RORA Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description RAR-related orphan receptor A|The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2014] (NCBI Entrez Gene Database, 6095)
External Link http://www.ncbi.nlm.nih.gov/gene/6095
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30 interacting proteins for RORA from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ATXN1 ataxin 1
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
COPS5 COP9 signalosome subunit 5
DDB1 damage-specific DNA binding protein 1, 127kDa
EIF3I eukaryotic translation initiation factor 3, subunit I
EP300 E1A binding protein p300
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
KAT5 K(lysine) acetyltransferase 5
LMO3 LIM domain only 3 (rhombotin-like 2)
LRIF1 ligand dependent nuclear receptor interacting factor 1
MAPK1 mitogen-activated protein kinase 1
MED1 mediator complex subunit 1
MYOD1 myogenic differentiation 1
NCOA1 nuclear receptor coactivator 1
NCOA2 nuclear receptor coactivator 2
NME1 NME/NM23 nucleoside diphosphate kinase 1
NME2 NME/NM23 nucleoside diphosphate kinase 2
NR0B1 nuclear receptor subfamily 0, group B, member 1
NSD1 nuclear receptor binding SET domain protein 1
PNRC1 proline-rich nuclear receptor coactivator 1
PNRC2 proline-rich nuclear receptor coactivator 2
PRKCA protein kinase C, alpha
PROX1 prospero homeobox 1
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5
PTBP1 polypyrimidine tract binding protein 1
RUVBL1 RuvB-like AAA ATPase 1
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
UBC ubiquitin C
VPRBP Vpr (HIV-1) binding protein
ZXDC ZXD family zinc finger C