ROS-50 Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description cell line derived from -666 (Catalogue of Somatic Mutations In Cancer)
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Genes

326 genes mutated in the ROS-50 cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
AASS aminoadipate-semialdehyde synthase
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ABI3BP ABI family, member 3 (NESH) binding protein
ACOT12 acyl-CoA thioesterase 12
ADAM22 ADAM metallopeptidase domain 22
ADAMTS14 ADAM metallopeptidase with thrombospondin type 1 motif, 14
ADAMTS15 ADAM metallopeptidase with thrombospondin type 1 motif, 15
ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif, 18
ADAMTSL4 ADAMTS-like 4
ADARB1 adenosine deaminase, RNA-specific, B1
ADCY9 adenylate cyclase 9
ADGRG2 adhesion G protein-coupled receptor G2
ADGRV1 adhesion G protein-coupled receptor V1
AFAP1 actin filament associated protein 1
AGA aspartylglucosaminidase
AKAP12 A kinase (PRKA) anchor protein 12
ALDH16A1 aldehyde dehydrogenase 16 family, member A1
AMER2 APC membrane recruitment protein 2
AMOTL1 angiomotin like 1
ANKRD30B ankyrin repeat domain 30B
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
AQP12B aquaporin 12B
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
ARHGAP39 Rho GTPase activating protein 39
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARID1B AT rich interactive domain 1B (SWI1-like)
AS3MT arsenite methyltransferase
ASB10 ankyrin repeat and SOCS box containing 10
ATAD3C ATPase family, AAA domain containing 3C
ATR ATR serine/threonine kinase
AXIN1 axin 1
BAG6 BCL2-associated athanogene 6
BCL2 B-cell CLL/lymphoma 2
BCL3 B-cell CLL/lymphoma 3
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2
BTK Bruton agammaglobulinemia tyrosine kinase
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CASP12 caspase 12 (gene/pseudogene)
CASP8AP2 caspase 8 associated protein 2
CASS4 Cas scaffolding protein family member 4
CATSPER2 cation channel, sperm associated 2
CCDC138 coiled-coil domain containing 138
CCDC90B coiled-coil domain containing 90B
CCDC92 coiled-coil domain containing 92
CD200 CD200 molecule
CDHR5 cadherin-related family member 5
CDK11A cyclin-dependent kinase 11A
CDK11B cyclin-dependent kinase 11B
CDK13 cyclin-dependent kinase 13
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
CGB1 chorionic gonadotropin, beta polypeptide 1
CHRND cholinergic receptor, nicotinic, delta (muscle)
CKAP5 cytoskeleton associated protein 5
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric)
CLASP2 cytoplasmic linker associated protein 2
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
CMKLR1 chemerin chemokine-like receptor 1
CPT1C carnitine palmitoyltransferase 1C
CRIP3 cysteine-rich protein 3
CRISP1 cysteine-rich secretory protein 1
CRISPLD1 cysteine-rich secretory protein LCCL domain containing 1
CSMD1 CUB and Sushi multiple domains 1
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CSRNP3 cysteine-serine-rich nuclear protein 3
CTU2 cytosolic thiouridylase subunit 2 homolog (S. pombe)
CUL1 cullin 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2A13 cytochrome P450, family 2, subfamily A, polypeptide 13
DDIT3 DNA-damage-inducible transcript 3
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DENND6A DENN/MADD domain containing 6A
DFNB31 deafness, autosomal recessive 31
DLC1 DLC1 Rho GTPase activating protein
DNAAF3 dynein, axonemal, assembly factor 3
DOCK5 dedicator of cytokinesis 5
DST dystonin
DUOX2 dual oxidase 2
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
EHD3 EH-domain containing 3
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative)
EPB41L4A erythrocyte membrane protein band 4.1 like 4A
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ETFDH electron-transferring-flavoprotein dehydrogenase
ETV3 ets variant 3
EVPL envoplakin
EXTL2 exostosin-like glycosyltransferase 2
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FAM109A family with sequence similarity 109, member A
FAM122C family with sequence similarity 122C
FAM129B family with sequence similarity 129, member B
FAM167A family with sequence similarity 167, member A
FANCG Fanconi anemia, complementation group G
FAT3 FAT atypical cadherin 3
FMN1 formin 1
FOXE1 forkhead box E1
FOXN4 forkhead box N4
FXR2 fragile X mental retardation, autosomal homolog 2
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3
GAL3ST1 galactose-3-O-sulfotransferase 1
GATA2 GATA binding protein 2
GET4 golgi to ER traffic protein 4 homolog (S. cerevisiae)
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPATCH3 G patch domain containing 3
GRB14 growth factor receptor-bound protein 14
GRK5 G protein-coupled receptor kinase 5
GRM1 glutamate receptor, metabotropic 1
GTF2IRD1 GTF2I repeat domain containing 1
H19 H19, imprinted maternally expressed transcript (non-protein coding)
HAPLN1 hyaluronan and proteoglycan link protein 1
HCRTR2 hypocretin (orexin) receptor 2
HDAC5 histone deacetylase 5
HEATR5A HEAT repeat containing 5A
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2
HLA-B major histocompatibility complex, class I, B
HLTF helicase-like transcription factor
HRNR hornerin
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12
HYDIN HYDIN, axonemal central pair apparatus protein
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase
IL17REL interleukin 17 receptor E-like
IL31RA interleukin 31 receptor A
INSM1 insulinoma-associated 1
INTS10 integrator complex subunit 10
IRX3 iroquois homeobox 3
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
KALRN kalirin, RhoGEF kinase
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
KCNIP3 Kv channel interacting protein 3, calsenilin
KDM6B lysine (K)-specific demethylase 6B
KIAA0319 KIAA0319
KIAA0895 KIAA0895
KIAA1671 KIAA1671
KIAA2018 KIAA2018
KLB klotho beta
KLHL26 kelch-like family member 26
KLHL6 kelch-like family member 6
KSR1 kinase suppressor of ras 1
LAMA2 laminin, alpha 2
LIMS1 LIM and senescent cell antigen-like domains 1
LPA lipoprotein, Lp(a)
LPIN3 lipin 3
LPPR1 lipid phosphate phosphatase-related protein type 1
LRRC8D leucine rich repeat containing 8 family, member D
LRRK2 leucine-rich repeat kinase 2
LTB lymphotoxin beta (TNF superfamily, member 3)
LYPD6B LY6/PLAUR domain containing 6B
MAP3K19 mitogen-activated protein kinase kinase kinase 19
MCPH1 microcephalin 1
MEF2C myocyte enhancer factor 2C
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
MFSD1 major facilitator superfamily domain containing 1
MFSD12 major facilitator superfamily domain containing 12
MKI67 marker of proliferation Ki-67
MOXD1 monooxygenase, DBH-like 1
MRPL22 mitochondrial ribosomal protein L22
MSH2 mutS homolog 2
MSLNL mesothelin-like
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MUC12 mucin 12, cell surface associated
MUC4 mucin 4, cell surface associated
MUC6 mucin 6, oligomeric mucus/gel-forming
MXRA5 matrix-remodelling associated 5
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYO15A myosin XVA
MYO1D myosin ID
NAGS N-acetylglutamate synthase
NALCN sodium leak channel, non selective
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative)
NAV1 neuron navigator 1
NEBL nebulette
NELFE negative elongation factor complex member E
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NIN ninein (GSK3B interacting protein)
NLRP2 NLR family, pyrin domain containing 2
NOTCH3 notch 3
NPHP4 nephronophthisis 4
NPHS1 nephrosis 1, congenital, Finnish type (nephrin)
NRAP nebulin-related anchoring protein
NUP155 nucleoporin 155kDa
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OCA2 oculocutaneous albinism II
OGN osteoglycin
OR14A16 olfactory receptor, family 14, subfamily A, member 16
OR2D2 olfactory receptor, family 2, subfamily D, member 2
OR4N4 olfactory receptor, family 4, subfamily N, member 4
OR51B5 olfactory receptor, family 51, subfamily B, member 5
ORM1 orosomucoid 1
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PA2G4 proliferation-associated 2G4, 38kDa
PAAF1 proteasomal ATPase-associated factor 1
PCDHB16 protocadherin beta 16
PCDHGA6 protocadherin gamma subfamily A, 6
PCDHGA9 protocadherin gamma subfamily A, 9
PCSK5 proprotein convertase subtilisin/kexin type 5
PDLIM7 PDZ and LIM domain 7 (enigma)
PDXDC2P-NPIPB14P pyridoxal-dependent decarboxylase domain containing 2, pseudogene
PDZK1 PDZ domain containing 1
PDZRN4 PDZ domain containing ring finger 4
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PIK3C2G phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PKD1 polycystic kidney disease 1 (autosomal dominant)
PKD1L1 polycystic kidney disease 1 like 1
PKD1L3 polycystic kidney disease 1-like 3
PLEKHG4 pleckstrin homology domain containing, family G (with RhoGef domain) member 4
POM121L4P POM121 transmembrane nucleoporin-like 4 pseudogene
POTEC POTE ankyrin domain family, member C
POU5F1B POU class 5 homeobox 1B
PPFIA2 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
PPL periplakin
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
PTCD1 pentatricopeptide repeat domain 1
PTPRD protein tyrosine phosphatase, receptor type, D
PUS1 pseudouridylate synthase 1
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAB11FIP2 RAB11 family interacting protein 2 (class I)
RABGGTA Rab geranylgeranyltransferase, alpha subunit
RAD21L1 RAD21-like 1 (S. pombe)
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RASEF RAS and EF-hand domain containing
RBM34 RNA binding motif protein 34
RBMXL2 RNA binding motif protein, X-linked-like 2
REST RE1-silencing transcription factor
RFPL1 ret finger protein-like 1
RGPD3 RANBP2-like and GRIP domain containing 3
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RMDN1 regulator of microtubule dynamics 1
RNF169 ring finger protein 169
RNF183 ring finger protein 183
RPL18A ribosomal protein L18a
RYR1 ryanodine receptor 1 (skeletal)
SAMD9 sterile alpha motif domain containing 9
SBF1 SET binding factor 1
SCN2A sodium channel, voltage gated, type II alpha subunit
SCUBE2 signal peptide, CUB domain, EGF-like 2
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SEPN1 selenoprotein N, 1
SFTA3 surfactant associated 3
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SH2B3 SH2B adaptor protein 3
SH3RF1 SH3 domain containing ring finger 1
SIPA1L3 signal-induced proliferation-associated 1 like 3
SLC10A6 solute carrier family 10 (sodium/bile acid cotransporter), member 6
SLC22A12 solute carrier family 22 (organic anion/urate transporter), member 12
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SLCO5A1 solute carrier organic anion transporter family, member 5A1
SMC6 structural maintenance of chromosomes 6
SOBP sine oculis binding protein homolog (Drosophila)
SOWAHB sosondowah ankyrin repeat domain family member B
SOX13 SRY (sex determining region Y)-box 13
SPNS3 spinster homolog 3 (Drosophila)
SPTBN2 spectrin, beta, non-erythrocytic 2
SPTBN5 spectrin, beta, non-erythrocytic 5
SRP54 signal recognition particle 54kDa
SRPK3 SRSF protein kinase 3
STEAP1 six transmembrane epithelial antigen of the prostate 1
STK10 serine/threonine kinase 10
STK4 serine/threonine kinase 4
STRA6 stimulated by retinoic acid 6
STRADA STE20-related kinase adaptor alpha
SVIL supervillin
SYNJ2 synaptojanin 2
TACC2 transforming, acidic coiled-coil containing protein 2
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TBC1D16 TBC1 domain family, member 16
TBC1D21 TBC1 domain family, member 21
TC2N tandem C2 domains, nuclear
TFG TRK-fused gene
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TGM7 transglutaminase 7
TIAM1 T-cell lymphoma invasion and metastasis 1
TMEM222 transmembrane protein 222
TMX3 thioredoxin-related transmembrane protein 3
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TP53 tumor protein p53
TRIM37 tripartite motif containing 37
TSC2 tuberous sclerosis 2
TSC22D3 TSC22 domain family, member 3
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
TTLL11 tubulin tyrosine ligase-like family member 11
TTLL12 tubulin tyrosine ligase-like family member 12
TTLL5 tubulin tyrosine ligase-like family member 5
TTN titin
TWF1 twinfilin actin binding protein 1
U2AF1L4 U2 small nuclear RNA auxiliary factor 1-like 4
UBAP2 ubiquitin associated protein 2
UBE2G2 ubiquitin-conjugating enzyme E2G 2
UBE2I ubiquitin-conjugating enzyme E2I
UBXN10 UBX domain protein 10
UNC5D unc-5 homolog D (C. elegans)
USP38 ubiquitin specific peptidase 38
USP4 ubiquitin specific peptidase 4 (proto-oncogene)
VWA8 von Willebrand factor A domain containing 8
VWF von Willebrand factor
WDR53 WD repeat domain 53
WNK1 WNK lysine deficient protein kinase 1
WWC2 WW and C2 domain containing 2
ZBTB35 zinc finger and BTB domain containing 35
ZBTB40 zinc finger and BTB domain containing 40
ZC3H15 zinc finger CCCH-type containing 15
ZFYVE26 zinc finger, FYVE domain containing 26
ZNF174 zinc finger protein 174
ZNF248 zinc finger protein 248
ZNF280A zinc finger protein 280A
ZNF852 zinc finger protein 852
ZPLD1 zona pellucida-like domain containing 1
ZSCAN5D zinc finger and SCAN domain containing 5D