RPS6KA3 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description ribosomal protein S6 kinase, 90kDa, polypeptide 3|This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in this gene have been associated with Coffin-Lowry syndrome (CLS). [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6197)
External Link https://ncbi.nlm.nih.gov/gene/6197
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Genes

499 genes differentially expressed following the RPS6KA3 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.0160018
S100A8 S100 calcium binding protein A8 0.0149402
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.0133266
S100A9 S100 calcium binding protein A9 0.0118196
AK4 adenylate kinase 4 0.0113334
BCL2A1 BCL2-related protein A1 0.0112832
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.0112589
FABP7 fatty acid binding protein 7, brain 0.0109507
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 0.010602
KRT23 keratin 23, type I 0.0105145
PITX3 paired-like homeodomain 3 0.0103816
CXCL14 chemokine (C-X-C motif) ligand 14 0.0100414
KRT5 keratin 5, type II 0.00997777
PRKD3 protein kinase D3 0.00985744
FABP4 fatty acid binding protein 4, adipocyte 0.00972143
CD200 CD200 molecule 0.00950911
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.0094621
SELL selectin L 0.00934504
GJA1 gap junction protein, alpha 1, 43kDa 0.00897832
RCN2 reticulocalbin 2, EF-hand calcium binding domain 0.00892329
RGCC regulator of cell cycle 0.00885119
HOPX HOP homeobox 0.00880515
BEX1 brain expressed, X-linked 1 0.00879136
GSAP gamma-secretase activating protein 0.00878233
TSPAN5 tetraspanin 5 0.00871565
MMP9 matrix metallopeptidase 9 0.00867125
PLPBP pyridoxal phosphate binding protein 0.00863144
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.0086165
SCD5 stearoyl-CoA desaturase 5 0.00858755
ARG1 arginase 1 0.00857359
TACSTD2 tumor-associated calcium signal transducer 2 0.00851186
ACAT2 acetyl-CoA acetyltransferase 2 0.00847699
RIDA reactive intermediate imine deaminase A homolog 0.00840103
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.00839041
EDEM3 ER degradation enhancer, mannosidase alpha-like 3 0.00832863
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 0.00823572
CTSS cathepsin S 0.00820011
SCGB2A1 secretoglobin, family 2A, member 1 0.00816891
EXOC5 exocyst complex component 5 0.00807235
CA2 carbonic anhydrase II 0.00793582
TMEM158 transmembrane protein 158 (gene/pseudogene) 0.00791151
DCK deoxycytidine kinase 0.0078967
ADORA2B adenosine A2b receptor 0.00786351
KRCC1 lysine-rich coiled-coil 1 0.00786262
NDFIP1 Nedd4 family interacting protein 1 0.00783378
NRN1 neuritin 1 0.00782314
ASCL1 achaete-scute family bHLH transcription factor 1 0.00774582
CHI3L2 chitinase 3-like 2 0.00772567
GBP1 guanylate binding protein 1, interferon-inducible 0.00768067
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.00764314
MREG melanoregulin 0.00761777
HBB hemoglobin, beta 0.00758312
DHFR dihydrofolate reductase 0.00755734
PTPRO protein tyrosine phosphatase, receptor type, O 0.00755444
ADM adrenomedullin 0.00755166
LMNB1 lamin B1 0.00755025
COMMD8 COMM domain containing 8 0.00755008
VSNL1 visinin-like 1 0.00753598
CD58 CD58 molecule 0.00745693
ERLIN2 ER lipid raft associated 2 0.00744921
GINS1 GINS complex subunit 1 (Psf1 homolog) 0.00743798
CD59 CD59 molecule, complement regulatory protein 0.00742883
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 0.00740866
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 0.00739357
GLTP glycolipid transfer protein 0.00733162
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.00731551
F2R coagulation factor II (thrombin) receptor 0.00728686
ADAT1 adenosine deaminase, tRNA-specific 1 0.00728284
SLC26A2 solute carrier family 26 (anion exchanger), member 2 0.00726867
CYB5R4 cytochrome b5 reductase 4 0.00718526
LY96 lymphocyte antigen 96 0.00717701
MMP8 matrix metallopeptidase 8 0.0071576
SPRR1B small proline-rich protein 1B 0.00712466
PEA15 phosphoprotein enriched in astrocytes 15 0.00711239
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.00707678
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 0.00707273
ESR1 estrogen receptor 1 0.00706108
CEL carboxyl ester lipase 0.00703058
ACOT13 acyl-CoA thioesterase 13 0.00699292
SCRG1 stimulator of chondrogenesis 1 0.0069454
RPA3 replication protein A3, 14kDa 0.00693608
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.0069259
TYRP1 tyrosinase-related protein 1 0.00691371
CD69 CD69 molecule 0.00689752
PAH phenylalanine hydroxylase 0.00688366
RPRD1A regulation of nuclear pre-mRNA domain containing 1A 0.00687966
GPM6A glycoprotein M6A 0.00684569
TMEM50B transmembrane protein 50B 0.00676977
IFI16 interferon, gamma-inducible protein 16 0.00667261
PCLAF PCNA clamp associated factor 0.00661221
NPR3 natriuretic peptide receptor 3 0.0066036
PADI2 peptidyl arginine deiminase, type II 0.00657932
EVI2A ecotropic viral integration site 2A 0.00657136
CD52 CD52 molecule 0.006555
LYPLA1 lysophospholipase I 0.00654776
CLDN8 claudin 8 0.00653544
CD83 CD83 molecule 0.00652358
SLC35A5 solute carrier family 35, member A5 0.00652148
GRAMD2B GRAM domain containing 2B 0.00652058
LEF1 lymphoid enhancer-binding factor 1 0.00647252
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.0064589
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 0.00645768
SCAMP1 secretory carrier membrane protein 1 0.00644177
SKP1 S-phase kinase-associated protein 1 0.00641358
CDC42 cell division cycle 42 0.00640254
C3ORF14 chromosome 3 open reading frame 14 0.00634715
TIMP3 TIMP metallopeptidase inhibitor 3 0.00634383
OPHN1 oligophrenin 1 0.00633761
FZD6 frizzled class receptor 6 0.00633281
ALCAM activated leukocyte cell adhesion molecule 0.00631551
PDE4B phosphodiesterase 4B, cAMP-specific 0.00624305
GNAS GNAS complex locus 0.00623795
MRPL13 mitochondrial ribosomal protein L13 0.00623761
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 0.00622878
ERAP1 endoplasmic reticulum aminopeptidase 1 0.00622554
NDRG2 NDRG family member 2 0.00622116
CD164 CD164 molecule, sialomucin 0.00620331
CHIT1 chitinase 1 (chitotriosidase) 0.00620074
FCGBP Fc fragment of IgG binding protein 0.0061952
ADAM19 ADAM metallopeptidase domain 19 0.00617609
ALOX5AP arachidonate 5-lipoxygenase-activating protein 0.00616729
TPM4 tropomyosin 4 0.00615024
TMX1 thioredoxin-related transmembrane protein 1 0.00614997
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 0.00613476
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 0.00613056
ANKRD46 ankyrin repeat domain 46 0.0061297
PIGK phosphatidylinositol glycan anchor biosynthesis, class K 0.00612873
ACYP2 acylphosphatase 2, muscle type 0.00612279
TREM1 triggering receptor expressed on myeloid cells 1 0.00610165
ASF1A anti-silencing function 1A histone chaperone 0.00609629
F3 coagulation factor III (thromboplastin, tissue factor) 0.00607493
CANX calnexin 0.00606261
TIPRL TOR signaling pathway regulator 0.00605673
RGS4 regulator of G-protein signaling 4 0.0060537
GNA13 guanine nucleotide binding protein (G protein), alpha 13 0.00603612
GCA grancalcin, EF-hand calcium binding protein 0.00602159
CGRRF1 cell growth regulator with ring finger domain 1 0.00601973
LAPTM5 lysosomal protein transmembrane 5 0.00597268
YIPF5 Yip1 domain family, member 5 0.005972
ADAM28 ADAM metallopeptidase domain 28 0.00597137
MAT2B methionine adenosyltransferase II, beta 0.00595924
PDIA3 protein disulfide isomerase family A, member 3 0.00595213
GTPBP8 GTP-binding protein 8 (putative) 0.00593966
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.00593076
THBS2 thrombospondin 2 0.00592476
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 0.00592299
SDC2 syndecan 2 0.00591297
ACSL5 acyl-CoA synthetase long-chain family member 5 0.00590583
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 0.00590064
RPL36 ribosomal protein L36 0.00589623
ZNF274 zinc finger protein 274 0.00589353
WEE1 WEE1 G2 checkpoint kinase 0.00588624
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.00588306
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.00587655
COL11A1 collagen, type XI, alpha 1 0.00587654
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 0.00587298
KCTD20 potassium channel tetramerization domain containing 20 0.00586994
ZNF264 zinc finger protein 264 0.00586385
CLCA4 chloride channel accessory 4 0.0058547
NCK1 NCK adaptor protein 1 0.00584267
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) 0.00584186
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 0.00583998
GUSBP3 glucuronidase, beta pseudogene 3 0.00580845
CXCL10 chemokine (C-X-C motif) ligand 10 0.00580424
CLDND1 claudin domain containing 1 0.00575761
C12ORF29 chromosome 12 open reading frame 29 0.00574347
PLS3 plastin 3 0.00573286
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.00572027
CCNE2 cyclin E2 0.00570726
RFC5 replication factor C (activator 1) 5, 36.5kDa 0.00570405
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 0.00567734
F12 coagulation factor XII (Hageman factor) 0.0056723
CLEC2B C-type lectin domain family 2, member B 0.00566761
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.00565667
HTRA1 HtrA serine peptidase 1 0.00565369
RTP4 receptor (chemosensory) transporter protein 4 0.00565316
CD300A CD300a molecule 0.00565218
CCNC cyclin C 0.00564457
ETV1 ets variant 1 0.00561857
HCRTR1 hypocretin (orexin) receptor 1 0.00561556
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 0.00559492
RCAN1 regulator of calcineurin 1 0.00558911
CD53 CD53 molecule 0.00558756
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 0.00558185
SEPP1 selenoprotein P, plasma, 1 0.00557682
NIP7 NIP7, nucleolar pre-rRNA processing protein 0.00556959
CCL14 chemokine (C-C motif) ligand 14 0.00556664
MARCKS myristoylated alanine-rich protein kinase C substrate 0.00554271
MAGT1 magnesium transporter 1 0.00554053
TOX thymocyte selection-associated high mobility group box 0.00553296
PMP2 peripheral myelin protein 2 0.00552583
KIAA0226L KIAA0226-like 0.00550078
DOK5 docking protein 5 0.00549491
CPQ carboxypeptidase Q 0.00548949
ADD3 adducin 3 (gamma) 0.00548715
PECR peroxisomal trans-2-enoyl-CoA reductase 0.00548673
FAR2 fatty acyl CoA reductase 2 0.00548485
MARCH3 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase 0.00548317
MSR1 macrophage scavenger receptor 1 0.00548007
AZGP1 alpha-2-glycoprotein 1, zinc-binding 0.0054796
HLA-DRA major histocompatibility complex, class II, DR alpha 0.00547641
DUT deoxyuridine triphosphatase 0.00546218
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 0.00546128
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial 0.00545991
FGFR3 fibroblast growth factor receptor 3 0.00545269
CNIH1 cornichon family AMPA receptor auxiliary protein 1 0.00541071
TMEM230 transmembrane protein 230 0.00540802
GYPC glycophorin C (Gerbich blood group) 0.00538985
AKT3 v-akt murine thymoma viral oncogene homolog 3 0.00538839
RNASE6 ribonuclease, RNase A family, k6 0.0053877
MOCS2 molybdenum cofactor synthesis 2 0.00538595
ZNF277 zinc finger protein 277 0.00538283
LOX lysyl oxidase 0.00538202
PRR5L proline rich 5 like 0.00538109
KRT15 keratin 15, type I 0.00537658
COMMD10 COMM domain containing 10 0.00537574
NUP37 nucleoporin 37kDa 0.00535181
TSPAN7 tetraspanin 7 0.00535034
RGS10 regulator of G-protein signaling 10 0.00534879
LY75 lymphocyte antigen 75 0.00534817
DPYSL3 dihydropyrimidinase-like 3 0.00534478
DIPK1A divergent protein kinase domain 1A 0.00532506
RAD23B RAD23 homolog B (S. cerevisiae) 0.00531578
LRRC40 leucine rich repeat containing 40 0.00531429
NREP neuronal regeneration related protein 0.00531415
STK17A serine/threonine kinase 17a 0.00530702
ATG5 autophagy related 5 0.0053008
SKAP2 src kinase associated phosphoprotein 2 0.00530057
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 0.00529964
THBS1 thrombospondin 1 0.0052918
THAP1 THAP domain containing, apoptosis associated protein 1 0.0052909
MRPL39 mitochondrial ribosomal protein L39 0.00528108
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) 0.00527741
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 0.00527601
TLR4 toll-like receptor 4 0.00527563
LSM1 LSM1, U6 small nuclear RNA associated 0.00526894
CTSD cathepsin D 0.0052671
RSAD2 radical S-adenosyl methionine domain containing 2 0.0052617
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.00525414
FOXG1 forkhead box G1 0.00525183
TP63 tumor protein p63 0.00524913
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 0.00524637
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.00524066
RBBP8 retinoblastoma binding protein 8 0.00524027
RGS1 regulator of G-protein signaling 1 0.00523561
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 0.00523101
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) 0.00522023
NOX1 NADPH oxidase 1 0.00521724
PRKCQ protein kinase C, theta 0.00520968
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 0.00519882

decreased expression

Symbol Name Standardized Value
HSPA1A heat shock 70kDa protein 1A -0.0143512
PLAAT3 phospholipase A and acyltransferase 3 -0.0128523
AKR1C2 aldo-keto reductase family 1, member C2 -0.0124463
SSBP2 single-stranded DNA binding protein 2 -0.0124074
AKR1C1 aldo-keto reductase family 1, member C1 -0.0115841
OSR2 odd-skipped related transciption factor 2 -0.0115551
ASS1 argininosuccinate synthase 1 -0.0115482
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0110334
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 -0.0109889
MGLL monoglyceride lipase -0.00991423
S100P S100 calcium binding protein P -0.00975063
TSPAN8 tetraspanin 8 -0.00965507
NPTX2 neuronal pentraxin II -0.00935553
REG1A regenerating islet-derived 1 alpha -0.00932447
TGM2 transglutaminase 2 -0.00923871
AGR2 anterior gradient 2 -0.00900079
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.00885083
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.00881952
TGFBI transforming growth factor, beta-induced, 68kDa -0.00878585
AMDHD2 amidohydrolase domain containing 2 -0.00878431
PLXNB2 plexin B2 -0.00854698
FKBP11 FK506 binding protein 11, 19 kDa -0.00846443
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type -0.00836215
SIDT2 SID1 transmembrane family, member 2 -0.00819701
AKR1C3 aldo-keto reductase family 1, member C3 -0.00818589
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.00815546
TACC2 transforming, acidic coiled-coil containing protein 2 -0.00806249
ODC1 ornithine decarboxylase 1 -0.00803349
LPCAT1 lysophosphatidylcholine acyltransferase 1 -0.00788069
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 -0.00783438
MMP1 matrix metallopeptidase 1 -0.00780681
AFF1 AF4/FMR2 family, member 1 -0.00758117
RBM47 RNA binding motif protein 47 -0.00753602
NEFH neurofilament, heavy polypeptide -0.00752998
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -0.00749831
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 -0.00742225
NBEA neurobeachin -0.00729479
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.00728078
TMC5 transmembrane channel-like 5 -0.0072761
ANKRD10 ankyrin repeat domain 10 -0.0072729
UBR4 ubiquitin protein ligase E3 component n-recognin 4 -0.00725059
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 -0.0072257
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 -0.00718271
APOD apolipoprotein D -0.0071651
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -0.00716105
HSPA6 heat shock 70kDa protein 6 (HSP70B') -0.00713316
MALL mal, T-cell differentiation protein-like -0.00702339
MVP major vault protein -0.00701214
PRSS3 protease, serine, 3 -0.00697014
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -0.00695269
GULP1 GULP, engulfment adaptor PTB domain containing 1 -0.00694388
KLC1 kinesin light chain 1 -0.00691663
EGR1 early growth response 1 -0.00690944
GALC galactosylceramidase -0.00689253
TYMP thymidine phosphorylase -0.00689066
QPRT quinolinate phosphoribosyltransferase -0.00688842
PMEPA1 prostate transmembrane protein, androgen induced 1 -0.00688609
FAM13A family with sequence similarity 13, member A -0.00683605
IGFBP6 insulin-like growth factor binding protein 6 -0.00682786
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 -0.00680803
KANK2 KN motif and ankyrin repeat domains 2 -0.006803
DES desmin -0.0067939
PFKM phosphofructokinase, muscle -0.00677212
CDA cytidine deaminase -0.00676083
JAK1 Janus kinase 1 -0.00675862
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -0.00670908
COPG1 coatomer protein complex, subunit gamma 1 -0.00665827
FAM50A family with sequence similarity 50, member A -0.00665534
HDLBP high density lipoprotein binding protein -0.00661493
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa -0.00661011
NAXD NAD(P)HX dehydratase -0.00660172
CXCL5 chemokine (C-X-C motif) ligand 5 -0.00657698
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 -0.00657023
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -0.00655065
IRS2 insulin receptor substrate 2 -0.00653878
AHNAK2 AHNAK nucleoprotein 2 -0.00646151
ADGRE5 adhesion G protein-coupled receptor E5 -0.00644706
ZNF532 zinc finger protein 532 -0.00644608
TFPI2 tissue factor pathway inhibitor 2 -0.00638251
TFF1 trefoil factor 1 -0.00637478
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B -0.00637303
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) -0.00636299
TBCD tubulin folding cofactor D -0.00635232
NVL nuclear VCP-like -0.00634093
RRAD Ras-related associated with diabetes -0.00631772
NELL2 NEL-like 2 (chicken) -0.00631446
MAGEA3 melanoma antigen family A3 -0.00631132
DPP4 dipeptidyl-peptidase 4 -0.0063061
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 -0.00629411
GOLGB1 golgin B1 -0.006292
COL15A1 collagen, type XV, alpha 1 -0.00628611
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5 -0.00628519
MLPH melanophilin -0.00628286
HSPH1 heat shock 105kDa/110kDa protein 1 -0.00627059
MBOAT7 membrane bound O-acyltransferase domain containing 7 -0.00626055
PICALM phosphatidylinositol binding clathrin assembly protein -0.00625679
DCLK1 doublecortin-like kinase 1 -0.00623194
YBX3 Y box binding protein 3 -0.00623064
DVL1 dishevelled segment polarity protein 1 -0.00621864
INPP5A inositol polyphosphate-5-phosphatase, 40kDa -0.00621472
SCUBE2 signal peptide, CUB domain, EGF-like 2 -0.00618991
COL6A2 collagen, type VI, alpha 2 -0.00617329
CPT1A carnitine palmitoyltransferase 1A (liver) -0.00615525
RHOD ras homolog family member D -0.00614424
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) -0.00614163
GAB2 GRB2-associated binding protein 2 -0.00611721
STC1 stanniocalcin 1 -0.00609992
MNT MAX network transcriptional repressor -0.00609403
ACP3 acid phosphatase 3 -0.00608416
BIK BCL2-interacting killer (apoptosis-inducing) -0.00607456
GRB14 growth factor receptor-bound protein 14 -0.00606934
CARD10 caspase recruitment domain family, member 10 -0.00606548
ADIRF adipogenesis regulatory factor -0.00604215
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -0.00603514
TPPP3 tubulin polymerization-promoting protein family member 3 -0.00599704
COL16A1 collagen, type XVI, alpha 1 -0.00598613
PAEP progestagen-associated endometrial protein -0.00598553
FBLN1 fibulin 1 -0.00595408
AOC3 amine oxidase, copper containing 3 -0.00593359
LAMP1 lysosomal-associated membrane protein 1 -0.00588804
ADCY1 adenylate cyclase 1 (brain) -0.00587114
MRPS2 mitochondrial ribosomal protein S2 -0.00586837
SEC16A SEC16 homolog A (S. cerevisiae) -0.0058623
LTBP4 latent transforming growth factor beta binding protein 4 -0.00586116
WARS1 tryptophanyl-tRNA synthetase 1 -0.00585624
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -0.00585176
MISP mitotic spindle positioning -0.00585122
HIP1R huntingtin interacting protein 1 related -0.00583879
COCH cochlin -0.00583662
MYRF myelin regulatory factor -0.00582523
GPRC5C G protein-coupled receptor, class C, group 5, member C -0.00581981
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.00581649
KIAA0100 KIAA0100 -0.00580718
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast) -0.00579248
SMAD7 SMAD family member 7 -0.00574152
ACADVL acyl-CoA dehydrogenase, very long chain -0.00572519
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase -0.00572373
UPP1 uridine phosphorylase 1 -0.00568837
TUBGCP2 tubulin, gamma complex associated protein 2 -0.00568513
TPM2 tropomyosin 2 (beta) -0.00567368
REEP1 receptor accessory protein 1 -0.00566956
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1 -0.00566022
MAGEB2 melanoma antigen family B2 -0.00562966
WDR13 WD repeat domain 13 -0.00561634
IL1R1 interleukin 1 receptor, type I -0.00560895
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -0.00559855
TSPAN15 tetraspanin 15 -0.00559146
SASH1 SAM and SH3 domain containing 1 -0.00558712
LIMCH1 LIM and calponin homology domains 1 -0.00557557
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -0.00557381
MMP3 matrix metallopeptidase 3 -0.00557333
RBPMS RNA binding protein with multiple splicing -0.005563
S100A4 S100 calcium binding protein A4 -0.00555745
KCNK3 potassium channel, two pore domain subfamily K, member 3 -0.00554555
CTBP2 C-terminal binding protein 2 -0.00553418
MRPL12 mitochondrial ribosomal protein L12 -0.00553227
MXD4 MAX dimerization protein 4 -0.00552576
TM4SF4 transmembrane 4 L six family member 4 -0.00552492
CXCL2 chemokine (C-X-C motif) ligand 2 -0.00551914
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -0.00551735
ISYNA1 inositol-3-phosphate synthase 1 -0.0054998
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) -0.00546336
FXR1 fragile X mental retardation, autosomal homolog 1 -0.00546148
PDE10A phosphodiesterase 10A -0.00544625
ADCY9 adenylate cyclase 9 -0.00543789
PLEC plectin -0.00543686
BMP2 bone morphogenetic protein 2 -0.00543522
SEC31A SEC31 homolog A (S. cerevisiae) -0.00542465
LAMB2 laminin, beta 2 (laminin S) -0.00542071
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like -0.00541764
WNT5B wingless-type MMTV integration site family, member 5B -0.00541136
CNOT4 CCR4-NOT transcription complex, subunit 4 -0.00540221
NBL1 neuroblastoma 1, DAN family BMP antagonist -0.00540063
MAGEA12 melanoma antigen family A12 -0.00539993
NADSYN1 NAD synthetase 1 -0.005395
DST dystonin -0.0053942
PSCA prostate stem cell antigen -0.00537857
GOLM1 golgi membrane protein 1 -0.00537586
PLXND1 plexin D1 -0.00537102
ATP13A1 ATPase type 13A1 -0.00536755
THSD7A thrombospondin, type I, domain containing 7A -0.00536116
C14ORF132 chromosome 14 open reading frame 132 -0.00535997
SYBU syntabulin (syntaxin-interacting) -0.0053582
TM4SF20 transmembrane 4 L six family member 20 -0.0053504
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 -0.00532418
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase -0.00531189
OLFM4 olfactomedin 4 -0.00530613
ARHGAP17 Rho GTPase activating protein 17 -0.00529601
RALB v-ral simian leukemia viral oncogene homolog B -0.00528951
NR4A1 nuclear receptor subfamily 4, group A, member 1 -0.0052756
AMH anti-Mullerian hormone -0.00527251
PPARG peroxisome proliferator-activated receptor gamma -0.00526909
KLK11 kallikrein-related peptidase 11 -0.00526176
FGF13 fibroblast growth factor 13 -0.0052609
ECPAS Ecm29 proteasome adaptor and scaffold -0.0052491
LTBP2 latent transforming growth factor beta binding protein 2 -0.0052487
PINK1 PTEN induced putative kinase 1 -0.00523661
RGS5 regulator of G-protein signaling 5 -0.00523645
SRRT serrate, RNA effector molecule -0.00523276
LAMB3 laminin, beta 3 -0.00522106
FHL2 four and a half LIM domains 2 -0.00521435
POU2AF1 POU class 2 associating factor 1 -0.00520296
GRK5 G protein-coupled receptor kinase 5 -0.00520026
SIK3 SIK family kinase 3 -0.00519909
HSPB8 heat shock 22kDa protein 8 -0.00519631
CYFIP2 cytoplasmic FMR1 interacting protein 2 -0.00519357
RUFY2 RUN and FYVE domain containing 2 -0.00519118
H1-2 H1.2 linker histone, cluster member -0.00518915
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 -0.00518708
GAS6 growth arrest-specific 6 -0.00518596
MICALL2 MICAL-like 2 -0.00518294
RUNX3 runt-related transcription factor 3 -0.00518267
TST thiosulfate sulfurtransferase (rhodanese) -0.00518076
RABAC1 Rab acceptor 1 (prenylated) -0.00517591
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 -0.00516851
HIST1H2BK histone cluster 1, H2bk -0.00516604
LUC7L3 LUC7-like 3 (S. cerevisiae) -0.0051657
SLC39A4 solute carrier family 39 (zinc transporter), member 4 -0.00516473
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 -0.00515941
ABHD4 abhydrolase domain containing 4 -0.00515255
HGS hepatocyte growth factor-regulated tyrosine kinase substrate -0.00515244
COL9A2 collagen, type IX, alpha 2 -0.00515141
ITPK1 inositol-tetrakisphosphate 1-kinase -0.0051441
DPT dermatopontin -0.00514042
ARHGAP21 Rho GTPase activating protein 21 -0.00513749
NID2 nidogen 2 (osteonidogen) -0.0051332
MYO5C myosin VC -0.00512947
SLIT2 slit homolog 2 (Drosophila) -0.00512488
CHMP4A charged multivesicular body protein 4A -0.00511816
EPRS1 glutamyl-prolyl-tRNA synthetase 1 -0.00508738
IGF2R insulin-like growth factor 2 receptor -0.00508713
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.00508161
COL7A1 collagen, type VII, alpha 1 -0.00506904
GARS1 glycyl-tRNA synthetase 1 -0.0050666
RABEP2 rabaptin, RAB GTPase binding effector protein 2 -0.00506561
FOSB FBJ murine osteosarcoma viral oncogene homolog B -0.00506203
SH3BP4 SH3-domain binding protein 4 -0.00506023
YY1AP1 YY1 associated protein 1 -0.00504952
PCSK5 proprotein convertase subtilisin/kexin type 5 -0.00503968
KYNU kynureninase -0.00503318
KCTD5 potassium channel tetramerization domain containing 5 -0.00503282
PROCR protein C receptor, endothelial -0.00502291
MYH11 myosin, heavy chain 11, smooth muscle -0.00501355
MCOLN1 mucolipin 1 -0.00501171
ERCC5 excision repair cross-complementation group 5 -0.00500813
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -0.00498828
MFAP4 microfibrillar-associated protein 4 -0.00498293
DEGS1 delta(4)-desaturase, sphingolipid 1 -0.00498051
KLK2 kallikrein-related peptidase 2 -0.00498023