RORC Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description RAR-related orphan receptor C|The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known; however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6097)
External Link http://www.ncbi.nlm.nih.gov/gene/6097
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23 interacting proteins for RORC from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
BHLHE40 basic helix-loop-helix family, member e40
CHD4 chromodomain helicase DNA binding protein 4
EIF3I eukaryotic translation initiation factor 3, subunit I
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EVI2A ecotropic viral integration site 2A
FBXL15 F-box and leucine-rich repeat protein 15
FOXP3 forkhead box P3
HNF4A hepatocyte nuclear factor 4, alpha
NCOA1 nuclear receptor coactivator 1
NCOA6 nuclear receptor coactivator 6
NPAS2 neuronal PAS domain protein 2
NR1D2 nuclear receptor subfamily 1, group D, member 2
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PPP2R5D protein phosphatase 2, regulatory subunit B', delta
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5
RORB RAR-related orphan receptor B