ADCK5 aarF domain containing kinase 5 1.49791
NKAIN1 Na+/K+ transporting ATPase interacting 1 1.49583
TEAD4 TEA domain family member 4 1.4944
RFX5 regulatory factor X, 5 (influences HLA class II expression) 1.4919
ZFP36L1 ZFP36 ring finger protein-like 1 1.48951
RSAD2 radical S-adenosyl methionine domain containing 2 1.48595
TAPBP TAP binding protein (tapasin) 1.48522
MIB1 mindbomb E3 ubiquitin protein ligase 1 1.48427
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa 1.48265
CCL4 chemokine (C-C motif) ligand 4 1.4785
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 1.47706
MVP major vault protein 1.47211
RNPS1 RNA binding protein S1, serine-rich domain 1.47014

decreased expression

Symbol Name Standardized Value
BHLHB9 basic helix-loop-helix domain containing, class B, 9 -3.38245
PRRG3 proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane) -3.35636
LST1 leukocyte specific transcript 1 -3.2558
SPRR3 small proline-rich protein 3 -3.01642
KLK8 kallikrein-related peptidase 8 -2.99142
AQP3 aquaporin 3 (Gill blood group) -2.96412
MRAS muscle RAS oncogene homolog -2.94989
NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 -2.90099
CALCOCO1 calcium binding and coiled-coil domain 1 -2.88701
MAP3K11 mitogen-activated protein kinase kinase kinase 11 -2.86553
NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa -2.86501
MIDN midnolin -2.83743
L1TD1 LINE-1 type transposase domain containing 1 -2.80819
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived) -2.76515
EDN1 endothelin 1 -2.75507
ACVRL1 activin A receptor type II-like 1 -2.73985
LRRC32 leucine rich repeat containing 32 -2.72089
POMC proopiomelanocortin -2.71344
RNU11 RNA, U11 small nuclear -2.69736
EPHB4 EPH receptor B4 -2.69701
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 -2.64577
MAN1A2 mannosidase, alpha, class 1A, member 2 -2.60604
COPZ2 coatomer protein complex, subunit zeta 2 -2.58337
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -2.54774
RBMS2 RNA binding motif, single stranded interacting protein 2 -2.53984
UBTF upstream binding transcription factor, RNA polymerase I -2.52918
SNHG12 small nucleolar RNA host gene 12 -2.50357
SIRPA signal-regulatory protein alpha -2.48997
HK2 hexokinase 2 -2.48944
ITGB5 integrin, beta 5 -2.46401
SELM selenoprotein M -2.4632
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 -2.45985
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein -2.4553
FHL1 four and a half LIM domains 1 -2.44406
PDPN podoplanin -2.43833
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma -2.43775
ZBTB7A zinc finger and BTB domain containing 7A -2.41401
ALKBH1 alkB, alkylation repair homolog 1 (E. coli) -2.40554
CALR calreticulin -2.39827
TNC tenascin C -2.38124
HAVCR2 hepatitis A virus cellular receptor 2 -2.37586
SQRDL sulfide quinone reductase-like (yeast) -2.3678
PFN1 profilin 1 -2.361
FAM43A family with sequence similarity 43, member A -2.34926
BOLA3 bolA family member 3 -2.30039
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -2.29355
THBS3 thrombospondin 3 -2.27877
RHOU ras homolog family member U -2.27824
DUT deoxyuridine triphosphatase -2.27628
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta -2.26898
MRPL33 mitochondrial ribosomal protein L33 -2.2664
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa -2.26051
CREB3 cAMP responsive element binding protein 3 -2.25537
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 -2.24648
OST4 oligosaccharyltransferase 4 homolog (S. cerevisiae) -2.2411
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 -2.23983
TMEM50B transmembrane protein 50B -2.22937
RHOJ ras homolog family member J -2.224
VWF von Willebrand factor -2.2223
DDX19A DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A -2.20878
CAND1 cullin-associated and neddylation-dissociated 1 -2.19994
SRSF6 serine/arginine-rich splicing factor 6 -2.19856
USP40 ubiquitin specific peptidase 40 -2.1815
S100A13 S100 calcium binding protein A13 -2.17528
TARDBP TAR DNA binding protein -2.16954
FBLN2 fibulin 2 -2.16928
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 -2.16138
PRNP prion protein -2.15791
HOXA7 homeobox A7 -2.15778
CSAD cysteine sulfinic acid decarboxylase -2.15582
TIMP2 TIMP metallopeptidase inhibitor 2 -2.14472
RMRP RNA component of mitochondrial RNA processing endoribonuclease -2.14372
BACE1 beta-site APP-cleaving enzyme 1 -2.1386
PDRG1 p53 and DNA-damage regulated 1 -2.13823
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 -2.13694
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 -2.13436
PTP4A2 protein tyrosine phosphatase type IVA, member 2 -2.1242
S100A4 S100 calcium binding protein A4 -2.12018
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 -2.1193
CLEC2D C-type lectin domain family 2, member D -2.10828
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) -2.10742
MEOX1 mesenchyme homeobox 1 -2.08975
FAM19A1 family with sequence similarity 19 (chemokine (C-C motif)-like), member A1 -2.08725
WBP5 WW domain binding protein 5 -2.08547
SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 -2.06174
UFSP2 UFM1-specific peptidase 2 -2.06147
EXOSC6 exosome component 6 -2.05728
SNHG9 small nucleolar RNA host gene 9 -2.05727
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 -2.05409
MEIS3 Meis homeobox 3 -2.04566
SLC39A13 solute carrier family 39 (zinc transporter), member 13 -2.04436
COBL cordon-bleu WH2 repeat protein -2.03836
COL6A3 collagen, type VI, alpha 3 -2.03062
RPIA ribose 5-phosphate isomerase A -2.02361
NR2F2 nuclear receptor subfamily 2, group F, member 2 -2.02156
FLRT3 fibronectin leucine rich transmembrane protein 3 -2.01883
IQSEC1 IQ motif and Sec7 domain 1 -2.0157
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 -2.00371
POGLUT1 protein O-glucosyltransferase 1 -2.0028
ACTA2 actin, alpha 2, smooth muscle, aorta -1.99991
TSHZ3 teashirt zinc finger homeobox 3 -1.99626
RPP21 ribonuclease P/MRP 21kDa subunit -1.99495
MCMBP minichromosome maintenance complex binding protein -1.9909
CTH cystathionine gamma-lyase -1.98757
SMAD6 SMAD family member 6 -1.98498
MTFMT mitochondrial methionyl-tRNA formyltransferase -1.98444
GEMIN7 gem (nuclear organelle) associated protein 7 -1.98415
TMEM160 transmembrane protein 160 -1.98412
GLIPR2 GLI pathogenesis-related 2 -1.98392
REEP5 receptor accessory protein 5 -1.98242
HIGD2A HIG1 hypoxia inducible domain family, member 2A -1.97837
NDUFA4 NDUFA4, mitochondrial complex associated -1.97295
ADGRG1 adhesion G protein-coupled receptor G1 -1.9647
MGST3 microsomal glutathione S-transferase 3 -1.96295
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 -1.96224
UTP6 UTP6, small subunit (SSU) processome component, homolog (yeast) -1.957
UGDH UDP-glucose 6-dehydrogenase -1.94829
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa -1.94796
SNHG3 small nucleolar RNA host gene 3 -1.94383
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 -1.93819
MSRB3 methionine sulfoxide reductase B3 -1.93667
PRRC2A proline-rich coiled-coil 2A -1.9352
GNG11 guanine nucleotide binding protein (G protein), gamma 11 -1.93138
XKR5 XK, Kell blood group complex subunit-related family, member 5 -1.93049
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase -1.92999
TMEM171 transmembrane protein 171 -1.92841
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa -1.91837
CISD2 CDGSH iron sulfur domain 2 -1.91543
CAMK2N2 calcium/calmodulin-dependent protein kinase II inhibitor 2 -1.91395
TSPAN32 tetraspanin 32 -1.91197
SHROOM2 shroom family member 2 -1.91084
MRPL34 mitochondrial ribosomal protein L34 -1.903
UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI -1.9016
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -1.89717
UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa -1.89488
CDK16 cyclin-dependent kinase 16 -1.89433
HSPB6 heat shock protein, alpha-crystallin-related, B6 -1.89296
COPE coatomer protein complex, subunit epsilon -1.88953
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 -1.88694
NUTF2 nuclear transport factor 2 -1.88057
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 -1.87755
TMEM56 transmembrane protein 56 -1.87741
PKD1 polycystic kidney disease 1 (autosomal dominant) -1.8738
RNF219 ring finger protein 219 -1.86623
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa -1.86485
FN1 fibronectin 1 -1.85459
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 -1.85346
HSPG2 heparan sulfate proteoglycan 2 -1.85271
RAMP2 receptor (G protein-coupled) activity modifying protein 2 -1.84715
VAMP8 vesicle-associated membrane protein 8 -1.84566
NFIC nuclear factor I/C (CCAAT-binding transcription factor) -1.8453
CDK13 cyclin-dependent kinase 13 -1.83832
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3 -1.83605
ATP5E ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit -1.82863
SEC61B Sec61 beta subunit -1.82756
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 -1.82595
CXCL12 chemokine (C-X-C motif) ligand 12 -1.8251
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -1.8244
TNRC6A trinucleotide repeat containing 6A -1.82437
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2 -1.82347
PTGDS prostaglandin D2 synthase 21kDa (brain) -1.82128
STIM2 stromal interaction molecule 2 -1.81863
CD151 CD151 molecule (Raph blood group) -1.81762
NPEPL1 aminopeptidase-like 1 -1.8165
TAOK1 TAO kinase 1 -1.81452
ATOX1 antioxidant 1 copper chaperone -1.80958
ARGLU1 arginine and glutamate rich 1 -1.80611
PI16 peptidase inhibitor 16 -1.80553
GPRC5A G protein-coupled receptor, class C, group 5, member A -1.80053
TRAF3 TNF receptor-associated factor 3 -1.79962
CDH13 cadherin 13 -1.79938
RAP1GAP2 RAP1 GTPase activating protein 2 -1.79524
TMEM147 transmembrane protein 147 -1.78706
EHD3 EH-domain containing 3 -1.78558
ANKRD10 ankyrin repeat domain 10 -1.7819
EMP3 epithelial membrane protein 3 -1.77901
CCDC59 coiled-coil domain containing 59 -1.77685
NDUFA12 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 -1.7742
PARK7 parkinson protein 7 -1.77259
ATXN1L ataxin 1-like -1.77179
MCAM melanoma cell adhesion molecule -1.7712
MPV17L2 MPV17 mitochondrial membrane protein-like 2 -1.76974
MRPL20 mitochondrial ribosomal protein L20 -1.76547
GAS6 growth arrest-specific 6 -1.76357
KIN Kin17 DNA and RNA binding protein -1.76329
KRT10 keratin 10, type I -1.76244
OSTC oligosaccharyltransferase complex subunit (non-catalytic) -1.7618
ABAT 4-aminobutyrate aminotransferase -1.75831
PURB purine-rich element binding protein B -1.75585
USP54 ubiquitin specific peptidase 54 -1.75506
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4 -1.75374
SNX18 sorting nexin 18 -1.75081
FIZ1 FLT3-interacting zinc finger 1 -1.74748
RUNDC3A RUN domain containing 3A -1.74605
GLI3 GLI family zinc finger 3 -1.74477
B3GALTL beta 1,3-galactosyltransferase-like -1.74415
MRPS6 mitochondrial ribosomal protein S6 -1.74402
ASB6 ankyrin repeat and SOCS box containing 6 -1.74374
VEZT vezatin, adherens junctions transmembrane protein -1.74167
S100A16 S100 calcium binding protein A16 -1.74143
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A -1.74019
GPR39 G protein-coupled receptor 39 -1.73023
KRTCAP2 keratinocyte associated protein 2 -1.73021
FAM65A family with sequence similarity 65, member A -1.72471
HINT2 histidine triad nucleotide binding protein 2 -1.72417
CHPF2 chondroitin polymerizing factor 2 -1.724
COMT catechol-O-methyltransferase -1.72378
MARK2 MAP/microtubule affinity-regulating kinase 2 -1.72337
IRGQ immunity-related GTPase family, Q -1.7228
PANX1 pannexin 1 -1.72163
SFXN3 sideroflexin 3 -1.71936
RNF125 ring finger protein 125, E3 ubiquitin protein ligase -1.71903
SPNS2 spinster homolog 2 (Drosophila) -1.71902
TCEB2 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) -1.7185
ECHDC2 enoyl CoA hydratase domain containing 2 -1.7182
CHURC1 churchill domain containing 1 -1.71639
RCN1 reticulocalbin 1, EF-hand calcium binding domain -1.71536
RPS21 ribosomal protein S21 -1.71423
NHSL2 NHS-like 2 -1.71261
RPS16 ribosomal protein S16 -1.71228
BASP1 brain abundant, membrane attached signal protein 1 -1.70873
CCND2 cyclin D2 -1.70736
DHRS4 dehydrogenase/reductase (SDR family) member 4 -1.70479
SMN1 survival of motor neuron 1, telomeric -1.70465
SH3RF1 SH3 domain containing ring finger 1 -1.70291
MAT2A methionine adenosyltransferase II, alpha -1.70071
TIMP3 TIMP metallopeptidase inhibitor 3 -1.70044
STK35 serine/threonine kinase 35 -1.69923
PITPNM2 phosphatidylinositol transfer protein, membrane-associated 2 -1.6974
TMEM165 transmembrane protein 165 -1.69412
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -1.69085
PDE4A phosphodiesterase 4A, cAMP-specific -1.69084
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa -1.68962
PLEKHG2 pleckstrin homology domain containing, family G (with RhoGef domain) member 2 -1.68182
ANKRD50 ankyrin repeat domain 50 -1.67837
C16ORF89 chromosome 16 open reading frame 89 -1.67692
CHCHD1 coiled-coil-helix-coiled-coil-helix domain containing 1 -1.67315
TIMP1 TIMP metallopeptidase inhibitor 1 -1.66935
ACP5 acid phosphatase 5, tartrate resistant -1.66205
FSCN1 fascin actin-bundling protein 1 -1.66185
CD3EAP CD3e molecule, epsilon associated protein -1.65943
MLEC malectin -1.65778
CLP1 cleavage and polyadenylation factor I subunit 1 -1.65743
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 -1.65721
BICD2 bicaudal D homolog 2 (Drosophila) -1.65641
WDR93 WD repeat domain 93 -1.65509
PCDH1 protocadherin 1 -1.65486
PHTF2 putative homeodomain transcription factor 2 -1.65413
NXT2 nuclear transport factor 2-like export factor 2 -1.64909
SLC25A44 solute carrier family 25, member 44 -1.64651
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide -1.64632
PRKCI protein kinase C, iota -1.64595
TMEM87A transmembrane protein 87A -1.64591
GRWD1 glutamate-rich WD repeat containing 1 -1.64549
TMEM50A transmembrane protein 50A -1.64491
MAZ MYC-associated zinc finger protein (purine-binding transcription factor) -1.64339
NGEF neuronal guanine nucleotide exchange factor -1.6416
CCDC137 coiled-coil domain containing 137 -1.64147
TMEM88 transmembrane protein 88 -1.6404
FBXW5 F-box and WD repeat domain containing 5 -1.63944
SUB1 SUB1 homolog (S. cerevisiae) -1.63853
HSPA12B heat shock 70kD protein 12B -1.63799
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase -1.63785
IGFBP4 insulin-like growth factor binding protein 4 -1.63405
TMEM205 transmembrane protein 205 -1.63354
ARL6IP6 ADP-ribosylation factor-like 6 interacting protein 6 -1.63075
BMPER BMP binding endothelial regulator -1.62943
DDHD2 DDHD domain containing 2 -1.62381
TMEM14C transmembrane protein 14C -1.62165
BOLA2 bolA family member 2 -1.62035
TMEM141 transmembrane protein 141 -1.61965
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 -1.61723
BST1 bone marrow stromal cell antigen 1 -1.61615
H2AFJ H2A histone family, member J -1.61602
PCBD2 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2 -1.6156
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 -1.61207
GAS2L1 growth arrest-specific 2 like 1 -1.61166
LRP10 low density lipoprotein receptor-related protein 10 -1.60977
TFIP11 tuftelin interacting protein 11 -1.60969
PHPT1 phosphohistidine phosphatase 1 -1.60718
SLC10A7 solute carrier family 10, member 7 -1.6068
KLHL21 kelch-like family member 21 -1.60641
HSPE1 heat shock 10kDa protein 1 -1.60523
KCNK6 potassium channel, two pore domain subfamily K, member 6 -1.60308
CDK14 cyclin-dependent kinase 14 -1.60289
C18ORF32 chromosome 18 open reading frame 32 -1.60008
TMEM150A transmembrane protein 150A -1.59864
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3 -1.59773
PPAPDC1B phosphatidic acid phosphatase type 2 domain containing 1B -1.59622
NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa -1.59622
SKIL SKI-like proto-oncogene -1.59605
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -1.59387
COX5A cytochrome c oxidase subunit Va -1.59318
EFNB2 ephrin-B2 -1.58923
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma -1.58639
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 -1.58634
RAB4A RAB4A, member RAS oncogene family -1.58389
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae) -1.57968
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa -1.57968
PPTC7 PTC7 protein phosphatase homolog (S. cerevisiae) -1.57614