ROGDI Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description rogdi homolog (Drosophila)|This gene encodes a protein of unknown function. Loss-of-function mutation in this gene cause Kohlschutter-Tonz syndrome. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012] (NCBI Entrez Gene Database, 79641)
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Genes

309 genes differentially expressed following the ROGDI gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
GJA3 gap junction protein, alpha 3, 46kDa 2.38113
LRRC55 leucine rich repeat containing 55 2.38113
TSPAN1 tetraspanin 1 2.38113
GJA10 gap junction protein, alpha 10, 62kDa 2.38113
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) 2.38113
GCKR glucokinase (hexokinase 4) regulator 2.38113
KLHL6 kelch-like family member 6 2.38113
HSPB6 heat shock protein, alpha-crystallin-related, B6 2.38113
IGFL3 IGF-like family member 3 2.38113
TACSTD2 tumor-associated calcium signal transducer 2 2.38113
TIGIT T cell immunoreceptor with Ig and ITIM domains 2.38113
ACSM4 acyl-CoA synthetase medium-chain family member 4 2.38113
GCSAM germinal center-associated, signaling and motility 2.38113
DSG1 desmoglein 1 2.38113
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 2.38113
EPO erythropoietin 2.38113
PTPN20 protein tyrosine phosphatase, non-receptor type 20 2.38113
CFAP157 cilia and flagella associated protein 157 2.38113
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13 2.38113
TDRD9 tudor domain containing 9 2.38113
DUSP29 dual specificity phosphatase 29 2.38113
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 2.38113
CPB2 carboxypeptidase B2 (plasma) 2.38113
GUCY2D guanylate cyclase 2D, membrane (retina-specific) 2.38113
PAGE4 P antigen family, member 4 (prostate associated) 2.38113
H1-6 H1.6 linker histone, cluster member 2.38113
CWF19L1 CWF19-like 1, cell cycle control (S. pombe) 2.35676
RIOX2 ribosomal oxygenase 2 2.32348
ALPK2 alpha-kinase 2 2.28944
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 2.28944
FMNL3 formin-like 3 2.28944
LRRD1 leucine-rich repeats and death domain containing 1 2.28944
SLC6A19 solute carrier family 6 (neutral amino acid transporter), member 19 2.28944
RAET1G retinoic acid early transcript 1G 2.28944
RNF17 ring finger protein 17 2.28944
TMEM212 transmembrane protein 212 2.28944
GJB4 gap junction protein, beta 4, 30.3kDa 2.28944
PCDHB1 protocadherin beta 1 2.28944
TUBE1 tubulin, epsilon 1 2.28944
USH1G Usher syndrome 1G (autosomal recessive) 2.28944
LCE1C late cornified envelope 1C 2.28944
PI16 peptidase inhibitor 16 2.28944
SCN2B sodium channel, voltage gated, type II beta subunit 2.28944
MTTP microsomal triglyceride transfer protein 2.28944
MUC5B mucin 5B, oligomeric mucus/gel-forming 2.28944
RSPO1 R-spondin 1 2.28944
EML2 echinoderm microtubule associated protein like 2 2.28944
SLC30A4 solute carrier family 30 (zinc transporter), member 4 2.28944
FRMD1 FERM domain containing 1 2.28944
ATXN2 ataxin 2 2.28944
RASA4B RAS p21 protein activator 4B 2.28944
TM4SF20 transmembrane 4 L six family member 20 2.28944
PGBDF plakoglobin binding and degradation factor 2.28944
MILR1 mast cell immunoglobulin-like receptor 1 2.28944
FOXA2 forkhead box A2 2.28944
GLUD2 glutamate dehydrogenase 2 2.28944
MAGEA2 melanoma antigen family A2 2.28944
CAPNS2 calpain, small subunit 2 2.28944
MFAP5 microfibrillar associated protein 5 2.28944
PAX8 paired box 8 2.28944
TBX22 T-box 22 2.28944
NOTCH2NLB notch 2 N-terminal like B 2.28944
OR6F1 olfactory receptor, family 6, subfamily F, member 1 2.28944
XKR3 XK, Kell blood group complex subunit-related family, member 3 2.28944
ZNF446 zinc finger protein 446 2.28944
OR52E5 olfactory receptor, family 52, subfamily E, member 5 2.28944
MAG myelin associated glycoprotein 2.28944
ARL14EPL ADP-ribosylation factor-like 14 effector protein-like 2.28944
KL klotho 2.28944
ACE2 angiotensin I converting enzyme 2 2.28944
FOXN4 forkhead box N4 2.28944
SPRR2F small proline-rich protein 2F 2.28944
TRPC5 transient receptor potential cation channel, subfamily C, member 5 2.28944
UBE2L5 ubiquitin conjugating enzyme E2 L5 2.28944
CGB3 chorionic gonadotropin subunit beta 3 2.28944
CCDC198 coiled-coil domain containing 198 2.28944
GASK1B golgi associated kinase 1B 2.28944
ZNF726 zinc finger protein 726 2.28944
ZAR1 zygote arrest 1 2.28944
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 2.28944
AANAT aralkylamine N-acetyltransferase 2.28944
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 2.28944
LRRC72 leucine rich repeat containing 72 2.28944
LRIT1 leucine-rich repeat, immunoglobulin-like and transmembrane domains 1 2.28944
CD79A CD79a molecule, immunoglobulin-associated alpha 2.28944
AXDND1 axonemal dynein light chain domain containing 1 2.28944
DAO D-amino-acid oxidase 2.28944
OR7C1 olfactory receptor, family 7, subfamily C, member 1 2.28944
NXPE1 neurexophilin and PC-esterase domain family, member 1 2.28944
PTPRH protein tyrosine phosphatase, receptor type, H 2.28944
FAM170A family with sequence similarity 170, member A 2.28944
DMBX1 diencephalon/mesencephalon homeobox 1 2.28944
TLR8 toll-like receptor 8 2.28944
GZMM granzyme M (lymphocyte met-ase 1) 2.28944
TARM1 T cell-interacting, activating receptor on myeloid cells 1 2.28944
VCX3A variable charge, X-linked 3A 2.28944
SASH3 SAM and SH3 domain containing 3 2.28944
CELA2A chymotrypsin-like elastase family, member 2A 2.28944
EXOC3L1 exocyst complex component 3-like 1 2.28944
GJD2 gap junction protein, delta 2, 36kDa 2.28944
MIP major intrinsic protein of lens fiber 2.28944
PGC progastricsin (pepsinogen C) 2.28944
DNMT3L DNA (cytosine-5-)-methyltransferase 3-like 2.28944
PPL periplakin 2.28944
LRRC43 leucine rich repeat containing 43 2.28944
NIM1K NIM1 serine/threonine protein kinase 2.28944
OXGR1 oxoglutarate (alpha-ketoglutarate) receptor 1 2.28944
RGSL1 regulator of G-protein signaling like 1 2.28944
AQP7 aquaporin 7 2.28944
HHATL hedgehog acyltransferase-like 2.28944
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 2.28944
GML glycosylphosphatidylinositol anchored molecule like 2.28944
FNDC1 fibronectin type III domain containing 1 2.28944
CABP7 calcium binding protein 7 2.28944
MBOAT4 membrane bound O-acyltransferase domain containing 4 2.28944
TRPM4 transient receptor potential cation channel, subfamily M, member 4 2.28944
CHRM4 cholinergic receptor, muscarinic 4 2.28944
ADGRF1 adhesion G protein-coupled receptor F1 2.28944
ANKRD33 ankyrin repeat domain 33 2.28944
TBC1D28 TBC1 domain family, member 28 2.28944
TBC1D26 TBC1 domain family, member 26 2.28944
FIGLA folliculogenesis specific basic helix-loop-helix 2.28944
FCN3 ficolin (collagen/fibrinogen domain containing) 3 2.28944
TDRD10 tudor domain containing 10 2.28944
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12 2.28944
SMIM17 small integral membrane protein 17 2.28944
SIGLEC11 sialic acid binding Ig-like lectin 11 2.28944
POGZ pogo transposable element with ZNF domain 2.28944
GPR62 G protein-coupled receptor 62 2.28944
CD28 CD28 molecule 2.28944
OSR1 odd-skipped related transciption factor 1 2.28944
CXORF58 chromosome X open reading frame 58 2.28944
CCDC70 coiled-coil domain containing 70 2.28944
RRM1 ribonucleotide reductase M1 2.28944
TF transferrin 2.28944
ITGB6 integrin, beta 6 2.28944
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) 2.28944
CFB complement factor B 2.28944
GOLGA8N golgin A8 family, member N 2.28944
PPP1R14C protein phosphatase 1, regulatory (inhibitor) subunit 14C 2.28944
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 2.28944
P2RX6 purinergic receptor P2X, ligand gated ion channel, 6 2.28944
KLK2 kallikrein-related peptidase 2 2.28944
FGG fibrinogen gamma chain 2.28944
SFTA2 surfactant associated 2 2.28944
ANKRD1 ankyrin repeat domain 1 (cardiac muscle) 2.28944
DUOXA1 dual oxidase maturation factor 1 2.28944
GCSAML germinal center-associated, signaling and motility-like 2.28944
FOXG1 forkhead box G1 2.28944
LUZP2 leucine zipper protein 2 2.28944
SPAG8 sperm associated antigen 8 2.28944
ANKRD30A ankyrin repeat domain 30A 2.28944
RNASE6 ribonuclease, RNase A family, k6 2.28944
AREG amphiregulin 2.28944
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 2.28944
ZC2HC1B zinc finger, C2HC-type containing 1B 2.28944
NR4A3 nuclear receptor subfamily 4, group A, member 3 2.28944
KRTAP13-4 keratin associated protein 13-4 2.28944
TPRX1 tetra-peptide repeat homeobox 1 2.28944
HRG histidine-rich glycoprotein 2.28944
METTL21C methyltransferase like 21C 2.28944
TNMD tenomodulin 2.28944
SP9 Sp9 transcription factor 2.28944
TAS2R43 taste receptor, type 2, member 43 2.28944
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2 2.28944
TMPRSS12 transmembrane (C-terminal) protease, serine 12 2.28944
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 2.28944
GNRH2 gonadotropin-releasing hormone 2 2.28944
GRIK2 glutamate receptor, ionotropic, kainate 2 2.28944
IL10RA interleukin 10 receptor, alpha 2.28944
TAS2R19 taste receptor, type 2, member 19 2.28944
PPP1R3A protein phosphatase 1, regulatory subunit 3A 2.28944
BMP3 bone morphogenetic protein 3 2.28944
C21ORF140 chromosome 21 open reading frame 140 2.28944
TGM3 transglutaminase 3 2.28944
TEN1 TEN1 CST complex subunit 2.28449
CD59 CD59 molecule, complement regulatory protein 2.28449
MVB12B multivesicular body subunit 12B 2.2576
KLHL24 kelch-like family member 24 2.22481
WDR31 WD repeat domain 31 2.2128
TCEA1 transcription elongation factor A (SII), 1 2.2128
FMN2 formin 2 2.18658
LOC730098 uncharacterized LOC730098 2.17966
LTBP2 latent transforming growth factor beta binding protein 2 2.17866
ACSM3 acyl-CoA synthetase medium-chain family member 3 2.17654
C1GALT1C1 C1GALT1-specific chaperone 1 2.16043
PLEKHA3 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3 2.16043
ZCCHC2 zinc finger, CCHC domain containing 2 2.14326
STRN4 striatin, calmodulin binding protein 4 2.13666
RIMS4 regulating synaptic membrane exocytosis 4 2.13666
CHIC2 cysteine-rich hydrophobic domain 2 2.13117
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 2.11907
CLDN19 claudin 19 2.0875
PLPP1 phospholipid phosphatase 1 2.08505
SEMA6C sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C 2.08329
SUMF2 sulfatase modifying factor 2 2.07966
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa 2.07617
TGOLN2 trans-golgi network protein 2 2.07077
DGKI diacylglycerol kinase, iota 2.06379
MSMO1 methylsterol monooxygenase 1 2.05568
PPIA peptidylprolyl isomerase A (cyclophilin A) 2.05317
ZNF484 zinc finger protein 484 2.03966
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase 2.03054
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2 2.02884
MGAT5B mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B 2.02496
ZNF516 zinc finger protein 516 2.02428
CRYBG3 beta-gamma crystallin domain containing 3 2.00786
PET100 PET100 homolog (S. cerevisiae) 2.00786
UBC ubiquitin C 2.00786
PTCD3 pentatricopeptide repeat domain 3 2.00509
RWDD4 RWD domain containing 4 2.00006

decreased expression

Symbol Name Standardized Value
TSGA10IP testis specific, 10 interacting protein -2.38113
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -2.38113
AP5S1 adaptor-related protein complex 5, sigma 1 subunit -2.38113
LPAR6 lysophosphatidic acid receptor 6 -2.38113
SLC30A10 solute carrier family 30, member 10 -2.38113
TBX10 T-box 10 -2.38113
PLA2G2C phospholipase A2, group IIC -2.38113
OR14A16 olfactory receptor, family 14, subfamily A, member 16 -2.38113
SLCO1A2 solute carrier organic anion transporter family, member 1A2 -2.29317
ZNF324 zinc finger protein 324 -2.28944
RGPD3 RANBP2-like and GRIP domain containing 3 -2.28944
AK7 adenylate kinase 7 -2.28944
TPPP tubulin polymerization promoting protein -2.28944
RNF39 ring finger protein 39 -2.28944
TENM4 teneurin transmembrane protein 4 -2.28944
RNF222 ring finger protein 222 -2.28944
SPINT4 serine peptidase inhibitor, Kunitz type 4 -2.28944
NRG4 neuregulin 4 -2.28944
PLCZ1 phospholipase C, zeta 1 -2.28944
TMEM217 transmembrane protein 217 -2.28944
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) -2.28944
ATP13A4 ATPase type 13A4 -2.28944
ATP13A1 ATPase type 13A1 -2.28944
P2RY8 purinergic receptor P2Y, G-protein coupled, 8 -2.28944
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z -2.28944
ODAD4 outer dynein arm docking complex subunit 4 -2.28944
CCDC97 coiled-coil domain containing 97 -2.28944
RNF214 ring finger protein 214 -2.28944
MRPL2 mitochondrial ribosomal protein L2 -2.28944
PLAGL2 pleiomorphic adenoma gene-like 2 -2.28944
A2M alpha-2-macroglobulin -2.28944
TRPC3 transient receptor potential cation channel, subfamily C, member 3 -2.28944
CCDC121 coiled-coil domain containing 121 -2.28944
NEU3 sialidase 3 (membrane sialidase) -2.28944
CSF1 colony stimulating factor 1 (macrophage) -2.28944
RGPD6 RANBP2-like and GRIP domain containing 6 -2.28944
ZFYVE19 zinc finger, FYVE domain containing 19 -2.28944
ART1 ADP-ribosyltransferase 1 -2.28944
RRH retinal pigment epithelium-derived rhodopsin homolog -2.28944
HAGH hydroxyacylglutathione hydrolase -2.28944
EPHA10 EPH receptor A10 -2.28944
CRYBA4 crystallin, beta A4 -2.28944
FOXP4 forkhead box P4 -2.28944
CLEC4A C-type lectin domain family 4, member A -2.28944
TCAP titin-cap -2.28944
ORM2 orosomucoid 2 -2.28944
CBLIF cobalamin binding intrinsic factor -2.28944
DLEC1 deleted in lung and esophageal cancer 1 -2.28944
ART4 ADP-ribosyltransferase 4 (Dombrock blood group) -2.28944
SOD2 superoxide dismutase 2, mitochondrial -2.28944
KY kyphoscoliosis peptidase -2.28944
ANKRD30BL ankyrin repeat domain 30B-like -2.28944
CYSLTR1 cysteinyl leukotriene receptor 1 -2.28944
TMEM45A transmembrane protein 45A -2.28944
AK8 adenylate kinase 8 -2.28944
MELTF melanotransferrin -2.28944
IFNE interferon, epsilon -2.28944
SQOR sulfide quinone oxidoreductase -2.28944
FZD1 frizzled class receptor 1 -2.28944
PPP1R3G protein phosphatase 1, regulatory subunit 3G -2.28944
SEZ6L2 seizure related 6 homolog (mouse)-like 2 -2.28944
TRIM72 tripartite motif containing 72, E3 ubiquitin protein ligase -2.26524
HES4 hes family bHLH transcription factor 4 -2.26524
BICC1 BicC family RNA binding protein 1 -2.23372
ACSBG1 acyl-CoA synthetase bubblegum family member 1 -2.23322
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -2.22795
LIMCH1 LIM and calponin homology domains 1 -2.22754
VMP1 vacuole membrane protein 1 -2.20725
UBE2O ubiquitin-conjugating enzyme E2O -2.1968
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 -2.1968
EPSTI1 epithelial stromal interaction 1 (breast) -2.1968
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -2.17866
NUP160 nucleoporin 160kDa -2.17654
TCL1A T-cell leukemia/lymphoma 1A -2.16559
PAK1IP1 PAK1 interacting protein 1 -2.13794
MRPL57 mitochondrial ribosomal protein L57 -2.13117
SYT13 synaptotagmin XIII -2.10934
MARCHF7 membrane associated ring-CH-type finger 7 -2.0989
DOCK6 dedicator of cytokinesis 6 -2.09338
ZFP2 ZFP2 zinc finger protein -2.08329
SPA17 sperm autoantigenic protein 17 -2.08329
ZMIZ1 zinc finger, MIZ-type containing 1 -2.08329
ZNF582 zinc finger protein 582 -2.07966
SHISA7 shisa family member 7 -2.07966
CA11 carbonic anhydrase XI -2.07737
UTRN utrophin -2.07617
OFD1 oral-facial-digital syndrome 1 -2.065
NANOS1 nanos homolog 1 (Drosophila) -2.06379
CRYL1 crystallin, lambda 1 -2.05891
LPL lipoprotein lipase -2.05181
NAT9 N-acetyltransferase 9 (GCN5-related, putative) -2.04974
GPR155 G protein-coupled receptor 155 -2.02331
SMIM20 small integral membrane protein 20 -2.01804
CNBD2 cyclic nucleotide binding domain containing 2 -2.01143
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) -2.00509
ELFN1 extracellular leucine-rich repeat and fibronectin type III domain containing 1 -2.00126
PTAFR platelet-activating factor receptor -2.00126
YTHDC2 YTH domain containing 2 -2.00126