RPMI-8866 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
Description Human B lymphoid cell line, established from the peripheral blood of a 51-year-old American woman with chronic myelogenous leukemia in May 1966. (BRENDA Tissue and Enzyme Source Ontology, BTO_0004206)
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Genes

575 genes with high or low expression in RPMI-8866 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 3.48016
PAOX polyamine oxidase (exo-N4-amino) 3.47676
PPCDC phosphopantothenoylcysteine decarboxylase 3.43261
PGPEP1 pyroglutamyl-peptidase I 3.32871
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2 3.27762
SNN stannin 2.97687
CCDC28B coiled-coil domain containing 28B 2.95983
SNX4 sorting nexin 4 2.95428
DTX4 deltex 4, E3 ubiquitin ligase 2.89624
PILRA paired immunoglobin-like type 2 receptor alpha 2.833
EBI3 Epstein-Barr virus induced 3 2.79199
MFN1 mitofusin 1 2.78911
MR1 major histocompatibility complex, class I-related 2.78104
PTAFR platelet-activating factor receptor 2.77805
CD83 CD83 molecule 2.75611
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) 2.73971
CRYZ crystallin, zeta (quinone reductase) 2.71037
UNC119 unc-119 homolog (C. elegans) 2.70978
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 2.70247
NBN nibrin 2.69778
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 2.69214
CHMP4A charged multivesicular body protein 4A 2.6861
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides 2.68021
HYAL4 hyaluronoglucosaminidase 4 2.67903
RASSF4 Ras association (RalGDS/AF-6) domain family member 4 2.67493
CEPT1 choline/ethanolamine phosphotransferase 1 2.64721
RAB9A RAB9A, member RAS oncogene family 2.64492
CCR7 chemokine (C-C motif) receptor 7 2.60103
NCF2 neutrophil cytosolic factor 2 2.57343
IL12B interleukin 12B 2.56471
ZBTB10 zinc finger and BTB domain containing 10 2.54653
CD40 CD40 molecule, TNF receptor superfamily member 5 2.52491
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 2.51899
REPS2 RALBP1 associated Eps domain containing 2 2.5166
AIRE autoimmune regulator 2.49835
TANK TRAF family member-associated NFKB activator 2.48479
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 2.472
CLIC2 chloride intracellular channel 2 2.47142
IL27RA interleukin 27 receptor, alpha 2.46988
ZDHHC18 zinc finger, DHHC-type containing 18 2.46536
UPB1 ureidopropionase, beta 2.45256
TRAF1 TNF receptor-associated factor 1 2.42334
KLK1 kallikrein 1 2.40709
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 2.40127
CBX6 chromobox homolog 6 2.40078
SEPHS2 selenophosphate synthetase 2 2.39775
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 2.38104
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 2.37627
ANO10 anoctamin 10 2.35396
OFD1 oral-facial-digital syndrome 1 2.33188
ZNF518A zinc finger protein 518A 2.32419
ASL argininosuccinate lyase 2.31084
EPHB1 EPH receptor B1 2.29643
PLEK pleckstrin 2.27963
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 2.26233
UBE2Z ubiquitin-conjugating enzyme E2Z 2.26079
GUCY1B3 guanylate cyclase 1, soluble, beta 3 2.24876
LOC644450 uncharacterized LOC644450 2.24203
NCK1 NCK adaptor protein 1 2.23773
CD86 CD86 molecule 2.22999
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14 2.22798
SRBD1 S1 RNA binding domain 1 2.22187
IL21R interleukin 21 receptor 2.21429
ASPA aspartoacylase 2.19992
BCL2 B-cell CLL/lymphoma 2 2.19892
TFEB transcription factor EB 2.19462
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 2.18602
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 2.16827
TYK2 tyrosine kinase 2 2.16247
ZNF267 zinc finger protein 267 2.15552
PLA2G2D phospholipase A2, group IID 2.14956
OLAH oleoyl-ACP hydrolase 2.13996
MAP3K14 mitogen-activated protein kinase kinase kinase 14 2.13797
POMP proteasome maturation protein 2.13249
ISCU iron-sulfur cluster assembly enzyme 2.12912
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 2.12007
DUSP22 dual specificity phosphatase 22 2.11809
PLD1 phospholipase D1, phosphatidylcholine-specific 2.10127
YEATS2 YEATS domain containing 2 2.09844
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 2.08955
MED18 mediator complex subunit 18 2.07326
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled 2.07191
RHOG ras homolog family member G 2.06823
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle) 2.06817
LYN LYN proto-oncogene, Src family tyrosine kinase 2.06517
IRF5 interferon regulatory factor 5 2.06146
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 2.05978
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 2.058
TRIM26 tripartite motif containing 26 2.053
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 2.04896
SCARB1 scavenger receptor class B, member 1 2.04747
UBXN7 UBX domain protein 7 2.04493
BAX BCL2-associated X protein 2.04489
RABGGTA Rab geranylgeranyltransferase, alpha subunit 2.03992
FLOT2 flotillin 2 2.03235
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 2.03219
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 2.02638
KCNK5 potassium channel, two pore domain subfamily K, member 5 2.02175
IQSEC1 IQ motif and Sec7 domain 1 2.01372
CTSO cathepsin O 2.01294
SPIB Spi-B transcription factor (Spi-1/PU.1 related) 1.99846
GM2A GM2 ganglioside activator 1.99492
KLHL24 kelch-like family member 24 1.99376
GADD45B growth arrest and DNA-damage-inducible, beta 1.99193
USP9X ubiquitin specific peptidase 9, X-linked 1.98985
CYLD cylindromatosis (turban tumor syndrome) 1.98942
GHR growth hormone receptor 1.98749
GEMIN8 gem (nuclear organelle) associated protein 8 1.98693
SNX11 sorting nexin 11 1.98415
FAS Fas cell surface death receptor 1.98341
IER5 immediate early response 5 1.9816
PASK PAS domain containing serine/threonine kinase 1.97853
SCYL3 SCY1-like 3 (S. cerevisiae) 1.97637
MYOZ1 myozenin 1 1.97336
IL2RG interleukin 2 receptor, gamma 1.95776
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 1.95557
IGFLR1 IGF-like family receptor 1 1.95462
TRPV2 transient receptor potential cation channel, subfamily V, member 2 1.95043
PLA1A phospholipase A1 member A 1.92489
IFNGR1 interferon gamma receptor 1 1.91893
TRAPPC2 trafficking protein particle complex 2 1.91466
ZBTB32 zinc finger and BTB domain containing 32 1.91209
CEP135 centrosomal protein 135kDa 1.91173
TTF2 transcription termination factor, RNA polymerase II 1.90851
SHOC2 soc-2 suppressor of clear homolog (C. elegans) 1.90213
ARF6 ADP-ribosylation factor 6 1.89209
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8 1.89143
PTK2B protein tyrosine kinase 2 beta 1.88887
ZNF688 zinc finger protein 688 1.88794
RFX1 regulatory factor X, 1 (influences HLA class II expression) 1.88416
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 1.88245
ADH6 alcohol dehydrogenase 6 (class V) 1.8801
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 1.87903
LNPEP leucyl/cystinyl aminopeptidase 1.87514
ATF5 activating transcription factor 5 1.8707
NBEAL2 neurobeachin-like 2 1.86879
ZC3H7A zinc finger CCCH-type containing 7A 1.86778
GPN2 GPN-loop GTPase 2 1.86366
FAM90A1 family with sequence similarity 90, member A1 1.86093
SSTR2 somatostatin receptor 2 1.8599
ICAM1 intercellular adhesion molecule 1 1.85803
CD101 CD101 molecule 1.85457
POPDC2 popeye domain containing 2 1.85336
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 1.85076
CREB5 cAMP responsive element binding protein 5 1.84285
CLEC16A C-type lectin domain family 16, member A 1.82958
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta 1.82838
SEPT8 septin 8 1.82589
ADI1 acireductone dioxygenase 1 1.82345
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 1.82129
CTH cystathionine gamma-lyase 1.82088
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 1.81698
SLC39A9 solute carrier family 39, member 9 1.81684
LGTN ligatin 1.81172
DNAI2 dynein, axonemal, intermediate chain 2 1.80605
SPN sialophorin 1.80541
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 1.80426
SYF2 SYF2 pre-mRNA-splicing factor 1.8037
RNGTT RNA guanylyltransferase and 5'-phosphatase 1.79129
SF3A1 splicing factor 3a, subunit 1, 120kDa 1.78869
ZNF189 zinc finger protein 189 1.78859
PTP4A3 protein tyrosine phosphatase type IVA, member 3 1.7881
MCTP1 multiple C2 domains, transmembrane 1 1.78654
GTPBP2 GTP binding protein 2 1.77512
SOCS1 suppressor of cytokine signaling 1 1.77269
STAT5A signal transducer and activator of transcription 5A 1.77235
PRRC2C proline-rich coiled-coil 2C 1.77216
TRIAP1 TP53 regulated inhibitor of apoptosis 1 1.76974
XPO6 exportin 6 1.769
COL9A2 collagen, type IX, alpha 2 1.76328
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 1.76131
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 1.75751
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 1.75686
LY75 lymphocyte antigen 75 1.75511
DTNB dystrobrevin, beta 1.74937
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.74406
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 1.74356
ASCC1 activating signal cointegrator 1 complex subunit 1 1.74314
MRPL16 mitochondrial ribosomal protein L16 1.73375
TRA2B transformer 2 beta homolog (Drosophila) 1.73314
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 1.73267
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 1.73205
BATF basic leucine zipper transcription factor, ATF-like 1.72772
CD70 CD70 molecule 1.72418
NFE2L1 nuclear factor, erythroid 2-like 1 1.72142
ZMAT3 zinc finger, matrin-type 3 1.71553
LPGAT1 lysophosphatidylglycerol acyltransferase 1 1.71534
STXBP2 syntaxin binding protein 2 1.7129
CDC42SE1 CDC42 small effector 1 1.71272
SLAMF7 SLAM family member 7 1.70879
NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa 1.70478
SYT17 synaptotagmin XVII 1.70437
ANXA6 annexin A6 1.70371
MTMR8 myotubularin related protein 8 1.70308
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.70231
BAGE B melanoma antigen 1.7017
PSIP1 PC4 and SFRS1 interacting protein 1 1.70095
BTG1 B-cell translocation gene 1, anti-proliferative 1.69238
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase 1.69056
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1 1.68887
USP12 ubiquitin specific peptidase 12 1.68867
DNASE1L3 deoxyribonuclease I-like 3 1.68546
SLAMF1 signaling lymphocytic activation molecule family member 1 1.6729
XPC xeroderma pigmentosum, complementation group C 1.67084
DCTPP1 dCTP pyrophosphatase 1 1.66831
CIITA class II, major histocompatibility complex, transactivator 1.66782
KIF3A kinesin family member 3A 1.66691
BATF3 basic leucine zipper transcription factor, ATF-like 3 1.66685
TRAF3 TNF receptor-associated factor 3 1.66395
ALPK1 alpha-kinase 1 1.64965
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A 1.64916
DHRS1 dehydrogenase/reductase (SDR family) member 1 1.64529
ZFR zinc finger RNA binding protein 1.64371
KLHL18 kelch-like family member 18 1.64218
GHITM growth hormone inducible transmembrane protein 1.64031
HAAO 3-hydroxyanthranilate 3,4-dioxygenase 1.6397
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 1.63861
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 1.63256
LTA lymphotoxin alpha 1.62907
ENO3 enolase 3 (beta, muscle) 1.62808
P2RY10 purinergic receptor P2Y, G-protein coupled, 10 1.6242
GGNBP2 gametogenetin binding protein 2 1.62405
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa 1.62084
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1 1.61655
RBM19 RNA binding motif protein 19 1.61571
NADK NAD kinase 1.61439
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B) 1.61326
ISOC1 isochorismatase domain containing 1 1.61263
MAP3K4 mitogen-activated protein kinase kinase kinase 4 1.61078
DDB2 damage-specific DNA binding protein 2, 48kDa 1.61038
RGS14 regulator of G-protein signaling 14 1.60811
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.60737
PARK7 parkinson protein 7 1.6026
RUNX3 runt-related transcription factor 3 1.60148
FNBP1 formin binding protein 1 1.60139
ACKR3 atypical chemokine receptor 3 1.59914
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10 1.59892
ADORA2A adenosine A2a receptor 1.596
DUSP2 dual specificity phosphatase 2 1.59079
IL16 interleukin 16 1.58673
COLEC10 collectin sub-family member 10 (C-type lectin) 1.58613
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 1.58421
SSX1 synovial sarcoma, X breakpoint 1 1.58374
DTX2 deltex 2, E3 ubiquitin ligase 1.58297
GPX4 glutathione peroxidase 4 1.58234
TLE3 transducin-like enhancer of split 3 1.57899
U2SURP U2 snRNP-associated SURP domain containing 1.57702
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) 1.57564
THUMPD1 THUMP domain containing 1 1.57222
KHNYN KH and NYN domain containing 1.57184
SYMPK symplekin 1.57053
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 1.56742
BTN2A2 butyrophilin, subfamily 2, member A2 1.56727
LHX2 LIM homeobox 2 1.56274
MPC1 mitochondrial pyruvate carrier 1 1.56136
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.56028
CLC Charcot-Leyden crystal galectin 1.56015
ARHGAP17 Rho GTPase activating protein 17 1.56006
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 1.55949
IL7 interleukin 7 1.55721
EIF4A3 eukaryotic translation initiation factor 4A3 1.55671
DCAF11 DDB1 and CUL4 associated factor 11 1.55167
TAPBP TAP binding protein (tapasin) 1.55155
GPSM3 G-protein signaling modulator 3 1.5509
EIF1 eukaryotic translation initiation factor 1 1.55
SIRPG signal-regulatory protein gamma 1.54919
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I 1.54915
RREB1 ras responsive element binding protein 1 1.54621
EDF1 endothelial differentiation-related factor 1 1.54603
ARHGAP26 Rho GTPase activating protein 26 1.54583
TGM5 transglutaminase 5 1.54556
C8G complement component 8, gamma polypeptide 1.54398
INSL6 insulin-like 6 1.54044
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.5376
TRAC T cell receptor alpha constant 1.53546
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 1.53524
EIF4E2 eukaryotic translation initiation factor 4E family member 2 1.53451
MYH7B myosin, heavy chain 7B, cardiac muscle, beta 1.53393
CHERP calcium homeostasis endoplasmic reticulum protein 1.53323
CD300A CD300a molecule 1.53265
SCLY selenocysteine lyase 1.53255
IGKC immunoglobulin kappa constant 1.5294
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 1.52701
SAFB scaffold attachment factor B 1.525
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 1.5236
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18 1.52305
ADAM3A ADAM metallopeptidase domain 3A (pseudogene) 1.51919
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1 1.51517
NUP98 nucleoporin 98kDa 1.51339
EPS15 epidermal growth factor receptor pathway substrate 15 1.51232
NIPA2 non imprinted in Prader-Willi/Angelman syndrome 2 1.50737
AKAP13 A kinase (PRKA) anchor protein 13 1.49992
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 1.49916
TRAFD1 TRAF-type zinc finger domain containing 1 1.49816
RPS27L ribosomal protein S27-like 1.49753
CD58 CD58 molecule 1.49665
CFLAR CASP8 and FADD-like apoptosis regulator 1.49607
DENND2D DENN/MADD domain containing 2D 1.49054
HMGN3 high mobility group nucleosomal binding domain 3 1.48798
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14 1.48755
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 1.48653
PITPNB phosphatidylinositol transfer protein, beta 1.48498
THPO thrombopoietin 1.48483
MAPK11 mitogen-activated protein kinase 11 1.48349
CCR10 chemokine (C-C motif) receptor 10 1.48077
ACTR8 ARP8 actin-related protein 8 homolog (yeast) 1.47877
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.47872
QKI QKI, KH domain containing, RNA binding 1.47831
RORA RAR-related orphan receptor A 1.47706
PIAS1 protein inhibitor of activated STAT, 1 1.47605
LMOD1 leiomodin 1 (smooth muscle) 1.47175
MTRF1L mitochondrial translational release factor 1-like 1.46865
WARS tryptophanyl-tRNA synthetase 1.46792
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 1.46625
CD80 CD80 molecule 1.46538
KLHL29 kelch-like family member 29 1.46478
DEFA6 defensin, alpha 6, Paneth cell-specific 1.46469
LY86 lymphocyte antigen 86 1.46462
CECR1 cat eye syndrome chromosome region, candidate 1 1.46347
CLEC3B C-type lectin domain family 3, member B 1.46346
IL17RB interleukin 17 receptor B 1.46234
TRIM5 tripartite motif containing 5 1.46074
PCDHA10 protocadherin alpha 10 1.45979
CCND2 cyclin D2 1.45977
CLEC4M C-type lectin domain family 4, member M 1.45939
EMID1 EMI domain containing 1 1.45556
ARG1 arginase 1 1.45086
MED26 mediator complex subunit 26 1.44955
CCL22 chemokine (C-C motif) ligand 22 1.44701
CDC14A cell division cycle 14A 1.44643
PELI1 pellino E3 ubiquitin protein ligase 1 1.44239
COPB1 coatomer protein complex, subunit beta 1 1.44168
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1 1.43568
RAD21 RAD21 homolog (S. pombe) 1.43503
MAP3K5 mitogen-activated protein kinase kinase kinase 5 1.43189
CHST10 carbohydrate sulfotransferase 10 1.43173
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 1.42919
INHBE inhibin, beta E 1.42854
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 1.4273
RBM14 RNA binding motif protein 14 1.42554
MSC musculin 1.42453
LONP1 lon peptidase 1, mitochondrial 1.42446
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) 1.42379
TLR1 toll-like receptor 1 1.42288
MCM3AP minichromosome maintenance complex component 3 associated protein 1.42274
PLAC1 placenta-specific 1 1.42272
KLF13 Kruppel-like factor 13 1.4218
EWSR1 EWS RNA-binding protein 1 1.4212
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 1.42043
GOLIM4 golgi integral membrane protein 4 1.41774
MTMR4 myotubularin related protein 4 1.41701
UVRAG UV radiation resistance associated 1.4166

low expression

Symbol Name Standardized Value
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -3.53725
ENDOG endonuclease G -3.53725
ZNF26 zinc finger protein 26 -3.53725
JADE3 jade family PHD finger 3 -3.53725
BZW2 basic leucine zipper and W2 domains 2 -3.53725
H1FX H1 histone family, member X -3.53721
TSC22D1 TSC22 domain family, member 1 -3.44823
QDPR quinoid dihydropteridine reductase -3.02952
PCYOX1 prenylcysteine oxidase 1 -2.88076
CTSB cathepsin B -2.84494
RAB4A RAB4A, member RAS oncogene family -2.80802
ZNF44 zinc finger protein 44 -2.78068
CTNNBIP1 catenin, beta interacting protein 1 -2.76343
MARCH3 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase -2.74816
SCARB2 scavenger receptor class B, member 2 -2.6529
PEMT phosphatidylethanolamine N-methyltransferase -2.60649
NDFIP1 Nedd4 family interacting protein 1 -2.60631
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 -2.60135
ITM2B integral membrane protein 2B -2.60097
NFIL3 nuclear factor, interleukin 3 regulated -2.57867
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 -2.49812
JAK1 Janus kinase 1 -2.45974
ZNF510 zinc finger protein 510 -2.45704
PDIA4 protein disulfide isomerase family A, member 4 -2.45461
FOXN3 forkhead box N3 -2.43553
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase -2.42616
ADCY9 adenylate cyclase 9 -2.398
GLA galactosidase, alpha -2.39643
IPO7 importin 7 -2.39513
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1 -2.3931
PLA2R1 phospholipase A2 receptor 1, 180kDa -2.37936
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 -2.37465
SEPW1 selenoprotein W, 1 -2.3586
REXO2 RNA exonuclease 2 -2.34718
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) -2.33774
COBLL1 cordon-bleu WH2 repeat protein-like 1 -2.33285
TRIM23 tripartite motif containing 23 -2.33115
NEK3 NIMA-related kinase 3 -2.3053
IGF1R insulin-like growth factor 1 receptor -2.30514
CAPN2 calpain 2, (m/II) large subunit -2.28923
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme -2.26539
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast) -2.24957
TGFB3 transforming growth factor, beta 3 -2.24176
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 -2.23326
RAB40B RAB40B, member RAS oncogene family -2.23267
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) -2.23194
SCAMP1 secretory carrier membrane protein 1 -2.2253
DUSP3 dual specificity phosphatase 3 -2.21322
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 -2.21152
TUBD1 tubulin, delta 1 -2.21108
MYO1B myosin IB -2.19606
CHPT1 choline phosphotransferase 1 -2.19566
PPIC peptidylprolyl isomerase C (cyclophilin C) -2.19289
TEX2 testis expressed 2 -2.17847
SYNJ2 synaptojanin 2 -2.15912
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) -2.15748
MANF mesencephalic astrocyte-derived neurotrophic factor -2.15466
ANKMY2 ankyrin repeat and MYND domain containing 2 -2.15465
CENPQ centromere protein Q -2.15366
NBPF10 neuroblastoma breakpoint family, member 10 -2.15245
TMEM185B transmembrane protein 185B -2.13611
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 -2.13535
ADSS adenylosuccinate synthase -2.11924
CORO1B coronin, actin binding protein, 1B -2.11794
CKB creatine kinase, brain -2.10915
ADK adenosine kinase -2.10862
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -2.09645
SALL2 spalt-like transcription factor 2 -2.09479
MGA MGA, MAX dimerization protein -2.09307
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II -2.07573
TMEM45A transmembrane protein 45A -2.07562
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -2.05649
AHI1 Abelson helper integration site 1 -2.05349
FUCA1 fucosidase, alpha-L- 1, tissue -2.04934
WLS wntless Wnt ligand secretion mediator -2.04885
PCDH9 protocadherin 9 -2.04197
MATN3 matrilin 3 -2.03687
PRDX6 peroxiredoxin 6 -2.00703
ARHGAP5 Rho GTPase activating protein 5 -1.99669
ST7L suppression of tumorigenicity 7 like -1.99184
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 -1.98162
RHOB ras homolog family member B -1.97579
MSX1 msh homeobox 1 -1.96979
CDRT1 CMT1A duplicated region transcript 1 -1.95455
SCRN3 secernin 3 -1.95166
RGS2 regulator of G-protein signaling 2 -1.93027
HDAC7 histone deacetylase 7 -1.9186
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -1.91844
PTPRS protein tyrosine phosphatase, receptor type, S -1.91383
ZFP69B ZFP69 zinc finger protein B -1.90662
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2 -1.90102
NOTCH2 notch 2 -1.88931
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2 -1.88409
GPSM2 G-protein signaling modulator 2 -1.86906
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) -1.86902
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1 -1.8575
LTA4H leukotriene A4 hydrolase -1.84837
RNF144A ring finger protein 144A -1.84141
SSFA2 sperm specific antigen 2 -1.83919
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 -1.83846
IMPACT impact RWD domain protein -1.82221
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 -1.8118
HEBP1 heme binding protein 1 -1.81062
APH1B APH1B gamma secretase subunit -1.80793
VAT1 vesicle amine transport 1 -1.80543
OSBPL1A oxysterol binding protein-like 1A -1.80346
FAM63A family with sequence similarity 63, member A -1.80178
RPN1 ribophorin I -1.79316
ACVR1B activin A receptor, type IB -1.78696
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) -1.78588
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 -1.77995
SLC35F5 solute carrier family 35, member F5 -1.77824
INHA inhibin, alpha -1.77329
KLHL12 kelch-like family member 12 -1.77275
MPI mannose phosphate isomerase -1.76251
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding) -1.76027
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 -1.75979
PREP prolyl endopeptidase -1.7575
CALHM2 calcium homeostasis modulator 2 -1.75464
ZFYVE21 zinc finger, FYVE domain containing 21 -1.7517
PTCH1 patched 1 -1.74876
GNAQ guanine nucleotide binding protein (G protein), q polypeptide -1.74518
NDRG1 N-myc downstream regulated 1 -1.73831
ASB13 ankyrin repeat and SOCS box containing 13 -1.73673
CENPN centromere protein N -1.73257
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 -1.71962
NR2C1 nuclear receptor subfamily 2, group C, member 1 -1.71899
SPHAR S-phase response (cyclin related) -1.71323
PICK1 protein interacting with PRKCA 1 -1.70772
NOV nephroblastoma overexpressed -1.70292
TRIM36 tripartite motif containing 36 -1.69545
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B -1.69356
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13 -1.69216
TECR trans-2,3-enoyl-CoA reductase -1.68562
ARSD arylsulfatase D -1.68329
PODXL podocalyxin-like -1.67757
CERS2 ceramide synthase 2 -1.67719
PRKD3 protein kinase D3 -1.67538
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 -1.6685
SPHK1 sphingosine kinase 1 -1.66728
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa -1.65278
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1 -1.65178
SLC35B1 solute carrier family 35, member B1 -1.65155
ZW10 zw10 kinetochore protein -1.64706
BTG3 BTG family, member 3 -1.63311
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) -1.63102
BMP8B bone morphogenetic protein 8b -1.62954
AJAP1 adherens junctions associated protein 1 -1.6235
PDIA5 protein disulfide isomerase family A, member 5 -1.61964
OAT ornithine aminotransferase -1.6148
HPCAL1 hippocalcin-like 1 -1.6112
ALDH4A1 aldehyde dehydrogenase 4 family, member A1 -1.60705
HSPB1 heat shock 27kDa protein 1 -1.60661
KLF11 Kruppel-like factor 11 -1.60495
RYR1 ryanodine receptor 1 (skeletal) -1.6037
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum) -1.5979
IL1RAP interleukin 1 receptor accessory protein -1.59422
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 -1.59101
SATB1 SATB homeobox 1 -1.58647
NME7 NME/NM23 family member 7 -1.58637
EZR ezrin -1.5857
PCDH7 protocadherin 7 -1.5849
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 -1.58461
GARNL3 GTPase activating Rap/RanGAP domain-like 3 -1.57823
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 -1.5773
EXOSC4 exosome component 4 -1.57347
LZTS3 leucine zipper, putative tumor suppressor family member 3 -1.56864
ZNF280D zinc finger protein 280D -1.56473
ZNF551 zinc finger protein 551 -1.56147
LEPR leptin receptor -1.561
OR2F2 olfactory receptor, family 2, subfamily F, member 2 -1.55423
ZNF204P zinc finger protein 204, pseudogene -1.55346
TRIP13 thyroid hormone receptor interactor 13 -1.54886
EMC1 ER membrane protein complex subunit 1 -1.54695
S100A6 S100 calcium binding protein A6 -1.54318
SDCCAG8 serologically defined colon cancer antigen 8 -1.5403
MRPL17 mitochondrial ribosomal protein L17 -1.53924
TXNRD1 thioredoxin reductase 1 -1.53492
CEBPD CCAAT/enhancer binding protein (C/EBP), delta -1.53043
TMEM144 transmembrane protein 144 -1.52734
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 -1.52228
ABLIM1 actin binding LIM protein 1 -1.52156
MECR mitochondrial trans-2-enoyl-CoA reductase -1.51634
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7 -1.51522
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 -1.51224
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 -1.51001
NUTF2 nuclear transport factor 2 -1.50222
SORD sorbitol dehydrogenase -1.50127
ZNF32 zinc finger protein 32 -1.5008
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 -1.49751
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F -1.49542
ILVBL ilvB (bacterial acetolactate synthase)-like -1.49342
CEP170B centrosomal protein 170B -1.49274
TMEM106B transmembrane protein 106B -1.48661
WDFY3 WD repeat and FYVE domain containing 3 -1.48628
ZNF443 zinc finger protein 443 -1.47628
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -1.4757
EPHB2 EPH receptor B2 -1.47544
CCNB1 cyclin B1 -1.47529
PGRMC2 progesterone receptor membrane component 2 -1.46947
ZNF83 zinc finger protein 83 -1.46906
OXR1 oxidation resistance 1 -1.46657
CERS6 ceramide synthase 6 -1.46242
STAMBPL1 STAM binding protein-like 1 -1.46016
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 -1.45681
SNIP1 Smad nuclear interacting protein 1 -1.45659
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic) -1.45482
IFI44 interferon-induced protein 44 -1.45469
RNF130 ring finger protein 130 -1.45441
ERBB2 erb-b2 receptor tyrosine kinase 2 -1.45377
DUSP6 dual specificity phosphatase 6 -1.45287
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) -1.44389
RABEPK Rab9 effector protein with kelch motifs -1.44294
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) -1.44137
ARL4A ADP-ribosylation factor-like 4A -1.43986
HRASLS HRAS-like suppressor -1.43698
PPIH peptidylprolyl isomerase H (cyclophilin H) -1.43618
PCNXL2 pecanex-like 2 (Drosophila) -1.43155
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) -1.42841
HSBP1 heat shock factor binding protein 1 -1.42423
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 -1.42137
DIXDC1 DIX domain containing 1 -1.42006
ETV5 ets variant 5 -1.41762