RPMI-7951 Gene Set

Dataset Sanger Dependency Map Cancer Cell Line Proteomics
Category proteomics
Type cell line
Description Human skin malignant melanoma cells that can be ordered from ATCC. This is a hyperdiploid human cell line with the modal chromosome number of 49, occurring in 24% of cells. Polyploid cells occurred at 22%, which is high. Cells are adherent, and were first harvested in 1971 from a metastatic site in a lymph node. (Experimental Factor Ontology, EFO_0005712)
External Link https://cellmodelpassports.sanger.ac.uk/passports/SIDM01087
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Genes

197 proteins associated with the cell line RPMI-7951 from the Sanger Dependency Map Cancer Cell Line Proteomics dataset.

Symbol Name
AASTH16 Allergic/atopic asthma related QTL 16
ABLIM1 actin binding LIM protein 1
ALG11 ALG11, alpha-1,2-mannosyltransferase
AP2M1 adaptor-related protein complex 2, mu 1 subunit
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
APMAP adipocyte plasma membrane associated protein
APOM apolipoprotein M
ARL8B ADP-ribosylation factor-like 8B
CDCP1 CUB domain containing protein 1
CHD2 chromodomain helicase DNA binding protein 2
CHPF chondroitin polymerizing factor
CLCN7 chloride channel, voltage-sensitive 7
CPOX coproporphyrinogen oxidase
CWF19L2 CWF19-like 2, cell cycle control (S. pombe)
CXADR coxsackie virus and adenovirus receptor
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
DENND5B DENN/MADD domain containing 5B
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
DST dystonin
ECE1 endothelin converting enzyme 1
EHD4 EH-domain containing 4
EXOC6B exocyst complex component 6B
FN1 fibronectin 1
GCC2 GRIP and coiled-coil domain containing 2
GDAP2 ganglioside induced differentiation associated protein 2
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa
ICAM1 intercellular adhesion molecule 1
ICMT isoprenylcysteine carboxyl methyltransferase
ILK integrin-linked kinase
IMP4 IMP4, U3 small nucleolar ribonucleoprotein
IQGAP2 IQ motif containing GTPase activating protein 2
IRS2 insulin receptor substrate 2
KIAA2013 KIAA2013
KIF20B kinesin family member 20B
KIF5C kinesin family member 5C
KMT2D lysine (K)-specific methyltransferase 2D
KRT1 keratin 1, type II
KRT10 keratin 10, type I
KRT2 keratin 2, type II
KRT73 keratin 73, type II
KRT77 keratin 77, type II
KRT84 keratin 84, type II
KRT9 keratin 9, type I
MAGT1 magnesium transporter 1
MESTP1 mesoderm specific transcript pseudogene 1
MGST3 microsomal glutathione S-transferase 3
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MTMR11 myotubularin related protein 11
MYH14 myosin, heavy chain 14, non-muscle
MYO1B myosin IB
NBAS neuroblastoma amplified sequence
NRP1 neuropilin 1
OCRL oculocerebrorenal syndrome of Lowe
OSTC oligosaccharyltransferase complex subunit (non-catalytic)
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PCF11 PCF11 cleavage and polyadenylation factor subunit
PER1 period circadian clock 1
PET100 PET100 homolog (S. cerevisiae)
PIGK phosphatidylinositol glycan anchor biosynthesis, class K
PIGT phosphatidylinositol glycan anchor biosynthesis, class T
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
PLCG1 phospholipase C, gamma 1
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
POFUT1 protein O-fucosyltransferase 1
PRAF2 PRA1 domain family, member 2
PRNP prion protein
PSME4 proteasome (prosome, macropain) activator subunit 4
RAB13 RAB13, member RAS oncogene family
RAB39A RAB39A, member RAS oncogene family
RAB7B RAB7B, member RAS oncogene family
RBBP6 retinoblastoma binding protein 6
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPGRIP1L RPGRIP1-like
RPN1 ribophorin I
RPN2 ribophorin II
RRAS related RAS viral (r-ras) oncogene homolog
SACK1F scaffolding CK1 anchoring protein F
SEC61B Sec61 beta subunit
SIM2 single-minded family bHLH transcription factor 2
SLC30A7 solute carrier family 30 (zinc transporter), member 7
SMPD4 sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)
SRPK1 SRSF protein kinase 1
STRN4 striatin, calmodulin binding protein 4
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
STT3B STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
SUN2 Sad1 and UNC84 domain containing 2
TFRC transferrin receptor
THBS1 thrombospondin 1
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)
TMEM214 transmembrane protein 214
TMEM70 transmembrane protein 70
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast)
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing

Symbol Name
ABI2 abl-interactor 2
ABR active BCR-related
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40
ATP11C ATPase, class VI, type 11C
ATPAF1 ATP synthase mitochondrial F1 complex assembly factor 1
ATXN2L ataxin 2-like
B3GALT6 UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6
BAIAP2L1 BAI1-associated protein 2-like 1
BRD7 bromodomain containing 7
BRINP1 bone morphogenetic protein/retinoic acid inducible neural-specific 1
C17ORF75 chromosome 17 open reading frame 75
C19ORF12 chromosome 19 open reading frame 12
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CC2D1A coiled-coil and C2 domain containing 1A
CDKN2A cyclin-dependent kinase inhibitor 2A
CENPV centromere protein V
CEP97 centrosomal protein 97kDa
CHMP3 charged multivesicular body protein 3
CUL4A cullin 4A
DDX19A DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A
DPP3 dipeptidyl-peptidase 3
DTX3L deltex 3 like, E3 ubiquitin ligase
DYNLT1 dynein, light chain, Tctex-type 1
ECT2 epithelial cell transforming 2
EIF4E2 eukaryotic translation initiation factor 4E family member 2
ENOPH1 enolase-phosphatase 1
ERCC4 excision repair cross-complementation group 4
FAM207A family with sequence similarity 207, member A
FDPS farnesyl diphosphate synthase
FLI1 Fli-1 proto-oncogene, ETS transcription factor
GABARAPL2 GABA(A) receptor-associated protein-like 2
GAN gigaxonin
GATAD2B GATA zinc finger domain containing 2B
GLUD2 glutamate dehydrogenase 2
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GOLPH3 golgi phosphoprotein 3 (coat-protein)
GPHN gephyrin
HMGN1 high mobility group nucleosome binding domain 1
IL17RA interleukin 17 receptor A
ISCA1 iron-sulfur cluster assembly 1
KIAA1217 KIAA1217
LARP1 La ribonucleoprotein domain family, member 1
LIG1 ligase I, DNA, ATP-dependent
LOC105369582 uncharacterized LOC105369582
LYPLAL1 lysophospholipase-like 1
MCEE methylmalonyl CoA epimerase
MEPCE methylphosphate capping enzyme
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae)
MPO myeloperoxidase
MRPL57 mitochondrial ribosomal protein L57
MVD mevalonate (diphospho) decarboxylase
NCOR1 nuclear receptor corepressor 1
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NUP210 nucleoporin 210kDa
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
POSTN periostin, osteoblast specific factor
PPP1R12BP1 protein phosphatase 1, regulatory subunit 12B pseudogene, Y-linked 1
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma
PPTC7 PTC7 protein phosphatase homolog (S. cerevisiae)
PRRC2A proline-rich coiled-coil 2A
PRRC2C proline-rich coiled-coil 2C
PSMG3 proteasome (prosome, macropain) assembly chaperone 3
PUM1 pumilio RNA-binding family member 1
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic)
RAD23A RAD23 homolog A (S. cerevisiae)
RBBP4 retinoblastoma binding protein 4
RBM33 RNA binding motif protein 33
RNF167 ring finger protein 167
RNF25 ring finger protein 25
RPL38 ribosomal protein L38
RPP25L ribonuclease P/MRP 25kDa subunit-like
SAAL1 serum amyloid A-like 1
SCAMP1 secretory carrier membrane protein 1
SCOC short coiled-coil protein
SH3GLB2 SH3-domain GRB2-like endophilin B2
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
STK39 serine threonine kinase 39
SUPT4H1 suppressor of Ty 4 homolog 1 (S. cerevisiae)
SUPT7L suppressor of Ty 7 (S. cerevisiae)-like
SYNC syncoilin, intermediate filament protein
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
TBCC tubulin folding cofactor C
THOC1 THO complex 1
TMEM41B transmembrane protein 41B
TRIM56 tripartite motif containing 56
TRIP4 thyroid hormone receptor interactor 4
TRMT61A tRNA methyltransferase 61A
USP8 ubiquitin specific peptidase 8
VCAN versican
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae)
WDR37 WD repeat domain 37
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1
ZC3H6 zinc finger CCCH-type containing 6
ZC3HC1 zinc finger, C3HC-type containing 1
ZDHHC20 zinc finger, DHHC-type containing 20