RORA Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description RAR-related orphan receptor A|The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2014] (NCBI Entrez Gene Database, 6095)
External Link https://ncbi.nlm.nih.gov/gene/6095
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Genes

500 genes differentially expressed following the RORA gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.021155
DLK1 delta-like 1 homolog (Drosophila) 0.0174734
MGP matrix Gla protein 0.014432
ARID4A AT rich interactive domain 4A (RBP1-like) 0.0142284
ALCAM activated leukocyte cell adhesion molecule 0.0137133
IFI6 interferon, alpha-inducible protein 6 0.0135135
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.0134411
ADD3 adducin 3 (gamma) 0.0129069
SCG5 secretogranin V 0.0129033
AGR2 anterior gradient 2 0.0123559
AZGP1 alpha-2-glycoprotein 1, zinc-binding 0.0123222
PROM1 prominin 1 0.0121025
APOD apolipoprotein D 0.0120506
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.0119126
FRZB frizzled-related protein 0.0118806
OLFM4 olfactomedin 4 0.011805
SPAG16 sperm associated antigen 16 0.0117711
TSPAN13 tetraspanin 13 0.0116595
VCAN versican 0.0115951
TSPYL5 TSPY-like 5 0.0113789
NPY1R neuropeptide Y receptor Y1 0.0113601
ICAM2 intercellular adhesion molecule 2 0.0110801
ADO 2-aminoethanethiol (cysteamine) dioxygenase 0.0109397
LCN2 lipocalin 2 0.0109302
ZBTB20 zinc finger and BTB domain containing 20 0.0109087
SCUBE2 signal peptide, CUB domain, EGF-like 2 0.010664
AQP1 aquaporin 1 (Colton blood group) 0.0106375
SIRT3 sirtuin 3 0.010596
MMP7 matrix metallopeptidase 7 0.0105726
NOTCH2NL notch 2 N-terminal like 0.01047
EIF5A eukaryotic translation initiation factor 5A 0.0104476
MDK midkine (neurite growth-promoting factor 2) 0.0104356
ESR1 estrogen receptor 1 0.0103504
LGALS1 lectin, galactoside-binding, soluble, 1 0.010187
ALOX5 arachidonate 5-lipoxygenase 0.0101667
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.0101098
MSMB microseminoprotein, beta- 0.0100971
MAGED1 melanoma antigen family D1 0.00990986
NPIPB3 nuclear pore complex interacting protein family, member B3 0.0098357
PDLIM5 PDZ and LIM domain 5 0.00977938
EDNRA endothelin receptor type A 0.00967778
BGN biglycan 0.00959566
ZNF587 zinc finger protein 587 0.00958118
TFF3 trefoil factor 3 (intestinal) 0.0095055
NIBAN1 niban apoptosis regulator 1 0.00942735
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.00938348
FGFR3 fibroblast growth factor receptor 3 0.00934991
PTP4A3 protein tyrosine phosphatase type IVA, member 3 0.00934025
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.00931952
COL14A1 collagen, type XIV, alpha 1 0.00904735
EPCAM epithelial cell adhesion molecule 0.00899933
DPYSL3 dihydropyrimidinase-like 3 0.008935
RAMP1 receptor (G protein-coupled) activity modifying protein 1 0.00882127
THBS4 thrombospondin 4 0.00861682
FGF13 fibroblast growth factor 13 0.00854022
TFPI2 tissue factor pathway inhibitor 2 0.00853493
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 0.00852119
ADGRG2 adhesion G protein-coupled receptor G2 0.0085075
AEBP1 AE binding protein 1 0.00845363
LDLRAD4 low density lipoprotein receptor class A domain containing 4 0.00839866
HOPX HOP homeobox 0.00838846
PENK proenkephalin 0.00834489
HBB hemoglobin, beta 0.00833744
CHRDL1 chordin-like 1 0.00832167
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.00831017
PNMA8A PNMA family member 8A 0.00830187
MX1 MX dynamin-like GTPase 1 0.00829091
LEF1 lymphoid enhancer-binding factor 1 0.0082868
TNNT1 troponin T type 1 (skeletal, slow) 0.00819793
THBS1 thrombospondin 1 0.00819774
GREB1 growth regulation by estrogen in breast cancer 1 0.00818844
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 0.00811181
SSPN sarcospan 0.00808042
CLGN calmegin 0.00805757
STK39 serine threonine kinase 39 0.00805387
MAGED2 melanoma antigen family D2 0.00803608
TMEM63A transmembrane protein 63A 0.00803553
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 0.0080039
RPS4Y1 ribosomal protein S4, Y-linked 1 0.00799682
S100P S100 calcium binding protein P 0.00797536
MATN2 matrilin 2 0.00791305
BARD1 BRCA1 associated RING domain 1 0.00790142
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) 0.00789054
ZNF721 zinc finger protein 721 0.00784928
LYPD1 LY6/PLAUR domain containing 1 0.00783762
SFRP4 secreted frizzled-related protein 4 0.00777682
BHLHE41 basic helix-loop-helix family, member e41 0.00776451
TTC39A tetratricopeptide repeat domain 39A 0.00775138
ISLR immunoglobulin superfamily containing leucine-rich repeat 0.00768148
ZNF160 zinc finger protein 160 0.00763345
GOLGA8H golgin A8 family, member H 0.00760224
PLAAT3 phospholipase A and acyltransferase 3 0.00759401
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 0.0075839
ADIRF adipogenesis regulatory factor 0.00757942
SYT1 synaptotagmin I 0.0075578
MFAP2 microfibrillar-associated protein 2 0.00754916
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.00754326
IFITM1 interferon induced transmembrane protein 1 0.00752761
ISG15 ISG15 ubiquitin-like modifier 0.00752658
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.00752387
COL2A1 collagen, type II, alpha 1 0.00751502
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.00746722
RNF144A ring finger protein 144A 0.00746343
QPRT quinolinate phosphoribosyltransferase 0.00742613
HAUS2 HAUS augmin-like complex, subunit 2 0.00741771
KRT19 keratin 19, type I 0.00739623
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 0.0073868
AZF1 azoospermia factor 1 0.00738368
MXRA5 matrix-remodelling associated 5 0.00732976
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 0.00732566
SRPX sushi-repeat containing protein, X-linked 0.00728453
C1ORF54 chromosome 1 open reading frame 54 0.00727097
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 0.00726043
G3BP2 GTPase activating protein (SH3 domain) binding protein 2 0.0072497
PDGFC platelet derived growth factor C 0.0072044
FABP4 fatty acid binding protein 4, adipocyte 0.00719841
TARP TCR gamma alternate reading frame protein 0.00718967
METTL7A methyltransferase like 7A 0.00712472
ABAT 4-aminobutyrate aminotransferase 0.00711759
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 0.00710106
SCN3A sodium channel, voltage gated, type III alpha subunit 0.00709287
SCGB2A2 secretoglobin, family 2A, member 2 0.00708392
ATP5ME ATP synthase membrane subunit e 0.00708082
SERINC5 serine incorporator 5 0.00702581
NAMPT nicotinamide phosphoribosyltransferase 0.00700502
DLG5 discs, large homolog 5 (Drosophila) 0.00698477
CSAD cysteine sulfinic acid decarboxylase 0.00698008
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.00697852
DEGS1 delta(4)-desaturase, sphingolipid 1 0.00697108
CCND2 cyclin D2 0.00693561
GDF15 growth differentiation factor 15 0.00693289
SPON2 spondin 2, extracellular matrix protein 0.00690651
PELI1 pellino E3 ubiquitin protein ligase 1 0.00687238
STEAP1 six transmembrane epithelial antigen of the prostate 1 0.00686765
LY75 lymphocyte antigen 75 0.00683426
COMP cartilage oligomeric matrix protein 0.00683332
SPINK1 serine peptidase inhibitor, Kazal type 1 0.00682424
FBXW12 F-box and WD repeat domain containing 12 0.0068037
PBX1 pre-B-cell leukemia homeobox 1 0.00679083
TRIM14 tripartite motif containing 14 0.00679065
MT1M metallothionein 1M 0.00676365
SCRG1 stimulator of chondrogenesis 1 0.0067343
TRIM8 tripartite motif containing 8 0.00672632
GUSB glucuronidase, beta 0.00670478
MYBPC1 myosin binding protein C, slow type 0.00669907
ARHGAP6 Rho GTPase activating protein 6 0.00669813
ELN elastin 0.00668873
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.0066827
SUCO SUN domain containing ossification factor 0.00667818
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 0.00667535
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) 0.00665961
SLC39A8 solute carrier family 39 (zinc transporter), member 8 0.00664334
BIN1 bridging integrator 1 0.00663977
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00663794
ZNF217 zinc finger protein 217 0.00661945
PIP prolactin-induced protein 0.00660149
MAMLD1 mastermind-like domain containing 1 0.00660051
TSPAN8 tetraspanin 8 0.00658277
ARL4A ADP-ribosylation factor-like 4A 0.00658263
ARMCX6 armadillo repeat containing, X-linked 6 0.00656542
IRF7 interferon regulatory factor 7 0.00655941
MT1X metallothionein 1X 0.00655418
COX7B cytochrome c oxidase subunit VIIb 0.00655268
DCLK1 doublecortin-like kinase 1 0.00654211
E2F3 E2F transcription factor 3 0.00652056
FBLN2 fibulin 2 0.00651205
CFD complement factor D (adipsin) 0.00647746
ASCL1 achaete-scute family bHLH transcription factor 1 0.00647683
ASRGL1 asparaginase like 1 0.00643617
LHFP lipoma HMGIC fusion partner 0.00643088
PHF20 PHD finger protein 20 0.00642302
NEFH neurofilament, heavy polypeptide 0.00642039
ZNF611 zinc finger protein 611 0.00641854
KIF3A kinesin family member 3A 0.00640165
PTPRD protein tyrosine phosphatase, receptor type, D 0.00639732
HELLS helicase, lymphoid-specific 0.00638019
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 0.00637441
CCN2 cellular communication network factor 2 0.00636813
COL10A1 collagen, type X, alpha 1 0.00636421
BCHE butyrylcholinesterase 0.00634584
CBR3 carbonyl reductase 3 0.00634571
ECM1 extracellular matrix protein 1 0.00634497
CYBA cytochrome b-245, alpha polypeptide 0.00633488
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.00632926
CTSD cathepsin D 0.0063274
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.00631977
HTRA1 HtrA serine peptidase 1 0.00630767
IGF1 insulin-like growth factor 1 (somatomedin C) 0.00630739
CLEC11A C-type lectin domain family 11, member A 0.00630661
QPCT glutaminyl-peptide cyclotransferase 0.00630416
MEG3 maternally expressed 3 (non-protein coding) 0.00627075
VWF von Willebrand factor 0.00626201
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 0.00625405
NPY neuropeptide Y 0.00624428
ADAM9 ADAM metallopeptidase domain 9 0.00624318
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.00620392
COL1A2 collagen, type I, alpha 2 0.00620292
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 0.00618287
SPON1 spondin 1, extracellular matrix protein 0.00617668
ARMCX3 armadillo repeat containing, X-linked 3 0.00615962
ANO1 anoctamin 1, calcium activated chloride channel 0.00615845
MAP9 microtubule-associated protein 9 0.00615281
CD300A CD300a molecule 0.00614282
TSNAX translin-associated factor X 0.00614071
KLK2 kallikrein-related peptidase 2 0.00613965
FGFR1 fibroblast growth factor receptor 1 0.00611956
MAP1B microtubule-associated protein 1B 0.00611287
NKX2-2 NK2 homeobox 2 0.00609154
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 0.00608099
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 0.00607882
ZNF329 zinc finger protein 329 0.0060728
LOC283683 uncharacterized LOC283683 0.00607137
KIAA0355 KIAA0355 0.00606513
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.00605542
AREG amphiregulin 0.00604755
MYH10 myosin, heavy chain 10, non-muscle 0.00598616
TIMP1 TIMP metallopeptidase inhibitor 1 0.00597787
PLA2G12A phospholipase A2, group XIIA 0.00596434
SLC30A1 solute carrier family 30 (zinc transporter), member 1 0.00596362
TMEM41B transmembrane protein 41B 0.00596332
BPHL biphenyl hydrolase-like (serine hydrolase) 0.00593318
NCF2 neutrophil cytosolic factor 2 0.00592238
CLDN3 claudin 3 0.00591601
VAMP8 vesicle-associated membrane protein 8 0.00590759
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.00589738
SELPLG selectin P ligand 0.00589714
ZNF652 zinc finger protein 652 0.00589635
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 0.00588875
FN1 fibronectin 1 0.00587736
MAGEB2 melanoma antigen family B2 0.0058753
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 0.00587341
FAM107A family with sequence similarity 107, member A 0.00586228
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 0.00584893
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.00584716
G0S2 G0/G1 switch 2 0.00582956
BAD BCL2-associated agonist of cell death 0.00582834
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) 0.00582332
METTL5 methyltransferase like 5 0.00581844
RTN3 reticulon 3 0.00581416
DHDDS dehydrodolichyl diphosphate synthase 0.00581145
ZNF423 zinc finger protein 423 0.00580942
TUBA1A tubulin, alpha 1a 0.00580656
NUP58 nucleoporin 58 0.00580283
KLF10 Kruppel-like factor 10 0.00579562
MAPT microtubule-associated protein tau 0.00579165
TMC5 transmembrane channel-like 5 0.0057884
MSLN mesothelin 0.00578819
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene) 0.00577748
LAMP1 lysosomal-associated membrane protein 1 0.0057692
TMSB15A thymosin beta 15a 0.00575505

decreased expression

Symbol Name Standardized Value
CXCL9 chemokine (C-X-C motif) ligand 9 -0.0168441
CHEK2 checkpoint kinase 2 -0.0142174
CA2 carbonic anhydrase II -0.012004
CXCL13 chemokine (C-X-C motif) ligand 13 -0.0116403
CXCL10 chemokine (C-X-C motif) ligand 10 -0.0115307
ADAMDEC1 ADAM-like, decysin 1 -0.0114942
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 -0.0114181
S100A2 S100 calcium binding protein A2 -0.0111618
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -0.0110999
KRT16 keratin 16, type I -0.0110955
ZDHHC6 zinc finger, DHHC-type containing 6 -0.0109691
KRT6A keratin 6A, type II -0.0103001
SPRR1B small proline-rich protein 1B -0.00990412
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) -0.00977721
SPRR1A small proline-rich protein 1A -0.00970846
DUSP2 dual specificity phosphatase 2 -0.00956911
SPRR3 small proline-rich protein 3 -0.00956176
TAGLN2 transgelin 2 -0.00945362
S100A7 S100 calcium binding protein A7 -0.00938602
PI3 peptidase inhibitor 3, skin-derived -0.00923282
BSG basigin (Ok blood group) -0.0090531
IL32 interleukin 32 -0.00904388
NDRG1 N-myc downstream regulated 1 -0.00869948
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.00867806
KRT17 keratin 17, type I -0.00861435
LYPD3 LY6/PLAUR domain containing 3 -0.00848231
KLF9 Kruppel-like factor 9 -0.00847052
SDC2 syndecan 2 -0.00835719
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -0.00828812
H1-0 H1.0 linker histone -0.00826671
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 -0.00812211
KRT14 keratin 14, type I -0.00810751
GBP2 guanylate binding protein 2, interferon-inducible -0.00808293
SNX11 sorting nexin 11 -0.00802969
RAI14 retinoic acid induced 14 -0.00802459
TRIM29 tripartite motif containing 29 -0.00796275
PFKL phosphofructokinase, liver -0.00787613
CARMIL1 capping protein regulator and myosin 1 linker 1 -0.00786362
KRT6B keratin 6B, type II -0.00782366
IFRD2 interferon-related developmental regulator 2 -0.00779401
RHCG Rh family, C glycoprotein -0.00772729
CADM1 cell adhesion molecule 1 -0.00760742
RAD23B RAD23 homolog B (S. cerevisiae) -0.0075983
PTPRM protein tyrosine phosphatase, receptor type, M -0.0075968
ASPH aspartate beta-hydroxylase -0.00757978
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 -0.0075765
BTG3 BTG family, member 3 -0.00757587
TNC tenascin C -0.00755187
TFRC transferrin receptor -0.0075392
MMP12 matrix metallopeptidase 12 -0.00750074
CLTB clathrin, light chain B -0.00736523
PLS3 plastin 3 -0.0073631
SPRR2B small proline-rich protein 2B -0.00733934
SLCO4A1 solute carrier organic anion transporter family, member 4A1 -0.00732816
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene -0.00730863
IVNS1ABP influenza virus NS1A binding protein -0.00725751
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -0.00722311
RAB5C RAB5C, member RAS oncogene family -0.00712627
S100A10 S100 calcium binding protein A10 -0.0071207
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 -0.00709998
IL1B interleukin 1, beta -0.00709991
CYB5A cytochrome b5 type A (microsomal) -0.00709457
MMP9 matrix metallopeptidase 9 -0.00708715
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 -0.00707952
ETHE1 ethylmalonic encephalopathy 1 -0.00706287
SPINK5 serine peptidase inhibitor, Kazal type 5 -0.00704921
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) -0.00701123
TPM4 tropomyosin 4 -0.00697013
YIPF5 Yip1 domain family, member 5 -0.00692714
AURKB aurora kinase B -0.0069252
IRF8 interferon regulatory factor 8 -0.00692473
REEP5 receptor accessory protein 5 -0.00689703
SRSF1 serine/arginine-rich splicing factor 1 -0.00689524
STOM stomatin -0.00686944
DLG1 discs, large homolog 1 (Drosophila) -0.0067985
FBL fibrillarin -0.00669913
NMD3 NMD3 ribosome export adaptor -0.00668218
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 -0.00667852
TPI1 triosephosphate isomerase 1 -0.00666308
SIK1 salt-inducible kinase 1 -0.00661981
ELL2 elongation factor, RNA polymerase II, 2 -0.00661046
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.00659548
CD2 CD2 molecule -0.00656248
NNT nicotinamide nucleotide transhydrogenase -0.00655302
CLPTM1 cleft lip and palate associated transmembrane protein 1 -0.00654717
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -0.00654081
PERP PERP, TP53 apoptosis effector -0.00652694
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.00649295
PPL periplakin -0.0064853
LYZ lysozyme -0.00647771
EHBP1 EH domain binding protein 1 -0.00643517
ZFAND5 zinc finger, AN1-type domain 5 -0.0064341
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -0.00641944
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -0.00638378
L1CAM L1 cell adhesion molecule -0.00637666
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa -0.00636312
CLCA4 chloride channel accessory 4 -0.0063619
KLF4 Kruppel-like factor 4 (gut) -0.006328
RNF130 ring finger protein 130 -0.00632633
CHGB chromogranin B -0.00632377
TYMP thymidine phosphorylase -0.00631345
FSTL3 follistatin-like 3 (secreted glycoprotein) -0.00629051
MICALL1 MICAL-like 1 -0.00628457
YME1L1 YME1-like 1 ATPase -0.0062794
PRMT1 protein arginine methyltransferase 1 -0.0062747
NCK1 NCK adaptor protein 1 -0.00627452
MDFIC MyoD family inhibitor domain containing -0.0062745
LGALS2 lectin, galactoside-binding, soluble, 2 -0.00624331
MPZL2 myelin protein zero-like 2 -0.00623953
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha -0.00621682
CALML3 calmodulin-like 3 -0.00620765
ABLIM1 actin binding LIM protein 1 -0.00620714
EPAS1 endothelial PAS domain protein 1 -0.00620168
PREPL prolyl endopeptidase-like -0.00619837
CD177 CD177 molecule -0.00615344
DNM1L dynamin 1-like -0.00615043
IDO1 indoleamine 2,3-dioxygenase 1 -0.0061399
PLEK2 pleckstrin 2 -0.00610719
SFRP1 secreted frizzled-related protein 1 -0.00606962
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A -0.00605633
KANK1 KN motif and ankyrin repeat domains 1 -0.00604619
DRAM1 DNA-damage regulated autophagy modulator 1 -0.00604012
P3H2 prolyl 3-hydroxylase 2 -0.00600717
ACTN4 actinin, alpha 4 -0.0060019
CGGBP1 CGG triplet repeat binding protein 1 -0.00599654
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) -0.00599224
MAT2B methionine adenosyltransferase II, beta -0.00598952
CLIC4 chloride intracellular channel 4 -0.005967
BASP1 brain abundant, membrane attached signal protein 1 -0.00596197
CTSC cathepsin C -0.00595279
MCM5 minichromosome maintenance complex component 5 -0.00594482
IL2RB interleukin 2 receptor, beta -0.00592793
HACD3 3-hydroxyacyl-CoA dehydratase 3 -0.00591718
PEX2 peroxisomal biogenesis factor 2 -0.00590875
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 -0.00590619
NT5DC2 5'-nucleotidase domain containing 2 -0.00590355
GPX3 glutathione peroxidase 3 -0.00587255
CUL1 cullin 1 -0.00587101
EPB41L4B erythrocyte membrane protein band 4.1 like 4B -0.00586599
GET3 guided entry of tail-anchored proteins factor 3, ATPase -0.00582703
SH3BP4 SH3-domain binding protein 4 -0.00579522
NSFL1C NSFL1 (p97) cofactor (p47) -0.00579497
CNBP CCHC-type zinc finger, nucleic acid binding protein -0.00579409
PLEK pleckstrin -0.00579148
PHB2 prohibitin 2 -0.005775
DSP desmoplakin -0.00577342
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 -0.0057705
DUSP1 dual specificity phosphatase 1 -0.00576949
GCK glucokinase (hexokinase 4) -0.00576609
RAB32 RAB32, member RAS oncogene family -0.00575377
JUNB jun B proto-oncogene -0.00574497
RBKS ribokinase -0.00573887
S100A9 S100 calcium binding protein A9 -0.00573138
MXI1 MAX interactor 1, dimerization protein -0.00572023
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -0.00570524
PUM3 pumilio RNA binding family member 3 -0.00570461
IDE insulin-degrading enzyme -0.0056965
PPP5C protein phosphatase 5, catalytic subunit -0.00569493
CCT4 chaperonin containing TCP1, subunit 4 (delta) -0.00568687
KYNU kynureninase -0.00567713
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 -0.0056741
TUBB2A tubulin, beta 2A class IIa -0.0056721
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha -0.00564342
SGPP1 sphingosine-1-phosphate phosphatase 1 -0.0056434
ALPL alkaline phosphatase, liver/bone/kidney -0.00563113
TMEM45A transmembrane protein 45A -0.00562069
STC1 stanniocalcin 1 -0.00561624
AP2M1 adaptor-related protein complex 2, mu 1 subunit -0.00561502
TXN thioredoxin -0.00560915
LOX lysyl oxidase -0.00557941
CXADR coxsackie virus and adenovirus receptor -0.00557874
PPP1R15A protein phosphatase 1, regulatory subunit 15A -0.00556074
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2 -0.00554133
CD14 CD14 molecule -0.0055411
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) -0.00553114
LMAN1 lectin, mannose-binding, 1 -0.00552817
ELP1 elongator acetyltransferase complex subunit 1 -0.00552141
KPNA4 karyopherin alpha 4 (importin alpha 3) -0.00551602
TUBB4B tubulin, beta 4B class IVb -0.00550275
POLRMT polymerase (RNA) mitochondrial (DNA directed) -0.00549711
SLC38A1 solute carrier family 38, member 1 -0.0054767
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 -0.00546043
GOT1 glutamic-oxaloacetic transaminase 1, soluble -0.00545348
STMN2 stathmin 2 -0.00544859
PFN2 profilin 2 -0.00543827
SELENOT selenoprotein T -0.00543171
PHF10 PHD finger protein 10 -0.00541787
GPI glucose-6-phosphate isomerase -0.00541094
STAT1 signal transducer and activator of transcription 1, 91kDa -0.00540421
PLVAP plasmalemma vesicle associated protein -0.00540367
ARF3 ADP-ribosylation factor 3 -0.00539762
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 -0.00539746
CD59 CD59 molecule, complement regulatory protein -0.00538809
TGFBI transforming growth factor, beta-induced, 68kDa -0.00538794
SLC38A2 solute carrier family 38, member 2 -0.00538054
STAP2 signal transducing adaptor family member 2 -0.00537578
HOOK2 hook microtubule-tethering protein 2 -0.00537295
DSG3 desmoglein 3 -0.00537267
ASCC2 activating signal cointegrator 1 complex subunit 2 -0.00537247
RALB v-ral simian leukemia viral oncogene homolog B -0.0053723
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 -0.00535208
PAM peptidylglycine alpha-amidating monooxygenase -0.00534956
COL4A2 collagen, type IV, alpha 2 -0.00533171
VLDLR very low density lipoprotein receptor -0.00533143
MLF2 myeloid leukemia factor 2 -0.00532931
HACD1 3-hydroxyacyl-CoA dehydratase 1 -0.00530596
FGFBP1 fibroblast growth factor binding protein 1 -0.00530439
COPS2 COP9 signalosome subunit 2 -0.00530326
GARS1 glycyl-tRNA synthetase 1 -0.00529423
TNS3 tensin 3 -0.00528712
PCNA proliferating cell nuclear antigen -0.00527865
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2 -0.0052772
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) -0.00526174
U2AF1 U2 small nuclear RNA auxiliary factor 1 -0.005257
TCP1 t-complex 1 -0.00524567
GNAS GNAS complex locus -0.00524468
EIF3D eukaryotic translation initiation factor 3, subunit D -0.00524366
HARS1 histidyl-tRNA synthetase 1 -0.00524328
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 -0.00524078
S100A8 S100 calcium binding protein A8 -0.00523196
IGSF3 immunoglobulin superfamily, member 3 -0.00522989
SFN stratifin -0.00519368
IL1RN interleukin 1 receptor antagonist -0.00518856
SET SET nuclear proto-oncogene -0.00517939
MRPS2 mitochondrial ribosomal protein S2 -0.00517272
P2RY2 purinergic receptor P2Y, G-protein coupled, 2 -0.00516702
PNRC1 proline-rich nuclear receptor coactivator 1 -0.00514707
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae) -0.00514681
TMEM230 transmembrane protein 230 -0.00514457
RPL10 ribosomal protein L10 -0.00513695
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -0.00513376
ALDOA aldolase A, fructose-bisphosphate -0.00512333
TRAF1 TNF receptor-associated factor 1 -0.0051206
IL17RA interleukin 17 receptor A -0.00510862
TARS1 threonyl-tRNA synthetase 1 -0.0050849
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 -0.00507265
IRF1 interferon regulatory factor 1 -0.0050704
CRLF1 cytokine receptor-like factor 1 -0.00506357
SCO2 SCO2 cytochrome c oxidase assembly protein -0.00505134
PCBP4 poly(rC) binding protein 4 -0.0050508
CD8A CD8a molecule -0.00504978
TNIP1 TNFAIP3 interacting protein 1 -0.00503274
HDHD5 haloacid dehalogenase like hydrolase domain containing 5 -0.00502465
BMP2 bone morphogenetic protein 2 -0.00502072
AVPI1 arginine vasopressin-induced 1 -0.00501305
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 -0.00501056
CBX6 chromobox homolog 6 -0.00501013
SINHCAF SIN3-HDAC complex associated factor -0.00500837
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2 -0.00500717
SRSF7 serine/arginine-rich splicing factor 7 -0.00500708