| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | receptor tyrosine kinase-like orphan receptor 1|This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2012] (NCBI Entrez Gene Database, 4919) |
| External Link | https://ncbi.nlm.nih.gov/gene/4919 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the ROR1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CPVL | carboxypeptidase, vitellogenic-like | 0.0147154 |
| TXNDC9 | thioredoxin domain containing 9 | 0.0144598 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.0125952 |
| PHACTR2 | phosphatase and actin regulator 2 | 0.0113468 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.0105689 |
| GCH1 | GTP cyclohydrolase 1 | 0.00985153 |
| THBS1 | thrombospondin 1 | 0.00959145 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | 0.009547 |
| PDGFC | platelet derived growth factor C | 0.009342 |
| HAL | histidine ammonia-lyase | 0.00910662 |
| LYZ | lysozyme | 0.00893366 |
| CDC20 | cell division cycle 20 | 0.00885714 |
| PRDX2 | peroxiredoxin 2 | 0.0085836 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00847133 |
| CCNA2 | cyclin A2 | 0.00826176 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | 0.00825853 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | 0.00824579 |
| TXNIP | thioredoxin interacting protein | 0.0082391 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.00806867 |
| PEG3 | paternally expressed 3 | 0.00804645 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | 0.00789161 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.00788612 |
| DPYD | dihydropyrimidine dehydrogenase | 0.00787378 |
| TMEM45A | transmembrane protein 45A | 0.00781466 |
| ARMT1 | acidic residue methyltransferase 1 | 0.0077966 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 0.00779355 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | 0.00775391 |
| COL4A5 | collagen, type IV, alpha 5 | 0.00760747 |
| METTL7A | methyltransferase like 7A | 0.00753141 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.00748466 |
| MAP7 | microtubule-associated protein 7 | 0.00743952 |
| DDHD2 | DDHD domain containing 2 | 0.00737467 |
| BEX1 | brain expressed, X-linked 1 | 0.00734122 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 0.00732933 |
| STK10 | serine/threonine kinase 10 | 0.00727274 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | 0.00716997 |
| CADM1 | cell adhesion molecule 1 | 0.00715861 |
| FGL2 | fibrinogen-like 2 | 0.00708924 |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 | 0.00706246 |
| FAM162A | family with sequence similarity 162, member A | 0.00698193 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | 0.00693517 |
| SRP9 | signal recognition particle 9kDa | 0.0069332 |
| KIAA0100 | KIAA0100 | 0.00692211 |
| SFRP1 | secreted frizzled-related protein 1 | 0.00688032 |
| GUCY2C | guanylate cyclase 2C | 0.00687063 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.00681718 |
| CDCA4 | cell division cycle associated 4 | 0.00681289 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.00679406 |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta | 0.00676974 |
| CLU | clusterin | 0.00676771 |
| FZD5 | frizzled class receptor 5 | 0.00675762 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like | 0.00670211 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.00669511 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.00667402 |
| SEPHS1 | selenophosphate synthetase 1 | 0.00664821 |
| TBC1D9B | TBC1 domain family, member 9B (with GRAM domain) | 0.00664745 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | 0.00664711 |
| SLC39A6 | solute carrier family 39 (zinc transporter), member 6 | 0.00663756 |
| ERLIN2 | ER lipid raft associated 2 | 0.00656771 |
| TDO2 | tryptophan 2,3-dioxygenase | 0.0064889 |
| ATP6V1B2 | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 | 0.00646302 |
| DHCR24 | 24-dehydrocholesterol reductase | 0.00644839 |
| RAB38 | RAB38, member RAS oncogene family | 0.00643945 |
| ISOC1 | isochorismatase domain containing 1 | 0.00638266 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | 0.00637627 |
| C2CD5 | C2 calcium-dependent domain containing 5 | 0.00636885 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | 0.0063677 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 0.00632552 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | 0.00630616 |
| TLK1 | tousled-like kinase 1 | 0.00630102 |
| FOXN3 | forkhead box N3 | 0.00628105 |
| ADAMDEC1 | ADAM-like, decysin 1 | 0.00627028 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 0.00621728 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.00618287 |
| CHN2 | chimerin 2 | 0.00618215 |
| SHTN1 | shootin 1 | 0.00613393 |
| INSIG1 | insulin induced gene 1 | 0.00610869 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | 0.00609685 |
| VRK1 | vaccinia related kinase 1 | 0.00608401 |
| ELP1 | elongator acetyltransferase complex subunit 1 | 0.00604731 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | 0.00603117 |
| GAMT | guanidinoacetate N-methyltransferase | 0.00600762 |
| ADAM28 | ADAM metallopeptidase domain 28 | 0.00599562 |
| AIF1 | allograft inflammatory factor 1 | 0.00599439 |
| UBE2N | ubiquitin-conjugating enzyme E2N | 0.00597875 |
| LRRC40 | leucine rich repeat containing 40 | 0.00592162 |
| SFRP4 | secreted frizzled-related protein 4 | 0.00591258 |
| SUB1 | SUB1 homolog (S. cerevisiae) | 0.00589347 |
| FAM3C | family with sequence similarity 3, member C | 0.00586355 |
| ANKRD46 | ankyrin repeat domain 46 | 0.00585779 |
| CAPN7 | calpain 7 | 0.00584795 |
| DSE | dermatan sulfate epimerase | 0.00584775 |
| TMX1 | thioredoxin-related transmembrane protein 1 | 0.00583798 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.00583237 |
| DUT | deoxyuridine triphosphatase | 0.00582463 |
| PLAGL1 | pleiomorphic adenoma gene-like 1 | 0.00580089 |
| PLXNC1 | plexin C1 | 0.00579077 |
| CD8A | CD8a molecule | 0.00576024 |
| RNF138 | ring finger protein 138, E3 ubiquitin protein ligase | 0.00575213 |
| L1TD1 | LINE-1 type transposase domain containing 1 | 0.00574905 |
| PPP3CB | protein phosphatase 3, catalytic subunit, beta isozyme | 0.00573975 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | 0.00572386 |
| TNFSF13B | tumor necrosis factor (ligand) superfamily, member 13b | 0.00568598 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 | 0.00568409 |
| RAB2A | RAB2A, member RAS oncogene family | 0.00567811 |
| PAXIP1 | PAX interacting (with transcription-activation domain) protein 1 | 0.00567802 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit | 0.00566575 |
| CD2 | CD2 molecule | 0.0056551 |
| CD4 | CD4 molecule | 0.00564705 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | 0.00564021 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.00563933 |
| DICER1 | dicer 1, ribonuclease type III | 0.00563029 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.00562899 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.00562336 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.00561975 |
| NPM3 | nucleophosmin/nucleoplasmin 3 | 0.00559286 |
| RMI1 | RecQ mediated genome instability 1 | 0.00559248 |
| GET1 | guided entry of tail-anchored proteins factor 1 | 0.00558985 |
| NFASC | neurofascin | 0.00556951 |
| TMEM131 | transmembrane protein 131 | 0.00555814 |
| SRPK2 | SRSF protein kinase 2 | 0.00554638 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.00553705 |
| FAM120A | family with sequence similarity 120A | 0.00552887 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.00552451 |
| FBN1 | fibrillin 1 | 0.00551272 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) | 0.00548826 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | 0.00546844 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.00546167 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | 0.00545756 |
| WASHC4 | WASH complex subunit 4 | 0.00545222 |
| CCR2 | chemokine (C-C motif) receptor 2 | 0.00543365 |
| LEPROTL1 | leptin receptor overlapping transcript-like 1 | 0.00542073 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0054056 |
| PANK3 | pantothenate kinase 3 | 0.00540271 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.00540199 |
| THOC7 | THO complex 7 | 0.00539954 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | 0.00536303 |
| H1-0 | H1.0 linker histone | 0.00535986 |
| SPTSSA | serine palmitoyltransferase, small subunit A | 0.00534694 |
| HMGB3 | high mobility group box 3 | 0.00531265 |
| CD164 | CD164 molecule, sialomucin | 0.00530826 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 0.00529175 |
| LRRC8D | leucine rich repeat containing 8 family, member D | 0.0052886 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa | 0.00528189 |
| TRAPPC8 | trafficking protein particle complex 8 | 0.00528174 |
| INSM1 | insulinoma-associated 1 | 0.0052692 |
| SATB2 | SATB homeobox 2 | 0.0052635 |
| TRIM13 | tripartite motif containing 13 | 0.00526188 |
| SCARB2 | scavenger receptor class B, member 2 | 0.00524762 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00523724 |
| OIP5 | Opa interacting protein 5 | 0.00523663 |
| RAPSN | receptor-associated protein of the synapse | 0.00523557 |
| ATP13A3 | ATPase type 13A3 | 0.00523487 |
| SSX2IP | synovial sarcoma, X breakpoint 2 interacting protein | 0.00523378 |
| SOCS5 | suppressor of cytokine signaling 5 | 0.00522308 |
| CREB1 | cAMP responsive element binding protein 1 | 0.00520772 |
| PURA | purine-rich element binding protein A | 0.00520619 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.00519308 |
| ARL5A | ADP-ribosylation factor-like 5A | 0.00517713 |
| NREP | neuronal regeneration related protein | 0.00516806 |
| CCDC47 | coiled-coil domain containing 47 | 0.00516779 |
| STAU2 | staufen double-stranded RNA binding protein 2 | 0.00515616 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A | 0.00515522 |
| SLC38A1 | solute carrier family 38, member 1 | 0.00515194 |
| XPO7 | exportin 7 | 0.0051483 |
| SCG5 | secretogranin V | 0.00514738 |
| ATF1 | activating transcription factor 1 | 0.00514051 |
| TRAPPC10 | trafficking protein particle complex 10 | 0.0051336 |
| PRDX3 | peroxiredoxin 3 | 0.00512617 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.0051224 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.00512203 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 0.00512063 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | 0.00509317 |
| RNF38 | ring finger protein 38 | 0.00508042 |
| PHTF2 | putative homeodomain transcription factor 2 | 0.00507662 |
| CEP350 | centrosomal protein 350kDa | 0.00507119 |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) | 0.00506503 |
| ITK | IL2-inducible T-cell kinase | 0.00505699 |
| EPHB2 | EPH receptor B2 | 0.0050567 |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H | 0.00505115 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.00503588 |
| DNASE1L3 | deoxyribonuclease I-like 3 | 0.00503345 |
| KIF1B | kinesin family member 1B | 0.00503333 |
| ACAT1 | acetyl-CoA acetyltransferase 1 | 0.00502 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.00501826 |
| NCKIPSD | NCK interacting protein with SH3 domain | 0.00501501 |
| GLS | glutaminase | 0.00500508 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.00500346 |
| HAT1 | histone acetyltransferase 1 | 0.00499914 |
| ATP11B | ATPase, class VI, type 11B | 0.00499514 |
| TPD52 | tumor protein D52 | 0.00499513 |
| CCNE2 | cyclin E2 | 0.0049942 |
| PRKCB | protein kinase C, beta | 0.0049778 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | 0.0049746 |
| EPB41L4B | erythrocyte membrane protein band 4.1 like 4B | 0.00497278 |
| FUCA1 | fucosidase, alpha-L- 1, tissue | 0.00496786 |
| LUM | lumican | 0.00496657 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.00496126 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.00495841 |
| SDC1 | syndecan 1 | 0.00493676 |
| RESF1 | retroelement silencing factor 1 | 0.00493184 |
| LST1 | leukocyte specific transcript 1 | 0.0049277 |
| USP1 | ubiquitin specific peptidase 1 | 0.00492366 |
| SMCO4 | single-pass membrane protein with coiled-coil domains 4 | 0.00491872 |
| SNX4 | sorting nexin 4 | 0.0049055 |
| ASF1A | anti-silencing function 1A histone chaperone | 0.00490231 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | 0.00489989 |
| NDFIP1 | Nedd4 family interacting protein 1 | 0.00489259 |
| VLDLR | very low density lipoprotein receptor | 0.00488183 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | 0.00488002 |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | 0.00487033 |
| TNS3 | tensin 3 | 0.00486981 |
| CNOT7 | CCR4-NOT transcription complex, subunit 7 | 0.00486869 |
| KYAT3 | kynurenine aminotransferase 3 | 0.00486021 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.00485975 |
| TMEM165 | transmembrane protein 165 | 0.00485778 |
| BICD2 | bicaudal D homolog 2 (Drosophila) | 0.00485695 |
| NUP133 | nucleoporin 133kDa | 0.00484463 |
| VDAC3 | voltage-dependent anion channel 3 | 0.00482619 |
| PMS1 | PMS1 postmeiotic segregation increased 1 (S. cerevisiae) | 0.00482499 |
| CPD | carboxypeptidase D | 0.00482171 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous | 0.00482072 |
| ATP8B4 | ATPase, class I, type 8B, member 4 | 0.0048119 |
| UTRN | utrophin | 0.00479992 |
| SEC24A | SEC24 family member A | 0.00479351 |
| RAB11A | RAB11A, member RAS oncogene family | 0.00478964 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.00477539 |
| REV1 | REV1, polymerase (DNA directed) | 0.00477447 |
| PSRC1 | proline/serine-rich coiled-coil 1 | 0.00476779 |
| RIDA | reactive intermediate imine deaminase A homolog | 0.00476578 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa | 0.00476439 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.00476417 |
| PIK3CB | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta | 0.0047637 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 | 0.00476278 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.0047589 |
| FASN | fatty acid synthase | 0.00475443 |
| RGS10 | regulator of G-protein signaling 10 | 0.00475196 |
| TM7SF2 | transmembrane 7 superfamily member 2 | 0.0047386 |
| NANOG | Nanog homeobox | 0.00472623 |
| GLCE | glucuronic acid epimerase | 0.00472317 |
| TEX30 | testis expressed 30 | 0.00469877 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0046966 |
| KCNK3 | potassium channel, two pore domain subfamily K, member 3 | 0.00467852 |
| ARHGEF9 | Cdc42 guanine nucleotide exchange factor (GEF) 9 | 0.00467276 |
| GCA | grancalcin, EF-hand calcium binding protein | 0.00466789 |
| IL32 | interleukin 32 | 0.00465145 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | 0.0046411 |
| ALB | albumin | 0.00462437 |
| PRR7 | proline rich 7 (synaptic) | 0.00462088 |
| NFYB | nuclear transcription factor Y, beta | 0.00461382 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA1A | heat shock 70kDa protein 1A | -0.0208418 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0151554 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.014344 |
| KLK11 | kallikrein-related peptidase 11 | -0.0131825 |
| AREG | amphiregulin | -0.0121226 |
| KLK10 | kallikrein-related peptidase 10 | -0.0118988 |
| HSPB8 | heat shock 22kDa protein 8 | -0.0117064 |
| ADIRF | adipogenesis regulatory factor | -0.0116864 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | -0.0115132 |
| EMP1 | epithelial membrane protein 1 | -0.0115003 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -0.0114699 |
| AGR2 | anterior gradient 2 | -0.0113923 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0112383 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0112065 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.011101 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0107698 |
| FXYD5 | FXYD domain containing ion transport regulator 5 | -0.0105833 |
| TPM2 | tropomyosin 2 (beta) | -0.0105751 |
| KRT19 | keratin 19, type I | -0.0105738 |
| RGCC | regulator of cell cycle | -0.0104518 |
| PDLIM4 | PDZ and LIM domain 4 | -0.0101565 |
| S100A10 | S100 calcium binding protein A10 | -0.0101397 |
| MALL | mal, T-cell differentiation protein-like | -0.00994235 |
| CRYAB | crystallin, alpha B | -0.00988157 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.00978767 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0096831 |
| YBX3 | Y box binding protein 3 | -0.00967294 |
| SYNM | synemin, intermediate filament protein | -0.00964251 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.00961568 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.00961016 |
| HEATR1 | HEAT repeat containing 1 | -0.00954789 |
| GPX3 | glutathione peroxidase 3 | -0.00950277 |
| ATF4 | activating transcription factor 4 | -0.00945919 |
| MMP7 | matrix metallopeptidase 7 | -0.00931491 |
| FOLR1 | folate receptor 1 (adult) | -0.00914449 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | -0.00903867 |
| ATF3 | activating transcription factor 3 | -0.00888222 |
| BHLHE41 | basic helix-loop-helix family, member e41 | -0.00880965 |
| KRT14 | keratin 14, type I | -0.00880909 |
| DERA | deoxyribose-phosphate aldolase (putative) | -0.00879743 |
| S100A11 | S100 calcium binding protein A11 | -0.00877649 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.00868102 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -0.008612 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | -0.00858851 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.00856631 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.00853384 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | -0.00851669 |
| TSPAN8 | tetraspanin 8 | -0.00845467 |
| GSTP1 | glutathione S-transferase pi 1 | -0.00844484 |
| PUF60 | poly-U binding splicing factor 60KDa | -0.00843596 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.0084195 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | -0.00841782 |
| KRT13 | keratin 13, type I | -0.00836533 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.00835179 |
| STC2 | stanniocalcin 2 | -0.00830439 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.00829228 |
| LTF | lactotransferrin | -0.00824391 |
| ATP9A | ATPase, class II, type 9A | -0.0081958 |
| PRAME | preferentially expressed antigen in melanoma | -0.00818275 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.00817799 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | -0.00816724 |
| PTN | pleiotrophin | -0.00816365 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | -0.00815586 |
| COLEC12 | collectin sub-family member 12 | -0.00804116 |
| VWF | von Willebrand factor | -0.00804078 |
| SRPX | sushi-repeat containing protein, X-linked | -0.00803217 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.00802385 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | -0.00800879 |
| KRT15 | keratin 15, type I | -0.00799792 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.00789859 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.00789796 |
| IRS2 | insulin receptor substrate 2 | -0.00789689 |
| KRT7 | keratin 7, type II | -0.00789155 |
| HMOX1 | heme oxygenase 1 | -0.00788822 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.0077971 |
| ASS1 | argininosuccinate synthase 1 | -0.0077754 |
| RGS5 | regulator of G-protein signaling 5 | -0.00774265 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.00772077 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon | -0.00765813 |
| SRPX2 | sushi-repeat containing protein, X-linked 2 | -0.00764559 |
| KLK6 | kallikrein-related peptidase 6 | -0.00760614 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | -0.0075976 |
| ANXA2P2 | annexin A2 pseudogene 2 | -0.0075493 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.00754286 |
| JUP | junction plakoglobin | -0.00751297 |
| TUFM | Tu translation elongation factor, mitochondrial | -0.00750125 |
| SQSTM1 | sequestosome 1 | -0.00746957 |
| MET | MET proto-oncogene, receptor tyrosine kinase | -0.00746573 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | -0.00745229 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | -0.00740188 |
| PFKP | phosphofructokinase, platelet | -0.00739917 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.00739624 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.00734118 |
| KRT5 | keratin 5, type II | -0.00731524 |
| ANXA11 | annexin A11 | -0.00731158 |
| BTG3 | BTG family, member 3 | -0.0073055 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.00729733 |
| RGS2 | regulator of G-protein signaling 2 | -0.00728629 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.00726906 |
| SELE | selectin E | -0.00725181 |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) | -0.00724877 |
| TIMP4 | TIMP metallopeptidase inhibitor 4 | -0.00721842 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 | -0.00720336 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.00719584 |
| NOTCH3 | notch 3 | -0.00717743 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | -0.00717619 |
| QPCT | glutaminyl-peptide cyclotransferase | -0.00716703 |
| DOK5 | docking protein 5 | -0.00716369 |
| NRCAM | neuronal cell adhesion molecule | -0.00716291 |
| FAM107A | family with sequence similarity 107, member A | -0.00713981 |
| IGFBP6 | insulin-like growth factor binding protein 6 | -0.00712253 |
| LAMB3 | laminin, beta 3 | -0.00711891 |
| UTP14A | UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) | -0.00709523 |
| KLF2 | Kruppel-like factor 2 | -0.00708258 |
| BCL3 | B-cell CLL/lymphoma 3 | -0.00706299 |
| MVP | major vault protein | -0.0070535 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.00704951 |
| EFNA1 | ephrin-A1 | -0.00703438 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | -0.00696502 |
| CD34 | CD34 molecule | -0.00694683 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.00693429 |
| G0S2 | G0/G1 switch 2 | -0.00692081 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | -0.00689833 |
| KLHL24 | kelch-like family member 24 | -0.0068933 |
| S100P | S100 calcium binding protein P | -0.0068857 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.00688214 |
| CSRP2 | cysteine and glycine-rich protein 2 | -0.00685547 |
| TSPO | translocator protein (18kDa) | -0.00683095 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -0.00681615 |
| PROM1 | prominin 1 | -0.00677867 |
| PMP22 | peripheral myelin protein 22 | -0.00677165 |
| TRAF3IP2 | TRAF3 interacting protein 2 | -0.00676119 |
| JUNB | jun B proto-oncogene | -0.00673809 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.00673403 |
| MMP3 | matrix metallopeptidase 3 | -0.00671989 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.00669028 |
| TBX2 | T-box 2 | -0.00668131 |
| CDC42SE1 | CDC42 small effector 1 | -0.0066575 |
| ACLY | ATP citrate lyase | -0.00665698 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.00664569 |
| KLK5 | kallikrein-related peptidase 5 | -0.00664539 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.00660042 |
| PRSS21 | protease, serine, 21 (testisin) | -0.00655942 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | -0.00655741 |
| MCAM | melanoma cell adhesion molecule | -0.00655684 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.00654613 |
| ADM | adrenomedullin | -0.00653558 |
| BAALC | brain and acute leukemia, cytoplasmic | -0.00652067 |
| INHBB | inhibin, beta B | -0.00650214 |
| LCN2 | lipocalin 2 | -0.00649925 |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) | -0.00645968 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00644705 |
| PRDX1 | peroxiredoxin 1 | -0.0064226 |
| HOXB7 | homeobox B7 | -0.00639391 |
| MEF2C | myocyte enhancer factor 2C | -0.00638253 |
| TP53I3 | tumor protein p53 inducible protein 3 | -0.00636672 |
| ARMCX6 | armadillo repeat containing, X-linked 6 | -0.00635552 |
| NES | nestin | -0.00635456 |
| TM4SF20 | transmembrane 4 L six family member 20 | -0.0063342 |
| LSR | lipolysis stimulated lipoprotein receptor | -0.00632757 |
| PLXND1 | plexin D1 | -0.0063195 |
| CLTB | clathrin, light chain B | -0.00631033 |
| TMSB15A | thymosin beta 15a | -0.00630263 |
| KRT17 | keratin 17, type I | -0.00629653 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.00628795 |
| STX4 | syntaxin 4 | -0.00627518 |
| C5AR1 | complement component 5a receptor 1 | -0.00626939 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | -0.00624977 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | -0.00624136 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.00624045 |
| TAF10 | TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa | -0.0062364 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | -0.00623267 |
| TBX3 | T-box 3 | -0.00623072 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.00620465 |
| GDF15 | growth differentiation factor 15 | -0.00619942 |
| ADGRL4 | adhesion G protein-coupled receptor L4 | -0.00619374 |
| STC1 | stanniocalcin 1 | -0.0061712 |
| PCOLCE | procollagen C-endopeptidase enhancer | -0.00616434 |
| CYB5A | cytochrome b5 type A (microsomal) | -0.00616298 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.00616217 |
| CRABP1 | cellular retinoic acid binding protein 1 | -0.00615922 |
| TMEM243 | transmembrane protein 243, mitochondrial | -0.00615138 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 | -0.00615086 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.00614623 |
| KRT16 | keratin 16, type I | -0.00614297 |
| KLK7 | kallikrein-related peptidase 7 | -0.00612609 |
| PRPF4 | pre-mRNA processing factor 4 | -0.00610688 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | -0.00609568 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | -0.00608795 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | -0.00608125 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.00605165 |
| CLDN5 | claudin 5 | -0.00604758 |
| LMCD1 | LIM and cysteine-rich domains 1 | -0.00604011 |
| HMGA1 | high mobility group AT-hook 1 | -0.00603405 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | -0.00603289 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0060289 |
| CDH5 | cadherin 5, type 2 (vascular endothelium) | -0.00602858 |
| MME | membrane metallo-endopeptidase | -0.00600058 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | -0.00598834 |
| TFF1 | trefoil factor 1 | -0.00594982 |
| ANXA2 | annexin A2 | -0.00594302 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.00593625 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0059339 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.00592144 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.00591748 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.00591146 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.00590339 |
| REG1A | regenerating islet-derived 1 alpha | -0.00589709 |
| C10ORF10 | chromosome 10 open reading frame 10 | -0.00589104 |
| MLF1 | myeloid leukemia factor 1 | -0.00587544 |
| CD69 | CD69 molecule | -0.00586933 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | -0.00586481 |
| SLC16A4 | solute carrier family 16, member 4 | -0.00586212 |
| HSPA8 | heat shock 70kDa protein 8 | -0.005854 |
| OLFML3 | olfactomedin-like 3 | -0.00585094 |
| MGLL | monoglyceride lipase | -0.0058491 |
| H1-2 | H1.2 linker histone, cluster member | -0.00584615 |
| CALCOCO2 | calcium binding and coiled-coil domain 2 | -0.00584552 |
| DES | desmin | -0.00583875 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | -0.00582881 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.00582823 |
| ACKR1 | atypical chemokine receptor 1 (Duffy blood group) | -0.00579904 |
| APOL2 | apolipoprotein L, 2 | -0.00578576 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.00577992 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | -0.00577782 |
| LAMA4 | laminin, alpha 4 | -0.00576812 |
| PSCA | prostate stem cell antigen | -0.00575003 |
| GRN | granulin | -0.00574766 |
| ZFP36 | ZFP36 ring finger protein | -0.00574663 |
| DEFB1 | defensin, beta 1 | -0.00574504 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 | -0.00573489 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | -0.00572346 |
| MSX1 | msh homeobox 1 | -0.00570523 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.00569949 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | -0.00569772 |
| SLC18A1 | solute carrier family 18 (vesicular monoamine transporter), member 1 | -0.0056912 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.00568189 |
| WFDC2 | WAP four-disulfide core domain 2 | -0.00567389 |
| MT1M | metallothionein 1M | -0.00566415 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.00566082 |
| MMP1 | matrix metallopeptidase 1 | -0.00565995 |
| NPR1 | natriuretic peptide receptor 1 | -0.00565814 |
| GLA | galactosidase, alpha | -0.00565153 |
| TMEM100 | transmembrane protein 100 | -0.00564308 |
| PCDH9 | protocadherin 9 | -0.00564167 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.00563345 |
| FAM111A | family with sequence similarity 111, member A | -0.00562759 |
| MPPED2 | metallophosphoesterase domain containing 2 | -0.00560937 |
| KLF4 | Kruppel-like factor 4 (gut) | -0.00559527 |
| SPON2 | spondin 2, extracellular matrix protein | -0.00559106 |
