RPMI-8226 Gene Set

Dataset Sanger Dependency Map Cancer Cell Line Proteomics
Category proteomics
Type cell line
Description cell line derived from Plasma Cell Myeloma Tumour (Cell Model Passports, SIDM00087)
External Link https://cellmodelpassports.sanger.ac.uk/passports/SIDM00087
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Genes

197 proteins associated with the cell line RPMI-8226 from the Sanger Dependency Map Cancer Cell Line Proteomics dataset.

Symbol Name
ABHD14B abhydrolase domain containing 14B
ACAT1 acetyl-CoA acetyltransferase 1
ACSS2 acyl-CoA synthetase short-chain family member 2
ASS1 argininosuccinate synthase 1
ATXN3 ataxin 3
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1
BOD1L1 biorientation of chromosomes in cell division 1-like 1
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family)
COL3A1 collagen, type III, alpha 1
CORO7 coronin 7
CPNE3 copine III
CREG1 cellular repressor of E1A-stimulated genes 1
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DEPTOR DEP domain containing MTOR-interacting protein
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EEF2K eukaryotic elongation factor 2 kinase
ERP29 endoplasmic reticulum protein 29
EYA3 EYA transcriptional coactivator and phosphatase 3
FBXL8 F-box and leucine-rich repeat protein 8
FH fumarate hydratase
FKBP11 FK506 binding protein 11, 19 kDa
FKBP2 FK506 binding protein 2, 13kDa
GALK2 galactokinase 2
GIPC1 GIPC PDZ domain containing family, member 1
GMDS GDP-mannose 4,6-dehydratase
GMPPB GDP-mannose pyrophosphorylase B
GPX7 glutathione peroxidase 7
HIBCH 3-hydroxyisobutyryl-CoA hydrolase
HYOU1 hypoxia up-regulated 1
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
INPPL1 inositol polyphosphate phosphatase-like 1
IRF2BP1 interferon regulatory factor 2 binding protein 1
ISG20 interferon stimulated exonuclease gene 20kDa
ITGB7 integrin, beta 7
KIDINS220 kinase D-interacting substrate, 220kDa
LAP3 leucine aminopeptidase 3
LGMN legumain
LMAN1 lectin, mannose-binding, 1
LMAN2 lectin, mannose-binding 2
LOC105371474 uncharacterized LOC105371474
LOC442389 interferon induced transmembrane protein pseudogene
MACROD1 MACRO domain containing 1
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MCEE methylmalonyl CoA epimerase
MPG N-methylpurine-DNA glycosylase
MPHOSPH8 M-phase phosphoprotein 8
MROH6 maestro heat-like repeat family member 6
MRPS6 mitochondrial ribosomal protein S6
MYDGF myeloid-derived growth factor
MYO5A myosin VA (heavy chain 12, myoxin)
MZB1 marginal zone B and B1 cell-specific protein
NAPRT nicotinate phosphoribosyltransferase
NLN neurolysin (metallopeptidase M3 family)
NOB1 NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
NUDT8 nudix (nucleoside diphosphate linked moiety X)-type motif 8
ORC6 origin recognition complex, subunit 6
PAPOLA poly(A) polymerase alpha
PARP1 poly (ADP-ribose) polymerase 1
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PEX6 peroxisomal biogenesis factor 6
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
POP4 processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)
PPIB peptidylprolyl isomerase B (cyclophilin B)
PRDX4 peroxiredoxin 4
PRDX5 peroxiredoxin 5
PREB prolactin regulatory element binding
PVALB parvalbumin
REXO2 RNA exonuclease 2
RNF113A ring finger protein 113A
SEC23B Sec23 homolog B (S. cerevisiae)
SELENBP1 selenium binding protein 1
SH3GLB2 SH3-domain GRB2-like endophilin B2
SIL1 SIL1 nucleotide exchange factor
SKA3 spindle and kinetochore associated complex subunit 3
SMAP2 small ArfGAP2
SND1 staphylococcal nuclease and tudor domain containing 1
SOD1 superoxide dismutase 1, soluble
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae)
SPTY2D1 SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)
SRM spermidine synthase
SSR1 signal sequence receptor, alpha
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
SSR4 signal sequence receptor, delta
STS steroid sulfatase (microsomal), isozyme S
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TKFC triokinase/FMN cyclase
TMCO3 transmembrane and coiled-coil domains 3
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TSLIG1 tRNA splicing ligase complex subunit 1
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum)
UBA5 ubiquitin-like modifier activating enzyme 5
UBE2L6 ubiquitin-conjugating enzyme E2L 6
USP24 ubiquitin specific peptidase 24
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
VARS valyl-tRNA synthetase
VIP vasoactive intestinal peptide
VTN vitronectin

Symbol Name
AAK1 AP2 associated kinase 1
ACTN4 actinin, alpha 4
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
ATRN attractin
BCL10 B-cell CLL/lymphoma 10
BCL2L13 BCL2-like 13 (apoptosis facilitator)
BCL7B B-cell CLL/lymphoma 7B
BCR breakpoint cluster region
CBX1 chromobox homolog 1
CCDC9 coiled-coil domain containing 9
CENPQ centromere protein Q
COMMD4 COMM domain containing 4
CORO1B coronin, actin binding protein, 1B
CREB1 cAMP responsive element binding protein 1
CRELD2 cysteine-rich with EGF-like domains 2
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTTN cortactin
DBN1 drebrin 1
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial
ERH enhancer of rudimentary homolog (Drosophila)
FBXO30 F-box protein 30
FDX1 ferredoxin 1
FNDC3A fibronectin type III domain containing 3A
GFAP glial fibrillary acidic protein
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4
GNG12 guanine nucleotide binding protein (G protein), gamma 12
GRSF1 G-rich RNA sequence binding factor 1
GULP1 GULP, engulfment adaptor PTB domain containing 1
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3
HNRNPLL heterogeneous nuclear ribonucleoprotein L-like
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1
ILVBL ilvB (bacterial acetolactate synthase)-like
INF2 inverted formin, FH2 and WH2 domain containing
INO80B INO80 complex subunit B
INTS5 integrator complex subunit 5
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITM2C integral membrane protein 2C
KAT7 K(lysine) acetyltransferase 7
KIAA1522 KIAA1522
KPNA3 karyopherin alpha 3 (importin alpha 4)
LACTB lactamase, beta
LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
LEO1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
LOC100131158 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa pseudogene
LOC105375028 uncharacterized LOC105375028
MALSU1 mitochondrial assembly of ribosomal large subunit 1
MEF2B myocyte enhancer factor 2B
METTL3 methyltransferase like 3
MFAP1 microfibrillar-associated protein 1
MOB4 MOB family member 4, phocein
MRPL20 mitochondrial ribosomal protein L20
MTA1 metastasis associated 1
MXRA7 matrix-remodelling associated 7
NCAPH2 non-SMC condensin II complex, subunit H2
NFRKB nuclear factor related to kappaB binding protein
OVCA2 ovarian tumor suppressor candidate 2
PDLIM4 PDZ and LIM domain 4
PHF14 PHD finger protein 14
PNMA1 paraneoplastic Ma antigen 1
POLDIP3 polymerase (DNA-directed), delta interacting protein 3
PRAF2 PRA1 domain family, member 2
PRRC2B proline-rich coiled-coil 2B
RAB18 RAB18, member RAS oncogene family
RAB5C RAB5C, member RAS oncogene family
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RBBP6 retinoblastoma binding protein 6
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RHOG ras homolog family member G
RTTN rotatin
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SNX18 sorting nexin 18
SORCS2 sortilin-related VPS10 domain containing receptor 2
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites
STIM2 stromal interaction molecule 2
STRN3 striatin, calmodulin binding protein 3
STX18 syntaxin 18
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa
TMSB10 thymosin beta 10
TMTC3 transmembrane and tetratricopeptide repeat containing 3
TOR1A torsin family 1, member A (torsin A)
TYMS thymidylate synthetase
UBE2T ubiquitin-conjugating enzyme E2T
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1
URI1 URI1, prefoldin-like chaperone
URM1 ubiquitin related modifier 1
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C
VTI1B vesicle transport through interaction with t-SNAREs 1B
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
XXYLT1 xyloside xylosyltransferase 1
ZC3H14 zinc finger CCCH-type containing 14
ZFR zinc finger RNA binding protein
ZMYM3 zinc finger, MYM-type 3
ZNF326 zinc finger protein 326