| Dataset | MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | gene perturbation identified as [gene symbol]_[perturbation or condition] (Molecular Signatures Database) |
| External Link | http://www.broadinstitute.org/gsea/msigdb/cards/RPS14_DN.V1_UP |
| Similar Terms | |
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378 genes differentially expressed following the RPS14_DN.V1 gene perturbation from the MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations dataset.
| Symbol | Name |
|---|---|
| ACTA2 | actin, alpha 2, smooth muscle, aorta |
| ADA | adenosine deaminase |
| ADAMDEC1 | ADAM-like, decysin 1 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 |
| ADRA2A | adrenoceptor alpha 2A |
| AIF1 | allograft inflammatory factor 1 |
| ALCAM | activated leukocyte cell adhesion molecule |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) |
| ANPEP | alanyl (membrane) aminopeptidase |
| ANXA3 | annexin A3 |
| ANXA6 | annexin A6 |
| ARHGAP25 | Rho GTPase activating protein 25 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 |
| ARL4C | ADP-ribosylation factor-like 4C |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| ATP8B4 | ATPase, class I, type 8B, member 4 |
| AZU1 | azurocidin 1 |
| BCL2A1 | BCL2-related protein A1 |
| BCL6 | B-cell CLL/lymphoma 6 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BST1 | bone marrow stromal cell antigen 1 |
| C3AR1 | complement component 3a receptor 1 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit |
| CALB1 | calbindin 1, 28kDa |
| CAPG | capping protein (actin filament), gelsolin-like |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CCL1 | chemokine (C-C motif) ligand 1 |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CCNA1 | cyclin A1 |
| CD14 | CD14 molecule |
| CD300A | CD300a molecule |
| CD69 | CD69 molecule |
| CD9 | CD9 molecule |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 |
| CDCP1 | CUB domain containing protein 1 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 |
| CECR1 | cat eye syndrome chromosome region, candidate 1 |
| CELA2A | chymotrypsin-like elastase family, member 2A |
| CLEC2B | C-type lectin domain family 2, member B |
| CLEC5A | C-type lectin domain family 5, member A |
| CLEC7A | C-type lectin domain family 7, member A |
| COLEC12 | collectin sub-family member 12 |
| CPM | carboxypeptidase M |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) |
| CROT | carnitine O-octanoyltransferase |
| CRTAM | cytotoxic and regulatory T cell molecule |
| CSTA | cystatin A (stefin A) |
| CTSG | cathepsin G |
| CTSH | cathepsin H |
| CTSS | cathepsin S |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| CYSLTR1 | cysteinyl leukotriene receptor 1 |
| DCN | decorin |
| DMXL2 | Dmx-like 2 |
| DNAJC22 | DnaJ (Hsp40) homolog, subfamily C, member 22 |
| EGR3 | early growth response 3 |
| ELANE | elastase, neutrophil expressed |
| EMP1 | epithelial membrane protein 1 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| EPS8L2 | EPS8-like 2 |
| EVI2A | ecotropic viral integration site 2A |
| EVI2B | ecotropic viral integration site 2B |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| F5 | coagulation factor V (proaccelerin, labile factor) |
| FBN2 | fibrillin 2 |
| FLVCR2 | feline leukemia virus subgroup C cellular receptor family, member 2 |
| FRY | furry homolog (Drosophila) |
| FUCA1 | fucosidase, alpha-L- 1, tissue |
| GDF15 | growth differentiation factor 15 |
| GFI1 | growth factor independent 1 transcription repressor |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GNB5 | guanine nucleotide binding protein (G protein), beta 5 |
| GPNMB | glycoprotein (transmembrane) nmb |
| GPR137B | G protein-coupled receptor 137B |
| GPR183 | G protein-coupled receptor 183 |
| HCK | HCK proto-oncogene, Src family tyrosine kinase |
| HESX1 | HESX homeobox 1 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha |
| HLA-DMB | major histocompatibility complex, class II, DM beta |
| HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
| HLA-DRB4 | major histocompatibility complex, class II, DR beta 4 |
| HLA-DRB6 | major histocompatibility complex, class II, DR beta 6 (pseudogene) |
| ICAM3 | intercellular adhesion molecule 3 |
| IFI16 | interferon, gamma-inducible protein 16 |
| IGFBP7 | insulin-like growth factor binding protein 7 |
| IGSF6 | immunoglobulin superfamily, member 6 |
| IL1B | interleukin 1, beta |
| IL1RAP | interleukin 1 receptor accessory protein |
| ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) |
| ITGAX | integrin, alpha X (complement component 3 receptor 4 subunit) |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
| JAG1 | jagged 1 |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 |
| KCTD12 | potassium channel tetramerization domain containing 12 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| KYNU | kynureninase |
| LECT2 | leukocyte cell-derived chemotaxin 2 |
| LINC00461 | long intergenic non-protein coding RNA 461 |
| LPXN | leupaxin |
| LST1 | leukocyte specific transcript 1 |
| LY75 | lymphocyte antigen 75 |
| LY86 | lymphocyte antigen 86 |
| LY96 | lymphocyte antigen 96 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog |
| MARCKS | myristoylated alanine-rich protein kinase C substrate |
| MDFIC | MyoD family inhibitor domain containing |
| MNDA | myeloid cell nuclear differentiation antigen |
| MPL | MPL proto-oncogene, thrombopoietin receptor |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
| MX1 | MX dynamin-like GTPase 1 |
| MX2 | MX dynamin-like GTPase 2 |
| MYO1F | myosin IF |
| NCF2 | neutrophil cytosolic factor 2 |
| NKG7 | natural killer cell granule protein 7 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| NYNRIN | NYN domain and retroviral integrase containing |
| P2RY14 | purinergic receptor P2Y, G-protein coupled, 14 |
| PADI2 | peptidyl arginine deiminase, type II |
| PDE4D | phosphodiesterase 4D, cAMP-specific |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PF4V1 | platelet factor 4 variant 1 |
| PID1 | phosphotyrosine interaction domain containing 1 |
| PILRA | paired immunoglobin-like type 2 receptor alpha |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
| PLAU | plasminogen activator, urokinase |
| PLK2 | polo-like kinase 2 |
| PMP2 | peripheral myelin protein 2 |
| POM121L9P | POM121 transmembrane nucleoporin-like 9, pseudogene |
| PRG3 | proteoglycan 3 |
| PROM1 | prominin 1 |
| PRTN3 | proteinase 3 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) |
| PTPN22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| PTPRG | protein tyrosine phosphatase, receptor type, G |
| PTPRO | protein tyrosine phosphatase, receptor type, O |
| PYCARD | PYD and CARD domain containing |
| RAB31 | RAB31, member RAS oncogene family |
| RASAL2 | RAS protein activator like 2 |
| RASGRP3 | RAS guanyl releasing protein 3 (calcium and DAG-regulated) |
| RBM47 | RNA binding motif protein 47 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
| RHOB | ras homolog family member B |
| RIN2 | Ras and Rab interactor 2 |
| RMST | rhabdomyosarcoma 2 associated transcript (non-protein coding) |
| SASH3 | SAM and SH3 domain containing 3 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit |
| SDC4 | syndecan 4 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D |
| SEPT10 | septin 10 |
| SESN1 | sestrin 1 |
| SFXN3 | sideroflexin 3 |
| SH2D2A | SH2 domain containing 2A |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) |
| SH3GL3 | SH3-domain GRB2-like 3 |
| SIRPA | signal-regulatory protein alpha |
| SLAMF8 | SLAM family member 8 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 |
| SMAD3 | SMAD family member 3 |
| SNTG1 | syntrophin, gamma 1 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 |
| SPP1 | secreted phosphoprotein 1 |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 |
| STX3 | syntaxin 3 |
| TAC3 | tachykinin 3 |
| TFEC | transcription factor EC |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TIGAR | TP53 induced glycolysis regulatory phosphatase |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
| TNFRSF10C | tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain |
| TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 |
| TRIM22 | tripartite motif containing 22 |
| TRIM36 | tripartite motif containing 36 |
| TYROBP | TYRO protein tyrosine kinase binding protein |
| VNN1 | vanin 1 |
| VWF | von Willebrand factor |
| ZMAT3 | zinc finger, matrin-type 3 |
| Symbol | Name |
|---|---|
| ACKR1 | atypical chemokine receptor 1 (Duffy blood group) |
| ADD2 | adducin 2 (beta) |
| ADGRA3 | adhesion G protein-coupled receptor A3 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 |
| AGFG2 | ArfGAP with FG repeats 2 |
| ALAD | aminolevulinate dehydratase |
| AOC2 | amine oxidase, copper containing 2 (retina-specific) |
| APOBEC3A | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A |
| APOOL | apolipoprotein O-like |
| ARHGAP11A | Rho GTPase activating protein 11A |
| ART4 | ADP-ribosyltransferase 4 (Dombrock blood group) |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ATAD2 | ATPase family, AAA domain containing 2 |
| ATP1B2 | ATPase, Na+/K+ transporting, beta 2 polypeptide |
| B3GALNT1 | beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) |
| BAG2 | BCL2-associated athanogene 2 |
| BAG3 | BCL2-associated athanogene 3 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic |
| BYSL | bystin-like |
| C10ORF2 | chromosome 10 open reading frame 2 |
| C14ORF132 | chromosome 14 open reading frame 132 |
| CA3 | carbonic anhydrase III |
| CAD | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase |
| CBS | cystathionine-beta-synthase |
| CCNB2 | cyclin B2 |
| CD320 | CD320 molecule |
| CDC20 | cell division cycle 20 |
| CDC6 | cell division cycle 6 |
| CDCA3 | cell division cycle associated 3 |
| CDR2 | cerebellar degeneration-related protein 2, 62kDa |
| CENPE | centromere protein E, 312kDa |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHST5 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 |
| CLCN4 | chloride channel, voltage-sensitive 4 |
| CNN3 | calponin 3, acidic |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 |
| COLEC11 | collectin sub-family member 11 |
| CRISP2 | cysteine-rich secretory protein 2 |
| CRMP1 | collapsin response mediator protein 1 |
| CYBRD1 | cytochrome b reductase 1 |
| DBH | dopamine beta-hydroxylase (dopamine beta-monooxygenase) |
| DDN | dendrin |
| DEPDC1 | DEP domain containing 1 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DOCK9 | dedicator of cytokinesis 9 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| E2F8 | E2F transcription factor 8 |
| ECT2 | epithelial cell transforming 2 |
| EIF2B3 | eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa |
| ELMO3 | engulfment and cell motility 3 |
| EMP2 | epithelial membrane protein 2 |
| ENG | endoglin |
| EPB41 | erythrocyte membrane protein band 4.1 |
| EPCAM | epithelial cell adhesion molecule |
| ERCC2 | excision repair cross-complementation group 2 |
| ERCC6L | excision repair cross-complementation group 6-like |
| ESPL1 | extra spindle pole bodies homolog 1 (S. cerevisiae) |
| EXO1 | exonuclease 1 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FBXO5 | F-box protein 5 |
| FICD | FIC domain containing |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| FZD5 | frizzled class receptor 5 |
| GAL | galanin/GMAP prepropeptide |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GCDH | glutaryl-CoA dehydrogenase |
| GEMIN4 | gem (nuclear organelle) associated protein 4 |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| GLRA2 | glycine receptor, alpha 2 |
| GPATCH4 | G patch domain containing 4 |
| GSTA4 | glutathione S-transferase alpha 4 |
| GTF2H4 | general transcription factor IIH, polypeptide 4, 52kDa |
| GUF1 | GUF1 GTPase homolog (S. cerevisiae) |
| HGH1 | HGH1 homolog (S. cerevisiae) |
| HMGN5 | high mobility group nucleosome binding domain 5 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IL15RA | interleukin 15 receptor, alpha |
| IL7 | interleukin 7 |
| INCENP | inner centromere protein antigens 135/155kDa |
| IPO4 | importin 4 |
| ISOC2 | isochorismatase domain containing 2 |
| KANK2 | KN motif and ankyrin repeat domains 2 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KIF15 | kinesin family member 15 |
| KIF20A | kinesin family member 20A |
| KIF23 | kinesin family member 23 |
| KIF2C | kinesin family member 2C |
| KIF5A | kinesin family member 5A |
| KLHL7 | kelch-like family member 7 |
| KRT13 | keratin 13, type I |
| LARS2 | leucyl-tRNA synthetase 2, mitochondrial |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LOC730101 | uncharacterized LOC730101 |
| LRRC20 | leucine rich repeat containing 20 |
| MACROD1 | MACRO domain containing 1 |
| MAMLD1 | mastermind-like domain containing 1 |
| MANEA | mannosidase, endo-alpha |
| MCM10 | minichromosome maintenance complex component 10 |
| MCM5 | minichromosome maintenance complex component 5 |
| MDM4 | MDM4, p53 regulator |
| MIPEP | mitochondrial intermediate peptidase |
| MKI67 | marker of proliferation Ki-67 |
| MRPL12 | mitochondrial ribosomal protein L12 |
| MRPS2 | mitochondrial ribosomal protein S2 |
| MRTO4 | mRNA turnover 4 homolog (S. cerevisiae) |
| MSH2 | mutS homolog 2 |
| MTPAP | mitochondrial poly(A) polymerase |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
| MYH10 | myosin, heavy chain 10, non-muscle |
| MYLIP | myosin regulatory light chain interacting protein |
| MYO19 | myosin XIX |
| MYOC | myocilin, trabecular meshwork inducible glucocorticoid response |
| NCAPH | non-SMC condensin I complex, subunit H |
| NDC1 | NDC1 transmembrane nucleoporin |
| NEFH | neurofilament, heavy polypeptide |
| NID2 | nidogen 2 (osteonidogen) |
| NLE1 | notchless homolog 1 (Drosophila) |
| NMU | neuromedin U |
| NOC3L | nucleolar complex associated 3 homolog (S. cerevisiae) |
| NUP155 | nucleoporin 155kDa |
| ORC1 | origin recognition complex, subunit 1 |
| PBK | PDZ binding kinase |
| PC | pyruvate carboxylase |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
| PCOLCE | procollagen C-endopeptidase enhancer |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PES1 | pescadillo ribosomal biogenesis factor 1 |
| PKLR | pyruvate kinase, liver and RBC |
| PLK1 | polo-like kinase 1 |
| POLD1 | polymerase (DNA directed), delta 1, catalytic subunit |
| PRC1 | protein regulator of cytokinesis 1 |
| PRMT3 | protein arginine methyltransferase 3 |
| PSAT1 | phosphoserine aminotransferase 1 |
| PYCR1 | pyrroline-5-carboxylate reductase 1 |
| RAP1GAP | RAP1 GTPase activating protein |
| RASIP1 | Ras interacting protein 1 |
| REPS2 | RALBP1 associated Eps domain containing 2 |
| RGS5 | regulator of G-protein signaling 5 |
| RPS28 | ribosomal protein S28 |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| S100A3 | S100 calcium binding protein A3 |
| SERHL | serine hydrolase-like (pseudogene) |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 |
| SHMT1 | serine hydroxymethyltransferase 1 (soluble) |
| SIRT4 | sirtuin 4 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC29A1 | solute carrier family 29 (equilibrative nucleoside transporter), member 1 |
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
| SLC31A1 | solute carrier family 31 (copper transporter), member 1 |
| SLC43A1 | solute carrier family 43 (amino acid system L transporter), member 1 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
| SPHK1 | sphingosine kinase 1 |
| SPTB | spectrin, beta, erythrocytic |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| SRM | spermidine synthase |
| SRR | serine racemase |
| SSSCA1 | Sjogren syndrome/scleroderma autoantigen 1 |
| STEAP3 | STEAP family member 3, metalloreductase |
| STMN2 | stathmin 2 |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| TBRG4 | transforming growth factor beta regulator 4 |
| TFAP2B | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
| TGM2 | transglutaminase 2 |
| THEM6 | thioesterase superfamily member 6 |
| TK1 | thymidine kinase 1, soluble |
| TLN2 | talin 2 |
| TLX2 | T-cell leukemia homeobox 2 |
| TMSB15A | thymosin beta 15a |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TRIM29 | tripartite motif containing 29 |
| TRIP13 | thyroid hormone receptor interactor 13 |
| TSPO2 | translocator protein 2 |
| TUBB2A | tubulin, beta 2A class IIa |
| TUBB2B | tubulin, beta 2B class IIb |
| TUBG1 | tubulin, gamma 1 |
| TUBGCP4 | tubulin, gamma complex associated protein 4 |
| TWISTNB | TWIST neighbor |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VARS | valyl-tRNA synthetase |
| ZC2HC1C | zinc finger, C2HC-type containing 1C |
| ZNF74 | zinc finger protein 74 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
| ZWILCH | zwilch kinetochore protein |
